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Volumn 62, Issue 2, 1996, Pages 181-191

A phase I/II study of dose-intense paclitaxel with cisplatin and cyclophosphamide as initial therapy of poor-prognosis advanced-stage epithelial ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ANTIHISTAMINIC AGENT; CA 125 ANTIGEN; CIMETIDINE; CISPLATIN; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DIPHENHYDRAMINE; GRANULOCYTE COLONY STIMULATING FACTOR; NARCOTIC AGENT; PACLITAXEL;

EID: 0030221059     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.1996.0213     Document Type: Article
Times cited : (31)

References (56)
  • 1
    • 0001802909 scopus 로고
    • Cancer of the ovary
    • (V. T. DeVita, S. Hellman, and S. A. Rosenberg, Eds.), Lippincott, Philadelphia, 4th ed.
    • 1. Young, R. C., Perez, C. A., and Hoskins, W. J. Cancer of the ovary, in Cancer: Principles and practice of oncology (V. T. DeVita, S. Hellman, and S. A. Rosenberg, Eds.), Lippincott, Philadelphia, 4th ed., pp. 1226-1263 (1993).
    • (1993) Cancer: Principles and Practice of Oncology , pp. 1226-1263
    • Young, R.C.1    Perez, C.A.2    Hoskins, W.J.3
  • 3
    • 0029067255 scopus 로고
    • Paclitaxel (Taxol), cisplatin and cyclophosphamide in human ovarian cancer: Molecular rationale and early clinical results
    • 3. Reed, E., Kohn, E. C., Sarosy, G., Dabholkar, M., Davis, P., Jacob, J., and Maher, M. Paclitaxel (Taxol), cisplatin and cyclophosphamide in human ovarian cancer: Molecular rationale and early clinical results, Semin. Oncol. 22, 90-96 (1995).
    • (1995) Semin. Oncol. , vol.22 , pp. 90-96
    • Reed, E.1    Kohn, E.C.2    Sarosy, G.3    Dabholkar, M.4    Davis, P.5    Jacob, J.6    Maher, M.7
  • 4
    • 0026647319 scopus 로고
    • Dose-intensive induction therapy with cyclophosphamide, cisplatin, and consolidative abdominal radiation in advanced-stage epithelial ovarian cancer
    • 4. Rothenberg, M. C., Ozols, R. F., Young, R. C., Glatstein, E. J., Steinberg, S. M., and Reed, E. Dose-intensive induction therapy with cyclophosphamide, cisplatin, and consolidative abdominal radiation in advanced-stage epithelial ovarian cancer, J. Clin. Oncol. 10, 727-734 (1992).
    • (1992) J. Clin. Oncol. , vol.10 , pp. 727-734
    • Rothenberg, M.C.1    Ozols, R.F.2    Young, R.C.3    Glatstein, E.J.4    Steinberg, S.M.5    Reed, E.6
  • 6
    • 0011879579 scopus 로고
    • A phase III trial of dose intense versus standard dose cisplatin and cytoxan in advanced ovarian cancer
    • 6. McGuire, W. P., Hoskins, W. J., Brady, M. F., Homesly, H., and Clarke-Pearson, D. L. A phase III trial of dose intense versus standard dose cisplatin and cytoxan in advanced ovarian cancer, Proc. ASCO 11, 226 (1992).
    • (1992) Proc. ASCO , vol.11 , pp. 226
    • McGuire, W.P.1    Hoskins, W.J.2    Brady, M.F.3    Homesly, H.4    Clarke-Pearson, D.L.5
  • 7
    • 0027520058 scopus 로고
    • Importance of multiagent chemotherapy regimens in ovarian carcinoma: Dose intensity analysis
    • 7. Levin, L., Simon, R., and Hryniuk, W. M. Importance of multiagent chemotherapy regimens in ovarian carcinoma: Dose intensity analysis, J. Natl. Cancer Inst. 85, 1732-1742 (1993).
    • (1993) J. Natl. Cancer Inst. , vol.85 , pp. 1732-1742
    • Levin, L.1    Simon, R.2    Hryniuk, W.M.3
  • 8
    • 0023259838 scopus 로고
    • Dose intensity analysis of chemotherapy regimens in ovarian cancer
    • 8. Levin, L., and Hyrniuk, W. M. Dose intensity analysis of chemotherapy regimens in ovarian cancer, J. Clin. Oncol. 5, 756-767 (1987).
    • (1987) J. Clin. Oncol. , vol.5 , pp. 756-767
    • Levin, L.1    Hyrniuk, W.M.2
  • 11
    • 0027055485 scopus 로고
    • Phase II study and long-term follow-up of patients treated with taxol for advanced ovarian adenocarcinoma
    • 11. Einzig, A. I., Wiernik, P. H., Sasloff, J., Runowica, F. D., and Goldberg, G. L. Phase II study and long-term follow-up of patients treated with taxol for advanced ovarian adenocarcinoma, J. Clin. Oncol. 10, 1748-1753 (1992).
    • (1992) J. Clin. Oncol. , vol.10 , pp. 1748-1753
    • Einzig, A.I.1    Wiernik, P.H.2    Sasloff, J.3    Runowica, F.D.4    Goldberg, G.L.5
  • 14
    • 0028153230 scopus 로고
    • Phase II trial of paclitaxel in patients with progressive ovarian carcinoma after platinum-based chemotherapy
    • 14. Thigpen, J. T., Blessing, J. A., Ball, H., Hummel, S. J., and Barrett, R. J. Phase II trial of paclitaxel in patients with progressive ovarian carcinoma after platinum-based chemotherapy, J. Clin. Oncol. 12, 1748-1753 (1994).
    • (1994) J. Clin. Oncol. , vol.12 , pp. 1748-1753
    • Thigpen, J.T.1    Blessing, J.A.2    Ball, H.3    Hummel, S.J.4    Barrett, R.J.5
  • 15
    • 0027366246 scopus 로고
    • Paclitaxel for platinum-refractory ovarian cancer: Results from the first 1,000 patients registered to National Cancer Institute Treatment Referral Center 9103
    • 15. Trimble, E. L., Adams, J. D., Vena, D., Hawkins, M. J., Friedman, M. A., Fisherman, J. S., Christian, M. C., Canetta, R., Onetto, N., Hayn, R., et al. Paclitaxel for platinum-refractory ovarian cancer: Results from the first 1,000 patients registered to National Cancer Institute Treatment Referral Center 9103, J. Clin. Oncol. 11, 2405-2410 (1993).
    • (1993) J. Clin. Oncol. , vol.11 , pp. 2405-2410
    • Trimble, E.L.1    Adams, J.D.2    Vena, D.3    Hawkins, M.J.4    Friedman, M.A.5    Fisherman, J.S.6    Christian, M.C.7    Canetta, R.8    Onetto, N.9    Hayn, R.10
  • 16
    • 0001853427 scopus 로고
    • Controversies in the treatment of advanced ovarian cancer
    • 16. Kohn, E. C., and Reed, E. Controversies in the treatment of advanced ovarian cancer, NIH Catalyst, 17-22 (1994).
    • (1994) NIH Catalyst , pp. 17-22
    • Kohn, E.C.1    Reed, E.2
  • 17
    • 0027619786 scopus 로고
    • Taxol dose intensification and its clinical implications
    • 17. Sarosy, G., and Reed, E. Taxol dose intensification and its clinical implications, J. Natl. Med. Assoc. 85, 427-431 (1993).
    • (1993) J. Natl. Med. Assoc. , vol.85 , pp. 427-431
    • Sarosy, G.1    Reed, E.2
  • 18
    • 0002937302 scopus 로고
    • Chemotherapeutic dose intensity in ovarian cancer
    • 18. Ozols, R. F. Chemotherapeutic dose intensity in ovarian cancer, Adv. Oncol. 11, 24-29 (1995).
    • (1995) Adv. Oncol. , vol.11 , pp. 24-29
    • Ozols, R.F.1
  • 22
    • 0019961380 scopus 로고
    • Cyclophosphamide plus cis-platinum in combination: Treatment program for stage III or IV ovarian carcinoma
    • 22. Decker, D. G., Fleming, T. R., and Malkasian, G. D. Cyclophosphamide plus cis-platinum in combination: Treatment program for stage III or IV ovarian carcinoma, Obstet. Gynecol. 60, 481 (1982).
    • (1982) Obstet. Gynecol. , vol.60 , pp. 481
    • Decker, D.G.1    Fleming, T.R.2    Malkasian, G.D.3
  • 23
    • 0023239218 scopus 로고
    • Randomised comparison of cisplatin with cyclophosphamide/cisplatin and with cyclophosphamide/doxorubicin/cisplatin in advanced ovarian cancer
    • 23. Gruppo Interegionale Cooperativo Oncologico Ginecologia. Randomised comparison of cisplatin with cyclophosphamide/cisplatin and with cyclophosphamide/doxorubicin/cisplatin in advanced ovarian cancer, Lancet 2, 353-359 (1987).
    • (1987) Lancet , vol.2 , pp. 353-359
  • 24
    • 0026681465 scopus 로고
    • Long-term results of a randomized trial comparing cisplatin with cisplatin and cyclophosphamide with cisplatin, cyclophosphamide, and adriamycin in advanced ovarian cancer
    • 24. GICOG (Gruppo Interregionale Cooperativo Oncologico Ginecologia, Italy. Long-term results of a randomized trial comparing cisplatin with cisplatin and Cyclophosphamide with cisplatin, cyclophosphamide, and adriamycin in advanced ovarian cancer, Gynecol. Oncol. 45, 115-117 (1992).
    • (1992) Gynecol. Oncol. , vol.45 , pp. 115-117
  • 25
    • 0027862598 scopus 로고
    • Taxol effects on cisplatin sensitivity and cisplatin cellular accumulation in human ovarian cancer cells
    • 25. Parker, R. J., Dabholkar, M. D., Lee, K. B., Bostick-Bruton, F., and Reed, E. Taxol effects on cisplatin sensitivity and cisplatin cellular accumulation in human ovarian cancer cells, Monogr. Natl. Cancer Inst. 15, 83-88 (1993).
    • (1993) Monogr. Natl. Cancer Inst. , vol.15 , pp. 83-88
    • Parker, R.J.1    Dabholkar, M.D.2    Lee, K.B.3    Bostick-Bruton, F.4    Reed, E.5
  • 26
    • 0027502156 scopus 로고
    • The absence of cumulative bone marrow toxicity in patients with recurrent adenocarcinoma of the ovary receiving dose-intense taxol and granulocyte colony stimulating factor
    • 26. Bicher, A., Kohn, E. C., Sarosy, G., Davis, P., Adamo, D. O., Jacob, J., Christian, M., and Reed, E. The absence of cumulative bone marrow toxicity in patients with recurrent adenocarcinoma of the ovary receiving dose-intense taxol and granulocyte colony stimulating factor, Anti-Cancer Drugs 4, 141-148 (1993).
    • (1993) Anti-cancer Drugs , vol.4 , pp. 141-148
    • Bicher, A.1    Kohn, E.C.2    Sarosy, G.3    Davis, P.4    Adamo, D.O.5    Jacob, J.6    Christian, M.7    Reed, E.8
  • 27
    • 0028157157 scopus 로고
    • Flexible G-CSF dosing in ovarian cancer patients who receive dose intense Taxol therapy
    • 27. Link, C. J., Bicher, A., Kohn, E. C., Christian, M. C., Davis, P. A., Adamo, D. O., Reed, E., and Sarosy, G. A. Flexible G-CSF dosing in ovarian cancer patients who receive dose intense Taxol therapy, Blood 83, 1188-1192 (1994).
    • (1994) Blood , vol.83 , pp. 1188-1192
    • Link, C.J.1    Bicher, A.2    Kohn, E.C.3    Christian, M.C.4    Davis, P.A.5    Adamo, D.O.6    Reed, E.7    Sarosy, G.A.8
  • 29
    • 0026742779 scopus 로고
    • Hypersensitivity reactions
    • 29. Weiss, R. B. Hypersensitivity reactions, Semin. Oncol. 19, 458-477 (1992).
    • (1992) Semin. Oncol. , vol.19 , pp. 458-477
    • Weiss, R.B.1
  • 30
    • 0000941980 scopus 로고
    • A distribution-free K-sample test against ordered alternatives
    • 30. Jonckheere, A. R. A distribution-free K-sample test against ordered alternatives, Biometrika 41, 133-145 (1954).
    • (1954) Biometrika , vol.41 , pp. 133-145
    • Jonckheere, A.R.1
  • 31
    • 33845382806 scopus 로고
    • Non-parametric estimation from incomplete observations
    • 31. Kaplan, E., and Meier, P. Non-parametric estimation from incomplete observations, J. Am. Stat. Assoc. 53, 457-481 (1958).
    • (1958) J. Am. Stat. Assoc. , vol.53 , pp. 457-481
    • Kaplan, E.1    Meier, P.2
  • 32
    • 0013886333 scopus 로고
    • Evaluation of survival data and two new rank order statistics arising in its consideration
    • 32. Mantel, N. Evaluation of survival data and two new rank order statistics arising in its consideration, Cancer Chem. Rep. 50, 163-170 (1966).
    • (1966) Cancer Chem. Rep. , vol.50 , pp. 163-170
    • Mantel, N.1
  • 33
    • 0002682957 scopus 로고
    • Serous surface papillary carcinoma of the ovary: A clinical, pathologic, ultrastructural, and immunohistochemical study of 11 cases
    • 33. White, P. F., Merino, M. J., and Barwick, K. W. Serous surface papillary carcinoma of the ovary: A clinical, pathologic, ultrastructural, and immunohistochemical study of 11 cases, Pathol. Annu. 20, 403-418 (1985).
    • (1985) Pathol. Annu. , vol.20 , pp. 403-418
    • White, P.F.1    Merino, M.J.2    Barwick, K.W.3
  • 36
    • 0025860057 scopus 로고
    • Long-term follow-up and prognostic factor analysis in advanced ovarian carcinoma: The Gynecologic Oncology Group experience
    • 36. Omura, G. A., Brady, M. F., Homesley, H. D., Yordan, E., Major, F. J., Buchsbaum, H. J., and Park, R. C. Long-term follow-up and prognostic factor analysis in advanced ovarian carcinoma: The Gynecologic Oncology Group experience, J. Clin. Oncol. 9, 1138-1150 (1991).
    • (1991) J. Clin. Oncol. , vol.9 , pp. 1138-1150
    • Omura, G.A.1    Brady, M.F.2    Homesley, H.D.3    Yordan, E.4    Major, F.J.5    Buchsbaum, H.J.6    Park, R.C.7
  • 38
    • 0016586897 scopus 로고
    • Surgical resection of tumor bulk in the primary treatment of ovarian carcinoma: Symposium on ovarian cancer
    • 38. Griffiths, C. T. H. Surgical resection of tumor bulk in the primary treatment of ovarian carcinoma: Symposium on ovarian cancer, Natl. Cancer Inst. Mongr. 42, 1010-1014 (1975).
    • (1975) Natl. Cancer Inst. Mongr. , vol.42 , pp. 1010-1014
    • Griffiths, C.T.H.1
  • 40
    • 0018239343 scopus 로고
    • Advanced ovarian adenocarcinoma: A prospective clinical trial of melphalan (L-PAM) versus combination chemotherapy
    • 40. Young, R., Chabner, B., and Hubbard, S. Advanced ovarian adenocarcinoma: A prospective clinical trial of melphalan (L-PAM) versus combination chemotherapy, N. Engl. J. Med. 299, 1261 (1978).
    • (1978) N. Engl. J. Med. , vol.299 , pp. 1261
    • Young, R.1    Chabner, B.2    Hubbard, S.3
  • 42
    • 0026032160 scopus 로고
    • Carboplatin, doxorubicin, and cyclophosphamide versus cisplatin, doxorubicin, and cyclophosphamide: A randomized trial in stage III-IV epithelial ovarian carcinoma
    • 42. Conte, P. F., Bruzzone, M., Carnino, F., et al. Carboplatin, doxorubicin, and cyclophosphamide versus cisplatin, doxorubicin, and cyclophosphamide: A randomized trial in stage III-IV epithelial ovarian carcinoma, J. Clin. Oncol. 9, 658-663 (1991).
    • (1991) J. Clin. Oncol. , vol.9 , pp. 658-663
    • Conte, P.F.1    Bruzzone, M.2    Carnino, F.3
  • 44
    • 0026634982 scopus 로고
    • Improved therapeutic index of carboplatin plus cyclophosphamide versus cisplatin plus cyclophosphamide: Final report by the Southwest Oncology Group of a phase III randomized trial in stages III and IV ovarian cancer
    • 44. Alberts, D. S., Green, S., Hannigan, E. V., O'Toole, R., Stock-Novack, D., Anderson, P., Surwit, E. A., Malvlya, V. K., Nahhas, W. A., and Jolles, C. J. Improved therapeutic index of carboplatin plus cyclophosphamide versus cisplatin plus cyclophosphamide: Final report by the Southwest Oncology Group of a phase III randomized trial in stages III and IV ovarian cancer, J. Clin. Oncol. 10, 706-717 (1992).
    • (1992) J. Clin. Oncol. , vol.10 , pp. 706-717
    • Alberts, D.S.1    Green, S.2    Hannigan, E.V.3    O'Toole, R.4    Stock-Novack, D.5    Anderson, P.6    Surwit, E.A.7    Malvlya, V.K.8    Nahhas, W.A.9    Jolles, C.J.10
  • 45
    • 0018387446 scopus 로고
    • Promotion of microtubule assembly in vitro by Taxol
    • 45. Schiff, P. B., Fant, J., and Horowitz, S. B. Promotion of microtubule assembly in vitro by Taxol, Nature 277, 655-667 (1979).
    • (1979) Nature , vol.277 , pp. 655-667
    • Schiff, P.B.1    Fant, J.2    Horowitz, S.B.3
  • 46
    • 0019805521 scopus 로고
    • Taxol induced polymerization of purified tubulin
    • 46. Kumar, N. Taxol induced polymerization of purified tubulin, J. Biol. Chem. 256, 10435-10441 (1981).
    • (1981) J. Biol. Chem. , vol.256 , pp. 10435-10441
    • Kumar, N.1
  • 47
    • 0028070358 scopus 로고
    • Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase
    • 47. Long, B. H., and Fairchild, C. R. Paclitaxel inhibits progression of mitotic cells to G1 phase by interference with spindle formation without affecting other microtubule functions during anaphase and telephase, Cancer Res. 54, 4355-4361 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 4355-4361
    • Long, B.H.1    Fairchild, C.R.2
  • 48
    • 0027360552 scopus 로고
    • Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations
    • 48. Jordan, M. A., Toso, R. J., Thrower, D., and Wilson, L. Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations, Proc. Natl. Acad. Sci. USA 90, 9552-9556 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9552-9556
    • Jordan, M.A.1    Toso, R.J.2    Thrower, D.3    Wilson, L.4
  • 49
    • 0026684820 scopus 로고
    • Taxol sensitizes human astrocytoma cells to radiation
    • 49. Tishler, R. B., Geard, C. R., Hall, E. J., and Schiff, P. B. Taxol sensitizes human astrocytoma cells to radiation, Cancer Res. 52, 3494-3497 (1992).
    • (1992) Cancer Res. , vol.52 , pp. 3494-3497
    • Tishler, R.B.1    Geard, C.R.2    Hall, E.J.3    Schiff, P.B.4
  • 50
    • 0027977269 scopus 로고
    • It was a very good year for DNA repair
    • 50. Cleaver, J. E. It was a very good year for DNA repair, Cell 76, 1-4 (1994).
    • (1994) Cell , vol.76 , pp. 1-4
    • Cleaver, J.E.1
  • 51
    • 0028564949 scopus 로고
    • Mismatch repair, genetic stability, and cancer
    • 51. Modrich, P. Mismatch repair, genetic stability, and cancer, Science 266, 1959-1960(1995).
    • (1995) Science , vol.266 , pp. 1959-1960
    • Modrich, P.1
  • 52
    • 0028606403 scopus 로고
    • Mechanisms of DNA excision repair
    • 52. Sancar, A. Mechanisms of DNA excision repair, Science 266, 1954-1956 (1995).
    • (1995) Science , vol.266 , pp. 1954-1956
    • Sancar, A.1
  • 53
    • 0023945042 scopus 로고
    • Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional cell carcinoma of the urothelium
    • 53. Gabrilove, J., Jakubowski, A., Scher, H., Sternberg, C., Wong, G., Grous, J., Yagoda, A., Fain, K., Moore, M. A., and Clarkson, B. Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional cell carcinoma of the urothelium, N. Engl. J. Med. 318, 1414-1422 (1988).
    • (1988) N. Engl. J. Med. , vol.318 , pp. 1414-1422
    • Gabrilove, J.1    Jakubowski, A.2    Scher, H.3    Sternberg, C.4    Wong, G.5    Grous, J.6    Yagoda, A.7    Fain, K.8    Moore, M.A.9    Clarkson, B.10
  • 54
    • 0001473625 scopus 로고
    • Taxol and cisplatin (TP) improves outcome in advanced ovarian cancer as compared with cytoxan and cisplatin (CP)
    • 54. McGuire, W. P., Hoskins, W. J., Brady, M. F., Kucera, P. R., Partridge, E. E., Look, K. Y., and Davidson, M. Taxol and cisplatin (TP) improves outcome in advanced ovarian cancer as compared with cytoxan and cisplatin (CP), Proc. ASCO 14, 275 (1995).
    • (1995) Proc. ASCO , vol.14 , pp. 275
    • McGuire, W.P.1    Hoskins, W.J.2    Brady, M.F.3    Kucera, P.R.4    Partridge, E.E.5    Look, K.Y.6    Davidson, M.7
  • 55
    • 0022929883 scopus 로고
    • Long-term results of a cisplatin-containing combination chemotherapy regimen for the treatment of advanced ovarian carcinoma
    • 55. Louie, K. G., Ozols, R. F., Myers, C. E., Ostchega, Y., Jenkins, J., Howser, D., and Young, R. C. Long-term results of a cisplatin-containing combination chemotherapy regimen for the treatment of advanced ovarian carcinoma, J. Clin. Oncol. 4, 1579-1585 (1986).
    • (1986) J. Clin. Oncol. , vol.4 , pp. 1579-1585
    • Louie, K.G.1    Ozols, R.F.2    Myers, C.E.3    Ostchega, Y.4    Jenkins, J.5    Howser, D.6    Young, R.C.7
  • 56
    • 0024579423 scopus 로고
    • Ten-year follow-up of patients receiving cisplatin, doxorubicin, and cyclophosphamide chemotherapy for advanced epithelial ovarian carcinoma
    • 56. Sutton, G. P., Stehman, F. B., Einhorn, L. H., Roth, L. M., Blessing, J. A., and Ehrlich, C. E. Ten-year follow-up of patients receiving cisplatin, doxorubicin, and cyclophosphamide chemotherapy for advanced epithelial ovarian carcinoma, J. Clin. Oncol. 7, 223-229 (1989).
    • (1989) J. Clin. Oncol. , vol.7 , pp. 223-229
    • Sutton, G.P.1    Stehman, F.B.2    Einhorn, L.H.3    Roth, L.M.4    Blessing, J.A.5    Ehrlich, C.E.6


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