Two monoclonal antibodies from the platelet panel recognize sheep plasma fibrinogen

Veterinary Immunology and Immunopathology

Volumn 52, Issue 4, 1996, Pages 371-375

  Perez De La Lastra J M ^a   Mateo, A ^a   Dusinsky, R ^b   Simon, M ^b   Llanes, D ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; FIBRINOGEN; MONOCLONAL ANTIBODY;

CONFERENCE PAPER; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; NONHUMAN; SHEEP;

OVIS ARIES;

EID: 0030220965     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-2427(96)05589-4     Document Type: Conference Paper

References (8)

1. Cierniewski, C.S. and Budzynski, A.Z., 1992. Involvement of the alpha chain in fibrin clot formation. Effect of monoclonal antibodies. Biochemistry, 31: 4248-4253.
2. Farrell, D.H., Thiagarajan, P., Chung, D.W. and Davie, E.W., 1992. Role of fibrinogen alpha and gamma chain sites in platelet aggregation. Proc. Nat. Acad. Sci. USA, 89: 10729-10732.
3. Mateo, A., Perez de la Lastra, J.M., Moreno, A., Dusinsky, R., Bilka, F., Simon, M., Horovska, L. and Llanes, D., 1996. Biochemical characterization of antigens detected with anti-platelet monoclonal antibodies. Vet. Immunol. Immunopathol., 52: 363-370.
4. Philips, D.R., Charo, I., Parise, L. and Fitzgerald, A., 1988. The platelet membrane glycoprotein IIb/IIIa complex. Blood, 71(4): 31-843.
5. Pintado, C.O., Friend, M. and Llanes, D., 1995. Characterisation of a membrane receptor on ruminants and equine platelets and peripheral blood leukocytes similar to the human integrin receptor glycoprotein IIb/IIIa (CD41/61). Vet. Immunol. Immunopathol., 44: 359-368.
6. Pintado, C.O., Moreno, A., Pérez de la Lastra, J.M., Martín de las Mulas, J. and Llanes, D., 1996. A monoclonal antibody to ruminant fibrinogen produced through immunization with ovine peripheral blood leukocyte. Hybridoma, 15(1): 87-90.
7. Shattil, S.J., Weisel, J.W. and Kieber-Emmons, T., 1992. Use of monoclonal antibodies to study the interaction between an integrin adhesion receptor, gpIIb/IIIa, and its physiological ligand, fibrinogen. Immunomethods, 1: 53-63.
8. Warkentin, T.E., Powling, M.J. and Hardisty, R.M., 1990. Measurement of fibrinogen binding to platelets in whole blood by flow cytometry: a micromethod for the detection of platelet activation. Br. J. Haematol., 76: 387-394.