Efficient procedures for the large-scale preparation of (1S,2S)-trans-2-methoxycyclohexanol, a key chiral intermediate in the synthesis of tricyclic β-lactam antibiotics

Tetrahedron Asymmetry

Volumn 7, Issue 8, 1996, Pages 2247-2250

  Stead, Paul ^a   Marley, Hugh ^a   Mahmoudian, Mahmoud ^a   Webb, Graham ^a   Noble, David ^a   Ip, Yam To ^a   Piga, Elisabetta ^b   Rossi, Tino ^b   Roberts, Stanley ^c   Dawson, Michael J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b GSK   (Italy)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYCYCLOHEXANOL; BETA LACTAM ANTIBIOTIC; CYCLOALKANOL DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG PURIFICATION; DRUG SYNTHESIS; ENZYME ACTIVITY; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030220432     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/0957-4166(96)00279-0     Document Type: Article

References (10)

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2. 1) Tamburini B, Perboni A, Rossi T, Donati D, Andreotti D, Gaviraghi G. Carleso R and Bismara C (Glaxo S.p.A), Eur. Pat. Appl. 0 416 953 A2, 1991; Tamburini B, Rossi T, Donati D, Gaviraghi G and Tarzi G, Recent Advances in the chemistry of anti-Infective Agents, Ed. Bentley P.H and Ponsford R, Royal Society of Chemistry, Cambridge, 1992, pp 21-35.
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