Structure-activity relationships of HIV-1 PR inhibitors containing AHPBA - II. Modification of pyrrolidine ring at P1' proline

Bioorganic and Medicinal Chemistry

Volumn 4, Issue 8, 1996, Pages 1365-1377

  Komai, Tomoaki ^b   Higashida, Susumu ^a   Sakurai, Mitsuya ^a   Nitta, Tamayo ^a   Kasuya, Atsushi ^a   Miyamaoto, Shuichi ^a   Yagi, Ryuichi ^b   Ozawa, Yuji ^b   Handa, Hiroshi ^c   Mohri, Hiroshi ^d   Yasuoka, Akira ^d   Oka, Shinichi ^d   Nishigaki, Takashi ^b   Kimura, Satoshi ^d   Shimada, Kaoru ^d   Yabe, Yuichiro ^a  

^a Exploratory Chemistry Research   (Japan)

^b DAIICHI SANKYO CO   (Japan)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; PROTEINASE; PROTEINASE INHIBITOR;

ANTIVIRAL ACTIVITY; ARTICLE; CHIRALITY; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; INFRARED SPECTROPHOTOMETRY; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030220262     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/0968-0896(96)00130-7     Document Type: Article

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