Angiotensin-converting enzyme and heart chymase gene polymorphisms in hypertrophic cardiomyopathy

American Journal of Cardiology

Volumn 78, Issue 3, 1996, Pages 362-364

  Pfeufer, Arne ^a   Osterziel, Karl Josef ^a   Urata, Hidenori ^a   Borck, Guntram ^a   Schuster, Herbert ^a   Wienker, Thomas ^a   Dietz, Rainer ^a   Luft, Friedrich C ^a,b  

^a HUMBOLDT UNIVERSITY   (Germany)

^b FRANZ VOLHARD CLINIC   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHYMASE; DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENOTYPE; HETEROZYGOSITY; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; MALE; PRIORITY JOURNAL;

EID: 0030220174     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(96)00296-2     Document Type: Article

References (7)

1. Marian A, Yu Q, Workman R., Gottfried G., Roberts R. Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden death. Lancet. 342:1993;1085-1086.
2. Urata H, Boehm KD, Philip A, Kinoshita A, Gabrovsek J, Bumpus FM, Husain A Cellular localization and regional distribution of an angiotensin II-forming chymase in the heart. J Clin Invest. 91:1993;1269-1281.
3. Urata H, Kinoshita A, Perez DM, Misono KS, Bumpus FM, Graham BM, Husain A Cloning of the gene and cDNA for human heart chymase. J Biol Chem. 266:1991;17173-17179.
4. Henry WL, Clark CE, Glancy DL, Epstein SE Echocardiographic measurement of the left ventricular outflow gradient in idiopathic hypertrophic subaortic stenosis. N Engl J Med. 288:1973;989-993.
5. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F An insertion/deletion polymorphism in the angiotensin 1-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest. 86:1990;1343-1346.
6. Lindpaintner K, Pfeffer MA, Kreutz R, Stampfer MJ, Grodstein F, LaMotte F, Buring J, Hennekens CH A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med. 332:1995;706-711.
7. Lechin M, Quiñones MA, Omran A, Hill R, Yu Q-T, Rakowski H, Wigle D, Liew CC, Sole M, Roberts R, Marian AJ Angiotensin-I converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy. Circulation. 92:1995;1808-1812.