Activation of Murine Lymphocytes by Lipopolysaccharide Incorporated in Fusogenic, Reconstituted Influenza Virus Envelopes (Virosomes)

Journal of Immunology

Volumn 157, Issue 3, 1996, Pages 1028-1036

  Dijkstra, Jan ^a,b,c   Bron, Romke ^b   Wilschut, Jan ^b   De Haan, Aalzen ^b   Ryan, John L ^a,d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c ENTREMED INC   (United States)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN KAPPA CHAIN; LIPOPOLYSACCHARIDE; LIPOSOME; VIRUS ENVELOPE PROTEIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; ELECTRON MICROSCOPY; FEMALE; IMMUNOLOGY; IN VITRO STUDY; LYMPHOCYTE ACTIVATION; MOUSE; ORTHOMYXOVIRUS; PH; ULTRASTRUCTURE;

ANIMALS; FEMALE; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN KAPPA-CHAINS; LIPOPOLYSACCHARIDES; LIPOSOMES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON; ORTHOMYXOVIRIDAE; VIRAL ENVELOPE PROTEINS;

EID: 0030210874     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Morrison, D. C., and J. L. Ryan. 1979. Bacterial endotoxin and host immune responses. Adv. Immunol. 28:293.
2. Morrison, D. C., and J. L. Ryan. 1987. Endotoxins and disease mechanisms. Annu. Rev. Med. 38:417.
3. Morrison, D. C. 1985. Nonspecific interactions of bacterial lipopolysaccharides with membranes and membrane components. In Handbook of Endotoxin, Vol. 3: Cellular Biology of Endotoxin. L. J. Berry, ed. Elsevier, Amsterdam, p. 25.
4. Tahri-Jouti, M.-A., and R. Chaby. 1990. Specific binding of lipopolysaccharides to mouse macrophages. I. Characteristics of the interaction and inefficiency of the polysaccharide region. Mol. Immunol. 27:751.
5. Jacobs, D. M. 1992. Structural features of binding of lipopolysaccharide to murine lymphocytes. Rer. Infect. Dis. 6:5012.
6. Jackson, S. K., P. E. James, C. C. Rowlands, and B. Mile. 1992. Binding of endotoxin to macrophages; interactions of spin-labeled saccharide residues. Biochim. Biophys. Acta 1135:165.
7. Haeffner-Cavaillon, N., J. M. Cavaillon, and L. Szabo. 1985. Cellular receptors for endotoxin. In Handbook of Endotoxin, Vol. 3: Cellular Biology of Endotoxin. L. J. Berry, ed. Elsevier, Amsterdam, p. 1.
8. Hampton, R. Y., D. T. Golenbock, and C. R. H. Raetz. 1988. Lipid A binding sites in membranes of macrophage tumor cells. J. Biol. Chem. 263:14802.
9. Kirklard, T. N., G. D. Virca, T. Kuus-Reichel, F. K. Multer, S. Y. Kim, R. J. Ulevitch, and P. S. Tobias. 1990. Identification of lipopolysaccharide-binding proteins in 70Z/3 cells by photoaffinity cross-linking. J. Biol. Chem. 265:9520.
10. Hara-Kuge, S., F. Amano, M. Nishijima, and Y. Akamatsu. 1990. Isolation of a lipopolysaccharide (LPS)-resistant mutant, with defective LPS binding, of cultured macrophage-like cells. J. Biol. Chem. 265:6606.
11. Golenbock, D. T., R. Y. Hampton, C. R. H. Raetz, and S. D. Wright. 1990. Human phagocytes have multiple lipid A-binding sites. Infect. Immun. 58:4069.
12. Lei, M.-G., S. A. L. Stimpson, and D. C. Morrison. 1991. Specific endotoxic lipopolysaccharide-binding proteins on murine splenocytes. III. Binding specificity and characterization. J. Immunol. 147:1925.
13. Hampton, R. Y., D. T. Golenbock, M., Penman, M. Krieger, and C. R. H. Raetz. 1991. Recognition and plasma clearance of endotoxin by scavenger receptors. Nature 352:342.
14. Kirikae, T., F. Kirikae, F. U. Schade, M. Yoshida, S. Kondo, K. Hisatsune, S.-I. Nishikawa, and E. Th. Rietschel. 1991. Detection of lipopolysaccharide-binding proteins on membranes of murine lymphocytes and macrophage-like cell lines. FEMS Microbiol. Immunol. 76:327.
15. Kielian, T. L., and F. Blecha. 1995. CD14 and other recognition molecules for lipopolysaccharide: a review. Immunopharmacology 29:187.
16. Wright, S. D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431.
17. Couturier, C., N. Haeffner-Cavaillon, M. Caroff, and M. D. Kazatchkine. 1991. Binding sites for endotoxins (lipopolysaccharides) on human monocytes. J. Immunol. 147:1899.
18. Hailman, E., H. S. Lichtenstein, M. M. Wurfel, D. S. Miller, D. A. Johnson, M. Kelley, L. A. Busse, M. M. Zukowski, and S. D. Wright. 1994. Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14. J. Exp. Med 179:269.
19. Wurfel, M., E. Hailman, and S. D. Wright. 1995. Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein. J. Exp. Med. 181:1743.
20. Metsikkö, K., G. van Meer, and K. Simons. 1986. Reconstitution of the fusogenic activity of vesicular stomatitis virus. EMBO J. 5:3429.
21. Stegmann, T., H. W. M. Morselt, F. P. Booy, J. F. L. van Breemen, G. Scherphof, and J. Wilschut. 1987. Functional reconstitution of influenza virus envelopes. EMBO J. 6:2651.
22. Nussbaum, O., M. Lapidot, and A. Loyter. 1987. Reconstitution of functional influenza virus envelopes and fusion with membranes and liposomes lacking virus receptors. J. Virol. 61:2245.
23. Bron, R., A. Ortiz, J. Dijkstra, T. Stegmann, and J. Wilschut. 1993. Preparation, properties and applications of reconstituted influenza virus envelopes (virosomes). Methods Enzymol. 220:313.
24. Dijkstra, J., J. W. Mellors, J. L. Ryan, and F. C. Szoka. 1987. Modulation of the biological activity of bacterial endotoxin by incorporation into liposomes. J. Immunol. 138:2663.
25. Dijkstra, J., J. W. Larrick, J. L. Ryan, and F. C. Szoka. 1988. Incorporation of LPS in liposomes diminishes its ability to induce tumoricidal activity and tumor necrosis factor secretion in murine macrophages. J. Leukocyte Biol. 43:426.
26. Dijkstra, J., J. W. Mellors, and J. L. Ryan. 1989. Altered in vivo activity of liposome-incorporated lipopolysaccharide and lipid A. Infect. Immun. 57:3357.
27. Peterson, G. L. 1977. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem. 83:346.
28. Bligh, E. G., and W. J. Dyer. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Biophys. 37:911.
29. Böttcher, C. J. F., C. M. van Gent, and C. Fiers. 1961. A rapid and sensitive sub-micro phosphorus determination. Anal. Chim. Acta 24:203.
30. Puri, A., F. P. Booy, R. W. Doms, J. M. White, and R. Blumenthal. 1990. Conformational changes and fusion activity of influenza virus hemagglutin of the H2 and H3 subtypes: effects of acid pretreatment. J. Virol. 64:3824.
31. Dijkstra, J., J. L. Ryan, and F. C. Szoka. 1988. A procedure for the efficient incorporation of wild-type lipopolysaccharide into liposomes for use in immunological studies. J. Immunol. Methods 114:197.
32. Dijkstra, J. 1992. A comparison of methods for the preparation of lipopolysaccharide-containing liposomes. In Liposome Technology, vol. II: Entrapment of Drugs and Other Materials. G. Gregoriadis, ed. CRC Press, Inc., Boca Raton, p. 89.
33. Mayer, L. D., M. J. Hope, and P. R. Cullis. 1986. Vesicles of variable sizes produced by a rapid extrusion procedure. Biochim. Biophys. Acta 858:161.
34. Girl, J. G., P. W. Kincade, and S. B. Mizel. 1984. Interleukin 1-mediated interaction of κ-light chain synthesis and surface immunoglobulin expression on pre-B cells. J. Immunol. 132:223.
35. Ohno, N., and D. C. Morrison. 1989. Lipopolysaccharide interactions with lysozyme differentially affect lipopolysaccharide immunostimulatory activity. Eur. J. Biochem. 186:629.
36. Marsh, M., and A. Helenius. 1989. Virus entry into animal cells. Adv. Virus Res. 36:107.
37. Vogel, S. N., M. L. Hilfiker, and M. J. Caulfield. 1983. Endotoxin induced T-lymphocyte proliferation. J. Immunol. 130:1774.
38. Paige, C. L., P. W. Kincade, and P. Ralph. 1981. Independent control of immunoglobulin heavy and light chain expression in a murine pre-B-cell line. Nature 292:631.
39. Ramalho Santos, J., S. Nir, N. Duzgunes, A. P. De Carvalho, and M. Pedroso De Lima. 1993. A common mechanism for influenza virus fusion activity and inactivation. Biochemistry 32:2771.
40. Dijkstra, J., W. J. M. van Galen, C. E. Hulstaert, D. Kalicharan, F. H. Roerdink, and G. L. Scherphof. 1984. Interaction of liposomes with Kupffer cells in vitro. Exp. Cell Res. 151:161.
41. Machy, P., J. Barbet, and L. D. Leserman. 1982. Differential endocytosis of T and B lymphocyte surface molecules evaluated with antibody-bearing fluorescent liposomes containing methrotrexate. Proc. Natl. Acad. Sci. USA 79:4148.
42. Casali, P., G. P. A. Rice, and M. B. A. Oldstone. 1984. Viruses disrupt functions of human lymphocytes: effects of measles virus and influenza virus on lymphocyte-mediated killing and antibody production. J. Exp. Med. 159:1322.
43. Roberts, N. J., and P. K. Horan. 1985. Expression of viral antigens after infection of human lymphocytes, monocytes, and macrophages with influenza virus. J. Infect. Dis. 151:308.
44. Bona, C., D. Juy, P. Truffa-Bachi, and G. J. Kaplan. 1976. Binding, capping and internalization of lipopolysaccharide in thymic and non-thymic lymphocytes of the mouse: biological and autoradiographic study. J. Microsc. Biol. Cell. 25:47.
45. Luchi, M., and R. S. Munford. 1993. Binding, internalization, and deacylation of bacterial lipopolysaccharide by human neutrophils. J. Immunol. 151:959.
46. Joseph, C. K., S. D. Wright, W. G. Bornmann, J. T. Randolph, E. R. Kumar, R. Bittman, J. Liu, and R. N. Kolesnick. 1994. Bacterial lipopolysaccharide has structural similarity to ceramide and stimulates ceramide-activated protein kinase in myeloid cells. J. Biol. Chem. 269:17606.
47. Wright, S. D., and R. N. Kolesnick. 1995. Does endotoxin stimulate cells by mimicking ceramide? Immunol. Today 16:297.
48. Kolesnick, R., and D. W. Golde. 1994. The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling. Cell 77:325.
49. Kolesnick, R. N., and Z. Fuls. 1995. Ceramide: a signal for apoptosis or mitogenesis? J. Exp. Med. 181:1949.
50. Schütze, S., K. Potthoff, T. Machleidt, D. Berkovic, K. Wiegmann, and M. Krönke. 1992. TNF activates NF-κB by phosphatidylcholine-specific phospholipase C induced "acidic" sphingomyelin breakdown. Cell 71:765.
51. Boucher, L.-M., K. Wiegmann, A. Fütterer, K. Pfeffer, T. Machleidt, S. Schütze, T. W. Mak, and M. Krönke. 1995. CD28 signals through acidic sphingomyelinase. J. Exp. Med. 181:2059.
52. Lynn, W. A., Y. Liu, and D. T. Golenbock. 1993. Neither CD14 nor serum is absolutely necessary for activation of mononuclear phagocytes by bacterial lipopolysaccharide. Infect. Immun. 61:4452.
53. Corrales, I., A. J. L. Weersink, J. Verhoef, and K. P. M. van Kessel. 1993. Serum-independent binding of lipopolysaccharide to human monocytes is trypsin sensitive and does not involve CD14. Immunology 80:84.
54. Couturier, C., G. Jahns, M. D. Kazatchkine, and N. Haeffner-Cavaillon. 1992. Membrane molecules which trigger the production of interleukin-1 and tumor necrosis factor-α by lipopolysaccharide-stimulated human monocyles. Eur. J. Immunol. 22:1461.
55. Takayama, K., Z. Z. Din, P. Mukerjee, P. H. Cooke, and T. N. Kirkland. 1990. Physicochemical properties of the lipopolysaccharide unit that activates B lymphocytes. J. Biol. Chem. 265:14023.
56. Takayama, K., D. H. Mitchell, Z. Z. Din, P. Mukerjee, C. Li, and D. Coleman. 1994. Monomeric Re lipopolysaccharide from Escherichia coli is more active than the aggregated form in the Limulus amebocyte lysate assay and in inducing Egr-1 mRNA in murine peritoneal macrophages. J. Immunol. 269: 2241.
57. Seydel, U., and K. Brandenburg. 1992. Supramolecular structure of lipopolysaccharides and lipid A. In: Bacterial Endotoxic Lipopolysaccharides, Vol. 1: Molecular Biochemistry and Cellular Biology. D. C. Morrison and J. L. Ryan, eds. CRC Press, Boca Raton, p. 225.
58. Wright, S. D. 1995. CD14 and innate recognition of bacteria. J. Immunol. 155:6.
59. Haziot, A., B.-Z. Tsuberi, and S. M. Goyert. 1993. Neutrophil CD14: biochemical properties and role in the secretion of tumor necrosis factor-α in response to lipopolysaccharide. J. Immunol. 150:5556.
60. Frey, E. A., D. S. Miller, T. G. Jahr, A. Sundan, V. Basil, T. Espevik, B. B. Finlay, and S. D. Wright. 1992. Soluble CD14 participates in the response of cells to lipopolysaccharide. J. Exp. Med. 176:1665.
61. Pugin, J., C.-C. Schürer-Maley, D. Leturcq, A. Moriarty, R. J. Ulevitch, and P. Tobias. 1993. Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. Proc. Natl. Acad. Sci. USA 90:2744.
62. Loppnov, H., F. Stelter, U. Schönbeck, C. Schlüter, M. Ernst, C. Schütt, and H.-D. Flad. 1995. Endotoxin activates human vascular smooth muscle cells despite lack of expression of CD14 mRNA or endogenous membrane CD14. Infect. Immun. 63:1020.
63. Lee, J.-D., K. Kato, P. S. Tobias, T. N. Kirkland, and R. J. Ulevitch. 1992. Transfection of CD14 into 70Z/3 cells dramatically enhances the sensitivity to complexes of lipopolysaccharide (LPS) and LPS binding protein. J. Exp. Med. 175:1697.