-
1
-
-
0028183408
-
The molecular basis of X-linked severe combined immunodeficiency: The role of the interleukin-2 receptor γ chain as a common γ chain, γc
-
Leonard WJ, Noguchi M, Russell SM, McBride OW. The molecular basis of X-linked severe combined immunodeficiency: the role of the interleukin-2 receptor γ chain as a common γ chain, γc. Immunolog Rev 1994;138:61-86.
-
(1994)
Immunolog Rev
, vol.138
, pp. 61-86
-
-
Leonard, W.J.1
Noguchi, M.2
Russell, S.M.3
McBride, O.W.4
-
2
-
-
0026691858
-
Molecular approaches to analysis of X-linked immunodeficiencies
-
Conley ME. Molecular approaches to analysis of X-linked immunodeficiencies. Annu Rev Immunol 1992;10:215-38.
-
(1992)
Annu Rev Immunol
, vol.10
, pp. 215-238
-
-
Conley, M.E.1
-
3
-
-
0029924265
-
The molecular basis of X-linked severe combined immunodeficiency: Defective cytokine receptor signaling
-
Leonard WJ. The molecular basis of X-linked severe combined immunodeficiency: defective cytokine receptor signaling. Annu Rev Med 1996;47:229-39.
-
(1996)
Annu Rev Med
, vol.47
, pp. 229-239
-
-
Leonard, W.J.1
-
4
-
-
0027403374
-
Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans
-
Noguchi M, Yi H, Rosenblatt HM, Filipovich AH, Adelstein S, Modi WS, McBride OW, Leonard WJ. Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans. Cell 1993;73:147-57.
-
(1993)
Cell
, vol.73
, pp. 147-157
-
-
Noguchi, M.1
Yi, H.2
Rosenblatt, H.M.3
Filipovich, A.H.4
Adelstein, S.5
Modi, W.S.6
McBride, O.W.7
Leonard, W.J.8
-
5
-
-
0026684134
-
Cloning of the γ chain of the human IL-2 receptor
-
Takeshita T, Asao H, Ohtani K, Ishii N, Kumaki S, Tanaka N, Munakata H, Nakamura M, Sugamura K. Cloning of the γ chain of the human IL-2 receptor. Science 1992;257:379-82.
-
(1992)
Science
, vol.257
, pp. 379-382
-
-
Takeshita, T.1
Asao, H.2
Ohtani, K.3
Ishii, N.4
Kumaki, S.5
Tanaka, N.6
Munakata, H.7
Nakamura, M.8
Sugamura, K.9
-
6
-
-
0025162844
-
Structural design and molecular evolution of a cytokine receptor superfamily
-
Bazan JF. Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci USA 1990;87:6934-8.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 6934-6938
-
-
Bazan, J.F.1
-
7
-
-
0023230069
-
The IL-2 receptor β chain (p70): Role in mediating signals for LAK, NK, and proliferative activities
-
Siegel JP, Sharon M, Smith PL, Leonard WJ. The IL-2 receptor β chain (p70): role in mediating signals for LAK, NK, and proliferative activities. Science 1987;238:75-8.
-
(1987)
Science
, vol.238
, pp. 75-78
-
-
Siegel, J.P.1
Sharon, M.2
Smith, P.L.3
Leonard, W.J.4
-
8
-
-
0028286627
-
Heterodimerization of the IL-2 receptor β- and γ-chain cytoplasmic domains is required for signaling
-
Nakamura Y, Russell SM, Mess SA, Friedmann M, Erdos M, Francois C, Jacques Y, Adelstein S, Leonard WJ. Heterodimerization of the IL-2 receptor β- and γ-chain cytoplasmic domains is required for signaling. Nature 1994;369:330-3.
-
(1994)
Nature
, vol.369
, pp. 330-333
-
-
Nakamura, Y.1
Russell, S.M.2
Mess, S.A.3
Friedmann, M.4
Erdos, M.5
Francois, C.6
Jacques, Y.7
Adelstein, S.8
Leonard, W.J.9
-
9
-
-
0028286628
-
Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation
-
Nelson BH, Lord AD, Greenberg PD. Cytoplasmic domains of the interleukin-2 receptor β and γ chains mediate the signal for T-cell proliferation. Nature 1994;369:333-6.
-
(1994)
Nature
, vol.369
, pp. 333-336
-
-
Nelson, B.H.1
Lord, A.D.2
Greenberg, P.D.3
-
10
-
-
0027379585
-
Characterization of the human interleukin-2 receptor γ chain gene
-
Noguchi M, Adelstein S, Cao X, Leonard WJ. Characterization of the human interleukin-2 receptor γ chain gene. J Biol Chem 1993;268:13601-8.
-
(1993)
J Biol Chem
, vol.268
, pp. 13601-13608
-
-
Noguchi, M.1
Adelstein, S.2
Cao, X.3
Leonard, W.J.4
-
11
-
-
0023442485
-
Close linkage of the locus for X chromosome-linked severe combined immunodeficiency to polymorphic DNA markers in Xq11-Xq13
-
de Saint Basile GD, Arveiler B, Oberle I, Malcolm S, Levinsky RJ, Lau YL, Hofker M, Debre M, Fischer A, Friscelli C, Mandel JL. Close linkage of the locus for X chromosome-linked severe combined immunodeficiency to polymorphic DNA markers in Xq11-Xq13. Proc Natl Acad Sci USA 1987;84:7576-9.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 7576-7579
-
-
De Saint Basile, G.D.1
Arveiler, B.2
Oberle, I.3
Malcolm, S.4
Levinsky, R.J.5
Lau, Y.L.6
Hofker, M.7
Debre, M.8
Fischer, A.9
Friscelli, C.10
Mandel, J.L.11
-
12
-
-
0343046852
-
Recombinant interleukin 2 therapy in severe combined immunodeficiency disease
-
Pahwa R, Chatila T, Pahwa S, Paradise C, Day NK, Geha R, Schwartz SA, Slade H, Oyaizu N, Good RA. Recombinant interleukin 2 therapy in severe combined immunodeficiency disease. Proc Natl Acad Sci USA 1989;86:5069-73.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 5069-5073
-
-
Pahwa, R.1
Chatila, T.2
Pahwa, S.3
Paradise, C.4
Day, N.K.5
Geha, R.6
Schwartz, S.A.7
Slade, H.8
Oyaizu, N.9
Good, R.A.10
-
13
-
-
0025297840
-
Severe combined immunodeficiency due to a specific defect in the production of interleukin-2
-
Weinberg K, Parkman R. Severe combined immunodeficiency due to a specific defect in the production of interleukin-2. N Engl J Med 1990;322:1718-23.
-
(1990)
N Engl J Med
, vol.322
, pp. 1718-1723
-
-
Weinberg, K.1
Parkman, R.2
-
14
-
-
0025899598
-
Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
-
Schorle H, Holtschke T, Hunig T, Schimpl A, Horak I. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting. Nature 1991;352:621-4.
-
(1991)
Nature
, vol.352
, pp. 621-624
-
-
Schorle, H.1
Holtschke, T.2
Hunig, T.3
Schimpl, A.4
Horak, I.5
-
15
-
-
0027320217
-
The interleukin-2 receptor γ chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1
-
Puck JM, Deschenes SM, Porter JC, Dutra AS, Brown CJ, Willard HF, Henthorn PS. The interleukin-2 receptor γ chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1. Human Molec Genet 1993;2:1099-104.
-
(1993)
Human Molec Genet
, vol.2
, pp. 1099-1104
-
-
Puck, J.M.1
Deschenes, S.M.2
Porter, J.C.3
Dutra, A.S.4
Brown, C.J.5
Willard, H.F.6
Henthorn, P.S.7
-
16
-
-
0028009181
-
Interleukin-2 (IL-2) receptor γ chain mutations in X-linked severe combined immunodeficiency disease result in the loss of high-affinity IL-2 receptor binding
-
DiSanto JP, Dautry-Varsat A, Certain S, Fischer A, de Saint Basile G. Interleukin-2 (IL-2) receptor γ chain mutations in X-linked severe combined immunodeficiency disease result in the loss of high-affinity IL-2 receptor binding. Eur J Immunol 1994;24:475-9.
-
(1994)
Eur J Immunol
, vol.24
, pp. 475-479
-
-
DiSanto, J.P.1
Dautry-Varsat, A.2
Certain, S.3
Fischer, A.4
De Saint Basile, G.5
-
17
-
-
0028087777
-
Defective human interleukin-2 receptor γ chain in an atypical X chromosome-linked severe combined immunodeficiency with peripheral T cells
-
DiSanto JP, Rieux-Laucat F, Dautry-Varsat A, Fischer A, de Saint Basile G. Defective human interleukin-2 receptor γ chain in an atypical X chromosome-linked severe combined immunodeficiency with peripheral T cells. Proc Natl Acad Sci USA 1994;91:9466-70.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9466-9470
-
-
DiSanto, J.P.1
Rieux-Laucat, F.2
Dautry-Varsat, A.3
Fischer, A.4
De Saint Basile, G.5
-
18
-
-
0028243660
-
Impairment of ligand binding and growth signaling of mutant IL-2 receptor γ-chains in patients with X-linked severe combined immunodeficiency
-
Ishii N, Asao H, Kimura Y. Impairment of ligand binding and growth signaling of mutant IL-2 receptor γ-chains in patients with X-linked severe combined immunodeficiency. J Immunol 1994;1309-17.
-
(1994)
J Immunol
, pp. 1309-1317
-
-
Ishii, N.1
Asao, H.2
Kimura, Y.3
-
19
-
-
6444233302
-
Unambiguous assignment of carrier status for females in X-linked severe combined immunodeficiency families based on direct mutational analysis
-
Caragol I, Espanol T, Fontan G, Matamores N, editors. Barcelona: Springer-Verlag Iberica
-
Clark PA, Lester T, de Alwis M, Jones A, Kinnon C. Unambiguous assignment of carrier status for females in X-linked severe combined immunodeficiency families based on direct mutational analysis. In: Caragol I, Espanol T, Fontan G, Matamores N, editors. Progress in immune deficiency V. Barcelona: Springer-Verlag Iberica, 1995:139-40.
-
(1995)
Progress in Immune Deficiency V
, pp. 139-140
-
-
Clark, P.A.1
Lester, T.2
De Alwis, M.3
Jones, A.4
Kinnon, C.5
-
20
-
-
0028847795
-
Female germ line mosaicism as the origin of a unique IL-2 receptor γ-chain mutation causing X-linked severe combined immunodeficiency
-
Puck JM, Pepper AE, Bedard P-M, Laframboise R. Female germ line mosaicism as the origin of a unique IL-2 receptor γ-chain mutation causing X-linked severe combined immunodeficiency. J Clin Invest 1995;95:895-9.
-
(1995)
J Clin Invest
, vol.95
, pp. 895-899
-
-
Puck, J.M.1
Pepper, A.E.2
Bedard, P.-M.3
Laframboise, R.4
-
21
-
-
0029161486
-
Two mutational hotspots in the interleukin-2 receptor γ chain gene causing human X-linked severe combined immunodeficiency
-
Pepper AE, Buckley RH, Small TN, Puck JM. Two mutational hotspots in the interleukin-2 receptor γ chain gene causing human X-linked severe combined immunodeficiency. Am J Hum Gen 1995;57:564-71.
-
(1995)
Am J Hum Gen
, vol.57
, pp. 564-571
-
-
Pepper, A.E.1
Buckley, R.H.2
Small, T.N.3
Puck, J.M.4
-
22
-
-
0029161743
-
A retroviral vector for gene therapy of X-linked SCID
-
Qazilbash MH, Walsh CE, Russell SM, Noguchi M, Mann MM, Leonard WJ, Liu JM. A retroviral vector for gene therapy of X-linked SCID. J Hematother 1995;4:91-8.
-
(1995)
J Hematother
, vol.4
, pp. 91-98
-
-
Qazilbash, M.H.1
Walsh, C.E.2
Russell, S.M.3
Noguchi, M.4
Mann, M.M.5
Leonard, W.J.6
Liu, J.M.7
-
23
-
-
0030008035
-
Retroviral-mediated gene correction for X-linked severe combined immunodeficiency
-
Candotti F, Johnston JA, Puck JM, Sugamura K, O'Shea JJ, Blaese RM. Retroviral-mediated gene correction for X-linked severe combined immunodeficiency. Blood 1996;87:3097-102.
-
(1996)
Blood
, vol.87
, pp. 3097-3102
-
-
Candotti, F.1
Johnston, J.A.2
Puck, J.M.3
Sugamura, K.4
O'Shea, J.J.5
Blaese, R.M.6
-
25
-
-
15844426339
-
c gene transfer into SCID XI patients' B-cell lines restores normal high-affinity interleukin-2 receptor expression and function
-
c gene transfer into SCID XI patients' B-cell lines restores normal high-affinity interleukin-2 receptor expression and function. Blood 1996;87:3108-16.
-
(1996)
Blood
, vol.87
, pp. 3108-3116
-
-
Hacein-Bey, S.1
Cavazzana-Calvo, M.2
Le Deist, F.3
Dautry-Varsat, A.4
Hivroz, C.5
Riviere, I.6
Danos, O.7
Heard, J.M.8
Sugamura, K.9
Fischer, A.10
De Saint Basile, G.11
-
26
-
-
0026689408
-
Cytokine receptors and signal transduction
-
Miyajima A, Kitamura T, Harada N, Yokota T, Arai K. Cytokine receptors and signal transduction. Annu Rev Immunol 1992;10:295-331.
-
(1992)
Annu Rev Immunol
, vol.10
, pp. 295-331
-
-
Miyajima, A.1
Kitamura, T.2
Harada, N.3
Yokota, T.4
Arai, K.5
-
27
-
-
0028946686
-
Signaling mechanisms through cytokine receptors that share signal transducing receptor components
-
Taga T, Kishimoto T. Signaling mechanisms through cytokine receptors that share signal transducing receptor components. Curr Opin Immunol 1995;7:17-23.
-
(1995)
Curr Opin Immunol
, vol.7
, pp. 17-23
-
-
Taga, T.1
Kishimoto, T.2
-
28
-
-
0028905072
-
Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex
-
Pennica D, Shaw KJ, Swanson TA, Moore MW, Shelton DL, Zioncheck KA, Rosenthal A, Taga T, Paoni NF, Wood WI, Goeddel D. Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex. J Biol Chem 1995;270:10915-22.
-
(1995)
J Biol Chem
, vol.270
, pp. 10915-10922
-
-
Pennica, D.1
Shaw, K.J.2
Swanson, T.A.3
Moore, M.W.4
Shelton, D.L.5
Zioncheck, K.A.6
Rosenthal, A.7
Taga, T.8
Paoni, N.F.9
Wood, W.I.10
Goeddel, D.11
-
29
-
-
0027787877
-
Interleukin-2 receptor γ chain: A functional component of the interleukin-4 receptor
-
Russell SM, Keegan AD, Harada N, Nakamura Y, Noguchi M, Leland P, Friedmann MC, Miyajima A, Puri RK, Paul WE, Leonard WJ. Interleukin-2 receptor γ chain: a functional component of the interleukin-4 receptor. Science 1993;262:1880-3.
-
(1993)
Science
, vol.262
, pp. 1880-1883
-
-
Russell, S.M.1
Keegan, A.D.2
Harada, N.3
Nakamura, Y.4
Noguchi, M.5
Leland, P.6
Friedmann, M.C.7
Miyajima, A.8
Puri, R.K.9
Paul, W.E.10
Leonard, W.J.11
-
30
-
-
0027751556
-
Interleukin-2 receptor γ chain: A functional component of the interleukin-7 receptor
-
Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ. Interleukin-2 receptor γ chain: a functional component of the interleukin-7 receptor. Science 1993;262:1877-80.
-
(1993)
Science
, vol.262
, pp. 1877-1880
-
-
Noguchi, M.1
Nakamura, Y.2
Russell, S.M.3
Ziegler, S.F.4
Tsang, M.5
Cao, X.6
Leonard, W.J.7
-
31
-
-
0027731604
-
Sharing of the interleukin-2 receptor γ chain between receptors for IL-2 and IL-4
-
Kondo M, Takeshita T, Ishii N, Nakamura M, Watanabe S, Arai K, Sugamura K. Sharing of the interleukin-2 receptor γ chain between receptors for IL-2 and IL-4. Science 1993;262:1874-7.
-
(1993)
Science
, vol.262
, pp. 1874-1877
-
-
Kondo, M.1
Takeshita, T.2
Ishii, N.3
Nakamura, M.4
Watanabe, S.5
Arai, K.6
Sugamura, K.7
-
32
-
-
0028327550
-
Functional participation of the IL-2 receptor γ chain in IL-7 receptor complexes
-
Kondo M, Takeshita T, Higuchi M, Nakamura M, Sudo T, Nishikawa S-I, Sugamura K. Functional participation of the IL-2 receptor γ chain in IL-7 receptor complexes. Science 1994;364:1453-4.
-
(1994)
Science
, vol.364
, pp. 1453-1454
-
-
Kondo, M.1
Takeshita, T.2
Higuchi, M.3
Nakamura, M.4
Sudo, T.5
Nishikawa, S.-I.6
Sugamura, K.7
-
33
-
-
0028171065
-
c chains with Jak1 and Jak3: Implications for XSCID and XCID
-
c chains with Jak1 and Jak3: Implications for XSCID and XCID. Science 1994;266:1042-5.
-
(1994)
Science
, vol.266
, pp. 1042-1045
-
-
Russell, S.M.1
Johnston, J.A.2
Noguchi, M.3
Kawamura, M.4
Bacon, C.M.5
Friedmann, M.6
Berg, M.7
McVicar, D.W.8
Witthuhn, B.A.9
Silvennoinen, O.10
Goldman, A.S.11
Schmalstieg, F.C.12
Ihle, J.N.13
O'Shea, J.J.14
Leonard, W.J.15
-
34
-
-
0028814556
-
Sharing of the IL-2 receptor γ chain with the functional IL-9 receptor complex
-
Kimura M, Ishii N, Nakamura M, Van Snick J, Sugamura K. Sharing of the IL-2 receptor γ chain with the functional IL-9 receptor complex. Int Immunol 1995;7:115-20.
-
(1995)
Int Immunol
, vol.7
, pp. 115-120
-
-
Kimura, M.1
Ishii, N.2
Nakamura, M.3
Van Snick, J.4
Sugamura, K.5
-
35
-
-
0028221433
-
Utilization of the β and γ chains of the IL-2 receptor by the novel cy;okine IL-15
-
Giri JG, Ahdieh M, Eisenman J, Shanebeck K, Grabstein K, Kumatki S, Namen A, Park LS, Cosman D, Anderson D. Utilization of the β and γ chains of the IL-2 receptor by the novel cy;okine IL-15. EMBO J 1994;13:2822-30.
-
(1994)
EMBO J
, vol.13
, pp. 2822-2830
-
-
Giri, J.G.1
Ahdieh, M.2
Eisenman, J.3
Shanebeck, K.4
Grabstein, K.5
Kumatki, S.6
Namen, A.7
Park, L.S.8
Cosman, D.9
Anderson, D.10
-
36
-
-
0027969342
-
The defective gene in X-linked severe combined immunodeficiency encodes a shared interleukin receptor subunit: Implications for cytokine pleiotropy and redundancy
-
Leonard WJ. The defective gene in X-linked severe combined immunodeficiency encodes a shared interleukin receptor subunit: implications for cytokine pleiotropy and redundancy. Curr Opin Immunol 1994;6:631-5.
-
(1994)
Curr Opin Immunol
, vol.6
, pp. 631-635
-
-
Leonard, W.J.1
-
37
-
-
0029069145
-
Transcriptional responses to polypeptide ligands: The JAK-STAT pathway
-
Schindler C, Darnell JE Jr. Transcriptional responses to polypeptide ligands: the JAK-STAT pathway. Annu Rev Biochem 1995;64:621-51.
-
(1995)
Annu Rev Biochem
, vol.64
, pp. 621-651
-
-
Schindler, C.1
Darnell Jr., J.E.2
-
38
-
-
0028339282
-
Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2
-
Johnston A, Kawamura M, Kirken RA, Chen YQ, Blake TB, Shibuya K, Ortaldo JR, McVicar DW, O'Shea JJ. Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2. Nature 1994;370:151-3.
-
(1994)
Nature
, vol.370
, pp. 151-153
-
-
Johnston, A.1
Kawamura, M.2
Kirken, R.A.3
Chen, Y.Q.4
Blake, T.B.5
Shibuya, K.6
Ortaldo, J.R.7
McVicar, D.W.8
O'Shea, J.J.9
-
39
-
-
0028244396
-
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells
-
Witthuhn BA, Silvennoinen O, Miura O, Lai KS, Cwik C, Liu ET, Ihle JN. Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells. Nature 1994;370:153-7.
-
(1994)
Nature
, vol.370
, pp. 153-157
-
-
Witthuhn, B.A.1
Silvennoinen, O.2
Miura, O.3
Lai, K.S.4
Cwik, C.5
Liu, E.T.6
Ihle, J.N.7
-
40
-
-
0028114542
-
c chain of the IL-2 receptor
-
c chain of the IL-2 receptor. Science 1994;266:1039-42.
-
(1994)
Science
, vol.266
, pp. 1039-1042
-
-
Boussiotis, V.A.1
Barber, D.L.2
Nakarai, T.3
Freeman, G.J.4
Gribben, J.G.5
Bernstein, G.M.6
D'Andrea, A.D.7
Ritz, J.8
Nadler, L.M.9
-
41
-
-
0027993022
-
Functional activation of Jak1 and Jak3 by selective: Association with IL-2 receptor subunits
-
Miyazaki T, Kawahara A, Fujii H, Nakagawa Y, Minami Y, Liu Z-J, Oishi I, Silvennoinen O, Witthuhn BA, Ihle JN, Taniguchi T. Functional activation of Jak1 and Jak3 by selective: association with IL-2 receptor subunits. Science 1994;266:1045-7.
-
(1994)
Science
, vol.266
, pp. 1045-1047
-
-
Miyazaki, T.1
Kawahara, A.2
Fujii, H.3
Nakagawa, Y.4
Minami, Y.5
Liu, Z.-J.6
Oishi, I.7
Silvennoinen, O.8
Witthuhn, B.A.9
Ihle, J.N.10
Taniguchi, T.11
-
42
-
-
0028919560
-
Missense mutation in exon 7 of the common γ chain gene causes a moderate form of X-linked combined immunodeficiency
-
Schmalstieg FC, Leonard WJ, Noguchi M, Berg M, Rudioff HE, Denney RM, Dave SK, Brooks EG, Goldman AS. Missense mutation in exon 7 of the common γ chain gene causes a moderate form of X-linked combined immunodeficiency. J Clin Invest 1995;95:1169-73.
-
(1995)
J Clin Invest
, vol.95
, pp. 1169-1173
-
-
Schmalstieg, F.C.1
Leonard, W.J.2
Noguchi, M.3
Berg, M.4
Rudioff, H.E.5
Denney, R.M.6
Dave, S.K.7
Brooks, E.G.8
Goldman, A.S.9
-
43
-
-
0028857954
-
Mutation of Jak3 in a patient with SCID: Essential role of Jak3 in lymphoid development
-
Russell SM, Tayebi N, Nakajima H, Riedy MC, Robert JL, Aman MJ, Migone T-S, Noguchi M, Markert ML, Buckley RH, O'Shea JJ, Leonard WJ. Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. Science 1995;270:797-800.
-
(1995)
Science
, vol.270
, pp. 797-800
-
-
Russell, S.M.1
Tayebi, N.2
Nakajima, H.3
Riedy, M.C.4
Robert, J.L.5
Aman, M.J.6
Migone, T.-S.7
Noguchi, M.8
Markert, M.L.9
Buckley, R.H.10
O'Shea, J.J.11
Leonard, W.J.12
-
44
-
-
0029164841
-
Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)
-
Macchi P, Villa A, Gillani S, Sacco MG, Frattini A, Porta F, Ugazio AG, Johnston JA, Candotti F, O'Shea JJ, Vezzoni P, Notarangelo LD. Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID). Nature 1995;377:65-8.
-
(1995)
Nature
, vol.377
, pp. 65-68
-
-
Macchi, P.1
Villa, A.2
Gillani, S.3
Sacco, M.G.4
Frattini, A.5
Porta, F.6
Ugazio, A.G.7
Johnston, J.A.8
Candotti, F.9
O'Shea, J.J.10
Vezzoni, P.11
Notarangelo, L.D.12
-
45
-
-
0029115353
-
Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction
-
Kawahara A, Minami Y, Miyazaki T, Ihle JN, Taniguchi T. Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction. Proc Natl Acad Sci USA 1995;92:8724-8.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8724-8728
-
-
Kawahara, A.1
Minami, Y.2
Miyazaki, T.3
Ihle, J.N.4
Taniguchi, T.5
-
46
-
-
0027972046
-
An interleukin-4-induced transcription factor: IL-4 Stat
-
Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M, McKnight SL. An interleukin-4-induced transcription factor: IL-4 Stat. Science 1994;265:1701-6.
-
(1994)
Science
, vol.265
, pp. 1701-1706
-
-
Hou, J.1
Schindler, U.2
Henzel, W.J.3
Ho, T.C.4
Brasseur, M.5
McKnight, S.L.6
-
47
-
-
0028962572
-
The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, H-7, IL-13, and IL-15
-
Lin J-X, Migone T-S, Tsang M, Friedmann M, Weatherbee JA, Zhou L, Yamauchi A, Bloom ET, Mietz J, John S, Leonard WJ. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, H-7, IL-13, and IL-15. Immunity 1995;2:331-9.
-
(1995)
Immunity
, vol.2
, pp. 331-339
-
-
Lin, J.-X.1
Migone, T.-S.2
Tsang, M.3
Friedmann, M.4
Weatherbee, J.A.5
Zhou, L.6
Yamauchi, A.7
Bloom, E.T.8
Mietz, J.9
John, S.10
Leonard, W.J.11
-
48
-
-
0028175454
-
Ligand-induced IFN-γ receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91)
-
Greenlund A, Farrar M, Viviano BL, Schreiber R. Ligand-induced IFN-γ receptor tyrosine phosphorylation couples the receptor to its signal transduction system (p91). EMBO J 1995;13:1591-600.
-
(1995)
EMBO J
, vol.13
, pp. 1591-1600
-
-
Greenlund, A.1
Farrar, M.2
Viviano, B.L.3
Schreiber, R.4
-
49
-
-
0029875230
-
Different interleukin 2 receptor β-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation
-
Friedmann MC, Migone T-S, Russell SM, Leonard WJ. Different interleukin 2 receptor β-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation. Proc Natl Acad Sci USA 1996;93:2077-82.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 2077-2082
-
-
Friedmann, M.C.1
Migone, T.-S.2
Russell, S.M.3
Leonard, W.J.4
-
50
-
-
0027988545
-
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
-
Peschon J, Morrissey PJ, Grabstein KH, Ramsdell FJ, Maraskovsky E, Gliniak BC, Park LS, Ziegler SF, Williams DE, Ware CB, Meyer JD, Davison BL. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med 1994;180:1955-60.
-
(1994)
J Exp Med
, vol.180
, pp. 1955-1960
-
-
Peschon, J.1
Morrissey, P.J.2
Grabstein, K.H.3
Ramsdell, F.J.4
Maraskovsky, E.5
Gliniak, B.C.6
Park, L.S.7
Ziegler, S.F.8
Williams, D.E.9
Ware, C.B.10
Meyer, J.D.11
Davison, B.L.12
-
51
-
-
0028929565
-
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
-
von Freeden-Jeffry U, Vieira P, Lucian LA, McNeil T, Burdach SE, Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med 1995;181:1519-26.
-
(1995)
J Exp Med
, vol.181
, pp. 1519-1526
-
-
Von Freeden-Jeffry, U.1
Vieira, P.2
Lucian, L.A.3
McNeil, T.4
Burdach, S.E.5
Murray, R.6
-
52
-
-
0029005549
-
Constitutively activation Jak-STAT pathway in T cells transformed with HTLV-I
-
Migone T-S, Lin J-X, Cereseto A, Mulloy JC, O'Shea JJ, Franchini G, Leonard WJ. Constitutively activation Jak-STAT pathway in T cells transformed with HTLV-I. Science 1995;269:79-81.
-
(1995)
Science
, vol.269
, pp. 79-81
-
-
Migone, T.-S.1
Lin, J.-X.2
Cereseto, A.3
Mulloy, J.C.4
O'Shea, J.J.5
Franchini, G.6
Leonard, W.J.7
-
53
-
-
0028817880
-
Jak-STAT signaling induced by the v-abl oncogene
-
Danial NN, Pernis A, Rothman PB. Jak-STAT signaling induced by the v-abl oncogene. Science 1995;260:1875-7.
-
(1995)
Science
, vol.260
, pp. 1875-1877
-
-
Danial, N.N.1
Pernis, A.2
Rothman, P.B.3
-
54
-
-
0028915936
-
Induction of sequence-specific DNA-binding factors by erythropoietin and the spleen focus-forming virus
-
Ohashi T, Masuda M, Ruscetti SK. Induction of sequence-specific DNA-binding factors by erythropoietin and the spleen focus-forming virus. Blood 1995;84:1454-62.
-
(1995)
Blood
, vol.84
, pp. 1454-1462
-
-
Ohashi, T.1
Masuda, M.2
Ruscetti, S.K.3
-
55
-
-
0029031668
-
Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects
-
Harrison DA, Binari R, Nahreini TS, Gilman M, Perrimon N. Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO J 1995;14:2857-65.
-
(1995)
EMBO J
, vol.14
, pp. 2857-2865
-
-
Harrison, D.A.1
Binari, R.2
Nahreini, T.S.3
Gilman, M.4
Perrimon, N.5
-
56
-
-
13344295097
-
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
-
Meydan N, Grunberg T, Dadi H, Shahar M, Arpaia E, Lapidot Z, Leeder JS, Freedman M, Cohen A, Gazit A, Levitzki A, Roifman CM. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature 1995;379:645-8.
-
(1995)
Nature
, vol.379
, pp. 645-648
-
-
Meydan, N.1
Grunberg, T.2
Dadi, H.3
Shahar, M.4
Arpaia, E.5
Lapidot, Z.6
Leeder, J.S.7
Freedman, M.8
Cohen, A.9
Gazit, A.10
Levitzki, A.11
Roifman, C.M.12
-
57
-
-
0028169394
-
IL-2Rγ gene microdeletion demonstrates that canine X-linked severe combined immunodeficiency is a homologue of the human disease
-
Henthorn PS, Somberg RL, Fimiana VM, Puck JM, Patterson DF, Felsburg PJ. IL-2Rγ gene microdeletion demonstrates that canine X-linked severe combined immunodeficiency is a homologue of the human disease. Genomics 1994;23:69-74.
-
(1994)
Genomics
, vol.23
, pp. 69-74
-
-
Henthorn, P.S.1
Somberg, R.L.2
Fimiana, V.M.3
Puck, J.M.4
Patterson, D.F.5
Felsburg, P.J.6
-
58
-
-
0028878330
-
Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain
-
DiSanto JP, Muller W, Guy-Grand D, Fischer A, Rajewsky K. Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor γ chain. Proc Natl Acad Sci USA 1995;92:377-81.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 377-381
-
-
DiSanto, J.P.1
Muller, W.2
Guy-Grand, D.3
Fischer, A.4
Rajewsky, K.5
-
59
-
-
0028925778
-
Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain
-
Cao X, Shores EW, Hu-Li J, Anver M, Kelsall BL, Russell SM, Drago J, Noguchi M, Grinberg A, Bloom ET, Paul WE, Katz SI, Love PE, Leonard WJ. Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain. Immunity 1995;2:223-38.
-
(1995)
Immunity
, vol.2
, pp. 223-238
-
-
Cao, X.1
Shores, E.W.2
Hu-Li, J.3
Anver, M.4
Kelsall, B.L.5
Russell, S.M.6
Drago, J.7
Noguchi, M.8
Grinberg, A.9
Bloom, E.T.10
Paul, W.E.11
Katz, S.I.12
Love, P.E.13
Leonard, W.J.14
-
60
-
-
0028799457
-
Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3
-
Thomis DC, Gurniak CB, Tivol E, Sharpe AH, Berg LJ. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science 1995;270:794-7.
-
(1995)
Science
, vol.270
, pp. 794-797
-
-
Thomis, D.C.1
Gurniak, C.B.2
Tivol, E.3
Sharpe, A.H.4
Berg, L.J.5
-
61
-
-
0028840706
-
Defective lymphoid development in mice lacking Jak3
-
Nosaka T, van Deursen JMA, Tripp RA, Thierfelder WE, Witthuhn BA, McMickle AP, Doherty PC, Grosveld GC, Ihle JN. Defective lymphoid development in mice lacking Jak3. Science 1995;270:800-2.
-
(1995)
Science
, vol.270
, pp. 800-802
-
-
Nosaka, T.1
Van Deursen, J.M.A.2
Tripp, R.A.3
Thierfelder, W.E.4
Witthuhn, B.A.5
McMickle, A.P.6
Doherty, P.C.7
Grosveld, G.C.8
Ihle, J.N.9
-
62
-
-
0029550822
-
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice
-
Park SY, Saijo K, Takahash T, Osawa M, Arase H, Hirayama N, Miyake K, Nakauchi H, Shirasawa T, Saito T. Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity 1995;3:771-82.
-
(1995)
Immunity
, vol.3
, pp. 771-782
-
-
Park, S.Y.1
Saijo, K.2
Takahash, T.3
Osawa, M.4
Arase, H.5
Hirayama, N.6
Miyake, K.7
Nakauchi, H.8
Shirasawa, T.9
Saito, T.10
-
63
-
-
0028779529
-
Cytokine receptors in congenital hematopoietic disease
-
d'Andrea AD. Cytokine receptors in congenital hematopoietic disease. N Engl J Med 1994;330:839-46.
-
(1994)
N Engl J Med
, vol.330
, pp. 839-846
-
-
D'Andrea, A.D.1
-
64
-
-
0027215519
-
Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis
-
de la Chapelle A, Traskelin AL, Juvonen E. Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis. Proc Natl Acad Sci USA 1993;90:4495-9.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4495-4499
-
-
De La Chapelle, A.1
Traskelin, A.L.2
Juvonen, E.3
-
65
-
-
0024456661
-
Laron dwarfism and mutations of the growth hormone receptor gene
-
Amselem S, Duquesnoy P, Attree O, Novelli G, Bousnina S, Postel-Vinay MC, Goossens M. Laron dwarfism and mutations of the growth hormone receptor gene. N Engl J Med 1989;321:989-95.
-
(1989)
N Engl J Med
, vol.321
, pp. 989-995
-
-
Amselem, S.1
Duquesnoy, P.2
Attree, O.3
Novelli, G.4
Bousnina, S.5
Postel-Vinay, M.C.6
Goossens, M.7
-
66
-
-
0028328265
-
Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia
-
Dong F, Hoefsloot LH, Schelen AM, Breeders CA, Meijer Y, Veerman AJ, Touw IP, Lowenberg B. Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia. Proc Natl Acad Sci USA 1994;91:4480-4.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4480-4484
-
-
Dong, F.1
Hoefsloot, L.H.2
Schelen, A.M.3
Breeders, C.A.4
Meijer, Y.5
Veerman, A.J.6
Touw, I.P.7
Lowenberg, B.8
|