Production and characteristics of an infusible oxygen-carrying fluid based on hemoglobin intramolecularly cross-linked with sebacic acid

Journal of Laboratory and Clinical Medicine

Volumn 128, Issue 2, 1996, Pages 146-153

  Bucci, Enrico ^a   Razynska, Anna ^b   Kwansa, Herman ^b   Matheson Urbaitis, Barbara ^b   O'Hearne, Michael ^b   Ulatowski, John A ^b   Koehler, Raymond C ^b  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0030205132     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2143(96)90006-2     Document Type: Article

References (12)

1. Eleventh Congress of the International Society for Artificial Cells, Blood Substitutes, and Immobilization Biotechnology. Boston, Massachusetts, 1994.
2. Chatterjee R, Welty E, Walder R, Pruitt S, Rogers P, Arnone A, et al. Isolation and characterization of a new hemoglobin derivative cross-linked between the α-chains (lysine 99α1 and lysine 99α2) J Biol Chem 1986;261:9929-37.
3. Bucci E, Razynska A, Kwansa H, Gryczynski Z, Collins JH, Fronticelli C, et al. Positive and negative cooperativities at subsequent steps of oxygenation regulate the allosteric behavior of multistate sebacylhemoglobin. Biochemistry 1996; 35:3418-25.
4. Wyman J, Gill SJ. Binding and linkage. Mill Valley, CA: University Science Books, 1990.
5. Urbaitis B, Razynska A, Corteza Q, Fronticelli C, Bucci E. Intravascular retention and renal handling of purified natural and intramolecularly cross-linked hemoglobins. J Lab Clin Med 1991;117:115-21.
6. Ulatowski JA, Koehler RC, Nishikawa T, Traystman RJ, Razynska A, Kwansa H, et al. Role of nitric oxide scavenging in peripheral vasoconstrictor response to ββ cross-linked hemoglobin. Biomat Artif Cells Blood Substit Immobil Biotechnol 1995;23:263-9.
7. Keipert PE, Gomez CL, Gonzales A, MacDonald VW, Winslow RM. The role of kidneys in the excretion of chemically modified hemoglobins. Biomat Artif Cell Blood Substit Immobil Biotechnol 1992;20:737-45
8. Hsia JC, Song DL, Er SS, Wong LT, Keipert PE, Gomez CL, et al. Pharmacokinetic studies in the rat on an o-raffinose polymerized human hemoglobin. Biomat Artif Cell Blood Substit Immobil Biotechnol 1992;20:587-95.
9. Hess JS, Fadare L, Tolentino L, Bengal N. The intravascular persistence of DBBF-hemoglobin. Symposium on oxygen binding proteins: structure, dynamics, function and genetics. Pacific Grove, CA: Univesity of New Mexico, 1988.
10. Ulatowski JA, Nishikawa T, Matheson-Urbaitis B, Bucci E, Traystman RJ, Koehler RC. Regional blood flow alterations after bovine fumaryl ββ-cross-linked transfusion and nitric oxide synthase inhibition. Crit Care Med 1996;24:558-65.
11. Chiancone E, Fronticelli C, Gattoni M, Urbaitis B, Bucci E. Immobilized hemoglobin in the purification of hemoglobin-based oxygen carriers. J Chromatogr 1992;604:117-23.
12. Farmer M, Ebeling A, Marshall T, Hauck W, Sun CS, White E, et al. Validation of virus inactivation by heat treatment in the manufacture of diaspirin cross-linked hemoglobin. Biomat Artif Cell Blood Substit Immobil Biotech 1992;20:429-33.