Is the phenytoin-enteral feeding formula interaction a myth?

Nutrition in Clinical Practice

Volumn 11, Issue 4, 1996, Pages 175-176

  Bertino Jr , Joseph S ^a   Naderer, Odin ^a  

^a Bassett Healthcare Cooperstown   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; PHENYTOIN;

ENTERIC FEEDING; FOOD DRUG INTERACTION; HUMAN; METHODOLOGY; NOTE; TIME;

ANTICONVULSANTS; ENTERAL NUTRITION; FOOD-DRUG INTERACTIONS; HUMANS; PHENYTOIN; RESEARCH DESIGN; TIME FACTORS;

EID: 0030203087     PISSN: 08845336     EISSN: 19412452     Source Type: Journal    
DOI: 10.1177/0115426596011004175     Document Type: Letter

References (7)

1. Gilbert S., Hatton J., Magnuson B. How to minimize interaction between phenytoin and enteral feedings: Two approaches. NCP 1996;11:28-31.
2. Bauer LA Interference of oral phenytoin absorptionbycontinuous nasogastric feedings. Neurology 1982;32:570-2.
3. Chen ML, Patnaik R. Statistical procedures for bioequivalence studies using a standard two-treatment crossover design. Food and Drug Administration Division of Bioequivalence, 9. Food and Drug Administration. Washington, DC, 1992.
4. Krueger KA, Garnett WR, Comstock TJet al.Effect of two administration schedules of an enteral nutrient formula on phenytoinbioavailability. Epilepsia 1987;28:706-12.
5. Marvel ME, Bertino JS Jr. Comparative effects of an elemental and a complex enteral feeding formulation on the absorption of phenytoin suspension. JPEN 1991;15:316-8.
6. Woodbury DM Antiepileptic Drugs, 3rd ed, Levy RH, Dreifuss FE, Mattson RHet al(eds). New York, Raven Press, 1989.
7. Kirby DF, Delegge MH, Fleming CR American Gastroenterological Association technical review on tube feeding for enteral nutrition. Gastroenterology 1995:108:1282-301.