Discovery of a herbicidal lead using polymer-bound activated esters in generating a combinatorial library of amides and esters

Molecular Diversity

Volumn 1, Issue 4, 1996, Pages 266-269

  Parlow, John J ^a   Normansell, Jean E ^a  

^a MONSANTO COMPANY   (United States)

Author keywords

Amide library; Combinatorial library; Ester library; Herbicide lead; Polymer bound activated esters

Indexed keywords

AMIDE; ESTER; HERBICIDE; POLYMER;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DIRECTED MOLECULAR EVOLUTION; DRUG SCREENING; MASS FRAGMENTOGRAPHY; METHODOLOGY; SYNTHESIS;

AMIDES; DIRECTED MOLECULAR EVOLUTION; DRUG EVALUATION, PRECLINICAL; ESTERS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HERBICIDES; MOLECULAR STRUCTURE; POLYMERS;

EID: 0030202284     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01715531     Document Type: Article

References (18)

1. For recent reviews see: a. Ellman, J.A. Thompson, L.A., Chem. Rev., 96 (1996) 555-600.
2. b. Doyle, P.M., J. Chem. Technol. Biotechnol., 64 (1995) 317-324.
3. c. Terrett, N.K., Gardner, M., Gordon, D.W., Kobylecki, R.J. John Steele, J., Tetrahedron, 51 (1995) 8135-8173.
4. d. Gordon, L., Chem. Soc. Rev., 24 (1995) 309-317.
5. e. Doyle, P.M., J. Chem. Technol. Biotechnol., 64 (1995) 317-24.
6. f. Harris, J.C., Biol. Immunol., (1995) 469-476.
7. Smith, P.W., Lai, J.Y.Q., Whittington, A.R., Cox, B., Houston, J.G., Stylli, C.H., Banks, M.N. Tiller, PR., Bioorg. Med. Chem. Lett., 4 (1994) 2821-2824.
8. a. Patchornik, A. Cohen, B.J., In Eberle. A., Wieland, T. Geiger, B. (Eds) Perspectives in Peptide Chemistry, Karger, Basel, Switzerland, 1980, pp. 118-128.
9. b. Fridkin, M., In Gross, E. Meienhofer, J. (Eds) The Peptides, Academic Press, New York, NY, 1980, pp. 333-363.
10. Cohen, B.J., Karoly-Hafeli, H. Patchornik, A., J. Org. Chem., 49 (1984) 922-924.
11. Parlow, J.J., Woodard, S.S., Mischke, D.A. Normansell, J.E., U.S. Patent Application 08/623,4444.
12. a. Sanemitsu, Y, Kawamura, S. Hamada, T., J. Agricult. Food Chem., 39 (1991) 2279-2281.
13. b. Hatanaka, M., Watanabe, J., Kondo, Y, Suzuki, K., Nawa-maki, T. Watanabe, S., Japanese Patent 2-53775, 1990.
14. c. Ishii, S., Yagi, k., Umehara, T., Kudoh, M., Mawamaki, T. Watanabe, S., Japanese Patent 2-129171, 1990.
15. a. Zuckermann, R.N., Martin, E.J., Spellmeyer, D.C., Stauber, G.B., Shoemaker, K.R., Kerr, J.M., Gigliozzi, G.M., Goff, D.A., Siani, M.A., Simon, R.J., Banville, S.C., Brown, E.G., Wang, L., Richter, L.S. Moos, W.H., J. Med. Chem., 37 (1994) 2678-2685.
16. b. Jiracek, J., Yiotakis, A., Vincent, B., Lecoq, A., Nicolaou, A., Checler, F. Dive, V., J. Biol. Chem., 270 (1995) 21701-21706.
17. c. Lutzke, R.A.P., Eppens, N.A., Weber, P.A., Houghten, R.A. Plasterk, R.H.A., Proc. Natl. Acad. Sci. USA, 92 (1995) 11456-11460.
18. d. Pirrung, M.C., Chau, J.H.-L. Chen, J., Chem. Biol., 2 (1995) 621-626.