Solute affinity in ion-exchange displacement chromatography

Chemical Engineering Science

Volumn 51, Issue 15, 1996, Pages 3847-3860

  Brooks, Clayton A ^a,b   Cramer, Steven M ^a  

^a Rensselaer Polytechnic Institute   (United States)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHY; ION EXCHANGE;

AFFINITY CHROMATOGRAPHY; MATHEMATICAL MODELS; PARAMETER ESTIMATION; REACTION KINETICS;

ION EXCHANGE CHROMATOGRAPHY; ION EXCHANGE DISPLACEMENT SYSTEMS; SOLUTE AFFINITY;

ION EXCHANGE;

EID: 0030201449     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-2509(95)00287-1     Document Type: Article

References (31)

1. Berninger, J. A., Whitley, R. D., Zhang, X. and Wang, N. H. L., 1991, A versatile model for simulation of reaction and nonequlibrium dynamics in multicomponent fixed-bed adsorption processes. Comput. Chem. Engng 15, 749-767.
2. Brooks, C. A., 1993, On the characterization of equilibrium in ion-exchange chromatography: steric mass-action ion-exchange. Dissertation, Rensselaer Polytechnic Institute, Troy, NY.
3. Brooks, C. A. and Cramer, S. M., 1992, Steric mass-action ion-exchange: displacement profiles and induced salt gradients. A.I.Ch.E. J. 38, 1969-1978.
4. Cramer, S. M. and Brooks, C. A., 1993, Ion-exchange displacement chromatograpy of proteins: theoretical and experimental studies, In Chromatography in Biotechnology (Edited by Horvath, C. and Ettre, L. S.), ACS Symposium Series 529. ACS, New York.
5. Cramer, S. M. and Jayaraman, G., 1993, Preparative chromatography in biotechnology. Current Opinions Biotechnol., 4, 217-225.
6. Cramer, S. M. and Subramanian, G., 1989, Preparative liquid chromatography of biomolecules-new directions, In New Directions in Sorption Technology (Edited by Keller, E. G. and Yang, R. T.). Butterworths, Stoneham, UK.
7. Cramer, S. M. and Subramanian, G. 1990, Recent advances in the theory and practice of displacement chromatography. Sep. Purif. Methods 19, 31-91.
8. Felinger, A. and Guiochon, G., 1993, Comparison of maximum production rates and optimum operating/design parameters in overloaded elution and displacement chromatography. Biotechnol. Bioengng 41, 134-147.
9. Finleyson, B. A., 1980, Nonlinear Analysis in Chemical Engineering. McGraw-Hill, New York.
10. Frenz, J. and Horváth, Cs., 1985, High performance displacement chromatography: calculation and experimental verification of zone development. A.I.Ch.E. J. 31, 400-409.
11. Frenz, J. and Horváth, Cs., 1988, High performance displacement chromatography, In High Performance Liquid Chromatography, Advances and Perspectives, Vol. 5 (Edited by Horváth, Cs.). Academic Press, San Diego.
12. Gadam, S. D., Jayaraman, G. and Cramer, S. M., 1993, Characterization of non-linear adsorption properties of dextren based polelectrolyte displacers in ion-exchange systems. J. Chromat. 630, 37-52.
13. Gear, C. W., 1971, Simultaneous numerical solution of differential/algebraic equations. IEEE Trans. Circut Theory 18, 89-95.
14. Gerstner, J. A. and Cramer, S. M., 1992, Cation exchange displacement chromatography of proteins with protamine displacers: effect of induced salt gradients. Biotechnol. Prog. 8, 540-545.
15. Glükauf, E., 1946, Contributions to the theory of chromatography. Proc. R. Soc. London Ser. A 186, 35-57.
16. Gu, T., Tsai, G. and Ladisch, M. R., 1990, Displacement effect in multicomponent chromatography, A.I.Ch.E. J. 36, 1156-1162.
17. Helfferich, F. and Klein, G., 1970, Multicomponent Chromatography: Theory of Interference, Marcel Dekker, New York.
18. Horváth, Cs., 1985, Displacement chromatography: yesterday, today and tomorrow, In The Science of Chromatography (Journal of Chromatography Library, 32) (Edited by Bruner, F.). Elsevier, Amsterdam.
19. Jayaraman, G., Gadam, S. D. and Cramer, S. M., 1993, Ion-exchange displacement chromatography of proteins: dextran based polyelectrolytes as high affinity displacers. J. Chromatogr. 630, 53-68.
20. Petzold, L. A., 1983, A description of DASSL: a differential/algebraic system solver. Scient. Comput. 1, 65.
21. Phillips, M. W., Subramanian, G. and Cramer, S. M., 1988, Theoretical optimization of operating parameters in non-ideal displacement chromatography. J. Chromatogr. 454, 1-21.
22. Regnier, F. E., 1983, High performance liquid chromatography of biopolymers. Science 222, 245-252.
23. Rhee, H.-K. and Amundson, N. R., 1982, Analysis of multicomponent separation by displacement development. A.I.Ch.E. J. 28, 423-433.
24. Tisehus, A., 1943a, Studies über adsorptionsanalyse, I. Kolloid Z. 105, 101.
25. Tiselius, A., 1943b, Displacement development in adsorption analysis. Arkiv Kemi. Mineral. Geol. 16A, 1.
26. Velayudhan, A., 1990, Studies in nonlinear chromatography, dissertation, Yale University.
27. Velayudhan, A. and . Horváth, Cs., 1988, Preparative chromatography of proteins analysis of the multivalent ion-exchange formalism. J. Chromatogr. 443, 13-29.
28. Vigh, G., Quintero, G. and Farkas, G., 1990, Displacement chromatography on cyclodextrin-silicas. J. Chromatogr. 506, 481-493.
29. Wankat, P. C., 1990, Rate Controlled Separations. Elsevier Science, New York.
30. Yu, Q. and Do, D. D., 1991, Computer simulations of displacement chromatography of systems with species-dependent saturation capacities. J. Chromatogr. 538, 285-292.
31. Yu, Q. and Wang, N.-H., 1989, Computer simulations of the dynamics of multicomponent ion exchange and adsorption in fixed beds - gradient-directed moving finite element method. Comput. Chem. Engng 13, 915-926.