Increased basal REM sleep but no difference in dark induction or light suppression of REM sleep in FLinders rats with cholinergic supersensitivity

Neuropsychopharmacology

Volumn 15, Issue 1, 1996, Pages 45-51

  Benca, Ruth M ^a,d   Overstreet, David E ^b   Gilliland, Marcia A ^c   Russell, Dawn ^c   Bergmann, Bernard M ^c   Obermeyer, William H ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d University of Wisconsin Health   (United States)

Author keywords

Acetylcholine; Depression; Hypercholinergic rats; Light; REM sleep

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DEPRESSION; HYPERSENSITIVITY; LIGHT; NONHUMAN; PRIORITY JOURNAL; RAT; REM SLEEP;

EID: 0030200801     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0893-133X(95)00154-6     Document Type: Article

References (24)

1. Benca RM, Bergmann BM, Leung C, Nummy D, Rechtschaffen A (1991): Rat strain differences in response to dark pulse triggering of paradoxical sleep. Physiol Behav 49:83-87
2. Benca RM, Obermeyer WH, Thisted RA, Gillin JC (1992): Sleep and psychiatric disorders: A meta-analysis. Arch Gen Psychiatr 29:651-668
3. Bergmann BM, Winter JB, Rosenberg RS, Rechtschaffen A (1987): NREM sleep with low-voltage EEG in the rat. Sleep 10:1-11
4. Bergmann BM, Kushida CA, Everson CA, Gilliland MA, Obermeyer WH, Rechtschaffen A (1989): Sleep deprivation in the rat: II. Methodology. Sleep 12:5-12
5. Borbély AA (1987): The S-deficiency hypothesis of depression and the two-process model of sleep regulation. Pharmacopsychiatry 20:23-29
6. Coble PA, Kupfer DJ, Spiker DG, Neil JF, McPartland RJ (1979): EEG sleep in primary depression: A longitudinal placebo study. J Affective Disorders 1:131-138
7. Domino EF, Yamamoto K, Dren AT (1968): Role of cholinergic mechanisms in states of wakefulness and sleep. Prog Brain Res 28:113-133
8. Fishman R, Roffwarg HP (1972): REM sleep inhibition by light in the albino rat. Exp Neurol 36:166-178
9. Hauri PJ, Chernik D, Hawkins DR, Mendels J (1974): Sleep of depressed patients in remission. Arch Gen Psychiatr 31:386-391
10. Hernández-Peón R, Chavez-Ibarra G, Morgane PJ, Timolaria C (1963): Limbic cholinergic pathways involved in sleep and emotional behavior. Exp Neurology 8:93-111
11. Kupfer DJ, Gillin JC, Coble PA, Spiker DG, Shaw DH, Holzer B (1981): REM sleep, naps, and depression. Psychiatr Res 5:195-203
12. Leung C, Bergmann BM, Rechtschaffen A, Benca RM (1992): Heritability of dark pulse triggering in paradoxical sleep in rats. Physiol Behav 52:127-131
13. Lisk RD, Sawyer CH (1966): Induction of paradoxical sleep by lights-off stimulation. Proc Soc Exp Biol Med 123: 664-667
14. Mistlberger RE, Bergmann BM, Rechtschaffen A (1987a): Relationships among wake episode lengths, contiguous sleep episode lengths, and electroencephalographic delta waves in rats with suprachiasmatic nuclei lesions. Sleep 10:12-24
15. Mistelberger R, Bergmann B, Rechtschaffen A (1987b): Period-amplitude analysis of rat electroencephalogram: Effects of sleep deprivation and exercise. Sleep 10:508-522
16. Overstreet DH (1986): Selective breeding for increased cholinergic function: Development of a new animal model of depression. Biol Psychiatr 21:49-58
17. Overstreet DH (1993): The Flinders Sensitive Line rat: A genetic model of depression. Neurosci Biobehav Rev 17:51-68
18. Overstreet DH, Janowsky DS (1991): A cholinergic supersensitive model of depression. In Boulton A, Baker G, Martin Iverson M (eds), Neuromethods, vol 19: Animal Models in Psychiatry II. Clifton NJ, Human Press, 81-114
19. Overstreet DH, Russell RW, Helps SC, Messenger M (1979): Selective breeding for differences in sensitivity to the anticholinesterase, DFP. Psychopharmacology 65:15-20
20. Overstreet DH, Rezvani AH, Janowsky DS (1992): Genetic animal models of depression and ethanol preference provide support for cholinergic and serotonergic involvement in depression and alcoholism. Biol Psychiatr 31: 919-936
21. Rechtschaffen A, Dates R, Tobias M, Whitehead WE (1969): The effect of lights-off stimulation on the distribution of paradoxical sleep in the rat. Comm Behav Biol 3:93-99
22. Rush AJ, Erman MK, Giles DE, Schlesser MA, Carpenter G, Vasavada N, Roffwarg HP (1986): Polysomnographic findings in recently drug-free and clinically remitted depressed patients. Arch Gen Psychiatr 43:878-884
23. Shiromani PJ, Overstreet DH, Levy D, Goodrich CA, Campbell SS, Gillin JC (1988): Increased REM sleep in rats selectively bred for cholinergic hyperactivity. Neuropsychopharmacology 1(2): 127-133
24. Steriade M, Curro Dossi RC, Nunez A (1991): Network modulation of a slow intrinsic oscillation of cat thalamocortical neurons implicated in sleep delta waves: Cortically induced synchronization and brainstem cholinergic suppression. J Neurosci 11:3200-3217