Toxicity of sea nettle (Chrysaora quinquecirrha) fishing tentacle nematocyst venom in cultured rat hepatocytes

Toxicon

Volumn 34, Issue 7, 1996, Pages 771-778

  Houck, Heather E ^a   Lipsky, Michael M ^a   Marzella, Louis ^a   Burnett, Joseph V ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; LACTATE DEHYDROGENASE; SEA NETTLE TOXIN; UNCLASSIFIED DRUG; VENOM;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; LIVER CELL CULTURE; MALE; MODEL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALIA; CHRYSAORA QUINQUECIRRHA; URTICA;

EID: 0030200421     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/0041-0101(96)00004-9     Document Type: Article

References (14)

1. Alam S., Jamal Q., Iqbal N. and Alam J. M. (1992) Effects of marine toxins on albino rats. J. College Phys. and Surgeons 2, 73-76.
2. Burnett J. W. (1992) Human injuries following jellyfish stings. MMJ 41, 509-513.
3. Burnett J. W., Long K. O. and Rubinstein H. M. (1992) Beachside preparation of jellyfish nematocyst tentacles. Toxicon 30, 794-796.
4. Calton G. J., Burnett J. W., Garbus J. and Max S. R. (1973) The effects of Chrysaora and Physalia venoms on mitochondrial structure and function. Proc. Soc. exp. Biol. Med. 43, 971-977.
5. Cobbs C. S., Drzymala R. E., Shamoo A. E., Carlton F. J. and Burnett J. W. (1983) Sea nettle (Chrysaora quinquecirrha) lethal factor: effect on black lipid membranes. Toxicon 21, 558-561.
6. DeBernardi M. A., Seki T. and Brooker G. (1991) Inhibition of cAMP accumulation by intracellular calcium mobilization in C6-2B cells stably transfected with substance K receptor cDNA. Proc. natn. Acad. Sci. U.S.A. 88, 9257-9261.
7. Dubois J. M., Tanguy J. and Burnett J. W. (1983) Ionic channels induced by sea nettle toxin in the nodal membrane. Biophys. Soc. 42, 199-202.
8. Garcia P. J., Schein R. M. H. and Burnett J. W. (1994) Fulminant hepatic failure from a sea anemone sting. Ann. Int. Med. 120, 665-666.
9. Klaunig J. E., Goldblatt F. J., Hinton D. E., Lipsky M. M., Chacko J. and Trump B. F. (1981) Mouse liver cell culture. In Vitro 10, 913-915.
10. Koski C. L., Ramm L. E., Hammer C. H., Mayer M. M. and Shin M. L. (1983) Cytolysis of nucleated cells by complement: cell death displays multi-hit characteristics. Proc. natn. Acad. Sci. U.S.A. 80, 3816-3820.
11. Long-Rowe K. O. and Burnett J. W. (1994) Characteristics of hyaluronidase and hemolytic activity in fishing tentacle nematocyst venom of Chrysaora quinquecirrha. Toxicon 32, 165-174.
12. Muhvich K. H., Sengottuvelu S., Manson P. N., Myers R. A. M., Burnett J. W. and Marzella L. (1991) Pathophysiology of sea nettle (Chrysaora quinquecirrha) envenomation in a rat model and the effects of hyperbaric oxygen and verapamil treatment. Toxicon 7, 857-866.
13. Trump B., Berezesky I. K., Smith M. W. and Phelps P. (1992) The role of ionized cytosolic calcium in injury and recovery from anoxia and ischemia. MMJ 41, 505-508.
14. van de Water B., Zoeteweif J. P., de Bont H. J. G. M., Mulder G. J. and Nagelkerke J. F. (1994) Role of mitochondrial calcium in the oxidative stress-induced dissipation of the mitochondrial membrane potential. Am. Soc. Biochem. molec. Biol. 269(20), 14546-14552.