Recombinant superoxide dismutase (SOD) administered by aerosol inhibits respiratory syncytial virus infection in cotton rats

Antiviral Research

Volumn 31, Issue 3, 1996, Pages 173-184

  Wyde, Philip R ^a   Moore, Donna K ^a   Miles Pimentel, D ^a   Gilbert, Brian E ^a   Nimrod, Rami ^b   Panet, Amos ^b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Kiryat Weizmann   (Israel)

Author keywords

Antiviral; Cotton rats; CuZnSOD; MnSOD; Respiratory syncytial virus; Respiratory syncytial virus, RSV; SOD

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MANGANESE; RECOMBINANT SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

AEROSOL; ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; FEMALE; INHALATIONAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VIRUS INFECTION; VIRUS INHIBITION;

ANIMALIA; GOSSYPIUM HIRSUTUM; RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS; SIGMODON; SYNCYTIAL VIRUS;

EID: 0030200337     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-3542(95)06967-4     Document Type: Article

References (32)

1. 2 generation by xanthine oxidase of pathogenesis of influenza virus infection in mice. J. Clin. Invest. 85, 739-745.
2. Andersen, A.A. (1958) New sampler for the collection, sizing, and enumeration of viable airborne particles. J. Bacteriol. 76, 471-484.
3. Beck, Y., Bartfeld, D., Yavin, Z., Levanon, A., Gorecki, M. and Hartman, J.R. (1988) Efficient production of active human manganese Superoxide dismutase in Escherichia coli. Biotechnology 6, 930-935.
4. Blake, D.R. (1983) Effect of a specific iron chelating agent on animal models of inflammation. Ann. Rheum. Dis. 42, 89-93.
5. Buffinton, G.D., Christen, S., Peterhans, E. and Stocker, R. (1992) Oxidative stress in lungs of mice infected with influenza A virus. Free Rad. Res. Commun. 16, 99-110.
6. Fox, R.B., Hoidal, J.R., Brown, D.M. and Repine, J.E. (1981) Pulmonary inflammation due to oxygen toxicity: involvement of chemotactic factor and polymorphonuclear leukocytes. Am. Rev. Respir. Dis. 123, 521-523.
7. Freeman, B.A. and Crapo, J.D. (1981) Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria. J. Biol. Chem. 256, 10986-10992.
8. Fridovich, I. (1976) Oxygen radicals, hydrogen peroxide and oxygen toxicity. In: W.A. Pryor (Ed). Free Radicals in Biology, pp. 239-277. Academic Press, New York.
9. Gilbert. B.E. and Wyde, P.R. (1988) Pharmacokinetics of ribavirin aerosol in mice. Antimicrob. Agents Chemother. 32. 117-121.
10. Gilbert. B.E., Wyde, P.R., Wilson. S.Z. and Meyerson. L.R. (1993) SP-303 small-particle aerosol treatment of influenza A virus infection in mice and respiratory syncytial virus infection in cotton rats. Antiviral Res. 21. 37-45.
11. Glezen, W.P.. Loda, F.A. and Denny. F.W. (1982) The parainfluenza viruses. In: A.S. Evans (Ed), Viral Infections of Humans: Epidemiology and Control. pp. 337-349. Plenum Press, New York.
12. Hartman, J.R., Geller, T., Yavin, Z.. Bartfeld, D.. Kanner, D., Aviv, H. and Gorecki, M. (1986) High-level expression of enzymatically active human Cu Zn superoxide dismutase in Escherichia coli. Proc. Natl. Acad. Sci. USA 83. 7142-7146.
13. Hatch. T.F. and Gross, P. (1964) Experimental studies on deposition of inhaled aerosols. In: T.F. Hatch and P. Gross (Eds), Pulmonary Deposition and Retention of Inhaled Aerosols. pp. 45-65. Academic Press, New York.
14. Keller, G.A., Warner, T.G., Steimer, K.S. and Hallewell. R.A. (1991) CuZn superoxide dismutase is a peroxisomal enzyme in human flbroblasts and hepatoma cells. Proc. Natl. Acad. Sci. USA 88, 7381-7385.
15. Knight, V. and Gilbert, B. (1988) Antiviral therapy with small particle aerosols. Eur. J. Clin. Microbiol. Infect. Dis. 71, 721-731.
16. Loosli, C.G. (1949) The pathogencsis and pathology of experimental air-borne influenza virus A infections in mice. J. Infect. Dis. 84, 153-168.
17. Loosli, C.G., Buckley. R.D., Hardy. J.D., Hertweck, M.S., Kow, S.H.. Serebrin, R.. Ryan. D.P. and Stinson, S.F. (1971) The pathogenesis of postinfluenzal collapse of the lungs of mice. Trans. Assoc. Am. Physicians 84, 182-189.
18. Marklund, S.L. (1984) Extracellular superoxide dismutase and other superoxide dismutase isozymes in tissues from nine mammalian species. Biochem. J. 222, 649-655.
19. Maeda, H. and Akaike. T. (1991) Oxygen free radicals as pathogenic molecules in viral diseases. Proc. Soc. Exp. Biol. Med. 198, 721-726.
20. May. K.R. (1973) The collision nebulizer: description, performance and application. Aerosol Sci. 4, 235-243.
21. Oda. T., Akaike. T., Hamamoto. T., Suzuki, F., Hirano, T. and Maeda, H. (1989) Oxygen radicals in influenza-induced pathogenesis and treatment with pyran polymer-conjugated SOD. Science 244, 974-976.
22. Parrot, R.H., Kim, H.W., Arrobio, J.O.. Nodes, D.S., Murphy, B.R., Brandt, CD.. Camargo. E., and Chanock, R.M. (1973) Epidemiology of respiratory syncytial virus infection in Washington, D.C. Am. J. Epidemiol. 98: 289-300.
23. Phalen. R.F. (1984) Inhalation Studies: Foundations and Techniques, p. 222. CRC Press, Boca Raton, FL.
24. Raineri, I., Huang, T.T., Epstein, C.J. and Epstein, L.B. (1996) Antisense manganese superoxide dimutase mRNA inhibits the antiviral action of interferon-gamma and interferon-alpha. J. Interferon and Cytokine Res. 16, 61-68.
25. Rhodes, A.J. and Van Rooyen. C.E. (1953) Textbook of Virology (2nd edition), pp. 66-69. Williams and Wilkins Co., Baltimore. MD.
26. Shasby. D.M., Fox, R.B.. Harada, R.N. and Repine, J.E. (1982) Reduction of the edema of acute hyperoxic injury by granulocyte depletion. J. Appl. Physiol. 52, 1237-1244.
27. Tate. R.M. and Repine. J.E. (1983) Neutrophils and the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 128, 552-559.
28. Tsan, M.-F. (1993) Superoxide dismutase and pulmonary oxygen toxicity. Proc. Soc. Exp. Biol. Med. 203, 286-290.
29. Wilson. S.Z.. Knight, V., Wyde, P.R., Drake, S. and Couch, R.B. (1980) Amantadine and ribavirin aerosol treatment of influenza A and B infection in mice. Antimicrob. Agents and Chemother. 17, 642-648.
30. Wyde, P.R., Couch, R.B., Mackler, B.R., Cate, T.R. and Levy, B. (1977) Effects of low and high passage influenza virus infection in normal and nude mice. Infect. Immun. 15, 221-229.
31. Wyde. P.R., Sun, C.-S., Wilson. S.Z. and Knight, V. (1985) Duration of effect of interferon aerosol prophylaxis of vesicular stomatitis virus infection in mice. Antimicrob. Agents Chemother. 27, 60-64.
32. Wyde, P.R.. Meyerson, L.R. and Gilbert, B.E. (1993) An in vitro evaluation of the antiviral activity of SP-303, an Euphorbiaceae shrub extract. against a panel of respiratory viruses. Drug Dev. Res. 28, 467-472.