Comparative activity of twelve beta-lactam drugs tested against penicillin-resistant Streptococcus pneumoniae from five medical centers: Effects of serum protein and capsular material on potency and spectrum as measured by reference tests

Diagnostic Microbiology and Infectious Disease

Volumn 25, Issue 3, 1996, Pages 137-141

  Johnson, David M ^a   Doern, Gary V ^b   Haugen, Thomas A ^c   Hindler, Janet ^d   Washington, John A ^e   Jones, Ronald N ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UCLA MEDICAL CENTER   (United States)

^e LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; BETA LACTAM ANTIBIOTIC; CEFOTAXIME; CEFTAZIDIME; CEFTIZOXIME; CEFTRIAXONE; CEFUROXIME; CLAVULANIC ACID; PENICILLIN G; PIPERACILLIN; SULBACTAM; TAZOBACTAM; TICARCILLIN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE;

EID: 0030200303     PISSN: 07328893     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0732-8893(96)00126-5     Document Type: Article

References (18)

1. Appelbaum PC (1994) Antibiotic-resistant pneumococci: Facts and fiction. J Chemother 6(Suppl 4):7-16.
2. Barry AL, Brown SD, Fuchs PC (1996) In vitro activity of ceftizoxime, ceftazidime, cefuroxime, ceftriaxone, cefotaxime, and penicillin against Streptococcus pneumoniae as determined by three quantitative methods. Eur J Clin Microbial Infect Dis 15:344-346.
3. Bradley JS, Connor JD (1991) Ceftriaxone failure in meningitis caused by Streptococcus pneumoniae with reduced susceptibility to beta-lactam antibiotics. Pediatr Infect Dis J 10:871-873.
4. Breiman RF, Butler JC, Tenover FC, Elliott JA, Facklam RR (1994) Emergence of drug-resistant pneumococcal infections in the United States. J Am Med Assoc 271:1831-1835.
5. Cormican MG, Erwin ME, Jones RN (1995) Bactericidal activity of cefotaxime, desacetylcefotaxime, rifampin, and various combinations tested at cerebrospinal fluid levels against penicillin-resistant Streptococcus pneumoniae. Diagn Microbiol Infect Dis 22:119-123.
6. Doern GV, Brueggemann A, Holley Jr HP, Rauch AM (1996) Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: Results of a 30-center national surveillance study. Antimicrob Agents Chemother 40:1208-1213.
7. Figueiredo AM, Connor JD, Severin A, Vaz Pas MV, Tomas A (1992) A pneumococcal clinical isolate with high level resistance to cefotaxime and ceftriaxone. Antimicrob Agents Chemother 36:886-889.
8. Friedland JR, McCracken Jr GH (1994) Management of infections caused by antibiotic-resistant Streptococcus pneumoniae. N Engl J Med 331:377-382.
9. Gomez J, Banos V, Gomez JR, Herraro F, Nunez ML, Canteras M, Valdes M (1995) Clinical significance of pneumococcal bacteremias in a general hospital: A prospective study 1989-1993. J Antimicrob Chemother 36: 1021-1030.
10. Jones RN (1995) Cefotaxime and desacetylcefotaxime antimicrobial interactions. The clinical relevance of enhanced activity: A review. Diagn Microbiol Infect Dis 22: 19-33.
11. Jones RN, Kehrberg EN, Erwin ME, Anderson SC (1994) Prevalence of important pathogens and antimicrobial activity of parenteral drugs at numerous centers in the United States. I. Study on the threat of emerging resistances: Real or perceived. Diagn Microbiol Infect Dis 19: 203-215.
12. National Committee for Clinical Laboratory Standards (1993a) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. Approved standard M7-A3. National Committee for Clinical Laboratory Standards, Villanova, PA.
13. National Committee for Clinical Laboratory Standards (1995) Performance standards for antimicrobial susceptibility testing. 6th International Supplement, M100-S6. National Committee for Clinical Laboratory Standards, Villanova, PA.
14. Raymond J, Bingen E, Doit C, Brahimi N, Bergeret M, Badoual J, Gendrel D (1995) Failure of cefotaxime treatment in a patient with penicillin-resistant pneumococcal meningitis and confirmation of nosocomial spread by random amplified polymorphic DNA analysis. Clin Infect Dis 21:234-235.
15. Sloas MM, Barrett FF, Chesney J, English K, Hill BC, Tenover FK, Leggiardro RJ (1992) Cephalosporin treatment failure in penicillin and cephalosporin-resistant Streptococcus pneumoniae meningitis. Pediatr Infect Dis J 11:662-666.
16. Stratton CW, Aldridge KE, Gelfand MS (1995) In vitro killing of penicillin-susceptible, -intermediate, and -resistant strains of Streptococcus pneumoniae by cefotaxime, ceftriaxone, and ceftizoxime: A comparison of bactericidal and inhibitory activity with achievable CSF levels. Diagn Microbiol Infect Dis 22:35-42.
17. Trang JM, Jacobs RF, Kerns GL, Brown AL, Wells TG, Underwood FL, Kluza RB (1985) Cefotaxime and desacetylcefotaxime pharmacokinetics in infants and children with meningitis. Antimicrob Agents Chemother 28:791-795.
18. Viladrich PF, Cabellos C, Pallares R, Tubau F, Martinez-Lacasa J, Linares J, Gudiol F (1996) High doses of cefotaxime in treatment of adult meningitis due to Streptococcus pneumoniae with decreased susceptibilities to broad-spectrum cephalosporins. Antimicrob Agents Chemother 40:218-220.