Expression of Dictyostelium early gene, dutA, is indepentdent of cAMP pulses but dependent on protein kinase A

FEMS Microbiology Letters

Volumn 140, Issue 2-3, 1996, Pages 121-124

  Kumimoto, Hiroshi ^a,c   Yoshida, Hiderou ^b,c   Okamoto, Koji ^c  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b Kyoto Research Park   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

cAMP; Dictyostelium discoideum; Gene expression; Protein kinase A

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE;

ARTICLE; CONTROLLED STUDY; DICTYOSTELIUM DISCOIDEUM; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0030199885     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1097(96)00158-9     Document Type: Article

References (20)

1. [1] Firtel, R.A. (1995) Integration of signaling information in controlling cell-fate decisions in Dictyostelium. Genes Dev. 9, 1427-1444.
2. [2] Devreotes, P.N. (1982) Chemotaxis. In: Development of Dictyostelium discoideum (W.F. Loomis, Ed.), pp. 117-168, Academic Press, New York.
3. [3] Gomer, R.H., Armstrong, D., Leichtling, B.H. and Firtel, R. A. (1986) cAMP induction of prespore and prestalk gene expression in Dictyostelium is mediated by cell-surface cAMP receptor. Proc. Natl. Acad. Sci. USA 83, 8624-8628.
4. [4] Haribabu, B. and Dottin, R.P. (1986) Pharmacological characterization of cyclic AMP receptors mediating gene regulation in Dictyostelium discoideum. Mol. Cell. Biol. 6, 2402-2408.
5. [5] Oyama, M. and Blumberg, D.D. (1986) Interaction of cAMP with the cell-surface receptor induces cell-type-specific mRNA accumulation in Dictyostelium discoideum. Proc. Natl. Acad. Sci. USA 83, 4819-4823.
6. [6] Saxe III, C.L., Johnson, R.L., Devreotes, P.N. and Kimmel, A.R. (1991) Expression of a cAMP receptor gene of Dictyostelium and evidence for a multigene family. Genes Dev. 5, 1-8.
7. [7] Mann, S.K.O., Pinko, C. and Firtel, R.A. (1988) cAMP regulation of early gene expression in signal transduction mutants of Dictyostelium. Dev. Biol. 130, 294-303.
8. [8] Soede, R.D.M., Insall. R.H., Devreotes, P.N. and Schaap, P.R. (1994) Extracellular cAMP can restore development in Dictyostelium cells lacking one, but not two subtypes of early cAMP receptors (cars). Evidence for involvement of carl in aggregative gene expression. Development 120, 1997-2002.
9. [9] Yoshida, H., Yamada, Y. and Okamoto, K. (1991) DC6, a novel type of Dictyostelium discoideum gene regulated by secreted factors but not by cAMP. Differentiation 46, 161-166.
10. [10] Yoshida, H., Kumimoto, H. and Okamoto, K. (1994) dutA RNA functions as an untranslatable RNA in the development of Dictyostelium discoideum. Nucleic Acids Res. 22, 41-46.
11. [11] Kumimoto, H., Yoshida, H. and Okamoto, K. (1995) RNA polymerase II transcribes Dictyostelium untranslatable gene, dutA, specifically in the developmental phase. Biochem. Biophys. Res. Commun. 216, 273-278.
12. [12] Pitt, G.S., Milona, N., Borleis, J., Lin, K.C., Reed, R.R. and Devreotes, P.N. (1992) Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium. Cell 69, 305-315.
13. [13] Segall, J.E., Kuspa, A., Shaulsky, G., Ecke, M., Maeda, M., Gaskins, C., Firtel, R.A. and Loomis, W.F. (1995) A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium. J. Cell Biol. 128, 405-413.
14. [14] Vauti, F., Morandini, P., Blusch, J., Sachse, A. and Nellen W. (1990) Regulation of the discoidin-1 gamma-gene in Dictyostelium discoideum: identification of individual promoter elements mediating induction of transcription and repression by cyclic AMP. Mol. Cell Biol. 10, 4080-4088.
15. [15] Mann, S.K.O. and Firtel, R.A. (1991) A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium. Mech. Dev. 35, 89-101.
16. 2+ levels. Dev. Biol. 168, 179-188.
17. [17] Schulkes, C. and Schaap, P. (1995) cAMP-dependent protein kinase activity is essential for preaggregative gene expression in Dictyostelium. FEBS Lett. 368, 381-384.
18. [18] Wu, L., Hansen, D., Franke, J., Kessin, R.H. and Podgorski, G.J. (1995) Regulation of Dictyostelium early development genes in signal transduction mutants. Dev. Biol. 171, 149-158.
19. [19] Rathi, A., Kayman, S.C. and Clarke, M. (1991) Induction of gene expression in Dictyostelium by prestarvation factor, a factor secreted by growing cells. Dev. Genet. 12, 82-87.
20. [20] Gomer, R.H., Yuen, I.S. and Firtel, R.A. (1991) A secreted 80 × 10(3)Mr protein mediates sensing of cell density and the onset of development in Dictyostelium. Development 112, 269-278.