The traA gene of the Enterococcus faecalis conjugative plasmid pPD1 encodes a negative regulator for the pheromone response

Plasmid

Volumn 36, Issue 1, 1996, Pages 55-61

  Tanimoto, Koichi ^a   Tomita, Haruyoshi ^a   Ike, Yasuyoshi ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PHEROMONE; TRAA PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ENTEROCOCCUS FAECALIS; GENE CLUSTER; GENE TRANSFER; GENETIC RECOMBINATION; NONHUMAN; PLASMID; REGULATOR GENE;

ENTEROCOCCUS FAECALIS; STREPTOCOCCUS;

EID: 0030199832     PISSN: 0147619X     EISSN: None     Source Type: Journal    
DOI: 10.1006/plas.1996.0032     Document Type: Article

References (21)

1. CHUNG, J. W., BENSING, B. A., AND DUNNY, G. M. (1995). Genetic analysis of a region of the Enterococcus faecalis plasmid pCF10 involved in positive regulation of conjugative transfer functions. J. Bacteriol. 177, 2107-2117.
2. CLEWELL, D. B. (1981). Plasmids, drug resistance, and gene transfer in the genus Streptococcus. Microbiol. Rev. 45, 409-436.
3. CLEWELL, D. B., TOMICH, P. K., GAWRON-BURKE, M. C., FRANKE, A. E., YAGI, Y., AND AN, F. Y. (1982). Mapping of Streptococcus faecalis plasmids pAD1 and pAD2 and studies relating to transposition of Tn917. J. Bacteriol. 152, 1220-1230.
4. CLEWELL, D. B. (1993a). Bacterial sex pheromone-induced plasmid transfer. Cell 73, 9-12.
5. CLEWELL, D. B. (1993b). Sex pheromones and the plasmid-encoded mating response in Enterococcus faecalis, pp. 349-367. In "Bacterial Conjugation" (D. B. Clewell, Ed.). Plenum, New York.
6. DUNNY, G. M., BROWN, B. L., AND CLEWELL, D. B. (1978). Induced cell aggregation and mating in Streptococcus faecalis: Evidence for a bacterial sex pheromone. Proc. Natl. Acad. Sci. USA 75, 3479-3483.
7. DUNNY, G. M., CRAIG, R. A., CARRON, R. L., AND CLEWELL, D. B. (1979). Plasmid transfer in Streptococcus faecalis: Production of multiple sex pheromones by recipients. Plasmid 2, 454-465.
8. DUNNY, G. M., LEONARD, B. A. B., AND HEDBERG, P. J. (1995). Pheromone-inducible conjugation in Enterococcus faecalis: Interbacterial and host-parasite chemical communication. J. Bacteriol. 177, 871-876.
9. FUJIMOTO, S., HASHIMOTO, H., AND IKE, Y. (1991). Low cost device for electrotransformation and its application to the highly efficient transformation of Escherichia coli and Enterococcus faecalis. Plasmid 26, 131-135.
10. FUJIMOTO, S., TOMITA, H., WAKAMATSU, E., TANIMOTO, K., AND IKE, Y. (1995). Physical mapping of the conjugative bacteriocin plasmid pPD1 of Enterococcus faecalis and identification of the determinant related to the pheromone response. J. Bacteriol. 177, 5574-5581.
11. IKE, Y., CRAIG, R. A., WHITE, B. A., YAGI, Y., AND CLEWELL, D. B. (1983). Modification of Streptococcus faecalis sex pheromones after acquisition of plasmid DNA. Proc. Natl. Acad. Sci. USA 80, 5369-5373.
12. IKE, Y., AND CLEWELL, D. B. (1984). Genetic analysis of the pAD1 pheromone response in Streptococcus faecalis, using transposon Tn917 as an insertional mutagen. J. Bacteriol. 158, 777-783.
13. KAO, S., OLMSTED, S. B., VIKISNINS, A. S., GALLO, J. C., AND DUNNY, G. M. (1991). Molecular and genetic analysis of a region of plasmid pCF10 containing positive control genes and structural genes encoding surface proteins involved in pheromone-inducible conjugation in Enterococcus faecalis. J. Bacteriol. 173, 7650-7664.
14. PONTIUS, L. T., AND CLEWELL, D. B. (1992). Regulation of the pAD1-encoded sex pheromone response in Enterococcus faecalis: nucleotide sequence analysis of traA. J. Bacteriol. 174, 1821-1827.
15. RUHFEL, R. E., MANIAS, D. A., AND DUNNY, G. M. (1993). Cloning and characterization of a region of the Enterococcus faecalis conjugative plasmid pCF10, encoding a sex pheromone-binding function. J. Bacteriol. 175, 5253-5259.
16. SAMBROOK, J., FRITSCH, E. F., AND MANIATIS, T. (1989). "Molecular Cloning: A Laboratory Manual," 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
17. TANIMOTO, K., AND CLEWELL, D. B. (1993). Regulation of the pAD1-encoded sex pheromone response in Enterococcus faecalis: Expression of the positive regulator TraE1. J. Bacteriol. 175, 1008-1018.
18. TAO, L., AND FERRETTI, J. J. (1991). Cloning vectors with streptococcal resistance genes and an Escherichia coli origin of replication which can be used for cloning of streptococcal origins of replication or for gene inactivation in streptococci, p. 305. In "Genetics and Molecular Biology of Streptococci, Lactococci, and Enterococci" (G. M. Dunny, P. P. Cleary, and L. L. McKay, Eds.). Am. Soc. Microbiol., Washington, DC.
19. TOMICH, P. K., AN, F. Y., AND CLEWELL, D. B. (1980). Properties of erythromycin-inducible transposon Tn917 in Streptococcus faecalis. J. Bacteriol. 141, 1366-1374.
20. WEAVER, K. E., AND CLEWELL, D. B. (1990). Regulation of the pAD1 sex pheromone response in Enterococcus faecalis: Effects of host strain and traA, traB, and C region mutants on expression of an E region pheromone-inducible lacZ fusion. J. Bacteriol. 172, 2633-2641.
21. YAGI, Y., KESSLER, R. E., SHOW, J. H., LOPATIN, D. E., AN, F. Y., AND CLEWELL, D. B. (1983). Plasmid content of Streptococcus faecalis strain 39-5 and identification of a pheromone (cPD1)-induced surface antigen. J. Gen. Microbiol. 129, 1207-1215.