In vivo absorption spectrum of disulphonated aluminium phthalocyanine in a murine tumour model

Journal of Photochemistry and Photobiology B: Biology

Volumn 34, Issue 2-3, 1996, Pages 229-235

  Cubeddu, Rinaldo ^a   Canti, Gianfranco ^b   Musolino, Mario ^a   Pifferi, Antonio ^a   Taroni, Paola ^a   Valentini, Gianluca ^a  

^a POLITECNICO DI MILANO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Absorption spectrum; Photodynamic therapy; Photosensitizers; Phthalocyanine; Reflectance; Time resolved reflectance

Indexed keywords

PHOTOSENSITIZING AGENT; PHTHALOCYANINE ALUMINUM;

ABSORPTION SPECTROSCOPY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER MORTALITY; CANCER SURVIVAL; CONTROLLED STUDY; DRUG ABSORPTION; DRUG EFFICACY; FIBROSARCOMA; INTRADERMAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; LEUKEMIA L 1210; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL;

ANIMALIA; MURINAE;

EID: 0030199809     PISSN: 10111344     EISSN: None     Source Type: Journal    
DOI: 10.1016/1011-1344(95)07258-6     Document Type: Article

References (16)

1. [1] See for example: B.C. Wilson and S.L. Jacques, Optical reflectance and transmittance of tissues: principles and applications, IEEE J. Quantum Electron., 26 (1990) 2186-2199.
2. [2] I. Rosenthal, Phthalocyanines as photodynamic sensitizers, Photochem. Photobiol., 53 (1991) 859-870.
3. [3] M. Ambroz, A. Beeby, A.J. MacRobert, M.S.C. Simpson, R.K. Svensen and D. Phillips, Preparative, analytical and fluorescence spectroscopic studies of sulphonated aluminum phthalocyanine photosensitizes, J. Photochem. Photobiol. B: Biol., 9 (1991) 87-95.
4. [4] K. Berg, J.C. Bommer and J. Moan, Evaluation of sulfonated aluminum phthalocyanines for use in photochemotherapy. A study on the relative efficiencies of photoinactivation, Photochem. Photobiol., 49 (1989) 587-594.
5. [5] M. Ambroz, A.J. MacRobert, J. Morgan, G. Rumbles, M.S.C. Foley and D. Phillips, Time-resolved spectroscopy and intracellular imaging of disulphonated aluminium phthalocyanine, J. Photochem. Photobiol. B: Biol., 22 (1993) 105-117.
6. [6] H.L.L.M. van Leengoed, N. van der Veen, A.A.C. Versteeg, R. Ouellet, J.E. van Lier and W.M. Star, In vivo photodynamic effects of phthalocyanines in a skin-folded observation chamber model: role of central metal ion and degree of sulfonation, Photochem. Photobiol., 58 (1993) 575-580.
7. [7] G. Canti, P. Franco, O. Marelli, R. Cubeddu, P. Taroni and R. Ramponi, Comparative study of the therapeutic effect of photoactivated hematoporphyrin derivative and aluminum disulphonated phthalocyanines on tumor bearing mice, Cancer Lett., 53 (1990) 123-127.
8. 2Pc in tumor bearing mice, Anti-Cancer Drugs, 3 (1992) 139-142.
9. [9] R. Cubeddu, M. Musolino, A Pifferi, P. Taroni and G. Valentini, Time-resolved reflectance: a systematic study for the application to the optical characterization of tissues, IEEE J. Quantum Electron., 30 (1994) 2421-2430.
10. [10] M.S. Patterson, B. Chance and B.C. Wilson, Time-resolved reflectance and transmittance for the noninvasive measurement of tissue optical properties, Appl. Opt., 28 (1989) 2331-2336.
11. [11] R.G. Perry, P.D. Smith, S. Evans and H.I. Pass, Intravenous vs intraperitoneal sensitizer: implications for intraperitoneal photodynamic therapy, Photochem. Photobiol., 53 (1991) 335-340.
12. [12] In vivo Cancer Models Developmental Therapeutic Program, Division of Cancer Treatment, National Cancer Institute, NIH Publication N. 842635, February 19884.
13. [13] S. Siegel, Non Parametric Statistics, McGraw-Hill, New York, 1956.
14. [14] J. Moan, K. Berg, J.C. Bommer and A. Western, Action spectra of phthalocyanines with respect to photosensitization of cells, Photochem. Photobiol., 56 (1992) 171-175.
15. [15] T.J. Farrell, M.S. Patterson and B. Wilson, A diffusion theory model of spatially resolved, steady-state diffuse reflectance for the noninvasive determination of tissue optical properties in vivo, Med. Phys., 19 (1992) 879-888.
16. [16] B. Wilson, E.M. Sevick, M.S. Patterson and B, Chance, Time-dependent optical spectroscopy and imaging for biomedical applications, Proc. IEEE, 80 (1992) 918-930.