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Volumn 27, Issue 5, 1996, Pages 795-802

Mechanisms involved in the contractile responses induced by the hydroalcoholic extract of Phyllanthus urinaria on the guinea pig isolated trachea: Evidence for participation of tachykinins and influx of extracellular Ca2+ sensitive to ruthenium red

Author keywords

Calcium; Capsaicin; Capsazepine; Contraction; Extract; Guinea pig trachea; Phyllanthus urinaria; Ruthenium red; Tachykinins; Vanilloid receptor

Indexed keywords

3 [1 (4 CHLOROBENZYL) 5 FLUORO 3 METHYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ALCOHOL; APAFANT; ATROPINE; CALCIUM CHANNEL; CAPSAICIN; CAPSAZEPINE; INDOMETACIN; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MEPYRAMINE; N BENZYL N2 [4 HYDROXY 1 [(1 METHYL 1H INDOL 3 YL)CARBONYL]PROLYL] N METHYL 3 (2 NAPHTHYL)ALANINAMIDE; NICARDIPINE; OMEGA CONOTOXIN; PHYLLANTHUS URINARIA EXTRACT; PLANT EXTRACT; RUTHENIUM RED; SAREDUTANT; STAUROSPORINE; TACHYKININ RECEPTOR; TETRODOTOXIN; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERLUKAST; WATER;

EID: 0030199224     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-3623(95)02106-X     Document Type: Article
Times cited : (15)

References (37)
  • 2
    • 0025778737 scopus 로고
    • Ruthenium red as a capsaicin antagonist
    • Amann R. and Maggi C.A. (1991) Ruthenium red as a capsaicin antagonist. Life Sci. 49, 849-856.
    • (1991) Life Sci. , vol.49 , pp. 849-856
    • Amann, R.1    Maggi, C.A.2
  • 3
    • 0009644628 scopus 로고
    • Some quantitative uses of drug antagonists
    • Arunlakshana O. and Schild H.O. (1959) Some quantitative uses of drug antagonists. Br. J. Pharmac. 14, 48-58.
    • (1959) Br. J. Pharmac. , vol.14 , pp. 48-58
    • Arunlakshana, O.1    Schild, H.O.2
  • 5
    • 0028180334 scopus 로고
    • 2) receptors mediate nonadrenergic noncholinergic contractile responses to electrical stimulation and resiniferatoxin in guinea pig trachea
    • 2) receptors mediate nonadrenergic noncholinergic contractile responses to electrical stimulation and resiniferatoxin in guinea pig trachea. Con. J. Physiol. Pharmac. 72, 182-188.
    • (1993) Con. J. Physiol. Pharmac. , vol.72 , pp. 182-188
    • Charette, L.1    Foulon, D.2    Rodger, I.W.3    Jones, T.R.4
  • 6
    • 0028860917 scopus 로고
    • Analysis of the mechanisms underlying the contractile response induced by the hydroalcoholic extract of Phyllanthus urinaria in the guinea pig urinary bladder in vitro
    • Dias M. A., Campos A. H., Cechinel Filho V., Yunes R. A. and Calixto J. B. (1995) Analysis of the mechanisms underlying the contractile response induced by the hydroalcoholic extract of Phyllanthus urinaria in the guinea pig urinary bladder in vitro. J. Pharm. Pharmac. 471, 846-851.
    • (1995) J. Pharm. Pharmac. , vol.471 , pp. 846-851
    • Dias, M.A.1    Campos, A.H.2    Cechinel Filho, V.3    Yunes, R.A.4    Calixto, J.B.5
  • 7
    • 0025718476 scopus 로고
    • Selective antagonism of capsaicin by capsazepine: Evidence for a spinal receptor site in capsaicin-induced antinociception
    • Dickenson A. H. and Dray A. (1991) Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin-induced antinociception. Br. J. Pharmac. 104, 1045-1049.
    • (1991) Br. J. Pharmac. , vol.104 , pp. 1045-1049
    • Dickenson, A.H.1    Dray, A.2
  • 8
    • 0026702932 scopus 로고
    • Neuropharmacological mechanisms of capsaicin and related substances
    • Dray A. (1992) Neuropharmacological mechanisms of capsaicin and related substances. Biochem. Pharmac. 44, 611-615.
    • (1992) Biochem. Pharmac. , vol.44 , pp. 611-615
    • Dray, A.1
  • 10
    • 0028128078 scopus 로고
    • Inhibition by capsazepine of resiniferatoxin-and capsaicin-induced contractions of guinea pig trachea
    • Ellis J. L. and Undem B. J. (1994) Inhibition by capsazepine of resiniferatoxin-and capsaicin-induced contractions of guinea pig trachea. J. Pharmac. Exp. Ther. 268, 85-89.
    • (1994) J. Pharmac. Exp. Ther. , vol.268 , pp. 85-89
    • Ellis, J.L.1    Undem, B.J.2
  • 11
    • 0028181639 scopus 로고
    • 2 tachykinin receptors in guinea pig and rat bronchopulmonary and vascular systems
    • 2 tachykinin receptors in guinea pig and rat bronchopulmonary and vascular systems. Br. J. Pharmac. 111, 759-768.
    • (1994) Br. J. Pharmac. , vol.111 , pp. 759-768
    • Floch, A.1    Fardin, V.2    Cavero, I.3
  • 13
    • 0027290987 scopus 로고
    • Characterization of tachykinin receptors in ferret trachea by peptide agonists and nonpeptide antagonists
    • Geppetti P., Bertrand C., Bacci E., Huber O. and Nadel J. A. (1993) Characterization of tachykinin receptors in ferret trachea by peptide agonists and nonpeptide antagonists. Am. J. Physiol. 265, L164-169.
    • (1993) Am. J. Physiol. , vol.265
    • Geppetti, P.1    Bertrand, C.2    Bacci, E.3    Huber, O.4    Nadel, J.A.5
  • 15
    • 0027739305 scopus 로고
    • Potent antinociceptive activity of a hydroalcoholic extract of Phyllanthus corcovadensis
    • Gorski F., Corrêa C. R., Filho V. C., Yunes R. A. and Calixto J. B. (1993) Potent antinociceptive activity of a hydroalcoholic extract of Phyllanthus corcovadensis. J. Pharm. Pharmac. 45, 1046-1049.
    • (1993) J. Pharm. Pharmac. , vol.45 , pp. 1046-1049
    • Gorski, F.1    Corrêa, C.R.2    Filho, V.C.3    Yunes, R.A.4    Calixto, J.B.5
  • 16
    • 0023129137 scopus 로고
    • Pharmacology of L-655,240 (3-[1-(4-chlorobenzyl)-5-fluoro-3-methyl-indol-2-yl]2,2-dimethylpropanoil acid); a potent, selective thromboxane/prostaglandin endoperoxide antagonist
    • Hall R. A., Gillard J., Guindon Y., Letts G., Champion E., Ethier D., Evans J. and Yoakin C. (1987) Pharmacology of L-655,240 (3-[1-(4-chlorobenzyl)-5-fluoro-3-methyl-indol-2-yl]2,2-dimethylpropanoil acid); a potent, selective thromboxane/prostaglandin endoperoxide antagonist. Eur. J. Pharmac. 135, 193-201.
    • (1987) Eur. J. Pharmac. , vol.135 , pp. 193-201
    • Hall, R.A.1    Gillard, J.2    Guindon, Y.3    Letts, G.4    Champion, E.5    Ethier, D.6    Evans, J.7    Yoakin, C.8
  • 17
    • 0016345677 scopus 로고
    • Diterpene esters from "Euphorbium" and their irritant and cocarcinogenic activity
    • Hergenhahn H., Kusumoto S. and Hecker E. (1974) Diterpene esters from "Euphorbium" and their irritant and cocarcinogenic activity. Experimentia 30, 1438-1440.
    • (1974) Experimentia , vol.30 , pp. 1438-1440
    • Hergenhahn, H.1    Kusumoto, S.2    Hecker, E.3
  • 20
    • 0027770046 scopus 로고
    • 2-receptor antagonist, selectively inhibits the non-cholinergically mediated neurogenic contraction of guinea pig isolated bronchial muscle
    • 2-receptor antagonist, selectively inhibits the non-cholinergically mediated neurogenic contraction of guinea pig isolated bronchial muscle. J. Pharm. Pharmac. 45, 1037-1041.
    • (1993) J. Pharm. Pharmac. , vol.45 , pp. 1037-1041
    • Kamikawa, Y.1    Shimo, Y.2
  • 21
    • 0025123515 scopus 로고
    • Tachykinin receptors in the airways and lung: What should we block?
    • Maggi C.A. (1990) Tachykinin receptors in the airways and lung: What should we block? Pharmac. Res. 22, 527-540.
    • (1990) Pharmac. Res. , vol.22 , pp. 527-540
    • Maggi, C.A.1
  • 26
    • 0026730445 scopus 로고
    • Capsazepine reversal of the antinociceptive action of capsaicin in vivo
    • Perkins M. N. and Campbell E.A. (1992) Capsazepine reversal of the antinociceptive action of capsaicin in vivo. Br. J. Pharmac. 107, 329-333.
    • (1992) Br. J. Pharmac. , vol.107 , pp. 329-333
    • Perkins, M.N.1    Campbell, E.A.2
  • 27
    • 0028285774 scopus 로고
    • Minireview: Neurokinin receptor subtypes characterized by biological assays
    • Regoti D., Nguyen Q. T. and Jukic D. (1994) Minireview: Neurokinin receptor subtypes characterized by biological assays. Life Sci. 54, 2035-2047.
    • (1994) Life Sci. , vol.54 , pp. 2035-2047
    • Regoti, D.1    Nguyen, Q.T.2    Jukic, D.3
  • 29
    • 0028985507 scopus 로고
    • Further studies on the antinociceptive action of the hydroalcoholic extracts from the plants of the genus Phyllanthus
    • Santos A. R. S., Cechinel Filho V., Yunes R. A. and Calixto J. B. (1995a) Further studies on the antinociceptive action of the hydroalcoholic extracts from the plants of the genus Phyllanthus. J. Pharm. Pharmac. 47, 66-71.
    • (1995) J. Pharm. Pharmac. , vol.47 , pp. 66-71
    • Santos, A.R.S.1    Cechinel Filho, V.2    Yunes, R.A.3    Calixto, J.B.4
  • 31
    • 0029585078 scopus 로고
    • Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus
    • Santos A. R. S., Cechinel Filho V., Yunes R. A. and Calixto J. B. (1995c) Analysis of the mechanisms underlying the antinociceptive effect of the extracts of plants from the genus Phyllanthus. Gen. Pharmacol. 26, 1499-1506.
    • (1995) Gen. Pharmacol. , vol.26 , pp. 1499-1506
    • Santos, A.R.S.1    Cechinel Filho, V.2    Yunes, R.A.3    Calixto, J.B.4
  • 32
    • 0028216061 scopus 로고
    • Nitric oxide pathway-mediated relaxant effect of bradykinin in the guinea pig isolated trachea
    • Schlemper V. and Calixto J. B. (1994) Nitric oxide pathway-mediated relaxant effect of bradykinin in the guinea pig isolated trachea. Br. J. Pharmac. 111, 83-88.
    • (1994) Br. J. Pharmac. , vol.111 , pp. 83-88
    • Schlemper, V.1    Calixto, J.B.2
  • 33
    • 0028175616 scopus 로고
    • The vaniloid (capsaicin) receptor: Receptor type and species differences
    • Szallasi A. (1994) The vaniloid (capsaicin) receptor: receptor type and species differences. Gen. Pharmac. 25, 223-243.
    • (1994) Gen. Pharmac. , vol.25 , pp. 223-243
    • Szallasi, A.1
  • 34
    • 0025110892 scopus 로고
    • Specific binding of resineferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranes
    • Szallasi A. and Blumberg P. M. (1989) Specific binding of resineferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranes. Brain Res. 524, 106-111.
    • (1989) Brain Res. , vol.524 , pp. 106-111
    • Szallasi, A.1    Blumberg, P.M.2
  • 35
    • 0028178250 scopus 로고
    • 3H]resineferatoxin binding of a human vanilloid (capsaicin) receptor in post-mortem spinal cord
    • 3H]resineferatoxin binding of a human vanilloid (capsaicin) receptor in post-mortem spinal cord. Neurosc. Lett. 165, 101-104.
    • (1994) Neurosc. Lett. , vol.165 , pp. 101-104
    • Szallasi, A.1    Goso, C.2
  • 36
    • 0027452376 scopus 로고
    • 3H]resiniferatoxin binding to central (spinal cord and dorsal root ganglia) and peripheral (urinary bladder and airway) vanilloid (capsaicin) receptors in the rat
    • 3H]resiniferatoxin binding to central (spinal cord and dorsal root ganglia) and peripheral (urinary bladder and airway) vanilloid (capsaicin) receptors in the rat. J. Pharmac. Exp. Ther. 267, 728-733.
    • (1993) J. Pharmac. Exp. Ther. , vol.267 , pp. 728-733
    • Szallasi, A.1    Goso, C.2    Blumberg, P.M.3    Manzini, S.4
  • 37
    • 73649209211 scopus 로고
    • Cumulative dose-response curves. II. Technique for making of dose-response curves in isolated organs and the evaluation of drug parameters
    • Van Rossum J. M. (1963) Cumulative dose-response curves. II. Technique for making of dose-response curves in isolated organs and the evaluation of drug parameters. Arch. Int. Pharmocodyn. Ther. 143, 299-330.
    • (1963) Arch. Int. Pharmocodyn. Ther. , vol.143 , pp. 299-330
    • Van Rossum, J.M.1


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