Effects of L-arginine infusion on renal hemodynamics and sodium excretion during hypo-, normo-, and hyperinsulinemia, as studied in dogs

American Journal of Hypertension

Volumn 9, Issue 7, 1996, Pages 681-686

  García Robles, Rafael ^a,b   Villa, Eduardo ^a,b   Serrano, Joaquín ^a,b   Escobar Morreale, Héctor F ^a,b   Piédrola, Gonzalo ^a,b   Ruilope, Luis M ^a,b  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

^b American Society of Hypertension   (United States)

Author keywords

beagle dogs; hyperinsulinemia; L Arginine; renal function; renal vasculature; sodium excretion

Indexed keywords

ARGININE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOG; GLOMERULUS FILTRATION RATE; HYPERINSULINEMIA; INSULIN RELEASE; INSULIN RESISTANCE; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY PLASMA FLOW; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; SODIUM EXCRETION; VASCULARIZATION;

EID: 0030199180     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/0895-7061(96)00033-7     Document Type: Article

References (33)

1. 1. Modan M, Halkin H, Almong S, et al: Hyperinsulinemia: a link between hypertension, obesity and glucose intolerance. J Clin Invest 1985;75:809-817.
2. 2. DeFronzo RA, Cooke CR, Andres R, et al: The effect of insulin on renal handling of sodium, potassium, calcium and phosphate in man. J Clin Invest 1975;55:845-855.
3. 3. Rocchini AP, Katch V, Kveselis D, et al: Insulin and renal sodium retention in obese adolescents. Hypertension 1989;14:367-374.
4. 4. Rowe JW, Young JB, Miwaker KL, et al: Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man. Diabetes 1981;30:219-225.
5. 5. Trovati M, Massucco P, Anfossi G, et al: Insulin influences the renin-angiotensin-aldosterone system in humans. Metabolism 1989;6:501-503.
6. 6. Hall JE, Summers RL, Brands MW, et al: Resistance to metabolic actions of insulin and its role in hypertension. Am J Hypertens 1994;7:772-788.
7. 7. Tsutsu N, Nuadi K, Kodama T: Lack of association between blood pressure and insulin in patients with insulinoma. J Hypertens 1990;8:479-482.
8. 8. Baron AD: Hemodynamic actions of insulin. Am J Physiol 1994;30:E187-E202.
9. 9. Steinberg HO, Brechtel G, Johnson A, et al: Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J Clin Invest 1994;94:1172-1179.
10. 10. Cohen AJ, McCarthy DM, Stoff J: Direct hemodynamic effect on insulin in the isolated perfused kidney. Am J Physiol 1989;257:F580.
11. 11. Reikeras O, Gunnes P: Renal blood flow during acute ischaemic heart failure in dogs: effect of dopamine and high doses of insulin. Scand J Clin Lab Invest 1986; 46:671-675.
12. 12. Baron AD, Brechtel G, Johnson A, et al: Interactions between insulin and norepinephrine on blood pressure and insulin sensitivity. J Clin Invest 1994;93:2453-2462.
13. 13. Hirschberg RR, Kopple JD: Role of growth hormone in the aminoacid-induced acute rise in renal function in man. Kidney Int 1987;32:382-387.
14. 14. Castellino P, Giordano C, Perna A, et al: Effects of plasma aminoacid and hormone levels on renal hemodynamics in humans. Am J Physiol 1988;255:F444-F449.
15. 15. Moncada S, Palmer RMJ, Higgs EA: Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991;43:109-142.
16. 16. Palmer JP, Walter RM, Ensinck JW: Arginine stimulated acute phase of insulin and glucagon secretion. I. In normal man. Diabetes 1975;24:735-740.
17. 17. Laychock SG, Modica ME, Cavanaugh T: L-Arginine stimulates cyclic guanosine 3′,5′-monophosphate formation in rat islets of Langerhans and RINm5F insulinoma cells: evidence for L-arginine nitric oxide synthase. Endocrinology 1991;30:3043-3052.
18. 18. Villa E, Martinez J, Ruilope LM, et al: Cicaprost, a prostacyclin analog, protects renal function in uninephrectomized dogs in the absence of changes in blood pressure. Am J Hypertens 1993;6:253-257.
19. 19. Salmon MG, Lahera V, Romero JC: Role of prostaglandins and endothelium-derived relaxing factor on the renal response to acetylcholine. Am J Physiol 1991; 260:F145-F149.
20. 20. Opgenorth TJ, Granger JP, Chakravarty A, et al: Effect of intrarenal angiotensin-II infusion on the renal escape from mineralocorticoid. Am J Physiol 1985;145:F813-F818.
21. 21. Shen SW, Reaven GM, Farquhar JW: Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes. J Clin Invest 1970;49:1595-1607.
22. 22. Liedtke RR, Duarte CG: Laboratory protocols and methods for the measurement of glomerular filtration rate and renal plasma flow, in Duarte CG (ed): Renal Function Test: Clinical Laboratory Procedures and Diagnosis. Little, Brown & Company, Boston, 1980, pp 49-63.
23. 23. Ferranini E, Buzzigoli G, Bonadonna R, et al: Insulin resistence in essential hypertension. N Engl J Med. 1987;317:350-357.
24. 24. Sakai K, Imaizui T, Masaki H, et al: Intra-arterial infusion of insulin attenuates vasoreactivity in human forearm. Hypertension. 1993;22:67-73.
25. 25. Johnstone MT, Creager SJ, Scales KM, et al: Impaired endothelium-dependent vasodilatation in patients with insulin-dependent diabetes mellitus. Circulation. 1993;88:2510-2516.
26. 26. Gardiner SM, Compton AM, Bennett T, et al: Regional hemodynamic changes during oral ingestion of NG-monomethyl-L-arginine or NG-nitro-L-arginine methyl ester in conscious Brattleboro rats. Br J Pharmacol. 1990;101:10-12.
27. 27. Bredt DS, Hwang PM, Glatt C, et al: Cloned and expressed nitric oxide synthase structurally resembles cytochrome P450 reductase. Nature 1991;351:714-718.
28. 28. Lyons CR, Orloff GJ, Cunningham JM: Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J Biol Chem 1992;267:6370-6374.
29. 29. Lamas S, Marsdem PA, Li GK, et al: Endothelial nitric oxide synthase: molecular cloning and characterization of a distinct constitutive enzyme isoform. Proc Natl Acad Sci USA 1992;89:6348-6352.
30. 30. Geller DA, Lowenstein CJ, Shapiro RA, et al: Molecular cloning and expression of inducible nitric oxide synthase from human hepatocytes. Proc Natl Acad Sci USA 1993;90:3491-3495.
31. 31. Nishida K, Harrison DG, Navas JP, et al: Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase. J Clin Invest 1992;90:2092-2096.
32. 32. Schambelan M, Blake S, Sraer J, et al: Increased prostaglandin production by glomeruli isolated from rats with streptozoticin-induced diabetes. J Clin Invest 1985;75:404-412.
33. 33. Norryd C, Dencker H, Lunderquist A, et al: Superior mesenteric blood flow during digestion in man. Acta Chir Scand 1975;141:197-202.