Blockade of cardiac nicotinic responses by anticholinesterases

General Pharmacology

Volumn 27, Issue 5, 1996, Pages 861-872

  Paddle, Brian M ^a   Dowling, Margaret H ^a  

^a AERO AND MAR RESEARCH LABORATORY   (Australia)

Author keywords

Acetylcholine; Catecholamine release; Cholinesterase inhibitors; Edrophonium; Heart; Neostigmine; Nicotine; Nicotinic receptors; Physostigmine; Pyridostigmine; S oman; Tacrine

Indexed keywords

3,4 DIHYDROXYPHENYLETHYLENE GLYCOL; ACETYLCHOLINE; ATROPINE; CHOLINESTERASE INHIBITOR; EDROPHONIUM; NEOSTIGMINE; NICOTINE; NICOTINIC RECEPTOR; NORADRENALIN; PHYSOSTIGMINE; PYRIDINE NUCLEOTIDE; PYRIDOSTIGMINE; SOMAN; TACRINE;

ANIMAL TISSUE; ARTICLE; CHRONOTROPISM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; FEMALE; FLUORESCENCE; GUINEA PIG; HEART; HEART PERFUSION; HEART RIGHT ATRIUM; INOTROPISM; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; VASODILATATION;

EID: 0030198574     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-3623(95)02107-8     Document Type: Article

References (48)

1. Albuquerque E. X., Akaike A., Shaw K. P. and Rickett D. L. (1984) The inrefaction of anticholinesterase with the acetylcholine receptor-ionic channel complex. Fund. Appl. Toxicol. 4, S27-S33.
2. Albuquerque E. X., Aracava Y., Cintra W. M., Brossi A., Schonenberger B. and Deshpande S. S. (1988) Structure-activity relationship of reversible cholinesterase inhibitors: activation, channel blockade and stereospecificity of the nicotinic acetylcholine receptor-ion channel complex. Brazil. J. Med. Biol. Res. 21, 1173-1196.
3. Anton A. H. and Sayre D. F. (1962) A study of the factors affecting the aluminium oxide trihydroxyindole procedure for the analysis of catecholamines. J. Pharmac. Exp. Ther. 138, 360-375.
4. Bakry N. M. S., El-Rashidy A. H., Eldefrawi A. T. and Eldefrawi M. E. (1988) Direct actions of organophosphate anticholinesterases on nicotinic and muscarinic acetylcholine receptors. J. Biochem. Toxicol. 3, 235-259.
5. Berne R. M. (1963) Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. Am. J. Physiol. 204, 317-322.
6. Bowman W. C., Prior C. and Marshall I. G. (1990) Presynaptic receptors in the neuromuscular junction. Ann. NY Acad. Sci. 604, 69-81.
7. Brown J. H., Wetzel G. T. and Dunlap J. (1982) Activation and blockade of cardiac muscarinic receptors by endogenous acetylcholine and cholinesterase inhibitors. J. Pharmac. Exp. Ther. 223, 20-24.
8. Chance B., Williamson J. R., Jamieson D. and Schoener B. (1965) Properties and kinetics of reduced pyridine nucleotide fluorescence of the isolated and in vivo rat heart. Biochem. 2. 341, 357-377.
9. Chatonnet A. and Lockridge O. (1989) Comparison of butyrylcholinesterase and acetylcholinesterase. Biochem J. 260, 625-634.
10. Chiappinelli V. A. (1985) Actions of snake venom toxins on neuronal nicotinic receptors and other neuronal receptors. Pharmac. Ther. 31, 1-32.
11. Clarke P. B. S. (1989) Mapping of brain nicotinic receptors by autoradiographic techniques and the effect of experimental lesions. In Progress in Brain Research, Vol. 79 (Edited by Nordberg A., Fuxe K., Holmstedt B. and Sundwall A.), pp. 65-71. Elsevier, Amsterdam.
12. Clarke P. B. S., Reuben M. and El-Bizri H. (1994) Blockade of nicotinic responses by physostigmine, tacrine and other cholinesterase inhibitors in rat striatum. Br. J. Pharmac. 111, 695-702.
13. Dart A. M., Riemersma R. A., Schomig A. and Ungar A. (1987) Metabolic requirements for release of endogenous noradrenaline during myocardial ischaemia and anoxia. Br. J. Pharmac. 90, 43-50.
14. Feigl E. O. (1983) Coronary physiology. Physiol. Rev. 63, 1-205.
15. Fenton R. A. and Dobson J. G. (1985) Nicotine increases heart adenosine release, oxygen consumption, and contractility. Am. J. Physiol. 249, H463-H469.
16. Franco-Cereceda A., Saria A. and Lundberg J. M. (1989) Differential release of calcitonin gene-related peptide and neuropeptide Y from the isolated heart by capsaicin, ischaemia, nicotine, bradykinin and ouabain. Acta Physiol. Scand. 135, 173-187.
17. Freeman S. E. and Dawson R. M. (1991) Tacrine: a pharmacological review. Progr. Neurobiol 36, 257-277.
18. Freeman S. E., Dawson R. M. and Keegan A. M. (1986) Modification of the effects of muscarinic agonists by reversible and irreversible anticholinesterase compounds in the guinea pig atrium. J. Mol. Cell. Cordiol. 18, 231-239.
19. Gillis R. A, Flacke W., Garfield J. M. and Alper M. H. (1968) Actions of anticholinesterase agents upon ganglionic transmission in the dog. J. Pharmac. Exp. Ther. 163, 277-286.
20. Gray P. J. and Dawson R. M. (1987) Kinetic constants for the inhibition of eel and rabbit brain acetylcholinesterases by some organophosphates and carbamates of military significance. Toxicol. Appl. Pharmac. 91, 140-144.
21. Hunter A J., Murray T. K., Jones J. A, Cross A. J. and Green A. R. (1989) The cholinergic pharmacology of tetrahydroaminoacridine in vivo and in vitro. Br. J. Pharmac. 98, 79-86.
22. Irisawa H. and Noma A. (1986) Origin and regulation of cardiac rhythmicity. In Regulation of Heart Function, Basic Concepts and Clinical Applications (Edited by Rupp H.), pp. 95-105. Thieme, New York.
23. Lindmar R. and Löffelholtz K. (1990) The effect of tacrine on acetylcholine overflow in the heart. Eur. J. Pharmac. 190, 251-254.
24. Lindmar R., Löffelholtz K. and Muscholl E. (1968) A muscarinic mechanism inhibiting the release of noradrenaline from peripheral adrenergic nerve fibres by nicotinic agents. Br. J. Pharmac. 32, 280-294.
25. Loiacono R. E. and Mitchelson F. J. (1990) Effect of nicotine and tacrine on acetylcholine release from rat cerebral cortical slices. Naunyn-Schmiedeberg's Arch. Pharmac. 342, 31-35.
26. Marley P. D. (1988) Desensitizaton of the nicotinic secretory response of adrenal chromaffin cells. TIPS 9, 102-107.
27. Muscholl E. (1980) Review: peripheral muscarinic control of norepinephrine release in the cardiovascular system. Am. J. Physiol. 239, H713-H720.
28. Muscholl E. and Muth A. (1982) The effect of physostigmine on the vagally induced muscarinic inhibition of noradrenaline release from the isolated perfused rabbit atria. Naunyn-Schmiedeberg's Arch. Pharmac, 320, 160-169.
29. Nedergaard O. A. (1988) Effect of nicotine on neuroeffector transmission in blood vessels. In The Pharmacology of Nicotine (ICSU Press Symposium Series), Vol. 9 (Edited by Rand M. J. and Thurau K.), pp. 143-162. Oxford University Press, Oxford, UK.
30. Nuuitinen E. M., Wilson D. F. and Erecinska M. (1985) The effect of cholinergic agonists on coronary flow rate and oxygen consumption in isolated perfused rat heart. J. Mol. Cell. Cardiol. 17, 31-42.
31. Ochoa E. L. M., Chattopadhyay A. and McNamee M. G. (1989) Desensitization of the nicotinic acetylcholine receptor: molecular mechanisms and effect of modulators. Cell. Mol. Neurobiol. 9, 141-178.
32. Olsson R. A. and Pearson J. D. (1990) Cardiovascular purinoceptors. Physiol. Rev. 70, 761-845.
33. Osterrieder W. (1987) 9-Amino-1,2,3,4-tetrahydroacridine (THA) is a potent blocker of cardiac potassium channels. Br. J. Pharmac. 92, 521-525.
34. Paddle B. M. and Burnstock G. (1974) Release of ATP from perfused heart during coronary vasodilatation. Blood Vessels 11, 110-119.
35. Perry E. K., Smith C. J., Court J. A, Bonham J. R., Rodway M. and Atack J. R. (1988) Interaction of 9-amino-1,2,3,4-tetrahydroacndine (THA) with human cortical nicotinic and muscarinic receptor binding in vitro. Neurosci. Lett. 91, 211-216.
36. Richardt G., Hass M., Neeb S., Hock M., Lang R. E. and Schomig A. (1988) Nicotine-induced release of noradtenaline and neuropeptide Y in guinea pig heart. Klin. Wochenschr. 66 (suppl. 11), 21-27.
37. Rogowski M. A. (1987) Tetrahydroaminoacridine blocks voltage-dependent ion channels in hippocampal neurons. Eur. J. Pharmac. 142, 169-172.
38. Sadoshima J., Tokutomi N. and Akaike Nl. (1988) Effects of neostigmine and physostigmine on the acetylcholine receptor-ionophore complex in frog isolated sympathetic neurones. Br. J. Pharmac. 94, 620-624.
39. Schomig A., Fischer S., Kurtz T., Richardt G. and Schomig E. (1987) Non-exocytotic release of endogenous noradrenaline in the ischaemic and anoxic rat heart: mechanism and metabolic requirements. Circ. Res. 60, 194-205.
40. Sherby S. M., Eldefrawi A. T., Albuquerque E. X. and Eldefrawi M. E. (1985) Comparison of the actions of carbamate anticholinesterases on the nicotinic acetylcholine receptor. Mol. Pharmac. 27, 343-348.
41. Silveira C. L., Eldefrawi A. T. and Eldefrawi M. E. (1990) Putative M2 muscarinic receptors of rat heart have high affinity for organophosphorus anticholinesterases. Toxicoi. Appl. Pharmac. 103, 474-481.
42. Starke K. (1977) Regulation of noradrenaline release by presynaptic receptor systems. Rev. Physiol. Biochem. Pharmac. 77, 1-124.
43. Szarbadi E. (1977) A model of two functionally antagonistic receptor populations activated by the same agonist. J. Theor. Biol. 69, 101-112.
44. Tamura M., Hazeki O., Nioka S., and Chance B. (1989) In vivo study of tissue oxygen metabolism using optical and nuclear magnetic resonance spectroscopies, Annu. Rev. Physiol. 51, 813-834.
45. Thomsen T., Zendeh B., Fischer J. P. and Kewitz H. (1991) In vitro effects of various cholinesterase inhibitors on acetyl-and butyrylcholinesterase of healthy volunteers. Biochem. Pharmac. 41, 139-141.
46. Wennmalm A. (1977) Nicotine stimulates prostaglandin formation in the rabbit heart. Br. J. Pharmac. 59, 95-100.
47. Wonnacott S., Irons J., Lunt G. G., Rapier C. M. and Albuquerque E. X. (1988) Alpha-bungarotoxin and presynaptic nicotinic receptors: functional studies. In: Nicotinic Acetylcholine Receptors in the Nervous System (NATO ASI Series), Vol. H25 (Edited by Clementi F., Gotti C., and Sher E.), pp. 41-60. Springer, Berlin.
48. Yost C. S. and Maestrone E. (1994) Clinical concentrations of edrophonium enhance desensitization of the nicotinic acetylcholine receptor. Anesthes. Analg. 78, 520-526.