Synaptic alterations of anterior horn cells in Werdnig-Hoffmann disease

Pediatric Neurology

Volumn 15, Issue 1, 1996, Pages 32-35

  Yamanouchi, Yoko ^a,b   Yamanouchi, Hideo ^a   Becker, Laurence E ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTERIOR HORN CELL; ARTICLE; CLINICAL ARTICLE; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; INFANT; NERVE CELL DEGENERATION; NEWBORN; PRIORITY JOURNAL; SPINAL CORD; WERDNIG HOFFMANN DISEASE;

EID: 0030197991     PISSN: 08878994     EISSN: None     Source Type: Journal    
DOI: 10.1016/0887-8994(96)00123-3     Document Type: Article

References (25)

1. [1] Pearn JH. Infantile motor neuron diseases. In: Rowland LP, ed. Advances in neurology. New York: Raven Press, 1982;36:121-30.
2. [2] Carpenter S, Karpati G, Rothman S, Watters G, Andermann F. Pathological involvement of primary sensory neurons in Werdnig-Hoffmann disease. Acta Neuropathol (Berl) 1978;42:91-7.
3. [3] Iwata M, Hirano A. A neuropathological study of the Werdnig-Hoffmann disease. Neurol Med (Tokyo) 1978;8:40-53.
4. [4] Iwata M. Glial bundles of nerve roots in Werdnig-Hoffmann disease. Ann Neurol 1980;8:81-2.
5. [5] Shishikura K, Hara M, Sasaki Y, Misugi K. A neuropathologic study of Werdnig-Hoffmann disease with special reference to the thalamus and posterior roots. Acta Neuropathol (Berl) 1983;60:99-106.
6. [6] Steinman GS, Rorke LB, Brown MJ. Infantile neuronal degeneration masquerading as Werdnig-Hoffmann disease. Ann Neurol 1980; 8:317-24.
7. [7] Towfighi J, Young RSK, Ward RM. Is Werdnig-Hoffmann disease a pure lower motor neuron disease? Acta Neuropathol (Berl) 1985; 65:270-80.
8. [8] Peress NS, Stermann AB, Miller R, Kaplan CG, Little BW. "Chromatolytic" neurons in lateral geniculate body in Werdnig-Hoffmann disease. Clin Neuropathol 1986;5:69-72.
9. [9] Roy N, Mahadevan MS, McLean M, et al. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 1995;80:167-78.
10. [10] Lefebvre S, Bürglen L, Reboullet S, et al. Identification and characterization of a spinal muscular atrophy-determining gene. Cell 1995;80:155-65.
11. [11] Thompson TG, DiDonato CJ, Simard LR, et al. A novel cDNA detects homozygous microdeletions in greater than 50% of type I spinal muscular atrophy patients. Nature Genet 1995;9:56-62.
12. [12] Kawanami T, Ikemoto A, Llena JF, Hirano A. Synaptophysin immunoreactivity pattern in the anterior horn cells in amyotrophic lateral sclerosis (Abstract). Can J Neurol Sci 1993;20:75.
13. [13] Sasaki S, Maruyama S. Decreased synaptophysin immunoreactivity of the anterior horns in motor neuron disease. Acta Neuropathol 1994;87:125-8.
14. [14] Jahn R, Schiebler W, Ouiment C, Greengard P. A 38,000-dalton membrane protein (p 38) present in synaptic vesicles. Proc Natl Acad Sci USA 1985;82:4137-41.
15. [15] Navone F, Jahn R, DiGioia G, DiGioia G, Stukenbrok H, Greengard P. Protein p38: An integral protein specific for small vesicles of neurons and neuroendocrine cells. J Cell Biol 1986:103:2511-27.
16. [16] Rehm H, Wiedenmann B, Betz H. Molecular characterization of synaptophysin, a major calcium-binding protein of the presynaptic vesicle membrane. EMBO J 1986;5:535-41.
17. [17] Wiedenmann B, Franke WW. Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles. Cell 1985;41:1017-28.
18. [18] Gomez MR. Motor neuron diseases in children. In: Engel AG, Franzini-Armstrong C, eds. Myology. New York: McGraw-Hill, 1994: 1837-53.
19. [19] Lippa CF, Smith TW. Chromatolytic neurons in Werdnig-Hoffmann disease contain phosphorylated neurofilaments. Acta Neuropathol 1988;77:91-4.
20. [20] Murayama S, Bouldin TW, Suzuki K. Immunohistochemical and ultrastructural studies of Werdnig-Hoffmann disease. Acta Neuropathol 1991;81:408-17.
21. [21] Ikemoto A, Hirano A. Immunohistochemical study on synaptophysin expression in the anterior horn of Werdnig-Hoffmann disease (Abstract). Muscle Nerve 1994;17(suppl 1):S154.
22. [22] Ikemoto A, Kawanami T, Llena JF, Hirano A. Immunocytochemical studies on synaptophysin in the anterior horn of lower motor neuron disease. J Neuropathol Exp Neurol 1994;53:196-201.
23. [23] Scheff SW, Price DA. Synapse loss in the temporal lobe in Alzheimer's disease. Ann Neurol 1993;33:190-9.
24. [24] Rutledge LT. The effect of denervation and stimulation upon synaptic ultrastructure. J Comp Neurol 1978;178:117-28.
25. [25] Karpati G, Carpenter S, Durham H. A hypothesis for the pathogenesis of amyotrophic lateral sclerosis. Rev Neurol 1988;144:672-5.