메뉴 건너뛰기




Volumn 5, Issue 7, 1996, Pages 406-412

The P-450 System: Definition and Relevance to the Use of Antidepressants in Medical Practice

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CYTOCHROME P450;

EID: 0030188503     PISSN: 10633987     EISSN: None     Source Type: Journal    
DOI: 10.1001/archfami.5.7.406     Document Type: Review
Times cited : (10)

References (104)
  • 1
    • 0026750647 scopus 로고
    • The human hepatic cytochromes P450 involved in drug metabolism
    • Wrighton S, Stevens J. The human hepatic cytochromes P450 involved in drug metabolism. Crit Rev Toxicol. 1992;22:1-21.
    • (1992) Crit Rev Toxicol , vol.22 , pp. 1-21
    • Wrighton, S.1    Stevens, J.2
  • 2
    • 0026507870 scopus 로고
    • Human cytochrome, P-450 enzymes
    • Guengerich F. Human cytochrome, P-450 enzymes. Life Sci. 1992;50:1471-1478.
    • (1992) Life Sci , vol.50 , pp. 1471-1478
    • Guengerich, F.1
  • 3
    • 0024550760 scopus 로고
    • The P450 superfamily: Updated listing of all genes and recommended nomenclature for the chromosomal loci
    • Nebert D, Nelson D, Adesnik M. The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci. DNA Seq. 1989;8:1-13.
    • (1989) DNA Seq , vol.8 , pp. 1-13
    • Nebert, D.1    Nelson, D.2    Adesnik, M.3
  • 4
    • 0027446505 scopus 로고
    • The P450 superfamily: Update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature
    • Nelson D, Kamataki T, Wasman D. The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature. DNA Cell Biol. 1993;12:1-51.
    • (1993) DNA Cell Biol , vol.12 , pp. 1-51
    • Nelson, D.1    Kamataki, T.2    Wasman, D.3
  • 5
    • 0025323155 scopus 로고
    • Selectivity in the inhibition of mammalian cytochromes P450 by chemical agents
    • Murray M, Reidy G. Selectivity in the inhibition of mammalian cytochromes P450 by chemical agents. Pharmacol Rev. 1990;42:85-101.
    • (1990) Pharmacol Rev , vol.42 , pp. 85-101
    • Murray, M.1    Reidy, G.2
  • 6
    • 0027392759 scopus 로고
    • Influence of debrisoquine hydroxylation phenotype on the pharmacokinetics of mexiletine
    • Lledo P, Abrams S, Johnson A. Influence of debrisoquine hydroxylation phenotype on the pharmacokinetics of mexiletine. Eur J Clin Pharmacol. 1993;44:63-67.
    • (1993) Eur J Clin Pharmacol , vol.44 , pp. 63-67
    • Lledo, P.1    Abrams, S.2    Johnson, A.3
  • 7
    • 0022178173 scopus 로고
    • Interethnic difference in genetic polymorphism of debrisoquine and mephenytoin hydroxylation between Japanese and Caucasian populations
    • Nakamura K, Goto F, Ray W, McAllister C, Jacqz E, Wilkinson G. Interethnic difference in genetic polymorphism of debrisoquine and mephenytoin hydroxylation between Japanese and Caucasian populations. Clin Pharmacol Ther. 1985;38:402-408.
    • (1985) Clin Pharmacol Ther , vol.38 , pp. 402-408
    • Nakamura, K.1    Goto, F.2    Ray, W.3    McAllister, C.4    Jacqz, E.5    Wilkinson, G.6
  • 8
    • 0025269106 scopus 로고
    • Recent developments in hepatic drug oxidation: Implications for clinical pharmacokinetics
    • Brosen K. Recent developments in hepatic drug oxidation: implications for clinical pharmacokinetics. Clin Pharmacokinet. 1990;18:220-239.
    • (1990) Clin Pharmacokinet , vol.18 , pp. 220-239
    • Brosen, K.1
  • 9
    • 0021684926 scopus 로고
    • Mephenytoin hydroxylation deficiency in Caucasians: Frequency of a new oxidative drug metabolism polymorphism
    • Wedlund P, Aslanian W, McAllister C, Wilkinson G, Branch R. Mephenytoin hydroxylation deficiency in Caucasians: frequency of a new oxidative drug metabolism polymorphism. Clin Pharmacol Ther. 1984;36:773-780.
    • (1984) Clin Pharmacol Ther , vol.36 , pp. 773-780
    • Wedlund, P.1    Aslanian, W.2    McAllister, C.3    Wilkinson, G.4    Branch, R.5
  • 10
    • 0026879487 scopus 로고
    • Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites
    • Butler M, Lang N, Young J, et al. Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites. Pharmacogenetics. 1992;2: 116-127.
    • (1992) Pharmacogenetics , vol.2 , pp. 116-127
    • Butler, M.1    Lang, N.2    Young, J.3
  • 11
    • 0024336503 scopus 로고
    • S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquine
    • Sanz E, Villen T, Alm C, Bertilsson L. S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquine. Clin Pharmacol Ther. 1989;45:495-499.
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 495-499
    • Sanz, E.1    Villen, T.2    Alm, C.3    Bertilsson, L.4
  • 12
    • 0027923337 scopus 로고
    • Recent pharmacologic advances in antidepressant therapy for the elderly
    • Preskorn S. Recent pharmacologic advances in antidepressant therapy for the elderly. Am J Med. 1993;94(suppl 5A):2S-12S.
    • (1993) Am J Med , vol.94 , Issue.SUPPL. 5A
    • Preskorn, S.1
  • 13
    • 0024602703 scopus 로고
    • Pharmacokinetic and pharmacodynamic principles of drug therapy in old age: Part 2
    • Tsujimoto G, Hashimoto K, Hoffman B. Pharmacokinetic and pharmacodynamic principles of drug therapy in old age: part 2. Int J Clin Pharmacol Ther Toxicol. 1989;27:102-116.
    • (1989) Int J Clin Pharmacol Ther Toxicol , vol.27 , pp. 102-116
    • Tsujimoto, G.1    Hashimoto, K.2    Hoffman, B.3
  • 14
  • 17
    • 0025915325 scopus 로고
    • Fluoxetine and norfluoxetine are potent inhibitors of P450IID6: The source of the sparteine/debrisoquine oxidation polymorphism
    • Brosen K, Skejlbo E. Fluoxetine and norfluoxetine are potent inhibitors of P450IID6: the source of the sparteine/debrisoquine oxidation polymorphism. Br J Clin Pharmacol. 1991;32:136-137.
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 136-137
    • Brosen, K.1    Skejlbo, E.2
  • 18
    • 0026787192 scopus 로고
    • The effect of selective serotonin reuptake inhibitors on cytochrome P4502D6 (CYPD6) activity in human liver microsomes
    • Crewe H, Lennard M, Tucker G. The effect of selective serotonin reuptake inhibitors on cytochrome P4502D6 (CYPD6) activity in human liver microsomes. Br J Clin Pharmacol. 1992;34:262-265.
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 262-265
    • Crewe, H.1    Lennard, M.2    Tucker, G.3
  • 19
    • 0028898816 scopus 로고
    • Inhibition of aprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: Comparison with other selective serotonin reuptake inhibitor antidepressants
    • von Moltke L, Greenblatt D, Court M. Inhibition of aprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants. J Clin Psychopharmacol. 1995;15:125-131.
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 125-131
    • Von Moltke, L.1    Greenblatt, D.2    Court, M.3
  • 20
    • 0023788246 scopus 로고
    • Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes
    • Otton S, Crewe H, Lennard M, Tucker G, Woods H. Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes. J Pharmacol Exp Ther. 1988;247:242-247.
    • (1988) J Pharmacol Exp Ther , vol.247 , pp. 242-247
    • Otton, S.1    Crewe, H.2    Lennard, M.3    Tucker, G.4    Woods, H.5
  • 21
  • 22
    • 0342426140 scopus 로고
    • Coadministration of nefazodone and benzodiazepines, I: Pharmacokinetic assessment
    • Abstract
    • Greene D, Dockens R, Salazar D. Coadministration of nefazodone and benzodiazepines, I: pharmacokinetic assessment. Clin Pharmacol Ther. 1994;55:141. Abstract.
    • (1994) Clin Pharmacol Ther , vol.55 , pp. 141
    • Greene, D.1    Dockens, R.2    Salazar, D.3
  • 23
    • 0021049268 scopus 로고
    • Effects of macrolide antibiotics on drug metabolism in rats and humans
    • Pessayre D. Effects of macrolide antibiotics on drug metabolism in rats and humans. Int J Clin Pharmacol Res. 1983;111:449-458.
    • (1983) Int J Clin Pharmacol Res , vol.111 , pp. 449-458
    • Pessayre, D.1
  • 24
    • 0028343588 scopus 로고
    • Comparison of the effect of the macrolide antibiotics erythromycin, clarithromycin and azithromycin on terfenadine steady-state pharmacokinetics and electrocardiographic parameters
    • Honig P, Wortham D, Zamani K, Cantilena L. Comparison of the effect of the macrolide antibiotics erythromycin, clarithromycin and azithromycin on terfenadine steady-state pharmacokinetics and electrocardiographic parameters. Drug Invest. 1994;7:148-156.
    • (1994) Drug Invest , vol.7 , pp. 148-156
    • Honig, P.1    Wortham, D.2    Zamani, K.3    Cantilena, L.4
  • 25
    • 0020041376 scopus 로고
    • Drug metabolism by rat and human hepatic microsomes in response to interaction with H2-receptor antagonists
    • Knodell R, Holtzman J, Crankshaw D, Steele N, Stanley L. Drug metabolism by rat and human hepatic microsomes in response to interaction with H2-receptor antagonists. Gastroenterology. 1982;82:84-88.
    • (1982) Gastroenterology , vol.82 , pp. 84-88
    • Knodell, R.1    Holtzman, J.2    Crankshaw, D.3    Steele, N.4    Stanley, L.5
  • 26
    • 0027468346 scopus 로고
    • Terfenadine-ketoconazole interaction: Pharmacokinetic and electrocardiographic consequences
    • Honig P, Wortham D, Zamani K, Conner DP, Mullin JC, Cantilena LR. Terfenadine-ketoconazole interaction: pharmacokinetic and electrocardiographic consequences. JAMA. 1993;269:1513-1518.
    • (1993) JAMA , vol.269 , pp. 1513-1518
    • Honig, P.1    Wortham, D.2    Zamani, K.3    Conner, D.P.4    Mullin, J.C.5    Cantilena, L.R.6
  • 27
    • 0027385194 scopus 로고
    • Syncope and cardiac arrhythmia due to an interaction between itraconazole and terfenadine
    • Crane J, Shih H-T. Syncope and cardiac arrhythmia due to an interaction between itraconazole and terfenadine. Am J Med. 1993;95: 445-446.
    • (1993) Am J Med , vol.95 , pp. 445-446
    • Crane, J.1    Shih, H.-T.2
  • 28
    • 0025893763 scopus 로고
    • Interaction between cyclosporine and fluconazole in renal allograft recipients
    • Canafax D, Graves N, Hilligoes D. Interaction between cyclosporine and fluconazole in renal allograft recipients. Transplantation. 1991;51: 1014-1018.
    • (1991) Transplantation , vol.51 , pp. 1014-1018
    • Canafax, D.1    Graves, N.2    Hilligoes, D.3
  • 29
    • 0028211190 scopus 로고
    • Possible interaction of sertraline with carbamazepine
    • Joblin M. Possible interaction of sertraline with carbamazepine. N Z Med J. 1994;107:43.
    • (1994) N Z Med J , vol.107 , pp. 43
    • Joblin, M.1
  • 31
    • 0023906457 scopus 로고
    • The effect of fluoxetine on the pharmacokinetics and psychomotor responses of diazepam
    • Lemberger L, Rowe H, Bosomworth J, Tenbarge J, Bergstrom R. The effect of fluoxetine on the pharmacokinetics and psychomotor responses of diazepam. Clin Pharmacol Ther. 1988;43:412-419.
    • (1988) Clin Pharmacol Ther , vol.43 , pp. 412-419
    • Lemberger, L.1    Rowe, H.2    Bosomworth, J.3    Tenbarge, J.4    Bergstrom, R.5
  • 32
    • 0025760457 scopus 로고
    • Pharmacokinetic and pharmacodynamic evaluation of the combined administration of alprazolam and fluoxetine
    • Lasher T, Fleishaker J, Steenwyck R, Antal E. Pharmacokinetic and pharmacodynamic evaluation of the combined administration of alprazolam and fluoxetine. Psychopharmacology (Berl). 1991;104:323-327.
    • (1991) Psychopharmacology (Berl) , vol.104 , pp. 323-327
    • Lasher, T.1    Fleishaker, J.2    Steenwyck, R.3    Antal, E.4
  • 33
    • 0025788860 scopus 로고
    • Increased carbamazepine plasma concentrations after fluoxetine coadministration
    • Grimsley S, Jann M, Carter J. Increased carbamazepine plasma concentrations after fluoxetine coadministration. Clin Pharmacol Ther. 1991;50:10-15.
    • (1991) Clin Pharmacol Ther , vol.50 , pp. 10-15
    • Grimsley, S.1    Jann, M.2    Carter, J.3
  • 34
    • 0027489145 scopus 로고
    • Potential terfenadine-fluoxetine interaction
    • Swims M. Potential terfenadine-fluoxetine interaction. Ann Pharmacother. 1993;27:1404-1405.
    • (1993) Ann Pharmacother , vol.27 , pp. 1404-1405
    • Swims, M.1
  • 35
    • 0027406654 scopus 로고
    • Fluvoxamine is a potent inhibitor of cytochrome P4501A2
    • Brosen K, Skjelbo E, Rasmussen B. Fluvoxamine is a potent inhibitor of cytochrome P4501A2. Biochem Pharmacol. 1993;45:1211-1214.
    • (1993) Biochem Pharmacol , vol.45 , pp. 1211-1214
    • Brosen, K.1    Skjelbo, E.2    Rasmussen, B.3
  • 36
    • 0026718146 scopus 로고
    • Inhibitory potency of quinolone antibacterial agents against cytochrome P4501A2 activity in vivo and in vitro
    • Fuhr U, Anders E, Mahr G. Inhibitory potency of quinolone antibacterial agents against cytochrome P4501A2 activity in vivo and in vitro. Antimicrob Agents Chemother. 1992;36:942-948.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 942-948
    • Fuhr, U.1    Anders, E.2    Mahr, G.3
  • 37
    • 0026579126 scopus 로고
    • Toxic reaction following the combined administration of fluoxetine and phenytoin: Two case reports
    • Jalil P. Toxic reaction following the combined administration of fluoxetine and phenytoin: two case reports. J Neurol Neurosurg Psychiatry. 1992;55:412-413.
    • (1992) J Neurol Neurosurg Psychiatry , vol.55 , pp. 412-413
    • Jalil, P.1
  • 38
  • 39
    • 23444454167 scopus 로고
    • Fluoxetine labeling revised to identify phenytoin interaction and to recommend against use in nursing mothers
    • Nightingale S. Fluoxetine labeling revised to identify phenytoin interaction and to recommend against use in nursing mothers. JAMA. 1994; 271:1067.
    • (1994) JAMA , vol.271 , pp. 1067
    • Nightingale, S.1
  • 40
    • 0026795695 scopus 로고
    • Inhibitors of imipramine metabolism by human liver microsomes
    • Skejelbo E, Brosen K. Inhibitors of imipramine metabolism by human liver microsomes. Br J Clin Pharmacol. 1992;34:256-261.
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 256-261
    • Skejelbo, E.1    Brosen, K.2
  • 41
    • 0026568846 scopus 로고
    • The role of cytochrome P4502D6 in the metabolism of paroxetine by human liver microsomes
    • Bloomer J, Woods F, Haddock R. The role of cytochrome P4502D6 in the metabolism of paroxetine by human liver microsomes. Br J Clin Pharmacol. 1992;25:521-523.
    • (1992) Br J Clin Pharmacol , vol.25 , pp. 521-523
    • Bloomer, J.1    Woods, F.2    Haddock, R.3
  • 42
    • 0027456438 scopus 로고
    • Inhibition by fluoxetine of cytochrome P4502D6 activity
    • Otton S. Inhibition by fluoxetine of cytochrome P4502D6 activity. Clin Pharmacol Ther. 1993;53:401-409.
    • (1993) Clin Pharmacol Ther , vol.53 , pp. 401-409
    • Otton, S.1
  • 43
    • 0027375143 scopus 로고
    • Pharmacokinetics of antidepressants: Why and how they are relevant to treatment
    • Preskorn S. Pharmacokinetics of antidepressants: why and how they are relevant to treatment. J Clin Psychiatry. 1993;54(suppl 9):14-34.
    • (1993) J Clin Psychiatry , vol.54 , Issue.9 SUPPL. , pp. 14-34
    • Preskorn, S.1
  • 44
    • 0024205156 scopus 로고
    • Fluoxetine induced elevation of desipramine levels and exacerbation of geriatric nonpsychotic depression
    • Bell I, Cole J. Fluoxetine induced elevation of desipramine levels and exacerbation of geriatric nonpsychotic depression. J Clin Psychopharmacol. 1988;8:447-448.
    • (1988) J Clin Psychopharmacol , vol.8 , pp. 447-448
    • Bell, I.1    Cole, J.2
  • 45
    • 0027191034 scopus 로고
    • Interactions between sertraline and tricyclic antidepressants
    • Lydiard R, Anton R, Cunningham T. Interactions between sertraline and tricyclic antidepressants. Am J Psychiatry. 1993;150:1125-1126.
    • (1993) Am J Psychiatry , vol.150 , pp. 1125-1126
    • Lydiard, R.1    Anton, R.2    Cunningham, T.3
  • 46
    • 0026478902 scopus 로고
    • Tricyclic antidepressant plasma levels after fluoxetine addition
    • Vandel S, Bertschy G, Bonin B. Tricyclic antidepressant plasma levels after fluoxetine addition. Neuropsychobiology. 1992;25:202-207.
    • (1992) Neuropsychobiology , vol.25 , pp. 202-207
    • Vandel, S.1    Bertschy, G.2    Bonin, B.3
  • 47
    • 0026666628 scopus 로고
    • Introduction of a composite parameter to the pharmacokinetics of venlafaxine and its active O-desmethyl metabolite
    • Klamerus K, Maloney K, Rudolph R, Sisenwine S, Jusko W, Chiang S. Introduction of a composite parameter to the pharmacokinetics of venlafaxine and its active O-desmethyl metabolite. J Clin Pharmacol. 1992;32:716-724.
    • (1992) J Clin Pharmacol , vol.32 , pp. 716-724
    • Klamerus, K.1    Maloney, K.2    Rudolph, R.3    Sisenwine, S.4    Jusko, W.5    Chiang, S.6
  • 48
    • 1842506491 scopus 로고
    • More about spontaneous post marketing reports of bupropion-related seizures
    • Rosenblatt J, Rosenblatt N. More about spontaneous post marketing reports of bupropion-related seizures. Curr Affect Illness. 1992;11:18-20.
    • (1992) Curr Affect Illness , vol.11 , pp. 18-20
    • Rosenblatt, J.1    Rosenblatt, N.2
  • 49
    • 0025730148 scopus 로고
    • Elevation of plasma concentrations of haloperidol after the addition of fluoxetine
    • Goff D, Midha K, Brotman A. Elevation of plasma concentrations of haloperidol after the addition of fluoxetine. Am J Psychiatry. 1991;148: 790-792.
    • (1991) Am J Psychiatry , vol.148 , pp. 790-792
    • Goff, D.1    Midha, K.2    Brotman, A.3
  • 50
    • 0026692983 scopus 로고
    • Haloperidol disposition is dependent on debrisoquine hydroxylation phenotype
    • Llerena A, Alm C, Dahl M, Ekqvist B, Bertilsson L. Haloperidol disposition is dependent on debrisoquine hydroxylation phenotype. Ther Drug Monit 1992;14:92-97.
    • (1992) Ther Drug Monit , vol.14 , pp. 92-97
    • Llerena, A.1    Alm, C.2    Dahl, M.3    Ekqvist, B.4    Bertilsson, L.5
  • 52
    • 0026086815 scopus 로고
    • Plasma levels of thioridazine and metabolites are influenced by the debrisoquin hydroxylation phenotype
    • von Bahr C, Movin G, Nordin C, et al. Plasma levels of thioridazine and metabolites are influenced by the debrisoquin hydroxylation phenotype. Clin Pharmacol Ther. 1991;49:234-240.
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 234-240
    • Von Bahr, C.1    Movin, G.2    Nordin, C.3
  • 54
    • 0026666976 scopus 로고
    • The antipsychotic clozapine is metabolized by the polymorphic human microsomal cytochrome P4502D6
    • Fisher V, Vogels B, Maurer G, Tynes R. The antipsychotic clozapine is metabolized by the polymorphic human microsomal cytochrome P4502D6. J Pharmacol Exp Ther. 1992;260:1355-1360.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 1355-1360
    • Fisher, V.1    Vogels, B.2    Maurer, G.3    Tynes, R.4
  • 55
    • 0026472355 scopus 로고
    • Polymorphism of dextromethorphan metabolism: Relationships between phenotype, genotype and response to the administration of encainide in humans
    • Funck-Brentano C, Thomas G, Jacqa-Aigrain E. Polymorphism of dextromethorphan metabolism: relationships between phenotype, genotype and response to the administration of encainide in humans. J Pharmacol Exp Ther. 1992;263:780.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 780
    • Funck-Brentano, C.1    Thomas, G.2    Jacqa-Aigrain, E.3
  • 56
    • 0025312448 scopus 로고
    • The role of genetically determined polymorphic drug metabolism in the beta-blockade produced by propafenone
    • Lee J, Kroemer H, Silberstein D, et al. The role of genetically determined polymorphic drug metabolism in the beta-blockade produced by propafenone. N Engl J Med. 1990;322:1764-1768.
    • (1990) N Engl J Med , vol.322 , pp. 1764-1768
    • Lee, J.1    Kroemer, H.2    Silberstein, D.3
  • 57
    • 0020409410 scopus 로고
    • Oxidation phenotype: A major determinant of metoprolol metabolism and response
    • Lennard M, Silas J, Freestone S, et al. Oxidation phenotype: a major determinant of metoprolol metabolism and response. N Engl J Med. 1982;307:1558-1560.
    • (1982) N Engl J Med , vol.307 , pp. 1558-1560
    • Lennard, M.1    Silas, J.2    Freestone, S.3
  • 58
    • 0023884310 scopus 로고
    • Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation
    • Dayer P, Desmeules J, Leemann T, Striberni R. Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation. Biochem Biophys Res Commun. 1988;152:411-416.
    • (1988) Biochem Biophys Res Commun , vol.152 , pp. 411-416
    • Dayer, P.1    Desmeules, J.2    Leemann, T.3    Striberni, R.4
  • 59
    • 0025649038 scopus 로고
    • Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine
    • Sindrup S, Brosen K, Bjerring P, et al. Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine. Clin Pharmacol Ther. 1990; 48:686-693.
    • (1990) Clin Pharmacol Ther , vol.48 , pp. 686-693
    • Sindrup, S.1    Brosen, K.2    Bjerring, P.3
  • 60
    • 0025314857 scopus 로고
    • Interaction of fluoxetine and pentazocine
    • Hansen T. Interaction of fluoxetine and pentazocine. Am J Psychiatry. 1990;147:949-950.
    • (1990) Am J Psychiatry , vol.147 , pp. 949-950
    • Hansen, T.1
  • 61
    • 0029059649 scopus 로고
    • Pharmacokinetics of dextromethorphan and metabolites in humans: Influence of the CYP2D6 phenotype and quinidine inhibition
    • Schadel M, Wu D, Otton S, Kalow W, Sellers E. Pharmacokinetics of dextromethorphan and metabolites in humans: influence of the CYP2D6 phenotype and quinidine inhibition. J Clin Psychopharmacol. 1995;15:263-269.
    • (1995) J Clin Psychopharmacol , vol.15 , pp. 263-269
    • Schadel, M.1    Wu, D.2    Otton, S.3    Kalow, W.4    Sellers, E.5
  • 63
    • 0028194864 scopus 로고
    • Inhibition of desipramine hydoxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: A model system to predict drug interactions in vivo
    • von Moltke L, Greenblatt DJ, Cotreau-Bibbo M, Duan S, Hamartz J, Shader R. Inhibition of desipramine hydoxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: a model system to predict drug interactions in vivo. Pharmacol Exp Ther. 1994;268:1278-1283.
    • (1994) Pharmacol Exp Ther , vol.268 , pp. 1278-1283
    • Von Moltke, L.1    Greenblatt, D.J.2    Cotreau-Bibbo, M.3    Duan, S.4    Hamartz, J.5    Shader, R.6
  • 64
    • 1842558737 scopus 로고
    • Titusville, NJ: Janssen Pharmaceutica Inc
    • Propulsid [product insert]. Titusville, NJ: Janssen Pharmaceutica Inc; 1995.
    • (1995) Propulsid [Product Insert]
  • 65
    • 0027230584 scopus 로고
    • Major pathway of imipramine metabolism is catalyzed by cytochromes P4501A2 and P4503A4 in human liver
    • Lemoine A, Gauthier J, Azoulay D. Major pathway of imipramine metabolism is catalyzed by cytochromes P4501A2 and P4503A4 in human liver. Mol Pharmacol. 1993;43:827-832.
    • (1993) Mol Pharmacol , vol.43 , pp. 827-832
    • Lemoine, A.1    Gauthier, J.2    Azoulay, D.3
  • 66
    • 0022998708 scopus 로고
    • Characterization of rat and human liver microsomal cytochrome P450 forms involved in nifedipine oxidation: A prototype for genetic polymorphism in oxidative drug metabolism
    • Guengerich F, Martin M, Beaune P. Characterization of rat and human liver microsomal cytochrome P450 forms involved in nifedipine oxidation: a prototype for genetic polymorphism in oxidative drug metabolism. J Biol Chem. 1986; 261:5051-5060.
    • (1986) J Biol Chem , vol.261 , pp. 5051-5060
    • Guengerich, F.1    Martin, M.2    Beaune, P.3
  • 67
    • 0025168996 scopus 로고
    • Identification of the rabbit and human cytochrome P-450 IIIA as the major enzymes involved in the N-demethylation of diltiazem
    • Prichard L, Gillet G, Fabre I, et al. Identification of the rabbit and human cytochrome P-450 IIIA as the major enzymes involved in the N-demethylation of diltiazem. Drug Metab Dispos. 1990;18:711-719.
    • (1990) Drug Metab Dispos , vol.18 , pp. 711-719
    • Prichard, L.1    Gillet, G.2    Fabre, I.3
  • 69
    • 0028670421 scopus 로고
    • Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes
    • Mani C, Pearce R, Parkinson A. Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes. Carcinogenesis. 1994; 15:2716-2720.
    • (1994) Carcinogenesis , vol.15 , pp. 2716-2720
    • Mani, C.1    Pearce, R.2    Parkinson, A.3
  • 70
    • 0028300816 scopus 로고
    • Human liver carbamazepine metabolism: Roles of CYP3A4 and CYP2C8 in 10, 11 epoxide formation
    • Kerr B, Thummel K, Wurden C. Human liver carbamazepine metabolism: roles of CYP3A4 and CYP2C8 in 10, 11 epoxide formation. Biochem Pharmacol. 1994;47:1968-1979.
    • (1994) Biochem Pharmacol , vol.47 , pp. 1968-1979
    • Kerr, B.1    Thummel, K.2    Wurden, C.3
  • 71
    • 0025217803 scopus 로고
    • Cyclosporin metabolism in human liver microsomes and its inhibition by other drugs
    • Henricsson S, Lindholm A, Aravogolou M. Cyclosporin metabolism in human liver microsomes and its inhibition by other drugs. Pharmacol Toxicol. 1990;66:49-52.
    • (1990) Pharmacol Toxicol , vol.66 , pp. 49-52
    • Henricsson, S.1    Lindholm, A.2    Aravogolou, M.3
  • 72
    • 0023929834 scopus 로고
    • Human liver microsomal steroid metabolism: Identification of the major microsomal steroid hormone 6B-hydoxylase cytochrome P450 enzyme
    • Waxman D, Attisano C, Guengerich F, Lapenson D. Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6B-hydoxylase cytochrome P450 enzyme. Arch Biochem Biophys. 1988;263:424-436.
    • (1988) Arch Biochem Biophys , vol.263 , pp. 424-436
    • Waxman, D.1    Attisano, C.2    Guengerich, F.3    Lapenson, D.4
  • 73
    • 0028096880 scopus 로고
    • Recent developments in drug metabolism of relevance to psychiatrists
    • Pollak B. Recent developments in drug metabolism of relevance to psychiatrists. Harvard Rev Psychiatry. 1994;2:204-213.
    • (1994) Harvard Rev Psychiatry , vol.2 , pp. 204-213
    • Pollak, B.1
  • 74
    • 0027326229 scopus 로고
    • Alprazolam metabolism in vitro: Studies of human, monkey, mouse, and rat liver microsomes
    • von Moltke L, Greenblatt D, Harmatz J, Shader R. Alprazolam metabolism in vitro: studies of human, monkey, mouse, and rat liver microsomes. Pharmacology. 1993;47:268-276.
    • (1993) Pharmacology , vol.47 , pp. 268-276
    • Von Moltke, L.1    Greenblatt, D.2    Harmatz, J.3    Shader, R.4
  • 75
    • 0024373348 scopus 로고
    • Oxidation of midazolam and triazolam by human cytochrome P450IIIA4
    • Kronbach T, Mathys D, Umeno M. Oxidation of midazolam and triazolam by human cytochrome P450IIIA4. Mol Pharmacol. 1989;36:89-96.
    • (1989) Mol Pharmacol , vol.36 , pp. 89-96
    • Kronbach, T.1    Mathys, D.2    Umeno, M.3
  • 76
    • 0028568243 scopus 로고
    • Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole
    • Varhe A, Olkkola K, Neuvonen P. Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole. Clin Pharmacol Ther. 1994;56:601-607.
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 601-607
    • Varhe, A.1    Olkkola, K.2    Neuvonen, P.3
  • 77
    • 0028080304 scopus 로고
    • Inhibition of diazepam metabolism by fluvoxamine: A pharmacokinetic study in normal volunteers
    • Perucca E, Gatti G, Cipolla G, et al. Inhibition of diazepam metabolism by fluvoxamine: a pharmacokinetic study in normal volunteers. Clin Pharmacol Ther. 1994;56:471-476.
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 471-476
    • Perucca, E.1    Gatti, G.2    Cipolla, G.3
  • 78
    • 1842610828 scopus 로고
    • Effect of fluvoxamine on the pharmacokinetics and phrmacodynamics of alprazolam in healthy volunteers
    • Fleishaker J, Hulst L. Effect of fluvoxamine on the pharmacokinetics and phrmacodynamics of alprazolam in healthy volunteers. Pharm Res. 1992;9(suppl):S292.
    • (1992) Pharm Res , vol.9 , Issue.SUPPL.
    • Fleishaker, J.1    Hulst, L.2
  • 80
    • 0028150994 scopus 로고
    • Coadministration of fluvoxamine increases serum concentrations of haloperidol
    • Daniel D, Randolph C, Jaskiw G, et al. Coadministration of fluvoxamine increases serum concentrations of haloperidol. J Clin Psychopharmacol. 1994;14:340-343.
    • (1994) J Clin Psychopharmacol , vol.14 , pp. 340-343
    • Daniel, D.1    Randolph, C.2    Jaskiw, G.3
  • 81
    • 1842558731 scopus 로고
    • Morris Plains, NJ: Parke-Davis
    • Cognex [product monograph]. Morris Plains, NJ: Parke-Davis; 1993.
    • (1993) Cognex [Product Monograph]
  • 82
    • 0023687412 scopus 로고
    • A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-demethylation of phenacetin and is inducible by cigarette smoking
    • Sesardic D, Boobis A, Edwards R. A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-demethylation of phenacetin and is inducible by cigarette smoking. Br J Clin Pharmacol. 1988;26:363-372.
    • (1988) Br J Clin Pharmacol , vol.26 , pp. 363-372
    • Sesardic, D.1    Boobis, A.2    Edwards, R.3
  • 83
    • 0023113788 scopus 로고
    • Biotransformation of caffeine, paraxanthine, theophylline and theobromine by polycyclic aromatic hydrocarboninducible cytochrome P450 in human liver microsomes
    • Campbell M, Grant D, Inaba T. Biotransformation of caffeine, paraxanthine, theophylline and theobromine by polycyclic aromatic hydrocarboninducible cytochrome P450 in human liver microsomes. Drug Metab Dispos. 1987;15:237-248.
    • (1987) Drug Metab Dispos , vol.15 , pp. 237-248
    • Campbell, M.1    Grant, D.2    Inaba, T.3
  • 84
    • 0022467827 scopus 로고
    • Fluvoxamine: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness
    • Benfield P, Ward A. Fluvoxamine: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness. Drugs. 1986;32:313-334.
    • (1986) Drugs , vol.32 , pp. 313-334
    • Benfield, P.1    Ward, A.2
  • 85
    • 0027464837 scopus 로고
    • Clinical pharmacokinetics of selective serotonin reuptake inhibitors
    • Van Harten J. Clinical pharmacokinetics of selective serotonin reuptake inhibitors. Clin Pharmacokinetics. 1993;24:203-220.
    • (1993) Clin Pharmacokinetics , vol.24 , pp. 203-220
    • Van Harten, J.1
  • 86
    • 0028120975 scopus 로고
    • Probable metabolic interaction between methadone and fluvoxamine in addicted patients
    • Bertschy G. Probable metabolic interaction between methadone and fluvoxamine in addicted patients. Ther Drug Monit. 1994;16:42-45.
    • (1994) Ther Drug Monit , vol.16 , pp. 42-45
    • Bertschy, G.1
  • 87
    • 0028603653 scopus 로고
    • Pharmacogenetics and drug metabolism of newer antidepressant agents
    • DeVane L. Pharmacogenetics and drug metabolism of newer antidepressant agents. J Clin Psychiatry. 1994;55:38-45.
    • (1994) J Clin Psychiatry , vol.55 , pp. 38-45
    • DeVane, L.1
  • 88
    • 0028279041 scopus 로고
    • Evidence that CYPsC19 is the major (s)-mephenytoin 4′-hydroxylase in humans
    • Goldstein JA, Faletto MB, Romkes-Sparks M, et al. Evidence that CYPsC19 is the major (s)-mephenytoin 4′-hydroxylase in humans. Biochemistry. 1994;33:1743-1752.
    • (1994) Biochemistry , vol.33 , pp. 1743-1752
    • Goldstein, J.A.1    Faletto, M.B.2    Romkes-Sparks, M.3
  • 89
    • 0024580554 scopus 로고
    • Importance of genetic factors in the regulation of diazepam metabolism: Relationship to S-mephenytoin, but not debrisoquine, hydroxylation phenotype
    • Bertilsson L, Hentorn T, Sanz E, Tybring G, Säwe J, Villen T. Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquine, hydroxylation phenotype. Clin Pharmacol Ther. 1989;45:348-355.
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 348-355
    • Bertilsson, L.1    Hentorn, T.2    Sanz, E.3    Tybring, G.4    Säwe, J.5    Villen, T.6
  • 90
  • 91
    • 0024534047 scopus 로고
    • Propranolol's metabolism is determined by both mephytoin and debrisoquine hydroxylase activities
    • Wart SA, Walle T, Walle U, Wilkinson GR, Branch R. Propranolol's metabolism is determined by both mephytoin and debrisoquine hydroxylase activities. Clin Pharmacol Ther. 1989;45:72-79.
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 72-79
    • Wart, S.A.1    Walle, T.2    Walle, U.3    Wilkinson, G.R.4    Branch, R.5
  • 92
    • 0023355128 scopus 로고
    • Hepatic metabolism of tolbutamide: Characterization of the form of cytochrome P-450 involved in methyl hydroxylation and relationship to in vivo disposition
    • Knodell RG, Hall SD, Wilkinson GR, Guengerich F. Hepatic metabolism of tolbutamide: characterization of the form of cytochrome P-450 involved in methyl hydroxylation and relationship to in vivo disposition. J Pharmacol Exp Ther. 1987;241:1112-1119.
    • (1987) J Pharmacol Exp Ther , vol.241 , pp. 1112-1119
    • Knodell, R.G.1    Hall, S.D.2    Wilkinson, G.R.3    Guengerich, F.4
  • 93
    • 0026459382 scopus 로고
    • Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes
    • Smith D, Jones B. Speculations on the substrate structure-activity relationship (SSAR) of cytochrome P450 enzymes. Biochem Pharmacol. 1992;44:2089-2098.
    • (1992) Biochem Pharmacol , vol.44 , pp. 2089-2098
    • Smith, D.1    Jones, B.2
  • 94
    • 0027466151 scopus 로고
    • Drug interactions of clinical significance with opioid analgesics
    • Maurer PM, Bartkowski RB. Drug interactions of clinical significance with opioid analgesics, Drug Saf. 1993;8:30-48.
    • (1993) Drug Saf , vol.8 , pp. 30-48
    • Maurer, P.M.1    Bartkowski, R.B.2
  • 95
    • 0027474601 scopus 로고
    • Mechanism of the cardiotoxic action of terfenadine
    • Woolsey R, Chen Y, Freiman J, Gillis RA. Mechanism of the cardiotoxic action of terfenadine. JAMA. 1993;269:1532-1539.
    • (1993) JAMA , vol.269 , pp. 1532-1539
    • Woolsey, R.1    Chen, Y.2    Freiman, J.3    Gillis, R.A.4
  • 96
    • 0025222965 scopus 로고
    • Torsades de pointes occurring in association with terfenadine use
    • Monahan B, Ferguson C, Killeavy E. Torsades de pointes occurring in association with terfenadine use. JAMA. 1990;264:2788-2790.
    • (1990) JAMA , vol.264 , pp. 2788-2790
    • Monahan, B.1    Ferguson, C.2    Killeavy, E.3
  • 97
    • 0028158457 scopus 로고
    • Heart block in a patient on propranolol and fluoxetine
    • Drake W, Gordon G. Heart block in a patient on propranolol and fluoxetine. Lancet. 1994; 343:425-426.
    • (1994) Lancet , vol.343 , pp. 425-426
    • Drake, W.1    Gordon, G.2
  • 99
    • 0026519541 scopus 로고
    • Hydroxylation of warfarin by human cDNA-depressed cytochrome P-450: A role for P4502C9 in the etiology of (s)-warfarin-drug interactions
    • Rettie AE, Korzekwa KR, Kunze KL, et al. Hydroxylation of warfarin by human cDNA-depressed cytochrome P-450: a role for P4502C9 in the etiology of (s)-warfarin-drug interactions. Chem Res Toxicol. 1992;5:54-59.
    • (1992) Chem Res Toxicol , vol.5 , pp. 54-59
    • Rettie, A.E.1    Korzekwa, K.R.2    Kunze, K.L.3
  • 100
    • 0023616982 scopus 로고
    • An evaluation of population pharmacokinetics in therapeutic trials, II: Detection of a drug-drug interaction
    • Grasela T, Antal E, Ereshefsky L. An evaluation of population pharmacokinetics in therapeutic trials, II: detection of a drug-drug interaction. Clin Pharmacol Ther. 1987;42:433-441.
    • (1987) Clin Pharmacol Ther , vol.42 , pp. 433-441
    • Grasela, T.1    Antal, E.2    Ereshefsky, L.3
  • 101
    • 0028348762 scopus 로고
    • Pharmacokinetics of desipramine coadministered with sertraline or fluoxetine
    • Preskorn S, Alderman J, Chung M. Pharmacokinetics of desipramine coadministered with sertraline or fluoxetine. J Clin Psychopharmacol. 1994; 14:90-98.
    • (1994) J Clin Psychopharmacol , vol.14 , pp. 90-98
    • Preskorn, S.1    Alderman, J.2    Chung, M.3
  • 102
    • 0000223179 scopus 로고
    • Drug interaction between sertraline and desipramine or imipramine
    • Abstract
    • Kurtz D, Bergstrom R, Goldberg M, Cerimale B. Drug interaction between sertraline and desipramine or imipramine. J Clin Pharmacol. 1994; 34:1009-1033. Abstract.
    • (1994) J Clin Pharmacol , vol.34 , pp. 1009-1033
    • Kurtz, D.1    Bergstrom, R.2    Goldberg, M.3    Cerimale, B.4
  • 103
    • 0029918465 scopus 로고    scopus 로고
    • Absence of a sertraline-mediated effect on the pharmacokinetics and pharmacodynamics of carbamazepine
    • Rapeport W, Williams S, Muirhead D, Dewland P, Tanner T, Wesnes K. Absence of a sertraline-mediated effect on the pharmacokinetics and pharmacodynamics of carbamazepine. J Clin Psychiatry. 1996;57(suppl 1):20-23.
    • (1996) J Clin Psychiatry , vol.57 , Issue.1 SUPPL. , pp. 20-23
    • Rapeport, W.1    Williams, S.2    Muirhead, D.3    Dewland, P.4    Tanner, T.5    Wesnes, K.6
  • 104
    • 0030002395 scopus 로고    scopus 로고
    • Absence of effect of sertraline on the phamacokinetics and pharmacodynamics of phenytoin
    • Rapeport W, Muirhead D, Williams S, Cross M, Wesnes K. Absence of effect of sertraline on the phamacokinetics and pharmacodynamics of phenytoin. J Clin Psychiatry. 1996;57(suppl 1):24-28.
    • (1996) J Clin Psychiatry , vol.57 , Issue.1 SUPPL. , pp. 24-28
    • Rapeport, W.1    Muirhead, D.2    Williams, S.3    Cross, M.4    Wesnes, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.