Early Phase II Trial of Gd-BOPTA (E7155) for the MR Imaging of Liver Tumors

Nippon Acta Radiologica

Volumn 56, Issue 8, 1996, Pages 555-563

  Kuwatsuru, Ryohei ^a   Kadoya, Masumi ^b   Tanimoto, Akihiro ^c   Hirohashi, Shinji ^d   Katayama, Hitoshi ^a  

^a School of Medicine

^b KANAZAWA UNIVERSITY   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Contrast media; Gd BOPTA; Liver; MRI

Indexed keywords

CONTRAST MEDIUM; DIAGNOSTIC AGENT; DRUG DERIVATIVE; GADOBENIC ACID; MEGLUMINE; ORGANOMETALLIC COMPOUND;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; MIDDLE AGED; MULTICENTER STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; PHASE 2 CLINICAL TRIAL;

ADOLESCENT; ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CONTRAST MEDIA; FEMALE; HUMANS; LIVER NEOPLASMS; MAGNETIC RESONANCE IMAGING; MALE; MEGLUMINE; MIDDLE AGED; ORGANOMETALLIC COMPOUNDS;

EID: 0030187749     PISSN: 00480428     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Vittadini G, Felder E, Tirone P, et al: B-19036, a potential new hepatobiliary contrast agent for MR proton imaging. Invest Radiol 23(suppl. 1): S246-S248, 1988
2. Personal Communucation from K. Takazawa, MD
3. Vogl T, Pegios W, McMahon C, et al: Gadobenate Dimeglumine-a new contrast agent for MR imaging: preliminary evaluation in healthy volunteers. AJR 158: 887-892, 1992
4. Kreft B, Tanimoto A, Stark D, et al: Enhancement of tumor-liver contrast-to noise ratio with gadobenate dimeglumine in MR imaging of rats. JMRI 3: 41-49, 1993
5. Matsui O, Takashima T, Kadoya M, et al: Dynamic computed tomography during arterial portography: the most sensitive examination for small hepatocellular carcinomas. J Comput Assist Tomogr 9: 19-24, 1985
6. Heiken J, Weyman P, Lee J, et al: Detection of focal hepatic masses: prospective evaluation with CT, delayed CT, CT during arterial portography, and MR imaging. Radiology 171: 47-51, 1989
7. Soyer P, Levesque M, Elias D, et al: Detection of liver metastases from colorectal cancer: comparison of intraoperative US and CT during arterial portography. Radiology 183: 541-544, 1992
8. Soyer P, Bluemke D, Hruban R, et al: Primary malignant neoplasms of the liver: detection with helical CT during arterial portography. Radiology 192: 389-392, 1994
9. Mirowitz S, Lee J, Gutierrez E, et al: Dynamic gadolinium-enhanced rapid acquisition spin-echo MR imaging of the liver. Radiology 179: 371-376, 1991
10. Taupitz M, Hamm B, Speidel A, et al: Multisection FLASH: method for breath-hold MR imaging of the entire liver. Radiology 183: 73-79, 1992