Behavioral deficits induced by bingelike exposure to alcohol in neonatal rats: Importance of developmental timing and number of episodes

Developmental Psychobiology

Volumn 29, Issue 5, 1996, Pages 433-452

  Thomas, Jennifer D ^a   Wasserman, Edward A ^a   West, James R ^b   Goodlett, Charles R ^c  

^a E11 SSH   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL;

ALCOHOL INTOXICATION; ANIMAL; ANIMAL BEHAVIOR; APPETITE; ARTICLE; BRAIN STEM; CEREBELLUM; DOSE RESPONSE; DRUG EFFECT; ESCAPE BEHAVIOR; FEMALE; FETAL ALCOHOL SYNDROME; FOREBRAIN; MALE; MAZE TEST; MOTOR PERFORMANCE; NEWBORN; ORGAN SIZE; ORIENTATION; PREGNANCY; PSYCHOLOGICAL ASPECT; RAT; RECALL; SPRAGUE DAWLEY RAT;

ALCOHOLIC INTOXICATION; ANIMALS; ANIMALS, NEWBORN; APPETITIVE BEHAVIOR; BEHAVIOR, ANIMAL; BRAIN STEM; CEREBELLUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCAPE REACTION; ETHANOL; FEMALE; FETAL ALCOHOL SYNDROME; MALE; MAZE LEARNING; MENTAL RECALL; MOTOR SKILLS; ORGAN SIZE; ORIENTATION; PREGNANCY; PROSENCEPHALON; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030185515     PISSN: 00121630     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2302(199607)29:5<433::AID-DEV3>3.0.CO;2-P     Document Type: Article

References (40)

1. Barr, H. M., Streissguth, A. P., Darby, B. L., & Sampson, P. D. (1990). Prenatal exposure to alcohol, caffeine, tobacco, and aspirin: Effects on fine and gross motor performance in 4-year-old children. Developmental Psychology, 26, 339-348.
2. Bonthius, D. J., & West, J. R. (1990). Alcohol-induced neuronal loss in developing rats: Increased brain damage with binge exposure. Alcoholism: Clinical and Experimental Research, 14, 107-118.
3. Bonthius, D. J., & West, J. R. (1991). Permanent neuronal deficits in rats exposed to alcohol during the brain growth spurt. Teratology, 44, 147-163.
4. Brunner, R. L., & Altman, J. (1973). Locomotor deficits in adult rats with moderate to massive retardation of cerebellar development during infancy. Behavioral Biology, 9, 169-188.
5. Clarren, S. K., Astley, S. J., Bowden, D. M., Lai, H., Rudeen, P. K., Shoemaker, W. J., & Bunt-Milam, A. (1990). Neuroanatomic and neurochemical abnormalities in nonhuman primate infants exposed to weekly doses of ethanol during gestation. Alcoholism: Clinical and Experimental Research, 14, 674-683.
6. Conry, J. (1990). Neuropsychological deficits in fetal alcohol syndrome and fetal alcohol effects. Alcoholism: Clinical and Experimental Research, 14, 650-655.
7. Diaz, J., & Samson, H. H. (1980). Impaired brain growth in neonatal rats exposed to alcohol. Science, 208, 751-753.
8. Dobbing, J., & Sands, J. (1979). Comparative aspects of the brain growth spurt. Early Human Development, 3, 79-83.
9. Driscoll, C. D., Streissguth, A. P., & Riley, E. P. (1990). Prenatal alcohol exposure: Comparability of effects in humans and animal models. Neurotoxicology and Teratology, 12, 231-237.
10. Freeman, J. H., Jr., & Stanton, M. E. (1991). Fimbria-fornix transections disrupt the ontogeny of delayed alternation but not position discrimination in the rat. Behavioral Neuroscience, 105, 386-395.
11. Goodlett, C. R., Bonthius, D. J., Wasserman, E. A., & West, J. R. (1992). An animal model of central nervous system dysfunction associated with fetal alcohol exposure: Behavioral and neuroanatomical correlates. In I. Gormezano & E. A. Wasserman (Eds.), Learning and memory: Behavioral and biological processes (pp. 183-208). Englewood, NJ: Erlbaum.
12. Goodlett, C. R., Leo, J. T., O'Callaghan, J. P., Mahoney, J. C., & West, J. R. (1993). Transient cortical astrogliosis induced by alcohol exposure during the neonatal brain growth spurt in rats. Developmental Brain Research, 72(1), 85-97.
13. Goodlett, C. R., Marcussen, B. L.. & West, J. R. (1990). A single day of alcohol exposure during the brain growth spurt induces brain weight restriction and cerebellar Purkinje cell loss. Alcohol, 7, 107-114.
14. Goodlett, C. R., Nichols, J. M., Halloran, R. W., & West, J. R. (1989). Long-term deficits in water maze spatial conditional alternation performance following retrohippocampal lesions in rats. Behavioural Brain Research, 32, 63-67.
15. Goodlett, C. R., & West, J. R. (1992). Fetal alcohol effects: Rat model of alcohol exposure during the brain growth spurt. In I. S. Zagon & T. A. Slotkin (Eds.), Maternal substance abuse and the developing nervous system (pp. 45-75). San Diego: Academic Press.
16. Greene, P. L., Diaz-Granados, J. L., & Amsel, A. (1992). Blood ethanol concentration from early postnatal exposure: Effects on memory-based learning and hippocampal neuroanatomy in infant and adult rats. Behavioral Neuroscience, 106, 51-61.
17. Hamre, K. M., & West, J. R. (1993). The effects of the timing of ethanol exposure during the brain growth spurt on the number of cerebellar Purkinje and granule cell nuclear profiles. Alcoholism: Clinical and Experimental Research, 93, 610-622.
18. Jacobson, S., Rich, J. A., & Tovskt, N. J. (1979). Delayed myelination and lamination in the cerebral cortex of the albino rat as a result of the fetal alcohol syndrome. Alcoholism: Clinical and Experimental Research, 5, 123-133.
19. Lee, S., Imaki, T., Vale, W., & Rivier, C. (1990). Effect of prenatal exposure to ethanol on the activity of the hypothalamic-pituitary-adrenal axis of the offspring: Importance of the time of exposure to ethanol and possible modulating mechanisms. Molecular and Cellular Neuroscience, 1, 168-177.
20. Marcussen, B. L., Goodlett, C. R., Mahoney, J. C., & West, J. R. (1994). Developing rat Purkinje cells are more vulnerable to alcohol-induced depletion during differentiation than during neurogenesis. Alcohol, 11, 147-156.
21. Meyer, L. S., Kotch, L. E., & Riley, E. P. (1990a). Alterations in gait following ethanol exposure during the brain growth spurt in rats. Alcoholism: Clinical and Experimental Research, 14, 23-27.
22. Meyer, L. S., Kotch, L. E., & Riley, E. P. (1990b). Neonatal ethanol exposure: Functional alterations associated with cerebellar growth retardation. Neurotoxicology and Teratology, 12, 15-22.
23. Napper, R. M. A., & West, J. R. (1993). Decrease in total number of Purkinje cells in the cerebellum of the 10-day-old rat following postnatal ethanol exposure. Alcoholism: Clinical and Experimental Research, 17, 485.
24. Olton, D. S. (1983). Memory functions and the hippocampus. In W. Seifert (Ed.), Neurobiology of the hippocampus (pp. 335-373). New York: Academic Press.
25. Phillips, S. C. (1985). Age-dependent susceptibility of rat cerebellar Purkinje cells to ethanol exposure. Drug and Alcohol Dependence, 16, 273-277.
26. Riley, E. P., Barron, S., & Hannigan, J. H. (1986). Response inhibition deficits following prenatal alcohol exposure: A comparison to the effects of hippocampal lesions in rats. In J. R. West (Ed.), Alcohol and brain development (pp. 71-102). New York: Oxford University Press.
27. Riley, E. P., Lochry, E. A., Shapiro, N. R., & Baldwin, J. (1979). Response perseveration in rats exposed to alcohol prenatally. Pharmacology Biochemistry and Behavior, 10, 255-259.
28. Rosett, H. L., Weiner, L., Lee, A., Zuckerman, B., Dooling, E., & Oppenheimer. E. (1983). Patterns of alcohol consumption and fetal development. Obstetrics and Gynecology, 61, 539-546.
29. Rosett, H. L., Weiner, L., Zuckerman, B., McKinlay, S., & Edelin, K. C. (1980). Reduction of alcohol consumption during pregnancy with benefits to the newborn. Alcoholism: Clinical and Experimental Research, 4, 178-184.
30. Savage, D. D., Queen, S. A., Sanchez, C. F., Paxton, L. L., Mahoney, J. C., Goodlett, C. R., & West, J. R. (1992). Prenatal ethanol exposure during the last third of gestation in rat reduces hippocampal NMDA agonist binding-site density in 45-day-old offspring. Alcohol, 9, 37-41.
31. Smith, I. E., Coles, C. D., Lancaster, J., Fernhoff, P. M., & Falek. A. (1986). The effect of volume and duration of prenatal ethanol exposure on neonatal physical and behavioral development. Neurobehauioral Toxicology and Teratology, 8, 375-381.
32. Stephens, C. J. (1985). Alcohol consumption during pregnancy among southern city women. Drug and Alcohol Dependence, 16, 19-29.
33. Streissguth, A. P., Aase, J. M., Clarren, S. K., Randels, S. P., LaDue, R. A., & Smith, D. F. (1991). Fetal alcohol syndrome in adolescents and adults. The Journal of the American Medical Association, 265, 1961-1967.
34. Streissguth, A. P., Herman, C. S., & Smith. D. W. (1978). Intelligence, behavior, and dysmorphogenesis in the fetal alcohol syndrome: A report on 20 patients. The Journal of Pediatrics, 92, 363-367.
35. Streissguth, A. P., Sampson, P. D., & Barr, H. M. (1989). Neurobehavioral dose-response effects of prenatal alcohol exposure in humans from infancy to adulthood. Annals of the New York Academy of Sciences, 562, 145-158.
36. Sulik, K. K. (1984). Critical periods for alcohol teratogenesis in mice, with special reference to the gastrulation stage of embryogenesis. In M. O'Connor, R. Porter, & J. Whelen (Eds.), Mechanisms of alcohol damage in utero (pp. 124-141). London: Pitman Books, Ltd.
37. Sulik, K. K., Johnston. M. C., Daft, P. A., Russell, W. E., & Dehart, D. B. (1986). Fetal alcohol syndrome and DiGeorge anomaly: Critical ethanol exposure periods for craniofacial malformations as illustrated in an animal model. American Journal of Medical Genetics, 2. 97-112.
38. Thomas, J. D., Goodlett, C. R., Wasserman, E. A., & West, J. R. (1991). Motor coordination deficits associated with cerebellar damage in adult rats induced by alcohol exposure during the brain growth spurt. Alcoholism: Clinical and Experimental Research, 15, 336.
39. West, J. R., Goodlett, C. R., Bonthius, D. J., & Pierce, D. R. (1989). Manipulating peak blood alcohol concentrations in neonatal rats: Review of an animal model for alcohol-related developmental effects. Neurotoxicology, 10, 347-366.
40. West, J. R., Hamre, K. M., & Pierce, D. R. (1984). Delay in brain growth induced by alcohol in artificially reared rat pups. Alcohol, 1, 83-95.