A combined cobalt and C-14 2-deoxyglucose approach to antiepileptic drug assessment

International Journal of Neuroscience

Volumn 86, Issue 1-2, 1996, Pages 55-66

  Krenz, N R ^a   Cooper, R M ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

brain metabolism; cobalt; epilepsy; ethosuximide; ketamine; phenytoin

Indexed keywords

EID: 0030184179     PISSN: 00207454     EISSN: None     Source Type: Journal    
DOI: 10.3109/00207459608986698     Document Type: Article

References (32)

1. Blacklot, J. B., Oldfield, E. H., Dichiro, G., Tran, D., Theodore, W., Wright, D. C. & Larson, S. M. (1987). Effect of barbiturate coma on glucose utilization in normal brain versus gliomas. Journal of Neurosurgery. 67, 71-75.
2. Cooper, R. M. & Thurlow, G. A. (1984). 2-Deoxyglucose uptake in the thalamus of awake rats after neocortical ablations. Experimental Neurology, 86, 261-271.
3. Cooper, R. M., Thurlow, G. A & Rooney, B. J. (1984). 2-Deoxyglucose uptake and histologic changes in rat thalamus after neocortical ablations. Experimental Neurology, 83, 134-143.
4. Craig, C. R., Chiu, P. & Colasanti, B. K. (1976) Effects of diphenylhydantion and trimethadione on seizure activity during cobalt experimental epilepsy in the rat Neuropharmacology, 15, 485-489.
5. Craig, C. R. & Colasanti, B. K. (1986). GABA receptors, lipids and gangliosides in cobalt epileptic focus In A. V. Delgado-Escueta, A A. Ward, D. M. Woodbury & R. J. Porter (Eds.), Basic Mechanisms of the Epilepsies (pp. 379-391). New York, N.Y.: Raven Press.
6. Crosby, G., Crane, A. M. & Sokoloff, L. M. (1982). Local changes in cerebral glucose utilization during ketamine anesthesia. Anesthesiology, 56, 437-443.
7. DeVore, G. R., McQueen, J. K. & Woodbury, D. M (1976). Ketamine hydrochloride and its effect on a chronic cobalt epileptic cortical focus. Epilepsia, 17, 111-117.
8. Dow, R. C., Forfar, J. C. & McQueen, J. K. (1973). The effects of some anticonvulsant drugs on cobalt-induced epilepsy. Epilepsia, 14, 203-212.
9. Frey, K. A. & Agranoff, B. W. (1983). Barbiturate-enhanced detection of brain lesions by carbon-14-labeled 2-deoxyglucose autoradiography. Science, 219, 879-881
10. Frieder, B., Karpiak, S. E. & Rapport, M. M. (1982). Effect of antiepileptic drugs and an anticonvulsant on epileptoform activity induced by antibodies to ganglioside. Experimental Neurology, 78, 644-653.
11. Hammer, R. P & Herkenham, M. (1983). Altered metabolic activity in the cerebral cortex of rats exposed to ketamine. Journal of Comparative Neurology, 220, 396-404.
12. Kemp, J. A., Foster, A. C. & Wong, E. H. F. (1987). Non-competitive antagonists of excitatory amino acid receptors. Trends in Neuroscience, 10, 294-298.
13. Leander, J. D., Rathbun, R. C & Zimmerman, D. M. (1988). Anticonvulsant effects of phencyclidine-like drugs: Relation to N-methyl-d-aspartic acid antagonism. Brain Research, 454, 368-372.
14. Leccese, A. P., Marquis, K. L., Mattia, A. & Moreton, J. E (1986) The convulsant and anticonvulsant effects of phencyclidine (PCP) and PCP analogues in the rat. Behavioral, Brain Research, 19, 163-169.
15. Löscher, W. (1993). Basic aspects of epilepsy. Current Opinion in Neurology & Neurosurgery, 6, 223-232.
16. Macdonald, R. L. (1991). Anticonvulsant drugs, ion channels and neurotransmitter receptors. Current Opinion in Neurology & Neurosurgery, 4, 576-581.
17. Macdonald, R. L. & Kelly, K. M. (1994). Mechanisms of action of currently prescribed and newly developed antiepileptic drugs. Epilepsia, 35(Suppl. 4), S41-S50.
18. Macdonald, R L. & McLean, M. J. (1986). Anticonvulsant drugs: Mechanisms of action. In A. V. Delgado-Escueta, A. A. Ward, D. M. Woodbury and R. J. Porter (Eds.), Basic mechanisms of the epilepsies (pp. 713-736). New York, N.Y.: Raven Press.
19. Macdonald, R. L. & Meldrum, B. S. (1989). General principles: Principles of antiepileptic drug action. In R. Levy, R. Mattson, B Meldrum, J. K. Penry & F. E. Dreifuss (Eds.), Antiepileptic drugs (pp. 59-83). New York, N.Y.: Raven Press.
20. Nehls, D. G., Kurmaji, A., Park, C. K. & McCulloch, J. (1988). Differential effects of competitive and non-competitive N-methyl-D-aspartate antagonists on glucose use in the limbic system. Neuroscience Letters, 91, 204-210
21. Olney, J. W., Labruyere, Wang, G., Wozniak, D. F., Price, M T. & Sesma, M. A. (1991). NMDA antagonist neurotoxicity: Mechanism and prevention. Science, 254, 1515-1518.
22. Olson, M. E. & Renchko, P. (1988). Azaperone-ketamine as a neuroleptic sedative and anaesthetic in rats and mice. Laboratory Animal Science, 38, 299-303.
23. Prichard, J. W. & Ransom, B. R. (1989). Phenobarbital: Mechanisms of action. In R. Levy, R Mattson, B. Meldrum, J. K Penry & F. E. Dreifuss (Eds.), Antiepileptic drugs (pp. 267-282). New York, N.Y.: Raven Press.
24. Rall, T W & Schleifer, L. S. (1990). Drugs effective in the therapy of the epilepsies In A. G. Gilman, T. W. Rall, A. S. Nies & P. Taylor (Eds.), The pharmacological basis of therapeutics (pp. 436-462). New York, N.Y.: Macmillan Publishing.
25. Scuvee-Moreau, J., Lepot, M., Brotchi, J , Gerebtzoff, M. A & Dresse, A. (1977). Action of phenytoin, ethosuximide, and of the carbidopa-L-dopa association in semi-chronic cobalt-induced epilepsy in the rat. Archives Internationales de Pharmacodynamie et de Therapie, 230, 93-99.
26. 14C]-deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure, and normal values in the conscious and anaesthetized albino rat. Journal of Neurochemistry, 28, 897-916.
27. Theodore, W. H , Bairamian, D., Newmark, M. E., Fishbein, D., Porter, R. J., DiChiro, G., Deitz, M., Baldwin, P., Margolin, R., Brooks, R. & Jacobs, G. (1989). The effect of antiepileptic drugs on cerebral glucose metabolism. Advances in Epileptology, 17, 139-141.
28. Trottier, S., Truchet, M. & Laroudie, C. (1982). Secondary ion microanalysis in the study of cobalt-induced epilepsy in the rat. Experimental Neurology, 76, 231-245
29. 14C 2-deoxyglucose autoradiographic technique provides a metabolic signature of cobalt-induced focal epileptogenesis. Epilepsia, 35, 939-949.
30. Veliskova, J., Velisek, L. Mareš, P. & Rokyta, R. (1990). Ketamine suppresses both bicuculline- and picrotoxin-induced generalized tonic-clonic seizures during ontogenesis. Pharmacology Biochemistry & Behavior, 37, 667-674.
31. Wilder, B. J. (1972). Projection phenomena and secondary epileptogenesis-mirror foci. In D. P. Purpura, J. K. Penry, D. B. Tower, D. M. Woodbury & R. D. Walter (Eds.), Experimental models of epilepsy (pp. 85-111). New York, N.Y.: Raven Press.
32. Zimmerman, F. T. & Burgemeister, B. B. (1958). A new drug for petit mal epilepsy. Neurology, 8, 769-775.