Stimulation of human lymphocyte proliferation and CD40 antigen expression by phosphorothioate oligonucleotides complementary to hepatitis B virus genome

Journal of Viral Hepatitis

Volumn 3, Issue 4, 1996, Pages 167-172

  Chen, C ^a   Zhou, Y ^b   Yao, Z ^b   Zhang, Y ^b   Feng, Z ^b  

^a The 105th Hospital of PLA   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antisense; B lymphocyte; Hepatitis B; Monocyte; Oligonucleotides; T lymphocyte

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CD40 ANTIGEN; HEPATITIS B ANTIBODY; HEPATITIS B VIRUS X PROTEIN; IMMUNOGLOBULIN G; MESSENGER RNA; TRANSACTIVATOR PROTEIN;

ADULT; ARTICLE; B LYMPHOCYTE; BIOSYNTHESIS; CELL CULTURE; CHRONIC DISEASE; COCULTURE; CYTOTOXICITY; FLOW CYTOMETRY; GENETICS; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; MONOCYTE; PROMOTER REGION; SEQUENCE HOMOLOGY; T LYMPHOCYTE; VIRUS GENOME;

ADULT; ANTIGENS, CD40; B-LYMPHOCYTES; CELLS, CULTURED; CHRONIC DISEASE; COCULTURE TECHNIQUES; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; GENOME, VIRAL; HEPATITIS B; HEPATITIS B ANTIBODIES; HEPATITIS B VIRUS; HUMANS; IMMUNOGLOBULIN G; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; MONOCYTES; OLIGONUCLEOTIDES, ANTISENSE; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; SEQUENCE HOMOLOGY, NUCLEIC ACID; T-LYMPHOCYTES; TRANS-ACTIVATORS;

EID: 0030179013     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2893.1996.tb00091.x     Document Type: Article

References (20)

1. Bowyer SM, Dusheiko GM, Schoub BD, Kew MC. Expression of the hepatitis B virus genome in chronic hepatitis B carriers and patients with hepatocellular carcinoma. Proc Natl Acad Sci USA 1987; 84: 847-850.
2. Brechot C, Pourcel C, Louise A, Rain B, Tiollais P. Presence of integrated hepatitis B virus DNA sequences in cellular DNA of human hepatocellular carcinoma. Nature 1980; 286: 533-535.
3. Porres JC, Carreno V, Ruiz M, Marron JA, Bartelome J. Interferon antibodies in patients with chronic HBV infection treated with recombinant interferon. J Hepatol 1989; 8: 351-357.
4. Stein CA, Cheng YC. Antisense oligonucleotides as therapeutic agents - Is the bullet really magical? Science 1993; 261: 1004-1012.
5. Yao ZQ, Zhou YX, Wang AL, Bai XF, Yang WS. Inhibition of hepatitis B viral gene expression by antisense phosphorothioate oligodeoxynucleotides. J Vir Hep 1995; 2: 85-89.
6. Offensperger WB, Offensperger S, Walter E, Teubner K, Igloi G, Blum HE, Gerok W. In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides. EMBO J 1993; 12: 1257-1262.
7. Mojcik CF, Gourley MF, Klinman DM, Krieg AM, Gmelig-Meyling F, Steinberg AD. Administration of a phosphorothioate oligonucleotide antisense to murine endogenous retroviral MCF env causes immune effects in vivo in a sequence-specific manner. Clin Immunol Immunopathol 1993; 67: 130-136.
8. Marcus-Sekura CJ. Techniques for using antisense oligodeoxyribonucleotides to study gene expression. Anal Biochem 1988; 172: 289-295.
9. Krieg AM, Cause WC, Gourley MF, Steinberg AD. A role for endogenous retroviral sequences in the regulation of lymphocyte activation. J Immunol 1989; 143: 2448-2454.
10. Pisetsky DS, Reich CF. Stimulation of murine lymphocyte proliferation by a phosphorothioate oligonucleotide with antisense activity for herpes simplex virus. Life Sci 1994; 54: 101-107.
11. Graf D, Korthauer U, Mages HW, Senger G, Kroczek RA. Cloning of TRAP, a ligand for CD40 on human T cells. Eur J Immunol 1992; 22: 3191-3194.
12. Valle A, Zuber CE, Defrance T, Djossou O, De Rie M, Banchereau J. Activation of human B lymphocytes through CD40 and interleukin 4. Eur J Immunol 1989; 19: 1463-1467.
13. Messina JP, Gilkeson GS, Pisetsky DS. The influence of DNA structure on the in vitro stimulation of murine lymphocytes by natural and synthetic polynucleotide antigens. Cell Immunol 1993; 147: 148-157.
14. Wysocki LT, Sato VL, 'Panning' for lymphocytes: A method for cell selection. Cell Biol 1978; 75: 2844-2848.
15. Zhang WH, Arii S, Sasaoki T, Adachi Y, Funaki N, Higashitsuji H, Fujita S et al. The role of kupffer cells in the surveillance of tumor growth in the liver. J Surg Res 1993; 55: 140-146.
16. Kulka M, Smith CC, Aurelian L, Fishelevich R, Meade K, Miller P, Ts'o POP. Site specificity of the inhibitory effects of oligos (nucleoside methylphosohonate) complementary to the acceptor splice junction of herpes simplex virus type 1 immediate early mRNA 4. Proc Natl Acad Sci USA 1989; 86: 6868-6874.
17. Krieg AM, Gmelig-Meyling F, Gourley MF, Kisch WJ, Chrisey LA, Steinberg AD. Uptake of oligodeoxyribonucleotides by lymphoid cells is heterogeneous and inducible. Antisense Res Dev 1991; 1: 161-165.
18. Sumimoto SI, Heike T, Kanazashi SI, Shintaku N, Jung EY, Hata D, Katamura K et al. Involvement of LFA-1/intercellular adhesion molecule-1-dependent cell adhesion in CD40-mediated inhibition of human B lymphoma cell death induced by surface IgM crosslinking. J Immunol 1994; 153: 2488-2496.
19. Kato T, Kokuho T, Tamura T, Nariuchi H. Mechanisms of T cell contact-dependent B cell activation. J Immunol 1994; 152: 2130-2138.
20. Parry SL, Hasbold J, Holman M, Klaus GGB. Hyercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40. J Immunol 1994; 152: 2821-2829.