Block by N6-L-phenylisopropyl-adenosine of the electrophysiological and morphological correlates of hippocampal ischaemic injury in the gerbil

British Journal of Pharmacology

Volumn 118, Issue 6, 1996, Pages 1551-1557

  Domenici, M R ^a   De Scotti Carolis, A ^a   Sagratella, S ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Electrophysiology; Gerbil; Hippocampal slices; Ischaemia; L PIA

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; PHENYLISOPROPYLADENOSINE; ADENOSINE; ADENOSINE RECEPTOR; DRUG DERIVATIVE; PHENETHYLAMINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CELL STRUCTURE; CONTROLLED STUDY; DENTATE NUCLEUS; ELECTROPHYSIOLOGY; GERBIL; HIPPOCAMPUS; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NERVE FUNCTION; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADENOSINE; ANIMALS; BRAIN ISCHEMIA; ELECTROPHYSIOLOGY; GERBILLINAE; HIPPOCAMPUS; MALE; PHENETHYLAMINES; PHENYLISOPROPYLADENOSINE; PYRAMIDAL CELLS; RECEPTORS, PURINERGIC P1;

EID: 0030178820     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15573.x     Document Type: Article

References (42)

1. BARRACO, R.A., WALTER, G.A., POLASEK, P.M. & PHILLIS, J.W. (1991). Purine concentrations in the cerebrospinal fluid of anaesthetized rats during and after hypoxia. Neurochem. Int., 18, 243-248.
2. BOISSARD, C.G. & GRIBKOFF, V.K. (1993). The effects of the adenosine reuptake inhibitor soluflazine on synaptic potentials and population hypoxic depolarizations in area CA1 of rat hippocampus in vitro. Neuropharmacology, 32, 149-155.
3. BURKE, L.P. & NADLER, J.V. (1988). Regulation of glutamate and aspartate release from slices of the hippocampal CA1 area: effect of adenosine and baclofen. J. Neurochem., 51, 1541-1551.
4. BUTCHER, S., HAGBERG, H., SANDBERG, M. & HAMBERGER, M. (1987). Extracellular purine catabolite and amino acid levels in the rat striatum during severe hypoglycemia: effects of 2-amino-5-phosphonovalerate. Neurochem. Int., 11, 95-99.
5. CHANG, H., SASAKI, T. & KASSELL, N. (1989). Hippocampal unit activity after transient cerebral ischemia in rats. Stroke. 20, 1051-1055.
6. CHOI, D.W. (1987). Ionic dependence of glutamate excitotoxicity. J. Neurosci., 7, 369-379.
7. CORRADETTI, R., LO CONTE, G., MORONI, F., PASSANI, M.B. & PEPEU, G. (1984). Adenosine decreases aspartate and glutamate release from rat hippocampal slices. Eur. J. Pharmacol., 104, 19-25.
8. DOLPHIN, A.C. (1983). The adenosine agonist 2-chloroadenosine inhibits the induction of long-term potentiation in the perforant path. Neurosci. Lett., 39, 83-87.
9. DOLPHIN, A.C. & ARCHER. E.R. (1983). An adenosine agonist inhibits and a cyclic AMP analogue enhances the release of glutamate but not GABA from slices of rat dentate gyrus. Neurosci. Lett., 43, 49-54.
10. DOMENICI, M.R., LONGO, R., SCOTTI DE CAROLIS, A., FRANK, C. & SAGRATELLA, S. (1993). Protective actions of 21-aminosteroids and MK-801 on hypoxia-induced electrophysiological changes in rat hippocampal slices. Eur. J. Pharmacol., 233, 291-293.
11. DRAGUNOW, M. & FAULL, R.L.M. (1988). Neuroprotective effects of adenosine. Trends Pharmacol. Sci., 9, 193-195.
12. DUNWIDDIE, T.V. (1980). Endogenously released adenosine regulates excitability in the in vitro hippocampus. Epilepsia, 21, 541-548.
13. EVANS, M.C., SWAN, J.H. & MELDRUM, B.S. (1987). An adenosine analogue, 2-chloroadenosine, protects against long term development of ischemic cell loss in the rat hippocampus. Neurosci. Lett., 83, 287-292.
14. FASTBOM, J. & FREDHOLM, B.B. (1986). Inhibition of [H3]glutamate release from rat hippocampal slices by 1-phenylisopropyladenosine. Acta Physiol. Scand., 125, 121-123.
15. FOWLER, J.C. (1989). Adenosine antagonists delay hypoxia-induced depression of neuronal activity in hippocampal brain slice. Brain Res., 490, 378-384.
16. FRANK, C., SAGRATELLA, S., BENEDETTI, M. & SCOTTI DE CAROLIS, A. (1988). Comparative influence of calcium blocker and purinergic drugs on epileptiform bursting in rat hippocampal slices. Brain Res., 441, 393-397.
17. FRANK, C., SCOTTI DE CAROLIS, A. & SAGRATELLA, S. (1994). Influence of adenosinergic drugs on the epileptiform and neurotoxic effects of N-methyl-d-aspartate: comparison with the effects of MK801. Arch. Int. Pharmacodyn., 327, 3-12.
18. GOLDBERG, M.P., MONYER, H., WEISS, J.H. & CHOI, D.W. (1988). Adenosine reduces cortical neuronal injury induced by oxygen or glucose deprivation in vitro. Neurosci. Lett., 89, 323-327.
19. GREENE, R.W. & HAAS, H.L. (1991). The electrophysiology of adenosine in the mammalian central nervous system. Prog. Neurobiol., 36, 329-341.
20. HAGBERG, H., ANDERSSON, P., LACAREWICZ, J., JACBSON, I., BUTCHER, S. & SANDBERG, M. (1987). Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia. J. Neurochem., 49, 227-231.
21. HARTLEY, D.M. & CHOI, D.W. (1989). Delayed rescue of N-methylD-aspartate receptor-mediated neuronal injury in cortical culture. J. Pharmacol. Exp. Ther., 250, 752-758.
22. JORGENSEN, M.B. & DIEMER, N.H. (1982). Selective neuron loss after cerebral ischemia in the rat: possible role of transmitter glutamate. Acta Neurol. Scand., 66, 536-546.
23. KAHN, K. (1972). The natural course of experimental cerebral infarction in the gerbil. Neurology, 22, 510-515.
24. KIRINO, T. (1982). Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res., 239, 57-69.
25. LEE, K.S., SCHUBERT, P. & HEINEMANN, U. (1984). The anticonvulsive action of adenosine: a postsynaptic dendritic action by a possible endogenous anticonvulsant. Brain Res., 321, 160-164.
26. LUPICA, C.R., CASS, W.A., ZAHNISER, N.R. & DUNWIDDIE, T.W. (1990). Effects of the selective adenosine A2 receptor agonist CGS 21680 on in vitro electrophysiology, cAMP formation and dopamine release in rat hippocampus and striatum. J. Pharmacol. Exp. Ther., 252, 1134-1141.
27. MAGER, R., FERRONI, S. & SCHUBERT, P. (1990). Adenosine modulates a voltage-dependent chloride conductance in cultured hippocampal neurones. Brain Res., 532, 58-62.
28. 1 receptor. Br. J. Pharmacol., 110, 470-476.
29. MCILWAIN, H. & POLL, J.D. (1986). Adenosine in cerebral homeostatic role: appraisal through actions of homocysteine, colchicine and dipyridamole. J. Neurobiol., 17, 39-49.
30. MELDRUM, B.S. (1985). Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters. Clin. Sci., 68, 113-122.
31. 3H]-adenosine binding sites in rat and guinea pig brain. Neuropharmacology, 21, 575-580.
32. PHILLIS, J.W., KOSTOPOULUS, G.K. & LIMACHER, J.J. (1974). Depression of corticospinal cells by various purines and pyrimidines. Can. J. Physiol. Pharmacol., 52, 1226-1234.
33. PULSINELLI, W.A., BRIERLEY, J.B. & PLUM, F. (1982). Temporal profile of neuronal damage of transient forebrain ischemia. Ann. Neurol., 11, 491-498.
34. RUDOLPHI, K.A., SCHUBERT, P., PARKINSON, F.E. & FREDHOLM, B.B. (1992). Adenosine and brain ischemia. Cerebrovasc. Brain Metab. Rev., 4, 346-358.
35. SHEARDOWN, M.J., SUZDAK, P.D. & NORDHOLM, L. (1993). AMPA, but not NMDA receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24h. Eur. J. Pharmacol., 236, 347-353.
36. SUTHERLAND, G.R., PEELING, J., LESIUK, H.J., BROWNSTONE, R.M., RYDZY, M., SAUNDERS, J.K. & GEIGER, J.D. (1991). The effects of caffeine on ischemic neuronal injury as determined by magnetic resonance imaging and histopathology. Neuroscience, 42, 171-182.
37. URBAN, L., NEILL, K., CRAIN, B., NADLER, J.V. & SOMJEN, G. (1989). Postischemic synaptic physiology in area CA1 of the gerbil hippocampus studied in vitro. J. Neurosci., 9, 3966-3975.
38. VALENTINO, K., NEWCOMB, R., GADBOIS, T., SINGH, T., BOWERSOX, S., BITNER, S., HOFFMAN, B.B., CIARANELLO, R., MIJANICH, G. & RAMACHANDRAN, J. (1993). A selective N-type calcium channel antagonist protects against neuronal loss after global cerebral ischemia. Proc. Natl. Acad. Sci. U.S.A., 90, 7894-7897.
39. VAN CALKER, D., MULLER, M. & HAMPRECT, B. (1979). Adenosine regulates via two different types of receptors the accumulation of cyclic AMP in cultured brain cells. J. Neurochem., 33, 999-1005.
40. 1 receptor agonist or antagonist in cerebral ischemia, Eur. J. Pharmacol., 256, 161-165.
41. YASSIN, M. & SCHOLFIELD, C.N. (1994). NMDA antagonists increase recovery of evoked potentials from slices of rat olfactory cortex after anoxia. Br. J. Pharmacol., 111, 1221-1227.
42. ZENG, Y.C., DOMENICI, M.R., FRANK, C., SAGRATELLA, S. & SCOTTI DE CAROLIS, A. (1992). Effects of adenosinergic drugs on hypoxia-induced electrophysiological changes in rat hippocampal slices. Life Sci., 51, 1073-1082.