Immunosuppressant FK506 prevents messy fiber sprouting induced by kindling stimulation

Neuroscience Research

Volumn 25, Issue 2, 1996, Pages 191-194

  Moriwaki, Akiyoshi ^a   Lu, Yun Fei ^a   Hayashi, Yasushi ^a,c   Tomizawa, Kazuhito ^a   Tokuda, Masaaki ^b   Itano, Toshifumi ^b   Hatase, Osamu ^b   Matsui, Hideki ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b KAGAWA UNIVERSITY   (Japan)

^c NARUTO UNIVERSITY OF EDUCATION   (Japan)

Author keywords

Calcineurin; FK506; Kindling; Mossy fiber; Phosphatase; Sprouting; Timm histochemistry

Indexed keywords

CALCINEURIN; IMMUNOSUPPRESSIVE AGENT; TACROLIMUS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; GRANULE CELL; HIPPOCAMPUS; INTRAPERITONEAL DRUG ADMINISTRATION; KINDLING; MALE; MOSSY FIBER; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; RAT; STIMULATION; SYNAPTOGENESIS;

EID: 0030176420     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(96)01036-X     Document Type: Article

References (21)

1. Babb, T.L., Kupfer, W.R., Pretorius, J.K., Crandall, P.M. and Levesque, M.F. (1991) Synaptic reorganization by mossy fibers in human epileptic fascia dentata. Neuroscience, 42: 351-363.
2. Benowitz, L.I. and Routtenberg, A. (1987) A membrane phosphoprotein associated with neural development, axonal regeneration, phospholipid metabolism and synaptic plasticity. Trends Neurosci., 10: 527-532.
3. Cavazos, J.E., Golarai, G. and Sutula, T.P. (1991) Mossy fiber synaptic reorganization induced by kindling: Time course of development, progression, and permanence. J. Neurosci., 11: 2795-2803.
4. Chang, H.Y., Takei, K., Sydor, A.M., Born, T., Rusnak, F. and Jay, D.G. (1995) Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin. Nature, 376: 686-690.
5. Clipstone, N.A. and Crabtree, G.R. (1992) Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature, 357: 695-697.
6. Ferreira, A., Kincaid, R. and Kosik, K.S. (1993) Calcineurin is associated with the cytoskeleton of cultured neurons and has a role in the acquisition of polarity. Mol. Biol. Cell, 4: 1225-1238.
7. Kino, T. and Goto, T. (1993) Discovery of FK-506 and update. Ann. NY Acad. Sci., 685: 13-21.
8. Liu, J., Farmer, J.D. Jr., Lane, W.S., Friedman, J., Weissman, I. and Schreiber, S.L. (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell, 66: 807-815.
9. Lyons, W.E., George, E.B., Dawson, T.M., Steiner, J.P. and Snyder, S.H. (1994) Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia. Proc. Natl. Acad. Sci. USA, 91: 3191-3195.
10. Meiri, K.F., Bickerstaff, L.E., and Schwob, J.E. (1991) Monoclonal antibodies show that kinase C phosphorylation of GAP-43 during axonogenesis is both spatially and temporally restricted in vivo. J. Cell Biol., 112: 991-1005.
11. Moia, L.J.M.P., Matsui, H., de Barros, G.A.M., Tomizawa, K., Miyamoto, K., Kuwata, Y., Tokuda, M., Itano, T. and Hatase, O. (1994) Immunosuppressants and calcineurin inhibitors, cyclosporin A and FK506, reversibly inhibit epileptogenesis in amygdaloid kindled rat. Brain Res., 648: 337-341.
12. Paxinos, G. and Watson, C. (1986) The Rat Brain in Stereotaxic Coordinates, Academic Press, New York.
13. Racine, R.J. (1972) Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroencephalogr, Clin, Neurophysiol., 32: 281-294.
14. Represa, A. and Ben-Ari, Y. (1992) Kindling is associated with the formation of novel mossy fiber synapses in the CA3 region. Exp. Brain Res., 92: 69-78.
15. Seiden, S.C. and Pollard, T.D. (1983) Phosphorylation of microtubule-associated proteins regulates their interaction with actin filaments. J. Biol. Chem., 258: 7064-7071.
16. Snipes, G.J., Costello, B., McGuire, C.B., Mayes, B.N., Bock, S.S., Norden, J.J. and Freeman, J.A. (1987) Regulation of specific neuronal and nonneuronal proteins during development and following injury in the rat central nervous system. Prog. Brain Res., 71: 155-175.
17. Snyder, S.H. and Sabatini, D.M. (1995) Immunophilins and the nervous system. Nature Med., 1: 32-37.
18. Sutula, T., Xiao-Xian, H., Cavazos, J. and Scott, G. (1988) Synaptic reorganization in the hippocampus induced by abnormal functional activity. Science, 239: 1147-1150.
19. Tetzlaff, W., Alexander, S.W., Miller, F.D. and Bisby, M.A. (1991) Response of facial and rubrospinal neurons to axotomy: Changes in mRNA expression for cytoskeletal proteins and GAP-43. J. Neurosci., 11: 2528-2544.
20. Uemura, S., Watanabe, Y. and Kimura, H. (1993) Mossy fiber sprouting in amygdala and perforant path kindled rats. Jpn. J. Psychiatr. Neurol., 47: 385-386.
21. Van der Zee, C.E.E.M., Rashid, K., Le, K., Moore, K.A., Stanisz, J., Diamond, J., Racine, J.R. and Fahnestock, M. (1995) Intraventricular administration of antibodies to nerve growth factor retards kindling and blocks mossy fiber sprouting in adult rats. J. Neurosci., 15: 5316-5323.