Dual function of drosophila cells as APCs for naive CD8+ T cells: Implications for tumor immunotherapy

Immunity

Volumn 4, Issue 6, 1996, Pages 555-564

  Sun, Siquan ^a   Cai, Zeling ^a   Langlade Demoyen, Pierre ^a,b   Kosaka, Hiroshi ^a,c   Brunmark, Anders ^a,d   Jackson, Michael R ^a,d   Peterson, Per A ^a,d   Sprent, Jonathan ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b INSTITUT PASTEUR   (France)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

^d R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DROSOPHILA; LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE; TUMOR REJECTION;

EID: 0030176286     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80482-3     Document Type: Article

References (34)

1. Azuma, M., Ito, D., Yagita, H., Okumura, K., Phillips, J.H., Lanier, L.L., and Somoza, C. (1993). B70 antigen is a second ligand for CTLA-4 and CD28. Nature 366, 76-79.
2. Bird, A. (1992). The essentials of DNA methylation. Cell 70, 5-8.
3. Bruce, J., Symington, F.W., McKearn, T.J., and Sprent, J. (1981). A monoclonal antibody discriminating between subsets of T and B cells. J. Immunol. 127, 2496-2501.
4. Cai, Z., and Sprent, J. (1994). Resting and activated T cells display different requirements for CD8 molecules. J. Exp. Med. 179, 2005-2015.
5. Ceredig, R., Lowenthal, J., Nabholz, M., and MacDonald, H.R. (1985). Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells. Nature 314, 98-100.
6. Corr, M., Slanetz, A.E., Boyd, L.F., Jelonek, M.T., Khilko, S., Al-Ramadi, B.K., Sang Kim, Y., Maher, S.E., Bothwell, A.L.M., and Margulies, D.H. (1994). T cell receptor-MHC class I peptide interactions: affinity, kinetics, and specificity. Science 265, 946-949.
7. + T cells by delivery of the B7 costimulatory signal on bystander antigen-presenting cells (trans-costimulation). Eur. J. Immunol. 24, 859-866.
8. Doherty, P.C., Allan, W., Eichelberger, M., and Carding, S.R. (1992). Roles of alpha beta and gamma delta T cell subsets in viral immunity. Annu. Rev. Immunol. 10, 123-152.
9. Freeman, G.J., Gribben, J.G., Boussiotis, V.A., Ng, J.W., Restivo, V.A., Jr., Lombard, L.A., Gray, G.S., and Nadler, L.M. (1993). Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation. Science 262, 909-911.
10. Germain, R.N. (1993). Antigen processing and presentation. In Fundamental Immunology, Third Edition, W.E. Paul, ed. (New York: Raven Press), pp. 629-676.
11. Jackson, M.R., Song, E.S., Yang, Y., and Peterson, P.A. (1992). Empty and peptide-containing conformers of class I major histocompatibility complex molecules expressed in Drosophila melanogaster cells. Proc. Natl. Acad. Sci. USA 89, 12117-12121.
12. Janeway, C.A. (1992). The T cell receptor as a multi-component signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation. Annu. Rev. Immunol. 10, 645-674.
13. Janeway, C.A., and Bottomly, K. (1994). Signals and signs for lymphocyte responses. Cell 76, 275-285.
14. Kranz, D.M., Sherman, D.H., Sitkovsky, M.V., Pasternack, M.S., and Eisen, H.N. (1984). Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera. Proc. Natl. Acad. Sci. USA 81, 573-577.
15. Krieg, A.M., Yi, A.K., Matson, S., Waldschmidt, T.J., Bishop, G.A., Teasdale, R., Koretzky, G.A., and Klinman, D.M. (1995). CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374, 546-549.
16. Lane, P., Gerhard, W., Hubele, S., Lanzavecchia, A., and McConnell, F. (1993). Expression and functional properties of mouse B7/BB1 using a fusion protein between mouse CTLA4 and human gamma 1. Immunology 80, 56-61.
17. Liu, Y., and Janeway, C.A., Jr. (1992). Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells. Proc. Natl. Acad. Sci. USA 89, 3845-3849.
18. Mueller, D.L., Jenkins, M.K., and Schwartz, R.H. (1989). Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy. Annu. Rev. Immunol. 7, 445-480.
19. b haplotype reveal genetic control of isotype expression. J. Immunol. 126, 317-321.
20. Pisetsky, D.S. (1996). The immunologic properties of DNA. J. Immunol. 156, 421-423.
21. Reddehase, M.J., Rothbard, J.B., and Koszinowski, U.H. (1989). A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes. Nature 337, 651-653.
22. Sarmiento, M., Glasebrook, A.L., and Fitch, F.W. (1980). IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt 2 antigen block T cell-mediated cytolysis in the absence of complement. J. Immunol. 125, 2665-2672.
23. Schwartz, R.H. (1992). Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell 71, 1065-1068.
24. Sha, W.C., Nelson, C.A., Newberry, R.D., Kranz, D.M., Russell, J.H., and Loh, D.Y. (1988). Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice. Nature 335, 271-274.
25. b mutations that involve peptide binding. Proc. Natl. Acad. Sci. USA 87, 6186-6190.
26. Sprent, J., and Schaefer, M. (1985). Properties of purified T cell subsets. I. In vitro responses to class I vs. class II H-2 alloantigens. J. Exp. Med. 162, 2068-2088.
27. Strauss, W.M. (1990). Preparation of genomic DNA from mammalian tissue. Curr. Prot. Mol. Biol. 1, 2.2.1-2.2.3.
28. Sykulev, Y., Brunmark, A., Jackson, M., Cohen, R.J., Peterson, P.A., and Eisen, H.N. (1994a). Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes. Immunity 1, 15-22.
29. Sykulev, Y., Brunmark, A., Tsomides, T.J., Kageyama, S., Jackson, M., Peterson, P.A., and Eisen, H.N. (1994b). High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. Proc. Natl. Acad. Sci. USA 91, 11487-11491.
30. Tough, D.F., and Sprent, J. (1994). Turnover of naive-and memory-phenotype T cells. J. Exp. Med. 179, 1127-1135.
31. + cytotoxic T lymphocytes in association with a class I MHC protein. Cell 69, 989-998.
32. Uyttenhove, C., Maryanski, J., and Boon, T. (1983). Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression. J. Exp. Med. 157, 1040-1052.
33. van den Eynde, B., Lethe, B., van Pel, A., De Plaen, E., and Boon, T. (1991). The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice. J. Exp. Med. 173, 1373-1384.
34. Whitton, J.L., Tishon, A., Lewicki, H., Gebhard, J., Cook, T., Salvato, M., Joly, E., and Oldstone, M.B.A. (1989). Molecular analyses of a five-amino-acid cytotoxic T-lymphocyte (CTL) epitope: an immuno-dominant region which induces nonreciprocal CTL cross-reactivity. J. Virol. 63, 4303-4310.