Acute electrical stimulation of lateral hypothaslamus increases natural killer cell activity in rats

Journal of Neuroimmunology

Volumn 67, Issue 1, 1996, Pages 67-70

  Wenner, Marcus ^a,b   Kawamura, Noriyuki ^a,b   Miyazawa, Hitoshi ^a   Ago, Yukihiro ^b   Ishikawa, Toshio ^b   Yamamoto, Hiroshi ^a  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

Author keywords

Electrical stimulation; Lateral hypothalamus; Natural killer cells; Rat; Reward; Stress

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; ELECTRICITY; FRONTAL CORTEX; LATERAL HYPOTHALAMUS; MALE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; STRESS;

EID: 0030176197     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(96)00040-9     Document Type: Article

References (21)

1. Bartrop, W., Luckhurst, E., Lazarus, L., Kiloh, L.G. and Penny, R. (1977) Depressed lymphocyte function after bereavement. Lancet i, 834-836.
2. Blalock, J.E. (1991) The syntax of immune-neuroendocrine communication. Immunol. Today. 15(11), 504-511.
3. Cross, R.J., Markesbery, W.H., Brooks, W.H. and Roszman, T.L. (1984) Hypothalamic-immune interactions: neuromodulation of natural killer activity by lesioning of the anterior hypothalamus. Immunology, 51, 399-405.
4. Evans, D.L., Leserman, J., Perkins, D.O., Stern, R.A., Murphy, C., Tamul, K., Liao, D.P., Vanderhorst, C.M., Hall, C.D., Folds, J.D., Golden, R.N. and Petitto, J.M. (1995) Stress associated reductions of cytotoxic t-lymphocytes and natural killer cells in asymptomatic hiv-infection. Am. J. Psychiatry 152, 543-550.
5. Fawzy, I., Kemeny, M.E., Fawzy, N.W., Elaschof, R., Morton, D., Cousins, N. and Fahey, J.L. (1990) A structured psychiatric intervention for cancer patients. II. Changes over time in immunological measures. Arch. Gen. Psychiatry 47, 726-730.
6. Greer, S., Morris, T., Pettingale, K.W. and Haybitte, J.L. (1990) Psychological response to breast cancer and 15 year outcome. Lancet i, 49-50.
7. Greer, S. (1991) Psychologica response to cancer and survival. Psychol. Med. 21, 43-49.
8. Holmes, T.H. and Masuda, M. (1974) Life changes and illness. In: ed. B.S. Dohrenwend and B.P. Dohrenwend, Stressful Life Events: Their Nature and Effects. Wiley, New York.
9. Jones, K. and Vischi, T. (1980) Impact of alcohol, drug abuse and mental health treatment of medical health care utilization: a review of the literature. Med. I Care 17 (Suppl. 2), 1-82.
10. Katafuchi, T., Take, S. and Hori, T. (1993) Roles of sympathetic nervous system in the suppression of cytotoxicity of splenic natural killer cells in the rat. J. Physiol. 465, 343-357.
11. Kiecolt-Glaser, J.K., Glaser, R., Williger, D., Stout, J., Messik, G., Sheppard, S., Ricker, D., Romisher, S.C., Briner, W., Bonnell, G. and Donnerberg, R. (1985) Psychosocial enhancement of immunocompetence in a geriatric population. Health Psychol. 4, 25-41.
12. Kiecolt-Glaser, J.K., Kennedy, S., Malkoff, S., Fischer, L., Speicher, C.E. and Glaser, R. (1988) Marital discord and immunity in males. Psychosom. Med. 50, 213-229.
13. McCutcheon, N.B., Guile, M.N. and McCormick, R. (1986) Electrical stimulation of medial forebrain bundle-posterior lateral hypothalamus attenuates gastric lesions. Physiol. Behav. 37, 4335-4340.
14. Milner, P. (1989) Discovery of self stimulation and other stories. Neurosci. Biobehav. Rev. 13, 61-67.
15. Mumford, E., Schlesinger, H.J. and Glass, G.V. (1981) Reducing medical costs through mental health treatment: research problems and recommendations. In: ed. A. Broskowski, E. Marks and S.H. Budman, Linking Health and Mental Health. Sage, Beverly Hills, CA, pp. 257-273.
16. Okamoto, S., Terao, A., Morimatsu, M. and Saito, M. (1994) Sympathetic nerve mediated suppression of splenic lymphocyte functions by ventromedial hypothalamic stimulation. Neurosci. Res. Suppl. 19, s111.
17. Paxinos, G. and Watson, C. (1982) The Rat Brain in Stereotaxic Coordinates. Academic Press, San Diego.
18. Sakic, B. and Vlajkovic, S. (1990) Self stimulation behaviour: consequences upon immunity? Brain Behav. 4, 255-264.
19. Selye, H. (1954) An experimental model illustrating the pathogenesis of the deseases of adaptation. J. C. E. M. 14, 997-1005.
20. Talan, M.I., Engel, B.T. and Whitaker, J.R. (1984) Age related decline in cold tolerance can be retarded by brain stimulation. Physiol. Behav. 33, 969-973.
21. Wrona, D., Jurkowski, M.K., Trojniar, W., Staszewska, M. and Tokarski, J. ( 1994) Electrolytic lesions of the lateral hypothalamus influence peripheral blood NK cytotoxicity in rats. J. Neuroimmunol. 55, 45-54.