Biosynthesis of endothelium-derived nitric oxide by bradykinin as endogenous precursor

Immunopharmacology

Volumn 33, Issue 1-3, 1996, Pages 287-290

  Volpe, Anna Rita ^a   Giardina, Bruno ^a   Preziosi, Paolo ^a   Carmignani, Marco ^b  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

bradykinin; Langendorff model; nitric oxide

Indexed keywords

1,10 PHENANTHROLINE; ARGININE; BRADYKININ; BRADYKININ[1-8]; ICATIBANT; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ANIMAL TISSUE; BIOSYNTHESIS; CONFERENCE PAPER; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DRUG MECHANISM; HEART FUNCTION; HEART MUSCLE CONTRACTILITY; HEART PERFUSION; HEART RATE; MALE; NONHUMAN; PRECURSOR; PRIORITY JOURNAL; RAT;

EID: 0030175883     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/0162-3109(96)00043-4     Document Type: Conference Paper

References (10)

1. Carmignani M, Volpe AR, Porcelli G, Preziosi P. Nitric oxide and interactions among enkephalinergic, renin-angiotensin and kallikrein-kinin systems in the heart. Pharmacol Res 1992; 26: 229.
2. Cherry PD, Furchgott RF, Zawadzki JV, Jothianandan D. Role of endothelial cells in relaxation of isolated arteries by bradykinin. Proc Natl Acad Sci USA 1982; 72: 2106-2110.
3. Gryglewski RJ, Moncada S, Palmer RMJ. Bioassay of prostacyclin and endothelium-derived relaxing factor (EDRF) from porcine aortic endothelial cells. Br J Pharmacol 1986; 87: 685-694.
4. Ignarro LJ, Byrns RE, Buga GM, Wood KS. Mechanisms of endothelium-dependent vascular smooth muscle relaxation elicited by bradykinin and VIP. Am J Physiol 1987; 253: H1074-H1082.
5. Ignarro LJ, Gold ME, Buga GM, Byrns RE, Woods KS. Basic polyaminoacids rich in arginine, lysine or ornithine cause both enhancement of and refractoriness to formation of endothelium-derived nitric oxide in pulmonary artery and vein. Circulation Res 1989; 64: 315-329.
6. Ignarro LJ. Biosynthesis and metabolism of endothelium-derived nitric oxide. Ann Rev Pharmacol Toxicol 1990; 30:535-560.
7. Regoli D, Barabé J. Pharmacology of bradykinin and related kinins. Pharmacol Rev 1980; 32: 1-46.
8. Stewart JM, Vavrek RJ. Bradykinin competitive antagonists for classical kinin systems. Adv Exp Med Biol 1986; 198A: 537-542.
9. Vanhoutte PM, Auchschwelk W, Biondi ML, Lorenz RR, Schini VB, Vidal MJ. Why are converting enzyme inhibitors vasodilatators? Br J Clin Pharmacol 1989; 28: 95-104.
10. Vegh A, Papp JG, Szerekes L., Parratt JR. Prevention by an inhibitor of L-arginine-nitric oxide pathways of the anti-arrhythmic effect of bradykinin in anaesthetized dog. Br J Pharmacol 1993; 110: 18-19.