Potential doubling time and clinical outcome in head and neck squamous cell carcinoma treated with 70 Gy in 7 weeks

International Journal of Radiation Oncology Biology Physics

Volumn 35, Issue 3, 1996, Pages 471-476

  Bourhis, Jean ^a   Dendale, Rémi ^a   Hill, Catherine ^a   Bosq, Jacques ^a   Janot, François ^a   Attal, Pierre ^b   Fortin, André ^a   Marandas, Patrick ^a   Schwaab, Guy ^a   Wibault, Pierre ^a   Malaise, Edmond Phillippe ^a   Bobin, Serge ^b   Luboinski, Bernard ^a   Eschwege, François ^a   Wilson, George ^c  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b BICÊTRE HOSPITAL   (France)

^c MOUNT VERNON HOSPITAL   (United Kingdom)

Author keywords

Doubling time; Head and neck squamous cell carcinoma; T(pot)

Indexed keywords

BROXURIDINE;

ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CELL CYCLE S PHASE; CLINICAL TRIAL; FEMALE; HEAD AND NECK CARCINOMA; HUMAN; LABELING INDEX; MAJOR CLINICAL STUDY; MALE; OROPHARYNX CARCINOMA; PRIORITY JOURNAL; PROSPECTIVE STUDY; SQUAMOUS CELL CARCINOMA; TREATMENT OUTCOME;

EID: 0030175490     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(96)80008-3     Document Type: Article

References (31)

1. 1. Amdur, R.; Parson, J.; Mendenhall, W.; Million, R.; Cassini, N. Split-course vs. continuous-course irradiation in the postoperative setting for squamous cell carcinoma of the head and neck. Int. J. Radiat. Oncol. Biol. Phys. 17:279-285; 1989.
2. 2. Barton, M.; Keane, T.; Gadalla, T.; Maki, E. The effect of treatment time and treatment interruption on tumour control following radical radiotherapy of oropharyngeal cancer. Radiother. Oncol. 23:137-143; 1992.
3. 3. Begg, A. C.; Hofland, L.; Moonen, H. The predictive value of cell kinetic measurement in a European trial of accelerated fractionation in advanced head and neck tumors: An interim report. Int. J. Radiat. Oncol. Biol. Phys. 19:1449-1453; 1990.
4. 4. Begg, A. C.; McNally, N. J. A method to measure the duration of DNA synthesis and the potential doubling time from a single sample. Cytometry 6:620-623; 1985.
5. 5. Begg, A. C.; Moonen, L.; Hofland, I.; Dessing, M.; Barteling, H. Human tumour cell kinetics using a monoclonal antibody against iododeoxyuridine: Intra-tumoral sampling variations. Radiother. Oncol. 11:337-347; 1988.
6. 6. Bennet, M.; Wilson, G.; Dische, S.; Saunders, M.; Martindale, C.; O'Halloran, A. Tumour proliferation assessed by combined histological and flow cytometric analysis: Implications for therapy in squamous cell carcinoma in the head and neck. Br. J. Cancer 65:870-878; 1992.
7. 7. Bourhis, J.; Fortin, A.; Dupuis, O.; Lusinchi, A.; Mamelle, G.; Schwaab, G.; Armand, J. P.; Luboinski, B.; Malaise, E. P.; Eschwege, F.; Wilbaut, P. Very accelerated radiotherapy in locally unresectable head and neck squamous cell carcinoma. Int. J. Radiat. Oncol. Biol. Phys. 32:747-752; 1995.
8. 8. Bourhis, J.; Wilson, G.; Bosq, J.; Janot, F.; Wibault, P.; Luboinski, B.; Eschwege, F.; Malaise, E. P. Rapid tumor cell proliferation after induction chemotherapy in oropharyngeal cancer. Laryngoscope 104:468-472; 1994.
9. 9. Bourhis, J.; Wilson, G.; Wibault, P.; Janot, F.; Bosq, J.; Chavaudra, N.; Luboinski, B.; Eschwege, F.; Malaise, E. P. In vivo measurement of the potential doubling time by flow-cytometry in oropharyngeal cancer treated by conventional radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 26:793-799; 1993.
10. 10. Cooke, L.; Cooke, T.; Forster, G.; Jones, A.; Stell, P. Prospective evaluation of cell kinetics in head and neck squamous cell carcinoma: The relationship to tumour factors and survival. Br. J. Cancer 69:717-720; 1994.
11. 11. Corvo, R.; Giaretti, W.; Sanguineti, G.; Geido, E.; Orecchia, R.; Bara, S.; Margarino, G.; Bacigalupo, A.; Vitale, V. In vivo cell kinetics in head and neck squamous cell carcinomas predicts local control and helps guide radiotherapy regimen. J. Clin. Oncol 13:1843-1850; 1995.
12. 12. Dische, S.; Saunders, M. The rationale for continuous hyperfractionated accelerated radiotherapy (CHART). Int. J. Radiat. Oncol. Biol. Phys. 19:1317-1320; 1990.
13. 13. Dixon, W. J. BMDP statistical software. Berkeley: CA University of California Press; 1981.
14. 14. Fowler, J. F. How worthwhile are short schedules in radiotherapy? A series of exploratory calculations. Radiother. Oncol. 18:165-181; 1990.
15. 15. Fowler, J. F. Rapid repopulation in radiotherapy: Debate on mechanism. The phantom of tumor treatment - Continually rapid repopulation unmasked. Radiother. Oncol. 22:156-158; 1991.
16. 16. Horiot, J. C.; LeFur, P.; N'Guyen, T.; et al. Hyperfractionated compared with conventional radiotherapy in oropharyngeal carcinoma: an EORTC randomized trial. Eur. J. Cancer 26:779-780; 1990.
17. 17. Lochrin, C.; Wilson, G. D.; McNally, N. Tumors cell kinetics, local tumor control and accelerated radiotherapy. A preliminary report. Int. J. Radiat. Oncol. Biol. Phys. 24:87-91; 1992.
18. 18. Mendenhall, W.; Parson, J.; Milion, R.; Fletcher, G. T1-T2 squamous cell carcinoma of the glottic larynx treated with radiation therapy: Relationship of dose-fractionation factors to local control and complications. Int. J. Radiat. Oncol. Biol. Phys. 15:1267-1273; 1988.
19. 19. Nilander, K.; Anneroth, G.; Gustafsson, H.; Roos, G.; Stentling, R.; Zackrinson, B. Cell kinetics of head and neck squamous cell carcinomas. Acta Oncol. 27:147-161; 1988.
20. 20. Overgaard, J.; Hjelm-Hansen, M.; Vendelbo, J. Comparison of conventional and split-course as primary treatment in carcinoma of the larynx. Acta Oncol. 27:147-161; 1988.
21. 21. Ritter, M.; Kinsella, T.; Kim, Y.; Gilchrist, K.; Fowler, J. Modifications of the delayed biopsy technique for human proliferation kinetics. Int. J. Radiat. Oncol. Biol. Phys. 21:133; 1991.
22. 22. Speke, A. K.; Hill, R. P. Repopulation kinetics during fractionated irradiation and the relationship to the potential doubling time. Int. J. Radiat. Oncol. Biol. Phys. 31:819-826; 1995.
23. 23. Taylor, J.; Withers, H.; Mendenhall, W. Dose-time consideration of head and neck squamous cell carcinomas treated with irradiation. Radiother. Oncol. 17:95-102; 1990.
24. 24. Thames, H. D.; Peters, L.; Withers, H.; Fletcher, G. Accelerated fractionation vs. hyperfractionation: Rationales for several treatments per day. Int. J. Radiat. Oncol. Biol. Phys. 9:127-132; 1983.
25. 25. Thomas, F.; Ozanne, F.; Mamelle, G.; Wibault, P.; Eschwege, F. Radiotherapy alone for oropharyngal carcinoma: The role of fraction stage (2 Gy vs. 2.5 Gy) on local control and early and late complications. Int. J. Radiat. Oncol. Biol. Phys. 15:1097-1102; 1988.
26. 26. Trott, K.; Kummermehr, J. Rapid repopulation in radiotherapy: Debate on mechanism, accelerated repopulation in tumor and normal tissue. Radiother. Oncol. 22:159-160; 1991.
27. 27. Trott, K. R.; Kummermehr, J. What is known about tumour proliferation rates to choose between acccelerated fractionation or hyperfractionation? Radiother. Oncol. 3:1; 1985.
28. 28. Valente, G.; Orecchia, R.; Gandolfo, S.; Arnaudo, M.; Ragona, R.; Kerim, S.; Palestro, G. Can Ki67 immunostaining predict response to radiotherapy in oral squamous cell carcinoma? Clin. Pathol. 47:109-112; 1994.
29. 29. Wilson, G.; McNally, N. In: Hall, P.; Levison, D., eds. Assessment of cell proliferation in clinical practice. Berlin: Springer Verlag; 1989.
30. 30. Wilson, G. D.; McNally, N. J.; Dische, S.; Bennet, M. Cell proliferation in human tumours measured by in vivo labelling with bromodeoxyuridine. Br. J. Cancer 58:423-431; 1988.
31. 31. Withers, H.; Taylor, J.; Maciejevski, B. The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncol. 27:131-146; 1988.