IGF-I resistance in virus-transformed B-lymphocytes from African Efe Pygmies

Biochemical and Molecular Medicine

Volumn 58, Issue 1, 1996, Pages 31-36

  Cortez, Alan B ^a   Van Dop, Cornelis ^a   Bailey, Robert C ^a   Bersch, Noelle ^a   Scott, Marilyn ^a   Golde, David W ^b   Geffner, Mitchell E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; PHORBOL MYRISTATE; SOMATOMEDIN B; SOMATOMEDIN C;

ARTICLE; B LYMPHOCYTE; CELL PROLIFERATION; DOSE RESPONSE; EPSTEIN BARR VIRUS; FEMALE; HORMONE RESISTANCE; HUMAN; HUMAN EXPERIMENT; MALE; MOLECULAR CLONING; SHORT STATURE; VIRUS TRANSFORMATION;

EID: 0030175488     PISSN: 10773150     EISSN: None     Source Type: Journal    
DOI: 10.1006/bmme.1996.0029     Document Type: Article

References (11)

1. 1. Diamond JM. Why are Pygmies small? Nature 354:111-112, 1991.
2. 2. Bailey RC. The comparative growth of Efe Pygmies and African farmers from birth to age 5 years. Ann Hum Biol 18:113-120, 1991.
3. 3. Merrimee TJ, Rimoin DL, Rabinowitz D, Cavilli-Sforza LL, McKusick VA. Metabolic studies in the African pygmy: Trans Assoc Am Phys 81:221-230, 1968.
4. 4. Merrimee TJ. Growth hormone and IGF abnormalities of the African pygmy. In Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors (LeRoith D, Raizada MK, Eds.) New York: Plenum, 1989, pp 73-80.
5. 5. Geffner ME, Bailey RC, Bersch N, Vera J, Golde DW. Insulin-like growth factor-I unresponsiveness in an Efe Pygmy. Biochem Biophys Res Commun 193:1216-1223, 1993.
6. 6. Geffner ME, Bersch N, Bailey RC, Golde DW. Insulin-like growth factor-I resistance in immortalized T-cell lines from African Efe Pygmies. J Clin Endocrinol Metab 80:3732-3738, 1995.
7. 7. Tosato G. Generation of Epstein-Barr virus (EBV)-immortalized B-cell lines. In Current Protocols in Immunology, New York: Greene Publishing Associates/Wiley - Interscience, 1991, pp 7.22.1-7.22.3.
8. 8. Geffner ME, Bersch N, Golde DW. Insulin and IGF-I stimulate normal and virally transformed T-lymphocyte cell growth in vitro. Brain Behav Immunol 6:377-386, 1992.
9. 9. DeVivo M, Iyengar R. G protein pathways: signal processing by effectors. Mol Cell Endocrinol 100:65-70, 1994.
10. 10. Geffner ME, Bersch N, Cortez AB, Bailey RC, Golde DW. Growth-promoting actions of parathyroid hormone, adrenocorticotrophic hormone, and thyroid-stimulating hormone: in vitro studies in normal and Pygmy T-lymphoblast cell lines. Pediatr Res 37:507-511, 1995.
11. 11. Cortez AB, Van Dop C, Geffner ME. Parathyroid hormone (PTH) stimulates clonal proliferation of B-lymphocytes transformed by Epstein-Barr virus (EBV). Pediatr Res 35:97A, 1994.