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1
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0028931102
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CpG motifs in bacterial DNA trigger direct B-cell activation
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of special interest. Describes that bacterial DNA can trigger B-cell proliferation.
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Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, Koretzky GA, Klinman DM. CpG motifs in bacterial DNA trigger direct B-cell activation. of special interest Nature. 374:1995;546-549 Describes that bacterial DNA can trigger B-cell proliferation.
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Nature
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Krieg, A.M.1
Yi, A.K.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretzky, G.A.7
Klinman, D.M.8
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2
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0029091255
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Successful T cell priming in B cell-deficient mice
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Epstein MM, Di Rosa F, Jankovic D, Sher A, Matzinger P. Successful T cell priming in B cell-deficient mice. J Exp Med. 182:1995;915-922.
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Epstein, M.M.1
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Jankovic, D.3
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3
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0028979466
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New perspectives of CD28-B7 mediated T cell costimulation
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Bluestone JA. New perspectives of CD28-B7 mediated T cell costimulation. Immunity. 2:1995;559-564.
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Immunity
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Bluestone, J.A.1
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4
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0029043647
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A novel receptor involved in T-cell activation
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Cocks BG, Chang CC, Carballido JM, Yssel H, De Vries JE, Aversa G. A novel receptor involved in T-cell activation. Nature. 376:1995;260-263.
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Cocks, B.G.1
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Yssel, H.4
De Vries, J.E.5
Aversa, G.6
-
5
-
-
0028791059
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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4
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of outstanding interest. Describes that CTLA-4 delivers a negative signal to T cells.
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Waterhouse P, Penninger J, Timms E, Wakeham A, Shahinian A, Lee KP, Thompson CB, Griesser H, Mak TW. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. of outstanding interest Science. 270:1995;985-988 Describes that CTLA-4 delivers a negative signal to T cells.
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Waterhouse, P.1
Penninger, J.2
Timms, E.3
Wakeham, A.4
Shahinian, A.5
Lee, K.P.6
Thompson, C.B.7
Griesser, H.8
Mak, T.W.9
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6
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
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of outstanding interest. See annotation [5].
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Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH. Loss of CTLA-4 leads to massive lymphoproliferation and multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. of outstanding interest Immunity. 3:1995;541-547 See annotation [5].
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Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
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7
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0028055141
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Normal T cell priming to a protein antigen in mice transgenic for soluble CTLA-4
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Ronchese F, Hausmann B, Hubele S, Lane P. Normal T cell priming to a protein antigen in mice transgenic for soluble CTLA-4. J Exp Med. 179:1994;809-817.
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Ronchese, F.1
Hausmann, B.2
Hubele, S.3
Lane, P.4
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8
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0029031817
-
In the absence of a CD40 signal B cells are tolerogenic
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of special interest. B cells induce tolerance if CD40 - CD40 ligand interactions are blocked.
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Buhlmann JE, Foy RM, Aruffo A, Crassl KM, Ledbetter JA, Green WR, Xu JC, Shultz LD, Fast L, Noelle RJ, Durie FH. In the absence of a CD40 signal B cells are tolerogenic. of special interest Immunity. 2:1995;645-653 B cells induce tolerance if CD40 - CD40 ligand interactions are blocked.
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Buhlmann, J.E.1
Foy, R.M.2
Aruffo, A.3
Crassl, K.M.4
Ledbetter, J.A.5
Green, W.R.6
Xu, J.C.7
Shultz, L.D.8
Fast, L.9
Noelle, R.J.10
Durie, F.H.11
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9
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0028806723
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Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand
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of special interest. Mice deficient in CD40L prime T cells poorly.
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Grewal IS, Xu J, Flavell RA. Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand. of special interest Nature. 378:1995;617-619 Mice deficient in CD40L prime T cells poorly.
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Nature
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Grewal, I.S.1
Xu, J.2
Flavell, R.A.3
-
10
-
-
0028790434
-
CD40 ligand-transduced costimulation of T cells in the development of helper function
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of special interest. Describes that T cells are primed in CD40-deficient mice, but that they do not help B cells.
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Van Essen D, Kikutani H, Gray G. CD40 ligand-transduced costimulation of T cells in the development of helper function. of special interest Nature. 378:1995;620-623 Describes that T cells are primed in CD40-deficient mice, but that they do not help B cells.
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Nature
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, pp. 620-623
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Van Essen, D.1
Kikutani, H.2
Gray, G.3
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11
-
-
0029862687
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B cells solicit their own help from T cells
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of special interest. Shows that B cells induce T cells to help them.
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Stockinger B, Zal T, Zal A, Gray D. B cells solicit their own help from T cells. of special interest J Exp Med. 183:1995;891-899 Shows that B cells induce T cells to help them.
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Stockinger, B.1
Zal, T.2
Zal, A.3
Gray, D.4
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12
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0023930695
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The role of antigen-presenting B cells in T cell priming in vivo. Studies of B cell-deficient mice
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Kurt-Jones EA, Liano D, HayGlass KA, Benacerraf B, Sy MS, Abbas AK. The role of antigen-presenting B cells in T cell priming in vivo. Studies of B cell-deficient mice. J Immunol. 140:1988;3773-3778.
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Kurt-Jones, E.A.1
Liano, D.2
HayGlass, K.A.3
Benacerraf, B.4
Sy, M.S.5
Abbas, A.K.6
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13
-
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0028329026
-
CD70 represents the human ligand for CD27
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Hintzen RQ, Lens SM, Koopman G, Pale ST, Spits H, Van Lier RA. CD70 represents the human ligand for CD27. Int Immunol. 6:1994;477-480.
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Hintzen, R.Q.1
Lens, S.M.2
Koopman, G.3
Pale, S.T.4
Spits, H.5
Van Lier, R.A.6
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14
-
-
0029045255
-
Crosslinking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells
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Stuber E, Neurath M, Calderhead D, Fell HP, Strober W. Crosslinking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity. 2:1995;507-521.
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Stuber, E.1
Neurath, M.2
Calderhead, D.3
Fell, H.P.4
Strober, W.5
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15
-
-
0028949152
-
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy
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of special interest. Describes the differential effects of B7.1 and B7.2 on T-cell priming.
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Kuchroo VK, Das MP, Brown JA, Ranger AM, Zamvil SS, Sobel RA, Weiner HL, Nabavi N, Glimcher LH. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. of special interest Cell. 80:1995;707-718 Describes the differential effects of B7.1 and B7.2 on T-cell priming.
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Cell.
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Kuchroo, V.K.1
Das, M.P.2
Brown, J.A.3
Ranger, A.M.4
Zamvil, S.S.5
Sobel, R.A.6
Weiner, H.L.7
Nabavi, N.8
Glimcher, L.H.9
-
16
-
-
0029073050
-
B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4
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of special interest. See annotation [15].
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Freeman GJ, Boussiotis VA, Anumanthan A, Bernstein GM, Ke XY, Rennert PD, Gray GS, Gribben JG, Nadler LM. B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4. of special interest Immunity. 2:1995;523-532 See annotation [15].
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Immunity
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Freeman, G.J.1
Boussiotis, V.A.2
Anumanthan, A.3
Bernstein, G.M.4
Ke, X.Y.5
Rennert, P.D.6
Gray, G.S.7
Gribben, J.G.8
Nadler, L.M.9
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17
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0025951891
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Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
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of special interest
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of special interest Liu YJ, Zhang J, Lane PJ, Chan EY, MacLennan IC. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens. Eur J Immunol. 21:1991;2951-2962.
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Liu, Y.J.1
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MacLennan, I.C.5
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18
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0026670190
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In situ studies of the primary immune response to (4-hydroxy 3-nitrophenyl) acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers
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Jacob J, Kelsoe G. In situ studies of the primary immune response to (4-hydroxy 3-nitrophenyl) acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers. J Exp Med. 176:1992;679-687.
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Jacob, J.1
Kelsoe, G.2
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19
-
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0028064578
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Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
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of special interest. Describes that antigen activated B cells migrate to the T-cell zones.
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Cyster JG, Hartley SB, Goodnow CC. Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire. of special interest Nature. 371:1994;389-395 Describes that antigen activated B cells migrate to the T-cell zones.
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Cyster, J.G.1
Hartley, S.B.2
Goodnow, C.C.3
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21
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0028789148
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Anatomy of autoantibody production: Dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice
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of special interest. FasL limits autoantibody production in the T-cell zones where T-cell dependent B-cell activation occurs.
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Jacobsen BA, Panka DJ, Nguyen K, Erikson J, Abbas AK, Marshak-Rothstein A. Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice. of special interest Immunity. 3:1995;509-519 FasL limits autoantibody production in the T-cell zones where T-cell dependent B-cell activation occurs.
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Jacobsen, B.A.1
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Abbas, A.K.5
Marshak-Rothstein, A.6
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22
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0028961269
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Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro
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Decker DJ, Linton PJ, Zaharevitz S, Biery M, Gingeras TR, Klinman NR. Defining subsets of naive and memory B cells based on the ability of their progeny to somatically mutate in vitro. Immunity. 2:1995;195-203.
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Decker, D.J.1
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Biery, M.4
Gingeras, T.R.5
Klinman, N.R.6
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23
-
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0028939698
-
+ memory T cells contain preformed CD40-ligand (gp39) that has rapid transient surface expression on activation via the T cell receptor complex
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of special interest. Describes that T cells are heterogeneous with regard to the expression of CD40L in vivo.
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+ memory T cells contain preformed CD40-ligand (gp39) that has rapid transient surface expression on activation via the T cell receptor complex. of special interest J Exp Med. 181:1995;1293-1301 Describes that T cells are heterogeneous with regard to the expression of CD40L in vivo.
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Casamayor-Palleja, M.1
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24
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0029046321
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CD40 ligand independent B cell activation revealed by CD40-ligand deficient T cell clones: Evidence for distinct activation requirements for antibody formation and B cell proliferation
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Lane P, Burdet C, McConnell F, Lanzavecchia A, Padovan E. CD40 ligand independent B cell activation revealed by CD40-ligand deficient T cell clones: evidence for distinct activation requirements for antibody formation and B cell proliferation. Eur J Immunol. 25:1995;1788-1793.
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Padovan, E.5
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25
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0028447437
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The immune response in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation
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Kawabe T, Naka T, Yoshida K, Suematsu S, Yoshida N, Kishimoto T, Kikutani H. The immune response in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity. 1:1994;167-178.
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Kawabe, T.1
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Suematsu, S.4
Yoshida, N.5
Kishimoto, T.6
Kikutani, H.7
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26
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0028486131
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Mice deficient for the CD40 ligand
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Xu J, Foy TM, Laman JD, Waldschmidt TJ, Elsemore J, Noelle RJ, Flavell RA. Mice deficient for the CD40 ligand. Immunity. 1:1994;423-431.
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Xu, J.1
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Noelle, R.J.6
Flavell, R.A.7
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27
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0029034495
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The CD40 ligand expressed by human B cells costimulates B cell responses
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Grammer, A.C.1
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Lipsky, P.E.6
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28
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0029064680
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Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice
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of special interest. T cell dependent responses are impaired in CD19-deficient mice and this is associated with lack of germinal centers.
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Rickert RC, Rajewsky K, Ross J. Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice. of special interest Nature. 376:1995;352-355 T cell dependent responses are impaired in CD19-deficient mice and this is associated with lack of germinal centers.
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Nature
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Rickert, R.C.1
Rajewsky, K.2
Ross, J.3
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29
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0029094609
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Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule
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of special interest. See annotation [28].
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Engel P, Zhou LJ, Ord DC, Sato S, Koller B, Tedder TF. Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule. of special interest Immunity. 3:1995;39-50 See annotation [28].
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Engel, P.1
Zhou, L.J.2
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Sato, S.4
Koller, B.5
Tedder, T.F.6
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0028958669
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31
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0028227203
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Capra, J.D.6
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32
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0028953096
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Facultative role of germinal centers and T cells in the somatic diversification of lgVH genes
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of special interest. This paper describes the dissociation of geminal centers from somatic mutation.
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Miller C, Stedra J, Kelsoe G, Cemy J. Facultative role of germinal centers and T cells in the somatic diversification of lgVH genes. of special interest J Exp Med. 181:1995;1319-1331 This paper describes the dissociation of geminal centers from somatic mutation.
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Miller, C.1
Stedra, J.2
Kelsoe, G.3
Cemy, J.4
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33
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0028983212
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Ig VH hypermutation is absent in the germinal centers of aged mice
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of special interest. Describes that old mice have less somatic mutation in their B cells following immunization.
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Miller C, Kelsoe G. Ig VH hypermutation is absent in the germinal centers of aged mice. of special interest J Immunol. 155:1995;3377-3384 Describes that old mice have less somatic mutation in their B cells following immunization.
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Miller, C.1
Kelsoe, G.2
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Han S, Hathcock K, Zheng B, Kepler TB, Hodes R, Kelsoe G. Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. J Immunol. 155:1995;556-567.
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Han, S.1
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Hodes, R.5
Kelsoe, G.6
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35
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0028891504
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Isolation and characteristics of tonsil centroblasts with reference to Ig class switching
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Feuillard J, Taylor D, Casamayor-Palleja M, Johnson GD, MacLennan IC. Isolation and characteristics of tonsil centroblasts with reference to Ig class switching. Int Immunol. 7:1995;121-130.
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Feuillard, J.1
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Johnson, G.D.4
MacLennan, I.C.5
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36
-
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0029055061
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Generation of memory B cells and plasma cells in vitro
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of special interest. Describes that plasma cell differentiation is inhibited by CD40L.
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Arpin C, Dechanet J, Van Kooten C, Merville P, Grouard G, Briere F, Banchereau J, Liu YJ. Generation of memory B cells and plasma cells in vitro. of special interest Science. 268:1995;720-722 Describes that plasma cell differentiation is inhibited by CD40L.
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Arpin, C.1
Dechanet, J.2
Van Kooten, C.3
Merville, P.4
Grouard, G.5
Briere, F.6
Banchereau, J.7
Liu, Y.J.8
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37
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0029014435
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Antigen-induced B-cell death and elimination during germinal-centre immune responses
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of special interest. Antigen-reactive germinal center B cells can be deleted by soluble antigen.
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Shokat KM, Goodnow CC. Antigen-induced B-cell death and elimination during germinal-centre immune responses. of special interest Nature. 375:1995;334-338 Antigen-reactive germinal center B cells can be deleted by soluble antigen.
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Shokat, K.M.1
Goodnow, C.C.2
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38
-
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0029059370
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Soluble antigen can cause enhanced apoptosis of germinal-centre B cells [see comments]
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of special interest. See annotation [37].
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Pulendran B, Kannourakis G, Nouri S, Smith KG, Nossal GJ. Soluble antigen can cause enhanced apoptosis of germinal-centre B cells [see comments]. of special interest Nature. 375:1995;331-334 See annotation [37].
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Nature
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Pulendran, B.1
Kannourakis, G.2
Nouri, S.3
Smith, K.G.4
Nossal, G.J.5
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39
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0029157239
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Soluble antigen can impede affinity maturation and the germinal center reaction but enhance extrafollicular immunoglobulin production
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Pulendran B, Smith KG, Nossal GJ. Soluble antigen can impede affinity maturation and the germinal center reaction but enhance extrafollicular immunoglobulin production. J Immunol. 155:1995;1141-1150.
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Pulendran, B.1
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0023892588
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Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones
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41
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0028964162
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Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2
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