Met-enkephalin inhibits 5-hydroxytryptamine release from the rat ventral spinal cord via δ opioid receptors

Neuropharmacology

Volumn 35, Issue 6, 1996, Pages 743-749

  Franck, J ^a,c   Nylander, I ^b   Rosen A ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c Karolinska Insititute   (Sweden)

Author keywords

( ) trans (1S,2S) U 50488; 5,7 Dihydroxytryptamine; 5 Hydroxytryptamine; DAMGO; DPDPE; ICI 174,864; met enkephalin; Naloxonazine; Nor binaltorphimine; Opioid receptors; Spinal cord slices (ventral)

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; 5,7 DIHYDROXYTRYPTAMINE; DELTA OPIATE RECEPTOR; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; METENKEPHALIN; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE; NALOXONAZINE; NORBINALTORPHIMINE; OPIATE AGONIST; OPIATE ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONIN RELEASE; SPINAL CORD; TISSUE SLICE;

EID: 0030175125     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(96)00039-1     Document Type: Article

References (35)

1. Arvidsson U., Dado R. J., Riedl M., Lee J. -H., Law P. Y., Loh H. H., Elde R. and Wessendorf M. W. (1995) δ-Opioid receptor immunoreactivity: distribution in brainstem and spinal cord, and relationship to biogenic amines and enkephalin. J. Neurosci. 15: 1215-1235.
2. Baumgarten H. G., Björklund A., Lachenmayer L. and Nobin A. (1973) Evaluation of the effects of 5,7-dihydroxytryptamine on serotonin and catecholamine neurons in the rat CNS. Acta Physiol. Scand. suppl. 391: 1-19.
3. Bergström L., Christensson I., Folkesson R., Stenström B. and Terenius L. (1983) An ion exchange chromatography and radioimmunoassay procedure for measuring opioid peptides and substance P. Life Sci. 33: 1613-1619.
4. Bowker R. M., Steinbusch H. W. and Coulter J. D. (1981) Serotonergic and peptidergic projections to the spinal cord demonstrated by a combined retrograde HRP histochemical and immunocytochemical staining method. Brain Res. 211: 412-417.
5. Chan-Palay V., Jonsson G. and Palay S. L. (1978) Serotonin and substance P coexist in neurons of the rat's central nervous system. Proc. natn. Acad. Sci. U.S.A. 75: 1582-1586.
6. 5)enkephalin. Neuropeptides 5: 311-314.
7. Cruciani R. A., Lutz R. A., Munson P. J. and Rodbard D. (1987) Naloxonazine effects on the interaction of enkephalin analogs with mu-1, mu and delta opioid binding sites in rat brain membranes. J. Pharmacol exp. Ther. 242: 15-20.
8. Emson P. C., Gilbert R. F. T., Bennett G. W., Marsden C. A. and Hunt S. P. (1983) The coexistence of thyrotropin-releasing hormone and substance P in bulbospinal serotonergic neurones. In: Thyrotropin-releasing Hormone (Griffiths E.C. and Bennett G.W., Eds), pp. 33-43. Raven Press, New York.
9. Franck J., Fried G. and Brodin E. (1989) Substance P enhances the release of endogenous serotonin from rat ventral spinal cord. Eur. J. Pharmacol. 174: 85-90.
10. Franck J., Brodin E., Fried K., Rosén A., Yamamoto Y. and Fried G. (1991) The effect of selective serotonergic neurotoxin treatment on tachykinin levels in the rat ventral spinal cord. Neuroscience 2: 339-345.
11. Franck J., Brodin E. and Fried G. (1993) Differential release of endogenous 5-hydroxytryptamine, substance P and neurokinin A from rat ventral spinal cord in response to electrical stimulation. J. Neurochem. 61: 704-711.
12. Gillan M. G. C. and Kosterlitz H. W. (1982) Spectrum of the mu-, delta-and kappa-binding sites in homogenates of rat brain. Br. J. Pharmacol 77: 461-469.
13. Glazer E. J., Steinbusch H. W. M., Verhofstad A. and Basbaum A. I. (1981) Serotonin neurons in nucleus raphe dorsalis and paragigantocellularis of the cat contain enkephalin. J. Physiol. (Paris) 77: 241-245.
14. 4 Gly-ol)-enkephalin (DAGO). Neuropeptides 5: 383-386.
15. Holstege J. C. and Kuypers H. G. J. M. (1987) Brainstem projections to spinal motoneurons: an update. Neuroscience 23: 809-821.
16. Hunt S. P. and Lovick T. A. (1982) The distribution of serotonin, met-enkephalin and β-liipotropin-like immunoreactivity in neuronal perikarya of the cat brain stem. Neurosci. Lett. 30: 139-145.
17. Hökfelt T., Ljungdahl Å., Steinbusch H., Verhofstad A., Nilson G., Brodin E., Pernow B. and Goldstein M. (1978) Immunohistochemical evidence of substance P-like immunoreactivity in some 5-hydroxytryptamine containing neurons in the rat central nervous system. Neuroscience 3: 517-538.
18. Höllt V. (1986) Opioid peptide processing and receptor selectivity. A. Rev. Pharmacol. Toxicol. 26: 59-77.
19. 3H-serotonin from tissue slices of rat ventral spinal cord. Acta Physiol. Scand. 137: 63-71.
20. Jacobs B. L. and Azmitia E. (1992) Structure and function of the brain serotonergic system. Physiological Rev. 72: 165-229.
21. James I. F., Chavkin C. and Goldstein A. (1982) Preparation of brain membranes containing a single type of opioid receptor highly selective for dynorphin. Proc. natn. Acad. Sci. U.S.A. 79: 7570-7574.
22. Johansson O., Hökfelt T., Pernow B., Jeffcoate S. L., White N., Steinbusch H. W. M., Verhofstad A. A. J., Emson P. C. and Spindel E. (1981) Immunohistochemical support for three putative transmitters in one neuron: coexistence of 5-hydroxytryptamine, substance P-and thyrotropin releasing hormone-like immunoreactivity in medullary neurons projecting to the spinal cord. Neuroscience 6: 1857-1881.
23. Mansour A., Fox C. A., Akil H. and Watson S. J. (1995) Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications. Trends Neurosci. 18: 22-29.
24. Martin W. R., Eades C. G., Thompson J. A., Huppler R. E. and Gilbert P. E. (1976) The effects of morphine-and nalorphine-like drugs in the dependent and morphine dependent chronic spinal dog. J. Pharmacol. exp. Ther. 197: 517-532.
25. Melander T., Hökfelt T. and Rökaeus Å. (1986) Distribution of galanin-like immunoreactivity in the rat central nervous system. J. comp. Neurol. 248: 475-517.
26. Mitchell R. and Fleetwood-Walker S. (1981) Substance P, but not TRH, modulates the 5-HT autoreceptor in ventral lumbar spinal cord. Eur. J. Pharmacol. 76: 119-120.
27. Nylander I. and Terenius L. (1987) Dopamine receptors mediate alterations in striato-nigral dynorphin and substance P pathways. Neuropharmacology 26: 1295-1302.
28. Nylander I., Vlaskovska M. and Terenius L. (1995) The effects of morphine treatment and morphine withdrawal on the dynorphin and enkephalin systems in Sprague-Dawley rats. Psychopharmacology, in press.
29. Pert C. and Snyder S. (1973) Opiate receptor: demonstration in nervous tissue. Science 179: 1011-1014.
30. Portoghese P. S., Lipowski A. W. and Takemori A. E. (1987) Binaltorphimine and nor-binaltorphimine, potent and selective kappa-opioid receptor antagonists. Life Sci. 40: 1287-1292.
31. Ramabadran K., Bansinath M., Turndorf H, and Puig M. M. (1991) Kappa-opiate agonist-induced inhibition of gastrointestinal transit in different strains of mice. Pharmacology 42: 97-102.
32. Sharp T., Bramwell S. R. and Grahame-Smith D. G. (1990) Release of endogenous 5-hydroxytryptamine in rat ventral hippocampus evoked by electrical stimulation of the dorsal raphe nucleus as detected by microdialysis:sensitivity to tetrodotoxin, calcium and calcium antagonists. Neuroscience 39: 629-637.
33. 3H)etorphin to rat brain homogenate. Proc. natn. Acad. Sci. U.S.A. 70: 1947-1949.
34. Terenius L. (1973) Stereospecific interaction between narcotic analgesics and a synaptic plasma membrane fraction of rat cerebral cortex. Acta Pharmacol. Toxicol. 32: 317-320.
35. Udenfriend S. and Kilpatrick L. (1984) Proenkephalin and the