[Methyl-Carbon-11]Thymidine for in Vivo Measurement of Cell Proliferation

Journal of Nuclear Medicine

Volumn 37, Issue 6, 1996, Pages 1048-1052

  Goethals, Patrick ^a   Lameire, Norbert ^b   Van Eijkeren, Marc ^b   Kesteloot, Dirk ^b   Thierens, Hubert ^b   Dams, Richard ^b  

^a GHENT UNIVERSITY   (Belgium)

^b NONE

Author keywords

Cell proliferation; Positron emission tomography; Thymidine

Indexed keywords

CARBON; DIAGNOSTIC AGENT; DRUG DERIVATIVE; METHYLTHYMIDINE; THYMIDINE; THYMINE;

ANIMAL; ARTICLE; CELL DIVISION; COMPUTER ASSISTED EMISSION TOMOGRAPHY; LARGE INTESTINE; LIVER; LIVER RESECTION; MALE; METABOLISM; PILOT STUDY; RAT; TISSUE DISTRIBUTION; WISTAR RAT;

ANIMALS; CARBON RADIOISOTOPES; CELL DIVISION; HEPATECTOMY; INTESTINE, LARGE; LIVER; MALE; PILOT PROJECTS; RATS; RATS, WISTAR; THYMIDINE; THYMINE; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0030162615     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Shields A, Lim K, Grierson J, Link Y, Krohn KA. Utilization of labeled thymidine in DNA synthesis: Studies for PET. J Nucl Med 1990;31:337-342.
2. 11C]thymidine and its metabolites in head and neck tumors. J Nucl Med 1995;36:880-882.
3. 11C]thymidine. Appl Radial Isot 1992;43:952-954.
4. 13N-ammonia by human tumors as studied by positron emission tomography. Br J Radiol 1982;55:797-804.
5. 13N-ammonia as tumor tracer. Acta Oncol 1987;26:105-111.
6. Strauss LG, Conti PS. The applications of PET in clinical oncology. J Nucl Med 1991;32:623-647.
7. 3H-Thymidine-labeling index as prognostic indicator in node-positive breast cancer. J Clin Oncol 1990;8:1321-1326.
8. De Reuck J, Sieben G, De Coster W, Roels H, vander Eecken H. Cytophotometric DNA determination in human oligodendoglial tumors. Histopathology 1990;4:225-232.
9. Martiat Ph, Ferrant A, Labar D, Cogncau M, Bol A, Michel C, Michaux JL, Sokal G In vivo measurement of carbon-11-thymidine uptake in non-Hodgkin's lymphomas using PET. J Nucl Med 1988;29:1633-1637.
10. 11C-thymidine uptake in tumors of the head and neck using positron emission tomography. Acta Oncul 1992;31:539-543.
11. Shaw T, Mac Phee DG. Rapid and complete degradation of thymidine by human peripheral blood platelets: implications for genoloxicity assays. Mut Res 1986;163: 75-80.
12. Vander Borght T, De Maeght S, Labar D, Goethals P, Pauwels S, van Eijkeren M. Comparison of thymidine labeled in methyl group and in 2C-position in human PET studies [Abstract]. Eur J Med Nucl Med 1992;19:578.
13. 11thymidine. Br J Radiol 1994;67:292-295.