Active expression of Gγ globin gene on chromosome 11 with Yunnanese (Aγδβ)0-thalassemia deletion in MEL cells

Science in China, Series C: Life Sciences

Volumn 39, Issue 3, 1996, Pages 329-336

  Zhang, Junwu ^a   Qiao, Jun ^b   Song, Wenfeng ^c   Qiu, Zhiming ^c  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b Chinese Japanese Friendship Hospital   (China)

^c KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

(A )0 thalassemia; Cell fusion; Fetal globin gene; Gene expression; Mouse erythroleukemia cells

Indexed keywords

GLOBIN;

ADULT; ANIMAL; ARTICLE; CELL CULTURE; CELL FUSION; CELL LINE; CHROMOSOME 11; EXPERIMENTAL LEUKEMIA; GENE DELETION; GENE EXPRESSION; GENETICS; HUMAN; MALE; MOUSE; PATHOLOGY; THALASSEMIA;

ADULT; ANIMALS; CELL FUSION; CELL LINE; CHROMOSOMES, HUMAN, PAIR 11; GENE DELETION; GENE EXPRESSION; GLOBINS; HUMANS; LEUKEMIA, EXPERIMENTAL; MALE; MICE; THALASSEMIA; TUMOR CELLS, CULTURED;

EID: 0030161927     PISSN: 10069305     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Stamatoyannopoulos, G., Nienhuis, A. W., The Molecular basis of Blood Diseases, 1st ed., Philadelphia: WB Saunders Co., 1987, 66-105.
2. 0-thalassemia deletion in a Chinese family, Blood, 1993, 81(6): 1624.
3. Qiao, J., Liu, Y. Q., Sun, Y. P., A new procedure for foundation of the B lymphocyte cell lines by transformation of small quantity of whoel blood with EB virus, Chinese Journal of Experimental and Clinic Immunology (in Chinese), 1990, 2(1): 2.
4. Papayannopoulou, T., Brice, M., Stamatoyannopoulos, Analysis of human hemoglobin switching in MELxhuman fetal erythroid cell hybrids, Cell, 1986, 46(3): 469.
5. Papayannopoulou, T., Brice, M., Yokochi, T. et al., Anti-HEL cell monoclonal antibodies recognize determinants that are also present in hemopoietic progenitors, Blood, 1984, 63(2): 326.
6. Stamatoyannopoulos, G., Farquhar, M., Lindsley, D. et al., Monoclonal antibodies specific for globin chains, Blood, 1983, 6: 530.
7. Wang, L. F., Pan, H. Z., Zhang, J. W. et al., Basic Techniques in Molecular Biology (in Chinese), Beijing: Physiological Sciences Publication House, 1992, 48-68.
8. Stamatoyannopoulos, G., Josephson, B., Zhang, J. W. et al., Developmental regulation of human γ-globin genes in transgenic mice, Molecular and Cellular Biology, 1993, 13(11): 7636.
9. Enver, T., Raith, N., Stamatoyannopoulos, G. et al., Developmental regulation of human fetal to adult globin gene switching, Nature, 1990, 334(6264): 309.
10. Morley, B. J., Abbott, G. A., Wood, W. G., Regulation of human fetal and adult globin genes in mouse erythroleukemia cells, Blood, 1991, 78(5): 1355.
11. Orkin, S. H , Globin gene regulation and switching: circa 1990, Cell, 1990, 63(4): 665.
12. Takegawa, S., Brice, M., Papayannopoulos, T. et al., Only adult hemoglobin is produced in fetal nonerythroid MEL hybrids, Blood, 1986, 68(6): 1384.
13. Papayannopoulou, T., Enver, T., Stamatoyannopoulos, G. et al., Activation of developmentally mutated human globin genes by cell fusion, Science, 1988. 252: 1056,
14. Huisman, T. H. J., Schroeder, W. A., Efremov, G. D. et al., The present status of heterogeneity of fetal hemoglobin in β-thalassemia: an attempt to unify some observations in thalassemia and related conditions, Ann. N. Y. Acad. Sci., 1974, 232: 107.
15. 0-thalassemia and hereditary persistence of fetal hemoglobin: Implications for control of γ-globin gene expression in man, Proc. Natl. Acad. Sci. USA, 1983, 80(22): 6937.
16. Behringer, R. R., Ryan, T. M., Palmiter, R. D. et al., Human γ- to β-globin gene switching in transgenic mice, Genes and Dev., 1990, 4(3): 380.