Cytokine Signaling in Mesothelial Cells: Receptor Expression Closes the Autocrine Loop

American Journal of Respiratory Cell and Molecular Biology

Volumn 14, Issue 6, 1996, Pages 505-507

  Gerwin, Brenda I ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR;

EPITHELIUM; EPITHELIUM CELL; GENE EXPRESSION; GENETICS; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

CYTOKINES; EPITHELIAL CELLS; EPITHELIUM; GENE EXPRESSION; RECEPTORS, CYTOKINE; SIGNAL TRANSDUCTION;

EID: 0030161476     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.14.6.8652178     Document Type: Review

References (27)

1. Fujino, S., A. Yokoyama, N. Kohno, and K. Hiwada. 1996. Interleukin-6 is an autocrine growth factor for normal human pleural mesothelial cells. Am. J. Respir. Cell Mol. Biol. 14:508-515.
2. Heinrich, P. C., L. Graeve, S. Rose-John, J. Schneider-Mergener, E. Dittrich, A. Erren, C. Gerhartz, U. Hemann, C. Lutticken, U. Wegenka, O. Weiergraber, and F. Horn. 1995. Membrane-bound and soluble interleukin-6 receptor: studies on structure, regulation of expression, and signal transduction. Ann. NY Acad. Sci. 762:222-237.
3. Miki, S., M. Iwano, Y. Miki, M. Yamamoto, B. Tang, K. Yokokawa, T. Sonoda, T. Hirano, and T. Kishimoto. 1989. Interleukin-6 (IL-6) functions as an in vitro autocrine growth factor in renal cell carcinomas. FEBS Lett. 250:607-610.
4. Lanfrancone, L., D. Boraschi, P. Ghiara, B. Falini, F. Grignani, G. Peri, A. Mantovani, and P. G. Pelicci. 1992. Human peritoneal mesothelial cells produce many cytokines (granulocyte colony-stimulating factor [CSF], granulocyte-monocyte-CSF, macrophage-CSF, interleukin-1 [IL-1], and IL-6) and are activated and stimulated to grow by IL-1. Blood 80:2835-2842.
5. Jonjic, N., G. Peri, S. Bernasconi, F. L. Sciacca, F. Colotta, P. Pelicci, L. Lanfrancone, and A. Mantovani. 1992 Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells. J. Exp. Med. 176:1165-1174.
6. Demetri, G. D., B. W. Zenzie, J. G. Rheinwald, and J. D. Griffin. 1989. Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro. Blood 74:940-946.
7. Schmitter, D., B. Lauber, B. Fagg, and R. A. Stahel. 1992. Hematopoietic growth factors secreted by seven human pleural mesothelioma cell lines: interleukin-6 production as a common feature. Int. J. Cancer 51:296-301.
8. Ng, S. B., Y. H. Tan, and G. R. Guy. 1994 Differential induction of the interleukin-6 gene by tumor necrosis factor and interleukin-1. J. Biol. Chem. 269:19021-19027.
9. Hirano, T., T. Matsuda, and K. Nakajima. 1994 Signal transduction through gp130 that is shared among the receptors for the interleukin 6 related cytokine subfamily. Stem. Cells (Dayt). 12:262-277.
10. Sehgal, P. B., L. Wang, R. Rayanade, H. Pan, and L. Margulies. 1995. Interleukin-6-type cytokines. Ann. NY Acad. Sci. 762:1-14.
11. Murakami, M., M. Hibi, N. Nakagawa, T. Nakagawa, K. Yasukawa, K. Yamanishi, T. Taga, and T. Kishimoto. 1993. IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase. Science 260:1808-1810.
12. Mackiewicz, A., H. Schooltink, P. C. Heinrich, and S. Rose-John. 1992. Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute-phase proteins. J. Immunol. 149:2021-2027.
13. Ihle, J. N. 1995 Cytokine receptor signalling. Nature 377:591-594.
14. Ihle, J. N. 1996. STATs: signal transducers and activators of transcription. Cell 84:331-334.
15. Stahl, N., T. J. Farruggella, T. G. Boulton, Z. Zhong, J. E. Darnell, Jr., and G. D. Yancopoulos. 1995 Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science 267:1349-1353.
16. Narazaki, M., B. A. Witthuhn, K. Yoshida, O. Silvennoinen, K. Yasukawa, J. N. Ihle, T. Kishimoto, and T. Taga. 1994. Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130. Proc. Natl. Acad. Sci. USA 91:2285-2289.
17. Murakami, M., M. Narazaki, M. Hibi, H. Yawata, K. Yasukawa, M. Hamaguchi, T. Taga, and T. Kishimoto. 1991. Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family. Proc. Natl. Acad. Sci. USA 88:11349-11353.
18. Kinoshita, S., S. Akira, and T. Kishimoto 1992. A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6. Proc. Natl. Acad. Sci. USA 89:1473-1476.
19. Heintz, N. H., Y. M. Janssen, and B. T. Mossman. 1993. Persistent induction of c-fos and c-jun expression by asbestos. Proc. Natl. Acad. Sci. USA 90:3299-3303.
20. Janssen, Y. M., N. H. Heintz, and B. T. Mossman. 1995. Induction of c-fos and c-jun proto-oncogene expression by asbestos is ameliorated by N-acetyl-L-cysteine in mesothelial cells. Cancer Res. 55:2085-2089.
21. Janssen, Y. M., N. H. Heintz, J. P. Marsh, P. J. Borm, and B. T. Mossman. 1994. Induction of c-fos and c-jun proto-oncogenes in target cells of the lung and pleura by carcinogenic fibers. Am. J. Respir. Cell Mol. Biol. 11:522-530.
22. Quinlan, T. R., J. P. Marsh, Y. M. Janssen, K. O. Leslie, D. Hemenway, P. Vacek, and B. T. Mossman. 1994. Dose-responsive increases in pulmonary fibrosis after inhalation of asbestos. Am. J. Respir. Crit. Care Med. 150:200-206.
23. Lord, K. A., A. Abdollahi, S. M. Thomas, M. DeMarco, J. S. Brugge, B. Hoffman-Liebermann, and D. A. Liebermann. 1991. Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation. Mol. Cell Biol. 11:4371-4379.
24. Grafstrom, R. C., K. Sundqvist, J. M. Dypbukt, and C. C. Harris. 1987. Pathobiological effects of aldehydes in cultured human bronchial cells. In Relevance of N-Nitroso Compounds to Human Cancer. H. Bartsch, J. K. O'Neill, and R. Schulte-Hermann, editors. Oxford University Press, United Kingdom. 443-445.
25. Nagasawa, H. and J. B. Little. 1988. Radiosensitivities of ten apparently normal human diploid fibroblast strains to cell killing, G2-phase chromosomal aberrations, and cell cycle delay. Cancer Res. 48:4535-4538.
26. Coffer, P., C. Lutticken, A. van Puijenbroek, M. Klop-de Jonge, F. Horn, and W. Kruijer. 1995. Transcriptional regulation of the junB promoter: analysis of STAT-mediated signal transduction. Oncogene 10:985-994.
27. Lutticken, C., P. Coffer, J. Yuan, C. Schwartz, E. Caldenhoven, C. Schindler, W. Kruijer, P. C. Heinrich, and F. Horn. 1995. Interleukin 6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction. FEBS Lett. 360:137-143.