TNFα Gene and Protein Expression in Alveolar Macrophages in Acute and Chronic Hyperoxia-induced Lung Injury

American Journal of Respiratory Cell and Molecular Biology

Volumn 14, Issue 6, 1996, Pages 548-555

  Horinouchi, Hirohisa ^b   Wang, Chi Chung ^c   Shepherd, Kenneth E ^c   Jones, Rosemary ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

LIPOPOLYSACCHARIDE; MESSENGER RNA; OXYGEN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; CAPILLARY; CELL COUNT; CHEMICALLY INDUCED DISORDER; CYTOLOGY; GENE EXPRESSION; GENETICS; HYPEROXIA; IN SITU HYBRIDIZATION; LUNG ALVEOLUS MACROPHAGE; LUNG DISEASE; LUNG LAVAGE; MALE; METABOLISM; NORTHERN BLOTTING; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; SENSITIVITY AND SPECIFICITY; SPRAGUE DAWLEY RAT; TIME; ULTRASTRUCTURE;

ANIMALS; BLOTTING, NORTHERN; BRONCHOALVEOLAR LAVAGE FLUID; CAPILLARIES; CELL COUNT; GENE EXPRESSION; HYPEROXIA; IN SITU HYBRIDIZATION; LIPOPOLYSACCHARIDES; LUNG DISEASES; MACROPHAGES, ALVEOLAR; MALE; OXYGEN; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030160342     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.14.6.8652183     Document Type: Article

References (51)

1. Jones, R. C., W. M. Zapol, and L. Reid. 1984. Pulmonary artery remodeling and pulmonary hypertension after exposure to hyperoxia for 1 days: a morphometric and hemodynamie study. Am. J. Pathol. 117:273-285.
2. 1H-thymidine pulse labeling of intimal, medial and adventitial cells in microvessels and at the hilum. Am. Rev. Respir. Dis. 140:1471-1477.
3. Powell, P. P., C. C. Wang, and R. C. Jones. 1992. Differential regulation of the genes encoding platelet-derived growth factor receptor and its ligand in rat lung during microvascular and alveolar wall remodeling in hyperoxia. Am. J. Respir. Cell Mol. Biol. 7:278-285.
4. Jones, R. C., W. M. Zapol, and L. Reid. 1985. Oxygen toxicity and restructuring of pulmonary arteries - a morphometric study. The response to 4 weeks' exposure to hyperoxia and return to breathing air. Am. J. Pathol. 121:212-223.
5. Jones, R. C. 1992. Ultrastructural analysis of contractile cell development in hyperoxic pulmonary hypertension: fibroblasts and intermediate cells selectively reorganize nonmuscular segments. Am. J. Pathol. 141:1491-1505.
6. Jones, R. C. 1993. Role of interstitial fibroblasts and intermediate cells in microvascular wall remodeling in pulmonary hypertension. Eur. Respir. Rev. 3:569-575.
7. Crapo, C. D., B. E. Barry, H. A. Foscue, and J. Shelburne. 1980. Structural and biochemical changes in rat lungs occurring during exposures to lethal and adaptive dose of oxygen. Am. Rev. Respir. Dis, 120:123-143.
8. Powell, P. P., M. Klagsbrun, J. A. Abraham, and R. C. Jones. 1993. Eosinophils expressing heparin-hinding EGF like growth factor mRNA localize around lung microvessels in pulmonary hypertension. Am. J. Pathol. 143:784-793.
9. Jacobson, M., C. C. Wang, H. H. Horinouchi, K. E. Shepherd, and R. C. Jones. 1995. Regulation of PDGF-BB protein expression by AMs in pulmonary hypertension. Am. J. Respir. Crit. Care Med. 151:A734. (Abstr.)
10. Wang, C. C., H. Horinouchi, K. E. Shepherd, and R. C. Jones. 1995. Regulation of basic fibroblast ligand (bFGF) and receptor (FGFR) gene expression in pulmonary hypertension, and localization of protein. Am. J. Respir. Crit. Care Med. 151:A734. (Abstr.)
11. Pierce, G. F. 1990. Macrophages: important physiologic and pathologic sources of polypeptide growth factors. Am. J. Respir. Cell Mol. Biol. 2:233-234.
12. Kumar, R. K., R. A. Bennett, and A. R. Brody. 1988. A homologue of platelet-derived growth factor produced by rat alveolar macrophages. FASEB J. 2:2272-2277.
13. Shimokado, K., E. W. Reines, D. K. Madtes, T. B. Barrett, E. P. Benditt, and R. Ross. 1985. A significant part of macrophage derived growth factor consists of at least two forms of PDGF. Cell 43:277-286.
14. Higashiyama, S., J. A. Abraham, J. Miller, J. Fiddes, and M. Klagsbrun. 1991. A heparin-binding growth factor secreted by macrophage like cells that is related to EGF. Science 251:9936-9939.
15. Becker, S., R. B. Devlin, and J. S. Haskill. 1989. Differential production of tumor necrosis factor, macrophage colony stimulating factor, and interleukin 1 by human alveolar macrophages. J. Leukoc. Biol. 45:353-361.
16. Strieter, R. M., S. L. Kunkel, H. J. Showell, D. G. Remick, S. H. Phan, P. A. Ward, and R. M. Marks. 1989. Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-α, LPS, and IL-1β. Science 243:1467-1469.
17. Warren, J. S., K. R. Yabroff, D. G. Remick, S. L. Kankel, S. W. Chensue, R. G. Kunkel, K. J. Johnson, and P. Ward. 1989. TNF participates in pathogenesis of acute immune complex alveolitis in the rat. J. Clin. Invest. 84:1873-1882.
18. Ulich, T. R., L. R. Watson, S. Yin, K. Guo, P. Wang, H. Thang, and J. D. Castillo. 1991. The intratracheal administration of endotoxin and cytokines I. Characterization of LPS-induced IL-1 and TNF mRNA expression and the LPS-, IL-1, and TNF-induced inflammatory infiltrate. Am. J. Pathol. 138:1485-1496.
19. Vilcek, J., V. J. Pallombella, D. Henricksen-Destifano, C. Swenson, R. Feinman, M. Hirai, and M. Tsujimoto 1986. Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors. J. Exp. Med. 163:632-643.
20. Leibovich, S. J., P. J. Polverini, H. M. Shepard, D. M. Wiseman, V. Shively, and N. Nuseir. 1987. Macrophage-induced angiogenesis is mediated by tumor necrosis factor-α. Nature 329:630-632.
21. Moolenbeek, C. 1982. Obtaining alveolar macrophages from small laboratory rodents. Lab. Anim. 16:56-58.
22. van Nhieu, J. T., B. Misset, F. Lebargy, J. Carlet, S. F. Bernaudin. 1993. Expression of tumor necrosis factor a gene in alveolar macrophages from patients with the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 147:1585-1589.
23. Diamond, J. R., and I. Pesek. 1991. Glomerular tumor necrosis factor and interleukin I during acute aminonucleoside nephrosis - an immunohistochemical study. Lab. Invest. 64:21-28.
24. Yeh, H.-J., G. F. Pierce, and T. F. Deuel. 1987. Ultrastructural localization of a platelet-derived growth factor/v-sis-related protein(s) in cytoplasm and nucleus of simian sarcoma virus-transformed cells. Proc. Natl. Acad. Sci. USA 84:2317-2321.
25. Pangakos, F. S., and S. Kumar. 1994. Nuclear localization of tumor necrosis factor-alpha in human osteoblast-like cells. Biochem. Biophys. Res. Commun. 201:1445-1450.
26. Renko, M., N. Quarto, T. Morimoto, and D. B. Rifkin. 1990. Nuclear and cytoplasmic localization of different basic fibroblast growth factor species. J. Cell Physiol. 144:108-114.
27. Powell, P. P., and M. Klagsbrun. 1991. Three forms of rat basic fibroblast growth factor are made from a single mRNA and localize to the nucleus. J. Cell Physiol. 148:202-210.
28. Lewis, R. A., K. F. Austen, and R. J. Soberman. 1990. Leukotrienes and other products of the 5-lipooxygenase pathway. N. Engl. J. Med. 323:645-655.
29. Flory, C. M., M. L. Jones, B. F. Miller, and J. S. Warren. 1995. Regulatory role of tumor necrosis factor or and interleukin 1-β in monocyte chemoattractant protein-1-mediated pulmonary granuloma formation in the rat. Am. J. Pathol. 146:450-462.
30. Welty, S. E., J. L. Rivera, J. F. Elliston, C. V. Smith, T. Zeb, C. M. Ballantyne, C. A. Montgomery, and T. N. Hansen. 1993. Increases in lung tissue expression of intercellular adhesion molecule-1 are associated with hyperoxic lung injury and inflammation in mice. Am. J. Respir. Cell Mol. Biol. 9:393-400.
31. 2 regulates macrophage-derived tumor necrosis factor gene expression. J. Biol. Chem. 263:5380-5384.
32. Fiorentino, D. F., A. Z. Timothy, M. Howard, and A. O'Garra. 1991. IL-10 inhibits cytokine production by activated macrophages. J. Immunol. 147: 3815-3822.
33. Adamson, I. Y. R., and D. H. Bowden. 1980. Role of monocyte and interstitial cells in the generation of alveolar macrophages-2. Kinetic studies after carbon loading. Lab. Invest. 42:518-524.
34. Kobzik, L., J. J. Godleski, B. E. Barry, and J. D. Brain. 1988. Isolation and antigenic identification of hamster lung interstitial macrophages. Am. Rev. Respir. Dis. 138:908-914.
35. Lehnen, B. E., Y. E. Valdez, R. J. Sebring, N. M. Lehnen, G. C. Saunders, and J. A. Steinkamp. 1990. Airway intra-luminal macrophages: evidence of origin and comparisons to alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 3:377-391.
36. Sinkin, R. A., M. B. LoMonaco, J. N. Finkelstein, R. H. Watkins, C. Cox, and S. Horowitz. 1992. Increased fibronectin mRNA in alveolar macrophages following in vivo hyperoxia. Am. J. Respir. Cell Mol. Biol. 7:548-555.
37. Ulich, T. R. 1993. Tumor necrosis factor. In Cytokines of the Lung. J. Kelly, editor. Lung Biology in Health and Disease, Vol. 61. Marcel Dekker, New York. 307-332.
38. Marcho, Z., J. E. White, P. J. Higgins, and M. F. Tsan. 1991. Tumor necrosis factor enhances endothelial cell susceptibility to oxygen toxicity: role of glutathione Am. J. Respir. Cell Mol. Biol. 5:556-562.
39. Jensen, J. C., H. W. Pogrebniak, H. I. Pass, C. Buresh, M. J. Merino, D. Kauffman, D. Venzon, H. N. Langstein, and J. A. Norton. 1992. Role of tumor necrosis factor in oxygen toxicity. 72:1902-1907.
40. Bone, R. C. 1991. The pathogenesis of sepsis. Ann. Intern. Med. 115: 457-469.
41. Koltai, M., D. Hosford, and P. Braquet. 1992. Role of PAF and cytokines in microvascular tissue injury. J. Lab. Clin. Med. 119:461-466.
42. White, C. W., P. Ghezzi, C. A. Dinarello, S. A. Caldwell, I. F. McMurtry, and J. E. Repine. 1987. Recombinant tumor necrosis factor/cachectin and interleukin 1 pretreatment decreases lung oxidized glutathione accumulation, lung injury, and mortality in rats exposed to hyperoxia. J. Clin. Invest. 79:1868-1873.
43. Tsan, M. F., J. E. White, T. A. Santana, and C. Y. Lee. 1990. Tracheal insufflation of tumor necrosis factor protects rat against oxygen toxicity. J. Appl. Physiol. 68:1211-1219.
44. Ming, W. J., L. Bersani, and A. Mantovani. 1987. Tumor necrosis factor is chemotactic for monocytes and polymorphonuclear leukocytes. J. Immunol. 138:1469-1474.
45. Finotto, S., I. Ohno, J. S. Marshall, J. Gauldie, J. A. Denburg, J. Dolovich, D. A. Clark, and M. Jordana. 1994. TNFα production by eosinophils in upper airways inflammation (nasal polyposis). J. Immunol. 153: 2278-2289.
46. Xing, Z., H. Kirpalani, D. Torry, M. Jordana, and J. Gauldie. 1993. Polymorphonuclear leukocytes as a significant source of tumor necrosis factor-α in endotoxin-challenged lung tissue. Am. J. Pathol. 143:1009-1015.
47. Hajjar, K., D. P. Hajjar, R. L. Silverstein, and R. L. Nachman. 1987. Tumor necrosis factor release of platelet-derived growth factor from cultured endothelial cells. J. Exp. Med. 166:235-245.
48. Yoshizumi, M., S. Kourembanas, D. H. Temizer, R. P. Cambria, T. Quatermous, and M. E. Lee. 1992. Tumor necrosis factor increases transcription of the heparin-binding epidermal like growth factor gene in vascular endothelial cells. J. Biol. Chem. 267:9467-9469.
49. Kung, T. T., D. Stelts, J. A. Zurcher, H. Jones, S. P. Umland, W. Krentnee, R. W. Egan, and R. W. Chapman. 1995. Mast cells modulate allergic pulmonary eosinophilia in mice. Am. J. Respir. Cell Mol. Biol. 12:404-409.
50. O'Brien-Ladner, A. R., M. E. Nelson, B. D. Cowley, Jr., K. Bailey, and L. J. Wesselius. 1995. Hyperoxia amplifies TNFα production in LPS-stimulated human alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 12:275-279.
51. VanOtteren, G. M., T. S. Standiford, S. L. Kunkel, J. M. Danforth, and R. M. Strieter. 1995. Alterations in ambient oxygen tension modulate the expression of tumor necrosis factor and macrophage inflammatory protein-1 alpha from murine macrophages. Am J. Respir. Cell Mol. Biol. 13: 399-409.