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Volumn 5, Issue 3, 1996, Pages 400-409

Patient access to experimental drugs and AIDS clinical trial designs: Ethical issues

(2)  Schüklenk, Udo a   Hogan, Carlton a  

a NONE

Author keywords

[No Author keywords available]

Indexed keywords

NEW DRUG; PLACEBO;

EID: 0030158858     PISSN: 09631801     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0963180100007209     Document Type: Article
Times cited : (4)

References (15)
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    • Washington, DC: National Academy Press
    • US National Research Council. Social Impact of AIDS. Washington, DC: National Academy Press, 1993.
    • (1993) Social Impact of AIDS
  • 3
    • 0024576945 scopus 로고
    • The case for patient access to experimental therapies
    • Delaney M. The case for patient access to experimental therapies. Journal of Infectious Diseases 1989;159:416-9.
    • (1989) Journal of Infectious Diseases , vol.159 , pp. 416-419
    • Delaney, M.1
  • 4
    • 0029392838 scopus 로고
    • ACTG 175 and delta
    • Torres G. ACTG 175 and delta. Treatment Issues 1995;9(10):2-3.
    • (1995) Treatment Issues , vol.9 , Issue.10 , pp. 2-3
    • Torres, G.1
  • 5
    • 0023268502 scopus 로고
    • The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex
    • Fischl MA, Richman DD, Grieco MH, et al. The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. New England Journal of Medicine 1987;317:185-91; Richman DD, Fischl MA. Grieco MH, et al. The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. New England Journal of Medicine 1987;314:192-7.
    • (1987) New England Journal of Medicine , vol.317 , pp. 185-191
    • Fischl, M.A.1    Richman, D.D.2    Grieco, M.H.3
  • 6
    • 0023266214 scopus 로고
    • The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex
    • Fischl MA, Richman DD, Grieco MH, et al. The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. New England Journal of Medicine 1987;317:185-91; Richman DD, Fischl MA. Grieco MH, et al. The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. New England Journal of Medicine 1987;314:192-7.
    • (1987) New England Journal of Medicine , vol.314 , pp. 192-197
    • Richman, D.D.1    Fischl, M.A.2    Grieco, M.H.3
  • 7
  • 8
    • 17444378866 scopus 로고
    • A review of AZT multi center trial-data obtained under the Freedom of Information Act by Project Inform and ACT Up
    • Sonnabend J. A review of AZT multi center trial-data obtained under the Freedom of Information Act by Project Inform and ACT Up. AIDS Forum 1989;1(1):9-15.
    • (1989) AIDS Forum , vol.1 , Issue.1 , pp. 9-15
    • Sonnabend, J.1
  • 9
    • 0027491212 scopus 로고
    • Antiretroviral therapy for adult HIV-infected patients - Recommendations from a state-of-the-art conference
    • Sande MA, Arpener CCJ, Obiss CG, et al. Antiretroviral therapy for adult HIV-infected patients - recommendations from a state-of-the-art conference. Journal of the American Medical Association 1993;270:2583-9.
    • (1993) Journal of the American Medical Association , vol.270 , pp. 2583-2589
    • Sande, M.A.1    Arpener, C.C.J.2    Obiss, C.G.3
  • 10
    • 17444392004 scopus 로고    scopus 로고
    • The estimate is conservative, based on TAG's Summary of US Research Budget. When one adds the costs of the many industry trials, the effort of the MRC in Britain, INSERM in France, the Australian European Cooperative Group, etc., the amount is probably double this figure
    • The estimate is conservative, based on TAG's Summary of US Research Budget. When one adds the costs of the many industry trials, the effort of the MRC in Britain, INSERM in France, the Australian European Cooperative Group, etc., the amount is probably double this figure.
  • 11
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    • On stopping a trial before its time
    • [Anonymous]. On stopping a trial before its time. The Lancet 1993;342:1311-2.
    • (1993) The Lancet , vol.342 , pp. 1311-1312
  • 12
    • 17444386978 scopus 로고    scopus 로고
    • AOL PWA mailing list [privileged communication]
    • AOL PWA mailing list [privileged communication].
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    • Equipoise and the ethics of clinical research
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  • 14
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    • Pneumocystis carinii pneumonia is a common opportunistic infection in PWAs and the cause of most AIDS-related deaths
    • Pneumocystis carinii pneumonia is a common opportunistic infection in PWAs and the cause of most AIDS-related deaths.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.