The Role of MHC Class II Genes in Susceptibility and Resistance to Type I Diabetes Mellitus in the NOD Mouse

Hormone and Metabolic Research

Volumn 28, Issue 6, 1996, Pages 287-288

  McDevitt, H ^a   Singer, S ^a   Tisch, R ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

IDDM; MHC Class II Genes; NOD Mouse; Susceptibility

Indexed keywords

ANIMAL; ARTICLE; DISEASE PREDISPOSITION; FEMALE; GENE; GENETICS; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NONOBESE DIABETIC MOUSE; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; DIABETES MELLITUS, TYPE 1; DISEASE SUSCEPTIBILITY; FEMALE; GENES, MHC CLASS II; MICE; MICE, INBRED NOD; MICE, TRANSGENIC;

EID: 0030157684     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-979794     Document Type: Conference Paper

References (4)

1. + T cells in the pathogenesis of organ-specific autoimmune diseases. Immunology Today 16: 34-38 (1995)
2. d transgene prevents diabetes in non-obese diabetic mice by inducing regulatory T cells. Proc. Natl. Acad. Sci. USA 90: 9566-9570 (1993)
3. Tisch, R., X. D. Yang, S. M. Singer, R. S. Liblau, L. Fugger, H. O. McDevitt: Immune response to glutamic acid decarboxylase correlates with insulitis onset in non-obese diabetic mice. Nature 366: 72-75 (1993)
4. Todd, J. A., J. I. Bell, H. O. McDevitt: HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 329: 599-604 (1987)