The Tracheobronchial Vasculature: A Possible Role in Asthma

Microcirculation

Volumn 3, Issue 2, 1996, Pages 129-141

  Widdicombe, John ^a  

^a ST GEORGE S HOSPITAL   (United Kingdom)

Author keywords

Airway inflammation; Airway mucosa; Asthma; Bronchial vasculature; Tracheal vasculature

Indexed keywords

CANIS FAMILIARIS; CAVIA; ORYCTOLAGUS CUNICULUS; OVIS ARIES; RODENTIA;

CYTOKINE; HYPERTONIC SOLUTION; NEUROPEPTIDE;

AIRWAY RESISTANCE; ANIMAL; ASTHMA; BRONCHUS; BRONCHUS HYPERREACTIVITY; CAPILLARY PERMEABILITY; CELL JUNCTION; COLD; COMPARATIVE STUDY; DOG; DRUG EFFECT; EXUDATE; GUINEA PIG; HISTOLOGY; HUMAN; LUNG LAVAGE; METABOLISM; MICROCIRCULATION; MUCOSA; PATHOPHYSIOLOGY; PHYSIOLOGY; RABBIT; RAT; REVIEW; SHEEP; SPECIES DIFFERENCE; TRACHEA; VAGUS NERVE; VASCULARIZATION; VASODILATATION;

AIRWAY RESISTANCE; ANIMALS; ASTHMA; BRONCHI; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CAPILLARY PERMEABILITY; COLD; CYTOKINES; DOGS; EXUDATES AND TRANSUDATES; GUINEA PIGS; HUMANS; HYPERTONIC SOLUTIONS; INTERCELLULAR JUNCTIONS; MICROCIRCULATION; MUCOUS MEMBRANE; NEUROPEPTIDES; RABBITS; RATS; SHEEP; SPECIES SPECIFICITY; TRACHEA; VAGUS NERVE; VASODILATION;

EID: 0030155313     PISSN: 10739688     EISSN: None     Source Type: Journal    
DOI: 10.3109/10739689609148283     Document Type: Review

References (68)

1. Baier H, Moas R, Yerger L, Wanner A. (1986). In vivo estimation of tracheal wall water: effects of histamine and carbachol. J Appl Physiol 60: 1680-1685.
2. Baile EM, Sotres-Vega A, Pare PD. (1994). Airway blood flow and bronchovascular congestion in sheep. Eur Respir J 7: 1300-1307.
3. Barnes PJ. (1992). Airway NANC nerves and neuropeptides. In: Asthma. Basic mechanisms and clinical management (PJ Barnes, IW Rodger, NC Thomson, Eds.) Academic Press. London. 359-389.
4. Bartels H. (1982). Open junctions in the venular plexuses of the bronchial microcirculation. J Submicrosc Cytol 14: 93-97.
5. Blosser S, Mitzner W, Wagner EM. (1994). Effects of increased bronchial blood flow on airway morphometry, resistance, and reactivity. J Appl Physiol 76: 1624-1629.
6. Butler J. (Ed.). (1992). The bronchial circulation. p. 1-806. Marcel Dekker. New York. 1-806.
7. Cabanes LR, Wber SN, Matran R, Regnard J, Richard MO, DeGeorges ME, Lockhart A. (1989). Bronchial hyperresponsiveness to methacholine in patients with impaired left ventricular function. N Engl J Med 320: 1317-1322.
8. Coleridge HM, Coleridge JCG, Green JF, Parsons GH. (1992). Pulmonary C-fiber stimulation by capsaicin evokes reflex cholinergic bronchial vasodilation in sheep. J Appl Physiol 72: 770-778.
9. Corfield DR, Hanafi Z, Webber SE, Widdicombe JG. (1990). Structural studies of the tracheal vasculature in several species including man. Eur Respir J 3: 675.
10. Corfield DR, Hanafi Z, Webber SE, Widdicombe JG. (1991). Changes in mucosal thickness and blood flow in sheep. J Appl Physiol 71: 1282-1288.
11. Corfield DR, Webber SE, Widdicombe JG. (1993). Distribution of blood flow in the perfused tracheae of sheep: a search for arteriovenous anastomoses. J Appl Physiol 74: 1856-1861.
12. Corboz MR, Ballard ST, Boyette ST, Taylor AE. (1995). Distribution of functional adrenergic receptor subtypes in the microcirculation of rat trachea. Am J Respir Crit Care Med 151: 1589-1596.
13. Corboz MR, Ballard ST, Taylor AE. (1996). β-adrenergic stimulation of the tracheal microvasculature in anesthetized rats. Am J Respir Crit Care Med (in press)
14. Deffebach ME, Charan NB, Lakshminarayan S, Butler J. (1987). The bronchial circulation: small but vital attribute of the lung. Am Rev Respir Dis 135: 463-481.
15. Deffebach ME, Salonen RO, Webber SE, Widdicombe JG. (1989). Cold and hyperosmolar fluids in canine trachea: vascular and smooth muscle tone and albumin flux. J Appl Physiol 66: 1309-1315.
16. Dinh Xuan AT, Chaussain M, Regnard J, Lockhart A. (1989). Pretreatment with an inhaled alpha 1 adrenergic agonist, methoxamine, reduces exercise induced asthma. Eur Respir J 2: 409-414.
17. Erjefalt IAL, G-Wagner Z, Strand SE, Persson CGA. (1985). A method for studies of tracheobronchial microvascular permeability to macromolecules. J Pharmacol Med 14: 275-283.
18. Erjefalt I, Persson CGA. (1989). Inflammatory passage of plasma macromolecules into airway wall and lumen. Pulm Pharmacol 2: 93-102.
19. Erjefalt I, Persson CGA. (1990). On the use of absorbing discs to sample mucosal surface liquids. Clin Exp Allergy 20: 193-197.
20. Erjefalt I, Persson CGA. (1991). Pharmacologic control of plasma exudation into tracheobronchial airways. Am Rev Respir Dis 143: 1008-1014.
21. Fishman AP. (1980). Pulmonary diseases and disorders. McGraw-Hill. New York. 400.
22. Freed AN, Omori C, Hubbard WC, Adkinson NF Jr. (1994). Dry air- and hypertonic aerosol-induced bronchoconstriction and cellular responses in the canine lung periphery. Eur Respir J 7: 1308-1316.
23. Garland A, Ray DW, Doerschuk CM, Alger L, Eappon S, Hernandez C, Jackson M, Solway J. (1991). Role of tachykinins in hyperpnea-induced bronchovascular hyperpermeability in guinea pigs. J Appl Physiol 70: 27-35.
24. Gilbert IA, Winslow CJ, Lenner KA. (1993). Vascular volume expansion and thermally induced asthma. Eur Respir J 6: 189-197.
25. Hayek Von H. (1960). The human lung. Hafner Publishing Co Inc. New York.
26. Hill P, Goulding D, Webber SE, Widdicombe JG. (1989). Blood sinuses in the submucosa of the large airways of the sheep. J Anat 162: 235-247.
27. Hirabayashi M, Yamamoto T. (1984). An electron-microscopic study of the endothelium in mammalian bronchial microvasculature. Cell Tissue Res 236: 19-25.
28. Hughes T. (1965). Microcirculation of the tracheobronchial tree. Nature (London) 206: 425-426.
29. Kowalski ML, Didier A, Kaliner MA. (1989). Neurogenic inflammation in the airways. Am Rev Respir Dis 140: 101-109.
30. Lametschwandtner A, Staindl O, Lametschwandtner-Albrecht U, Grunt T. (1983). Die Vaskularisation der zervikalen trachea und ihre kilnische Relevanz. Eine rasterelekronenmikroskopische untersuchung an Korrosionpraparaten. Hals-Nasen-Ohrenheilk 31: 387-394.
31. Laitinen A, Laitinen LA. (1990). Vascular beds in the airways of normal subjects and athmatics. Eur Respir J 12: 659-662.
32. Laitinen A, Laitinen LA, Moss R, Widdicombe JG. (1989). Organisation and structure of the tracheal and bronchial blood vessels in the dog. J Anat 165: 133-140.
33. Laitinen L. (1986). Detailed analysis of the neural elements in human airways. In: Neural regulation of the airways in health and disease (M Kaliner, PJ Barnes, Eds.) Marcel Dekker. New York. 35-36.
34. Laitinen LA, Laitinen A. (1991). Overview of the pathology of asthma. In: Pharmacology of Asthma, Handbook of Experimental Pharmacology (CP Page, PJ Barnes, Eds.) Springer-Verlag. New York. 1-25.
35. Laitinen LA, Laitinen A. (1992). The bronchial circulation. Histology and electron microscopy. In: The bronchial circulation (J Butler, Ed.) Marcel Dekker. New York. 79-98.
36. Laitinen LA, Robinson NP, Laitinen A, Widdicombe JG. (1986). Relationship between tracheal mucosal thickness and vascular resistance in dogs. J Appl Physiol 61: 2186-2194.
37. Mariassy AT, Gazeroglu H, Wanner A. (1991). Morphometry of the subepithelial circulation in the sheep airways: Effect of vascular congestion. Am Rev Respir Dis 163: 162-166.
38. Matran R. (1991). Neural control of lower airway vasculature. Acta Physiol Scand 142: 1-54.
39. Matthay MA. (1992). The bronchial and systemic circulations in lung and pleural fluid and protein balance. In: The bronchial circulation (J Butler, Ed.) Marcel Dekker. New York. 389-415.
40. McDonald DM. (1990). The ultrastructure and permeability of tracheobronchial blood vessels in health and disease. Eur Respir J (Suppl 12): 572S-585S.
41. McDonald DM. (1994). The concept of neurogenic inflammation in the respiratory tract. In: Neuropeptides in respiratory medicine (MA Kaliner, PJ Barnes, GHH Kunkel, JN Baraniuk, Eds.). Marcel Dekker. New York. 321-349.
42. McDonald DM. (1994). Endothelial gaps and permeability of venules in rat tracheas exposed to inflammatory stimuli. Am J Physiol 266: 61-83.
43. McFadden ERJ. (1990). Hypothesis: exercise-induced asthma as a vascular phenomenon. Lancet 880-883.
44. Michel CC. (1992). Albumin transfer in capillaries. Am Rev Respir Dis 146: 532-536.
45. Miodonski A, Kus T, Tyrankiawicz R. (1980). Scanning electron microscopical study of tracheal vascularization in guinea pig. Arch Otolarygol 106: 31-37.
46. Mitzer W, Wagner E, Brown RH. (1995). Is asthma a vascular disorder? Chest 107: 97-104.
47. Omori C, Schofield BH, Mitzner W, Freed AN. (1995). Hyperpnea with dry air causes time-dependent alterations in mucosal morphology and bronchovascular permeability. J Appl Physiol 78: 1043-1051.
48. Persson CG. (1987). Leakage of macromolecules from the tracheobronchial microcirculation. Am Rev Respir Dis 135: S71-S75.
49. Persson CG. (1992). Plasma exudation from tracheobronchial microvessels in health and disease. In: The bronchial circulation (J Butler, Ed.) Marcel Dekker. New York. 443-473.
50. Prazma J, Coleman CC, Shockley WW, Boucher RC. (1994). Tracheal vascular response to hypertonic and hypotonie solutions. J Appl Physiol 76: 2275-2280.
51. Price AM, Webber SE, Widdicombe JG. (1990). Transport of albumin by the rabbit trachea in vitro. J Appl Physiol 68: 726-730.
52. Renkin E. (1992). Cellular and intercellular transport pathways in exchange vessel. Am Rev Respir Dis 146: 528-531.
53. Reynolds AM, Zadow SP, Scicchitano R, McEvoy RD. (1992). Airway hypocapnia increases microvascular leakage in the guinea pig trachea. Am Rev Respir Dis 145: 80-84.
54. Sahin G, Webber SE, Widdicombe JG. (1987). Lung and cardiac reflex actions on the tracheal vasculature in anaesthetized dogs. J Physiol 387: 47-57.
55. Salonen RO, Webber SE, Deffebach ME, Widdicombe JG. (1991). Tracheal vascular and smooth muscle responses to air temperature and humidity in dogs. J Appl Physiol 71: 50-59.
56. Schoefl GI. (1964). Electron microscopic observations in the regeneration of blood vessels after injury. Ann NY Acad Sci 116: 789-802.
57. Sobin SS, Frasher WG, Tremer HM, Hadley GG. (1963). The microcirculation of the tracheal mucosa. Angiology 14: 165-170.
58. Solway J. (1992). Respiratory air conditioning and the bronchial circulation. In: The bronchial circulation (J Butler, Ed.) Marcel Dekker, Inc. New York. 291-336.
59. Solway J, Leff AR, Dreshaj I, Munoz NM, Ingenito EP, Michaels D, Jr., Ingram RH, Drazen JM. (1986). Circulatory heat sources for canine respiratory heat exchange. J Clin Invest 78: 1015-1019.
60. Strek P, Nowogrodzka-Zagorska M, Litwin JA, Miodonski AJ. (1994). The lung in closeview: a corrosion casting study on the vascular system of human foetal trachea. Eur Respir J 7: 1669-1672.
61. Wagner EM. (1992). Mechanical aspects of physiological regulation of the bronchial circulation. In: The bronchial circulation (J Butler, Ed.). Marcel Dekker. New York. 219-248.
62. Wanner A. (1989). Circulation of the airway mucosa. J Appl Physiol 67: 917-925.
63. Widdicombe JG. (1995). Microvascular anatomy of the airways. p. 722-732. In: Asthma and Rhinitis (WW Busse, ST Holgate, Eds.) Blackwell Scientific Publications. Boston.
64. Widdicombe JG. (1993). Why are the airways so vascular? Thorax 48: 290-295.
65. Widdicombe JG, Webber SE. (1992). Neuroregulation and pharmacology of the tracheobronchial circulation. In: The bronchial circulation (J Butler, Ed.) Marcel Dekker. New York. 249-289.
66. Widdicombe JH, Widdicombe JG. (1995). Regulation of human airway surface liquid. Resp Physiol 99: 3-12.
67. Yager D, Kamm RD, Drazen JM. (1995). Airway wall liquid. Sources and role as an amplifier of bronchoconstriction. Chest 107: 105-110.
68. Yoshihara S, Chan B, Yamawaki I, Geppetti P, Ricciardolo FLM, Massion PP, Nadel JA. (1995). Plasma extravasation in the rat trachea induced by cold air is mediated by tachykinin release from sensory nerves. Am J Respir Crit Care Med 1011-1017.