Cytochromes P450 2B1 and P450 2B2 demethylate N-nitrosodimethylamine and N-nitrosomethylaniline in vitro

General Physiology and Biophysics

Volumn 15, Issue 3, 1996, Pages 211-223

  Stiborova M ^a   Hansikova H ^a   Frei, E ^b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Catalysis; Cytochrome P450 isoenzymes; Demethylation; N Nitrosamines

Indexed keywords

1,2 DILAUROYLPHOSPHATIDYLCHOLINE; 1,2-DILAUROYLPHOSPHATIDYLCHOLINE; CYTOCHROME P450; CYTOCHROME P450 2B1; DIMETHYLNITROSAMINE; N METHYL N NITROSOANILINE; N-METHYL-N-NITROSOANILINE; NITROSAMINE; PHENOBARBITAL; PHOSPHATIDYLCHOLINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; STEROID 16 BETA HYDROXYLASE; STEROID 16-BETA-HYDROXYLASE; STEROID MONOOXYGENASE; UNSPECIFIC MONOOXYGENASE;

ANIMAL; ARTICLE; ENZYME SPECIFICITY; ENZYMOLOGY; ISOLATION AND PURIFICATION; KINETICS; LIVER MICROSOME; METABOLISM; RAT; SPECTROPHOTOMETRY;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 ENZYME SYSTEM; DIMETHYLNITROSAMINE; KINETICS; MICROSOMES, LIVER; NADPH-FERRIHEMOPROTEIN REDUCTASE; NITROSAMINES; PHENOBARBITAL; PHOSPHATIDYLCHOLINES; RATS; SPECTROPHOTOMETRY; STEROID HYDROXYLASES; SUBSTRATE SPECIFICITY;

EID: 0030155090     PISSN: 02315882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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