A possible common cell surface autoantigen in islet β-cells and thyroid follicular cells in patients with non-insulin dependent diabetes mellitus and chronic thyroiditis

Endocrine Journal

Volumn 43, Issue 3, 1996, Pages 299-306

  Igawa, Takahiko ^a   Nakabayashi, Hajime ^a   Takeda, Ryoyu ^a   Kurata, Yoriaki ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Autoimmune polyglandular endocrinopathy; Islet cell surface antibodies (ICSA); Organ specific autoantigen

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; PANCREAS ISLET CELL ANTIBODY;

ADENOCARCINOMA; ADOLESCENT; ADULT; AGED; ANTIBODY SPECIFICITY; ARTICLE; AUTOIMMUNE THYROIDITIS; AUTORADIOGRAPHY; CELL CULTURE; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; IMMUNOLOGY; MALE; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PATHOPHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; THYROID TUMOR;

ADENOCARCINOMA, PAPILLARY; ADOLESCENT; ADULT; AGED; AUTOANTIBODIES; AUTOANTIGENS; AUTORADIOGRAPHY; DIABETES MELLITUS, TYPE 2; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; ISLETS OF LANGERHANS; MALE; MIDDLE AGED; ORGAN SPECIFICITY; THYROID NEOPLASMS; THYROIDITIS, AUTOIMMUNE; TUMOR CELLS, CULTURED;

EID: 0030155004     PISSN: 09188959     EISSN: None     Source Type: Journal    
DOI: 10.1507/endocrj.43.299     Document Type: Article

References (39)

1. Bottazzo GF, Florin-Christensen A, Doniach D (1974) Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. Lancet 2: 1279-1283.
2. Bottazzo GF, Dean BM, Gorsuch AN, Cudworth AG, Doniach D (1980) Complement-fixing islet-cell antibodies in type-I diabetes: Possible monitors of active beta-cell damage. Lancet 1: 668-672.
3. Maclaren NK, Huang SW, Fogh J (1975) Antibody to cultured human insulinoma cells in insulin-dependent diabetes. Lancet 1: 997-999.
4. Lernmark Å, Freedman ZR, Hofmann C, Rubenstein AH, Steiner DF, Jackson RL, Winter RJ, Traisman HS (1978) Islet-cell-surface antibodies in juvenile diabetes mellitus. N Engl J Med 299: 375-380.
5. Weetman AP, McGregor AM (1984) Autoimmune thyroid disease: Development in our understanding. Endocr Rev 5: 309-355.
6. Drell DW, Notkins AL (1987) Multiple immunological abnormalities in patients with Type 1 (insulin-dependent) diabetes mellitus. Diabetologia 30: 132-143.
7. Carpenter CCJ, Solomon N, Silverberg SG, Bledsoe T, Northcutt RC, Klinenberg JR, Bennett IL, Harvey AM (1964) Schmidt's syndrome (Thyroid and adrenal insufficiency): A review of the literature and a report of fifteen new cases including ten instances of coexistent diabetes mellitus. Medicine (Oxford) 43: 153-180.
8. Oka N, Notsu K, Note S, Nabeya N, Kuno S, Sakurami T (1987) Significance of anti-islet cell antibodies in patients with diabetes mellitus and autoimmune thyroid disorders. J Jpn Soc Intern Med 76: 802-809 (In Japanese).
9. Van De Winkel M, Smets G, Gepts W, Pipeleers D (1982) Islet cell surface antibodies from insulin-dependent diabetics bind specifically to pancreatic B cells. J Clin Invest 70: 41-49.
10. Suzuki M, Kawazu S, Negishi K, Watanabe T, Hokama A, Takahashi H, Shunto S, Moritani S, Inoue I, Takei S, Ishii J (1988) Clinical implications of islet cell surface antibodies (ICSA) in non-insulin dependent diabetes mellitus - In relation to pancreatic B cell function and HLA antigens. J Jpn Diab Soc 31: 801-808 (In Japanese with English abstract).
11. Lernmark Å, Sehlin J, Täljedal IB, Kromann H, Nerup J (1978) Possible toxic effects of normal and diabetic patient serum on pancreatic B-cells. Diabetologia 14: 25-31.
12. World Health Organization (1980) WHO Expert Committee on Diabetes Mellitus, Second Report, Geneva, World Health Organization, Technical Report Series 646: 1-80.
13. Uchida S, Watanabe S, Aizawa T, Kato K, Furuno A, Muto T (1976) Induction of papillary ependymomas and insulinomas in the Syrian golden hamster by BK virus, a human papovavirus. Gann 67: 857-865.
14. Satoh N, Kurata Y (1988) Monoclonal antibodies against human thyroid cancer. In: Scientific Report Committee (ed) Cancer Research Institute Report (1985-1987). Kanazawa, Japan, 57.
15. Rabin BS, Nakamura RM (1980) Improved method for detection of anti-tissue antibody by indirect immunofluorescence using fixed tissue. J Clin Lab Immunol 4: 119-124.
16. Schwartz BD, Nathenson SG (1971) Isolation of H-2 alloantigens solubilized by the detergent NP-40. J Immunol 107: 1363-1367.
17. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193: 265-275.
18. 131I- labeled human growth hormone of high specific radioactivity. Biochem J 89: 114-123.
19. Kessler SW (1975) Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: Parameters of the interaction of antibody-antigen complexes with protein A. A J Immunol 115: 1617-1624.
20. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
21. Kurata Y (1967) Immunopathology in autoimmune thyroiditis: Refining of organ-specific antigens. Tr Soc Path Jap 56: 374-378.
22. Colman PG, Campbell IL, Kay TWH, Harrison LC (1987) 64,000-Mr autoantigen in Type I diabetes. Evidence against its surface location on human islet. Diabetes 36: 1432-1440.
23. Dobersen MJ, Scharff JE, Ginsberg-Fellner F, Notkins AL (1980) Cytotoxic autoantibodies to beta cells in the serum of patients with insulin-dependent diabetes mellitus. N Engl J Med 303: 1493-1498.
24. Kobayashi T, Itoh T, Kosaka K, Sato K, Tsuji K (1987) Time course of islet cell antibodies and β-cell function in non-insulin-dependent stage of type I diabetes. Diabetes 36: 510-517.
25. Nakabayashi H, Kawato M, Ueda M (1974) Clinical features of chronic thyroiditis. J Jpn Soc Intern Med 63: 1107-1108 (In Japanese).
26. Bastenie PA, Bonnyns M, Vanhaelst L, Nève P (1972) Diseases associated with autoimmune thyroiditis. In: Bastenie PA, Ermans AM (eds) Thyroiditis and Thyroid Function - Clinical, Morphological and Physiopathological Studies. Pergamon Press, Oxford, New York, 1st ed, 261-274.
27. Negishi K (1983) Islet cell surface antibodies(ICSA) radioimmunoassay with insulinoma cell and it's clinical application. J Jpn Diab Soc 26: 485-496 (In Japanese with English abstract).
28. Baekkeskov S, Nielsen JH, Marner B, Bilde T, Ludvigsson J, Lernmark Å (1982) Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins. Nature 298: 167-169.
29. Baekkeskov S, Christie M (1989) Characterization of the 64-kD membrane autoantigen in pancreatic β cells. In: Hanahan D, McDevitt HO, Cahill, Jr. GF (eds) Current Communications in Molecular Biology. Cold Spring Harbor Laboratory, New York, 181-186.
30. Savilahti E, Akerblom HK, Koskimies S (1988) Children with newly diagnosed insulin-dependent diabetes mellitus have increased levels of cows' milk antibodies. Diabetes Res 7: 137-140.
31. Atkinson MA, Maclaren NK, Scharp DW, Lacy PE, Riley WJ (1990) 64,000 Mr autoantibodies as predictors of insulin-dependent diabetes. Lancet 335: 1357-1360.
32. Betterle C, Presotto F, Pedini B, Moro L, Slack RS, Zanette F, Zanchetta R (1987) Islet cell and insulin autoantibodies in organ-specific autoimmune patients. Their behaviour and predictive value for the development of Type 1 (insulin-dependent) diabetes mellitus. A 10-year follow-up study. Diabetologia 30: 292-297.
33. Baekkeskov S, Jan Aanstoot H, Christgau S, Reetz A, Solimena M, Cascalho M, Folli F, Richter-Olesen H, De Camilli P (1990) Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase. Nature 347: 151-156.
34. Erlander MG, Tillakaratne NJK, Feldblum S, Patel N, Tobin AJ (1991) Two genes encode distinct glutamate decarboxylases with different responses to pyridoxal phosphate. Neuron 7: 91-100.
35. Atkinson MA, Kaufman DL, Newman D, Tobin AJ, Maclaren NK (1993) Islet cell cytoplasmic autoantibody reactivity to glutamate decarboxylase in insulin-dependent diabetes. J Clin Invest 91: 350-356.
36. Petersen JS, Russel S, Marshall MO, Kofod H, Buschard K, Cambon N, Karlsen AE, Boel E, Hagopian WA, Hejnes KR, Moody A, Dyrberg T, Lernmark Å, Madsen OD, Michelsen BK (1993) Differential expression of glutamic acid decarboxylase in rat and human islets. Diabetes 42: 484-495.
37. Erdö SL, Wolff JR (1990) γ-Aminobutyric acid outside the mammalian brain. J Neurochem 54: 363-372.
38. Salvi M, Miller A, Wall JR (1988) Human orbital tissue and thyroid membranes express a 64 kDa protein which is recognized by autoantibodies in the serum of patients with thyroid-associated ophthalmopathy. FEBS Letters 232: 135-139.
39. Saivi M, Fukazawa H, Bernard N, Hiromatsu Y, How J, Wall JR (1988) Role of autoantibodies in the pathogenesis and association of endocrine autoimmune disorders. Endocrine Rev 9: 450-466.