An assessment of docosahexaenoic acid (DHA) intake with special reference to lipid metabolism in rats

Journal of Nutritional Science and Vitaminology

Volumn 42, Issue 3, 1996, Pages 195-207

  Saito, Morio ^a   Kubo, Kazuhiro ^a,b   Ikegami, Sachie ^a  

^a NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^b TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

Author keywords

Assessment of docosahexaenoic acid intake; Docosahexaenoic acid; Docosahexaenoic acid intake; Fatty acid profile; Lipid peroxidation; Rat; Serum lipid; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; CHOLESTEROL; DOCOSAHEXAENOIC ACID; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; PHOSPHOLIPID; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL;

ANIMAL; ARTICLE; BLOOD; CHEMOLUMINESCENCE; DIET; KIDNEY; LIPID PEROXIDATION; LIVER; MALE; METABOLISM; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIOXIDANTS; CHEMILUMINESCENT MEASUREMENTS; CHOLESTEROL; CHOLESTEROL, HDL; DIET; DOCOSAHEXAENOIC ACIDS; KIDNEY; LIPID PEROXIDATION; LIPIDS; LIVER; MALE; PHOSPHOLIPIDS; RATS; RATS, SPRAGUE-DAWLEY; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TRIGLYCERIDES; VITAMIN E;

EID: 0030154911     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.42.195     Document Type: Article

References (37)

1. Herold, P. M., and Kinsella, J. E. (1986): Fish oil consumption and decreased risk of cardiovascular disease: a comparison of findings from animal and human feeding trials. Am. J. Clin. Nutr., 43, 566-598.
2. Simopoulos, A. P. (1991): Omega-3 fatty acids in health and disease and in growth and development. Am. J. Clin. Nutr., 54, 438-463.
3. Neuringer, M., Anderson, G. J., and Connor, W. E. (1988): The essentiality of n-3 fatty acids for the development and function of the retina and brain. Ann. Rev. Nutr., 8, 517-541.
4. Nordoy, A. (1991): Is there a rational use for n-3 fatty acids (fish oils) in clinical medicine. Drugs, 42, 331-342.
5. Chee, K. M., Gong, J. X., Good-Rees, D. M., Meydani, M., Ausman, L., Johnson, J., Siguel, E. N., and Schaefer, E. J. (1990): Fatty acid content of marine oil capsules. Lipids, 25, 523-528.
6. Hammer, C. T., and Wills, E. D. (1978): The role of lipid components of the diet in the regulation of the fatty acid composition of the rat liver endoplasmic reticulum and lipid peroxidation. Biochem. J., 174, 585-593.
7. Mouri, K., Ikesu, H., Esaka, T., and Igarashi, O. (1984): The influence of marine oil intake upon levels of lipids, alpha-tocopherol and lipid peroxidation in serum and liver of rats. J. Nutr. Sci. Vitaminol., 30, 307-318.
8. Nalbone, G., Leonardi, J., Termine, E., Portugal, H., Lechene, P., Pauli, A.-M., and Lafont, H. (1989): Effects of fish oil, corn oil and lard diets on lipid peroxidation status and glutathione peroxidase activities in rat heart. Lipids, 24, 179-186.
9. Hu, M.-L., Frankel, E. N., Leibovitz, B. E., and Tappel, A. L. (1989): Effect of dietary lipids and vitamin E on in vitro lipid peroxidation in rat liver and kidney homogenates. J. Nutr., 119, 1574-1582.
10. Saito, M., and Nakatsugawa, K. (1994): Increased susceptibility of liver to lipid peroxidation after ingestion of a high fish oil diet. Int. J. Vit. Nutr. Res., 64, 144-151.
11. Meydani, M., Natiello, F., Goldin, B., Free, N., Woods, M., Schaefer, E., Blumberg, J. B., and Gorbachi, S. L. (1991): Effect of long-term fish oil supplementation on vitamin E status and lipid peroxidation in women. J. Nutr., 121, 484-491.
12. American Institute of Nutrition (1980): Second report of the Ad Hoc Committee on standards for nutritional studies. J. Nutr., 110, 1726.
13. Saito, M., Nakatsugawa, K., Oh-hashi, A., Nishimuta, M., and Kodama, N. (1992): Comparison of vitamin E levels in human plasma, red blood cells and platelets following varying intakes of vitamin E. J. Clin. Biochem. Nutr., 12, 59-68.
14. Mino, M., Tamai, H., Yasuda, C., Igarashi, O., Hayashi, M., Hirahara, F., Katsui, G., and Kijima, S. (1988): Biopotencies of tocopherol analogues as determined by dialuric acid induced hemolysis in rats. Vitamins (Japan), 62, 241-246.
15. Pietrangelo, A., Grandi, R., Tripodi, A., Tomasi, A., Ceccarelli, D., Ventura, E., and Msini, A. (1990): Lipid composition and fluidity of liver mitochondria, microsomes and plasma membrane of rats with chronic dietary iron overload. Biochem. Pharmacol., 39, 123-128.
16. Cosgrove, J. P., Church, D. F., and Pryor, W. A. (1987): The kinetics of the autoxidation of polyunsaturated fatty acids. Lipids, 22, 299-304.
17. Yagi, K. (1976): A simple fluorometric assay for lipoperoxide in blood plasma. Biochem. Med., 15, 212-216.
18. Tsuchida, M., Miura, T., Mizutani, K., and Aibara, K. (1985): Fluorescent substances in mouse and human sera as parameter of in vivo lipid peroxidation. Biochim. Biophys. Acta, 834, 196-204.
19. Ohkawa, H., Ohishi, N., and Yagi, K. (1979): Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem., 95, 351-358.
20. Miyazawa, T., Tsuchiya, K., and Kaneda, T. (1984): Riboflavin tetrabutyrate: an antioxidative synergist of alfa-tocopherol as estimated by hepatic chemiluminescence. Nutr. Rep. Int., 29, 157-165.
21. Saito, M., and Yamaguchi, M. (1988): Influence of excessive ascorbic acid dose on liver microsomal mixed function oxidase system in guinea pigs. J. Clin. Biochem. Nutr., 4, 123-137.
22. Flethcher, B. L., Dillard, C. J., and Tappel, A. L. (1973): Measurement of fluorescent lipid peroxidation products in biological systems and tissues. Anal. Biochem., 52, 1-9.
23. Saito, M., Oh-hashi, A., Kubota, M., Nishide, E., and Yamaguchi, M. (1990): Mixed function oxidases in response to different types of dietary lipids in rats. Br. J. Nutr., 63, 249-257.
24. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951): Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265-275.
25. Folch, J., Lees, M., and Sloane-Stanley, G. H. (1957): A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem., 193, 265-275.
26. Duncan, D. B. (1957): Multiple range tests for correlated and heteroscedastic means. Biometrics, 13, 164-176.
27. Kobatake, Y., Kuroda, K., Jinnouchi, H., Nishide, E., and Innami, S. (1984): Differential effects of dietary eicosapentaenoic and docosahexaenoic fatty acids on lowering of triglyceride and cholesterol levels in the serum of rats on hypercholesterolemic diet. J. Nutr. Sci. Vitaminol., 30, 357-372.
28. Ikeda, I., Wakamatsu, K., Inayoshi, A., Imaizumi, K., Sugano, M., and Yazawa, K. (1994): α-Linolenic, eicosapentaenoic and docosahexaenoic acids affect lipid metabolism differently in rats. J. Nutr., 124, 1898-1906.
29. Saito, M. (1994): Effect of dietary alpha-linolenic, eicosapentaenoic and docosahexaenoic acids on liver microsomal mixed-function oxidases in rats. Ann. Nutr. Metab., 38, 313-321.
30. Bidlack, W. R., Brown, R. C., and Mohan, C. (1986): Nutritional parameters that alter hepatic drug metabolism, conjugation, and toxicity. Fed. Proc., 45, 142-148.
31. Porter, T. D., and Coon, M. J. (1991): Cytochrome P-450: multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms. J. Biol. Chem., 266, 13469-13472.
32. Croset, M., and Kinsella, J. E. (1989): Changes in phospholipid fatty acid composition of mouse cardiac organelles after feeding graded amounts of docosahexaenoate in presence of high levels of linoleate. Effect on cardiac ATPase activities. Ann. Nutr. Metab., 33, 125-142.
33. Taniguchi, H., Suzuki, K., Takita, T., Chung, S. Y., Hayakawa, T., Nakamura, K., and Innami, S. (1993): Comparative effects of eicosapentaenoic acid and docosahexaenoic acid on n-6 and n-3 fatty acid profiles of phospholipid classess in several tissues of rats fed a hypertriglyceridemic diet. J. Clin. Biochem. Nutr., 14, 151-162.
34. Yamaoka, S., Urade, R., and Kito, M. (1988): Mitochondrial function in rats is affected by modification of membrane phospholipids with dietary sardine oil. J. Nutr., 118, 290-296.
35. Yoshida, A. (1991): Appropriate amounts of fat intake. J. Jpn. Oil Chemists' Soc., 40, 467-472.
36. Holman, R. T., Johnson, S. B., and Hatch, T. F. (1982): A case of human linolenic acid deficiency involving neurological abnormalities. Am. J. Clin. Nutr., 35, 617-623.
37. Bjerve, K. S., Mostad, I. L., and Thoresen, L. (1987): Alpha-linolenic acid deficiency in patients on long-term gastric-tube feeding: estimation of linolenic acid and long-chain unsaturated n-3 fatty acid requirement in man. Am. J. Clin. Nutr., 45, 66-77.