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Volumn 56, Issue 5, 1996, Pages 313-318

p16INK4/p15INK4B gene inactivation is a frequent event in malignant T-cell lines

Author keywords

p16INK4 p15INK4B; T cell lines; Tumor suppressor genes

Indexed keywords

CARRIER PROTEIN; CDKN2B PROTEIN, HUMAN; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2B; PRIMER DNA; PROTEIN P16INK4A; TUMOR SUPPRESSOR PROTEIN;

EID: 0030140216     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0609.1996.tb00721.x     Document Type: Article
Times cited : (9)

References (35)
  • 1
    • 0026721505 scopus 로고
    • Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes
    • KORSMEYER S. Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes. Annu Rev Immun 1992: 10: 785-807.
    • (1992) Annu Rev Immun , vol.10 , pp. 785-807
    • Korsmeyer, S.1
  • 2
    • 0026012461 scopus 로고
    • Infrequent mutation in the p53 gene in primary human T-cell acute lymphoblastic leukemia
    • JONVEAUX P, BERGER R. Infrequent mutation in the p53 gene in primary human T-cell acute lymphoblastic leukemia. Leukemia 1991: 5: 839-840.
    • (1991) Leukemia , vol.5 , pp. 839-840
    • Jonveaux, P.1    Berger, R.2
  • 3
    • 0027361941 scopus 로고
    • Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood
    • WADA M, BARTRAM C, NAKAMURA H, et al. Analysis of p53 mutations in a large series of lymphoid hematologic malignancies of childhood. Blood 1993: 82: 3163-3169.
    • (1993) Blood , vol.82 , pp. 3163-3169
    • Wada, M.1    Bartram, C.2    Nakamura, H.3
  • 4
    • 0025201977 scopus 로고
    • Deletion of human retinoblastoma gene in primary leukemias
    • CHEN Y-C, CHEN P-J, YEH S-H, et al. Deletion of human retinoblastoma gene in primary leukemias. Blood 1990: 10: 2060-2064.
    • (1990) Blood , vol.10 , pp. 2060-2064
    • Chen, Y.-C.1    Chen, P.-J.2    Yeh, S.-H.3
  • 5
    • 0027074442 scopus 로고
    • Why don't germline mutations in RB1 predispose to leukemia?
    • PHILLIPS R, GILL R, ZACKSENHAUS E, et al. Why don't germline mutations in RB1 predispose to leukemia? Curr Top Microbiol Immun 1992: 182: 485-491.
    • (1992) Curr Top Microbiol Immun , vol.182 , pp. 485-491
    • Phillips, R.1    Gill, R.2    Zacksenhaus, E.3
  • 7
    • 0021799508 scopus 로고
    • Lymphoblastic leukemia with lymphomatous features associated with abnormalities of the short arm of chromosome 9
    • CHILCOTE R, BROWN W, ROWLEY J. Lymphoblastic leukemia with lymphomatous features associated with abnormalities of the short arm of chromosome 9. New Engl J Med 1985: 313: 286-291.
    • (1985) New Engl J Med , vol.313 , pp. 286-291
    • Chilcote, R.1    Brown, W.2    Rowley, J.3
  • 8
    • 0023637789 scopus 로고
    • Abnormalities of the short arm of chromosome 9 with partial loss of material in hematological disorders
    • Pollak C, Hagemeijer A. Abnormalities of the short arm of chromosome 9 with partial loss of material in hematological disorders. Leukemia 1987: 1: 541-548.
    • (1987) Leukemia , vol.1 , pp. 541-548
    • Pollak, C.1    Hagemeijer, A.2
  • 9
    • 0001122795 scopus 로고
    • Homozygous deletion of the α- and β1-interferon genes in human leukemia and derived cell lines
    • DIAZ M, ZIEMIN S, LEBEAU M, et al. Homozygous deletion of the α- and β1-interferon genes in human leukemia and derived cell lines. Proc Natl Acad Sci USA 1988: 85: 5259-5263.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 5259-5263
    • Diaz, M.1    Ziemin, S.2    Lebeau, M.3
  • 10
    • 0025023615 scopus 로고
    • Deletions of interferon genes in acute lymphoblastic leukemia
    • DIAZ M, RUBIN C, HARDEN A, et al. Deletions of interferon genes in acute lymphoblastic leukemia. New Engl J Med 1990: 322: 77-82.
    • (1990) New Engl J Med , vol.322 , pp. 77-82
    • Diaz, M.1    Rubin, C.2    Harden, A.3
  • 11
    • 0025604193 scopus 로고
    • Deletion of α-, - β and ω-IFN genes in malignant cells from children with acute lymphocytic leukemia
    • EINHORN S, GRANDER D, BJÖRK O, et al. Deletion of α-, - β and ω-IFN genes in malignant cells from children with acute lymphocytic leukemia. Cancer Res 1990: 50: 7781-7785.
    • (1990) Cancer Res , vol.50 , pp. 7781-7785
    • Einhorn, S.1    Grander, D.2    Björk, O.3
  • 12
    • 0026770058 scopus 로고
    • Genetic and physical map of the interferon region on chromosome 9p
    • FOUNTAIN J, KAAAYIORGOU M, TARUSCIO D, et al. Genetic and physical map of the interferon region on chromosome 9p. Genomics 1992: 14: 105-112.
    • (1992) Genomics , vol.14 , pp. 105-112
    • Fountain, J.1    Kaaayiorgou, M.2    Taruscio, D.3
  • 13
    • 0026464014 scopus 로고
    • Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia
    • OLOPADE O, BOHLANDER S, POMYKALA H, et al. Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. Genomics 1992: 14: 437-443.
    • (1992) Genomics , vol.14 , pp. 437-443
    • Olopade, O.1    Bohlander, S.2    Pomykala, H.3
  • 14
    • 0027769876 scopus 로고
    • A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
    • SERRANO M, HANNON G, BEACH D. A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 1993: 366: 704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.2    Beach, D.3
  • 15
    • 0028121279 scopus 로고
    • A cell cycle regulator potentially involved in genesis of many tumor types
    • KAMB A, GRUIS N, WEAVER-FELDHAUS J, et al. A cell cycle regulator potentially involved in genesis of many tumor types. Science 1994: 263: 436-440.
    • (1994) Science , vol.263 , pp. 436-440
    • Kamb, A.1    Gruis, N.2    Weaver-Feldhaus, J.3
  • 16
    • 0028275733 scopus 로고
    • Deletions of the cyclin dependent kinase-4 inhibitor gene in multiple human cancers
    • NOBORI T, MIURA K, Wu D, et al. Deletions of the cyclin dependent kinase-4 inhibitor gene in multiple human cancers. Nature 1994: 368: 753-756.
    • (1994) Nature , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.3
  • 17
    • 0028168242 scopus 로고
    • INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 1994: 371: 257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.1    Beach, D.2
  • 19
    • 0027943835 scopus 로고
    • Homozygous loss of the cyclin-dependent kinase 4-inhibitor (p16) gene in human leukemias
    • OGAWA S, HIRANO N, SATO N, et al. Homozygous loss of the cyclin-dependent kinase 4-inhibitor (p16) gene in human leukemias. Blood 1994: 84: 2431-2435.
    • (1994) Blood , vol.84 , pp. 2431-2435
    • Ogawa, S.1    Hirano, N.2    Sato, N.3
  • 20
    • 0028985436 scopus 로고
    • P16 gene homozygous deletions in acute lymphoblastic leukemia
    • QUESNEL B, PREUDHOMME C, PHILIPPE N, et al. P16 gene homozygous deletions in acute lymphoblastic leukemia. Blood 1995: 85: 657-663.
    • (1995) Blood , vol.85 , pp. 657-663
    • Quesnel, B.1    Preudhomme, C.2    Philippe, N.3
  • 21
    • 0027938776 scopus 로고
    • INK4B) display frequent homozygous deletions in primary cell from T- but not from B-cell lineage acute lymphoblastic leukemias
    • INK4B) display frequent homozygous deletions in primary cell from T- but not from B-cell lineage acute lymphoblastic leukemias. Blood 1994: 84: 4038-4044.
    • (1994) Blood , vol.84 , pp. 4038-4044
    • Hebert, J.1    Cayuela, J.2    Berkeley, J.3
  • 22
    • 0028988044 scopus 로고
    • INK4b/MTS2 in pediatric acute lymphoblastic leukemia
    • INK4b/MTS2 in pediatric acute lymphoblastic leukemia. Blood 1995: 85: 2321-2330.
    • (1995) Blood , vol.85 , pp. 2321-2330
    • Okuda, T.1    Shurtleff, S.2    Valentine, M.3
  • 23
    • 0028354775 scopus 로고
    • Interferon system defects in malignant T-cells
    • HEYMAN M, GRANDER D, BRONDUM-NIELSEN K, et al. Interferon system defects in malignant T-cells. Leukemia 1994: 8: 425-434.
    • (1994) Leukemia , vol.8 , pp. 425-434
    • Heyman, M.1    Grander, D.2    Brondum-Nielsen, K.3
  • 24
    • 0022506980 scopus 로고
    • A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
    • FRIEND S, BERNARDS R, ROGEL S, et al. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 1986: 323: 643-646.
    • (1986) Nature , vol.323 , pp. 643-646
    • Friend, S.1    Bernards, R.2    Rogel, S.3
  • 25
    • 0011143015 scopus 로고
    • DNA rearrangements in human follicular lymphoma can involve the 5′ or 3′ region of the bcl-2 gene
    • TSUJIMOTO Y, BASHIR M, GIVOL I, et al. DNA rearrangements in human follicular lymphoma can involve the 5′ or 3′ region of the bcl-2 gene. Proc Natl Acad Sci USA 1987: 84: 1329-1331.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 1329-1331
    • Tsujimoto, Y.1    Bashir, M.2    Givol, I.3
  • 26
    • 0027323518 scopus 로고
    • Deletions of the short arm of chromosome 9, including the interferon-α/β genes, in acute lymphocytic leukemia. Studies on loss of heterozygosity, parental origin of deleted genes and prognosis
    • HEYMAN M, GRANDER D, BRONDUM-NIELSEN K, et al. Deletions of the short arm of chromosome 9, including the interferon-α/β genes, in acute lymphocytic leukemia. Studies on loss of heterozygosity, parental origin of deleted genes and prognosis. Intern J Cancer 1993: 54: 748-753.
    • (1993) Intern J Cancer , vol.54 , pp. 748-753
    • Heyman, M.1    Grander, D.2    Brondum-Nielsen, K.3
  • 27
    • 0029134016 scopus 로고
    • Role of the cyclin-dependent kinase inhibitors in the development of cancer
    • HIRAMA T, KOEFFLER H. Role of the cyclin-dependent kinase inhibitors in the development of cancer. Blood 1995: 86: 841-854.
    • (1995) Blood , vol.86 , pp. 841-854
    • Hirama, T.1    Koeffler, H.2
  • 28
    • 0028940722 scopus 로고
    • Cell-cycle regulators and cancer
    • KAMB A. Cell-cycle regulators and cancer. Trends Genet 1995: 11: 136-140.
    • (1995) Trends Genet , vol.11 , pp. 136-140
    • Kamb, A.1
  • 30
    • 0028172926 scopus 로고
    • INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB
    • INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB. Oncogene 1994: 9: 3375-3378.
    • (1994) Oncogene , vol.9 , pp. 3375-3378
    • Otterson, G.1    Kratzke, R.2    Coxon, A.3
  • 31
    • 0027227650 scopus 로고
    • Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene: Evidence for a role of a adjacent locus
    • LIU Y, SZEKELY L, GRANDER D, et al. Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene: evidence for a role of a adjacent locus. Proc Natl Acad Sci, USA 1993: 90: 8697-8701.
    • (1993) Proc Natl Acad Sci, USA , vol.90 , pp. 8697-8701
    • Liu, Y.1    Szekely, L.2    Grander, D.3
  • 32
    • 0028033422 scopus 로고
    • Rates of p16 (MTS1) mutations in primary tumors with 9p loss
    • CAIRNS P, MAO L, MERLO A, et al. Rates of p16 (MTS1) mutations in primary tumors with 9p loss. Science 1994: 265: 415-416.
    • (1994) Science , vol.265 , pp. 415-416
    • Cairns, P.1    Mao, L.2    Merlo, A.3
  • 34
    • 0028911406 scopus 로고
    • Increased p16 levels correlate with pRb alterations in human urothelial cells
    • YEAGER T, STADLER W, BELAIR C, et al. Increased p16 levels correlate with pRb alterations in human urothelial cells. Cancer Res 1995: 55: 493-497.
    • (1995) Cancer Res , vol.55 , pp. 493-497
    • Yeager, T.1    Stadler, W.2    Belair, C.3
  • 35
    • 0028138707 scopus 로고
    • Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck
    • ZHANG S-Y, KLEIN-SZANTO A, SAUTER E, et al. Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck. Cancer Res 1994: 54: 5050-5053.
    • (1994) Cancer Res , vol.54 , pp. 5050-5053
    • Zhang, S.-Y.1    Klein-Szanto, A.2    Sauter, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.