Age-Related Change of Technetium-99m-HMDP Distribution in the Skeleton

Journal of Nuclear Medicine

Volumn 37, Issue 5, 1996, Pages 815-818

  Kigami, Yusuke ^a   Yamamoto, Itsuo ^a   Ohnishi, Hideo ^a   Miura, Hiroaki ^a   Ohnaka, Yasuo ^a   Ota, Toyotsugu ^a   Yuu, Itsuaki ^a   Masuda, Kazutaka ^a   Morita, Rikushi ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Regional skeletal metabolism; Technetium 99m HMDP; Whole body skeletal uptake

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE I TRIMERIC CROSS LINKED PEPTIDE; COLLAGEN TYPE I TRIMERIC CROSS-LINKED PEPTIDE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; MEDRONATE TECHNETIUM TC 99M; PEPTIDE; PEPTIDE FRAGMENT; PROCOLLAGEN; PROCOLLAGEN TYPE I CARBOXY TERMINAL PEPTIDE; TECHNETIUM TC 99M HYDROXYMETHYLENE DIPHOSPHONATE;

AGE; AGING; ARTICLE; BLOOD; BONE; COMPARATIVE STUDY; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; OSTEOPOROSIS; SCINTISCANNING; SEX DIFFERENCE;

AGE FACTORS; AGING; ALKALINE PHOSPHATASE; BONE AND BONES; COLLAGEN; COLLAGEN TYPE I; FEMALE; HUMANS; MALE; MIDDLE AGED; OSTEOPOROSIS; PEPTIDE FRAGMENTS; PEPTIDES; PROCOLLAGEN; SEX FACTORS; TECHNETIUM TC 99M MEDRONATE;

EID: 0030136702     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Fogelman I, Collier BD, Brown ML. Bone scintigraphy: Part 3. Bone scanning in metabolic bone disease. J Nucl Med 1993;34:2247-2252.
2. 18] fluoride ion and PET. J Comput Assist Tomogr 1993;17: 34-41.
3. Heaney RP, Bauer GC, Bronner F. et al. A normal reference standard for radiocalcium turnover and excretion in humans. J Lab Clin Med 1964;64:21-34,
4. Delmas PD. Biochemical markers of bone turnover. I: Theoretical considerations and clinical use in osteoporosis. Am J Med 1993;95:1 ls-16s.
5. 99mTc-labeled pyrophosphate [English Abstract]. Kaku Igaku 1974; 11:637-645.
6. Creutzig H, Dach W. The "Sickle-Sign" in bone scintigraphy. Eur J Med 1981;6: 99-101.
7. 99mTc-labeled pyrophosphate at 24 hr: physiological basis of the method for assessing the metabolism of bone in disease. Calcif Tissue Int 1983;35:37-42.
8. Senda K, Itoh S. Evaluation of diffusely high uptake by the calvaria in bone scintigraphy. Ann Nucl Med 1987;1:23-26.
9. Roos JC, van U, van BM, Oei HY, van RP. The hot skull: malignant or feminine? Eur J Nucl Med 1987;13:207-209.
10. Hale TI. Jucker A. The prognostic value of diffuse skull activity in bone scintigraphy from breast cancer patients [Letter]. Eur J Nucl Med 1987; 13:106-107.
11. 99mTc-MDP bone uptake from a bone scan image: quantitative measurement of radioactivity in global skeletal regions of interest. Nucl Med Commun 1992;13:55-60.
12. Melkko J, Niemi S, Risteli J. Radioimmunoassay of the carboxyterminal propeptide of human type 1 procollagen. Clin Chem 1990;36:1328-1332.
13. Risteli J, Elomaa I, Niemi S, Novamo A, Risteli L. Radioimmunoassay for pyridinoline cross-linked carboxy-terminal telopeptide of type 1 collagen degradation. Clin Chem 1993;39:635-640.
14. Yamamoto I, Takada M, Yuu I, et al. Radioimmunoassay for the pyridinoline cross-linked carboxy-terminal telopeptide of type 1 collagen (1CTP) - some basic aspects of the RIA kit and clinical evaluation in various bone diseases [English Abstract]. Kaku Igaka 1993;30:1411-1417.
15. Yamamoto I, Takada M, Ohnaka Y, et al. Measurement of serum concentration with radioimmunoassay for carboxyterminal propeptide of type 1 procollagen [English Abstract]. Kaku Igaku 1993;30:563-569.
16. 99mTc-MDP. Normalization by bone mass. Scand J Clin Lab 1986;46:587-592.
17. Fogelman I, Bessent R. Age-related alterations in skeletal metabolism 24-hr wholebody retention of diphosphonate in 250 normal subjects: concise communication. J Nucl Mal 1982;23:296-300.
18. Fogelman I, Ogelman I, Bessent R, Cohen HN, Hart DM, Lindsay R. Skeletal uptake of diphosphonate. Method for prediction of postmenopausal osteoporosis. Lancet 1980;2:667-670.
19. Riis BJ. Biochemical markers of bone turnover II: Diagnosi00s, prophylaxis and treatment of osteoporosis. Am J Med 1993;95:l7s-22s.
20. Christiansen C. Postmenopausal bone loss and the risk of osteoporosis. Osteoporos Int 1994;1:47-51.
21. Flicker L, Lichtenstein M, Colman P, et al. The effect of aging on intact PTH and bone density in women, J Am Geriatr Soc 1992;40:1135-1138.
22. Riggs BL. Overview of osteoporosis. West J Med 1991;154:63-77.
23. Uebelhart D, Schlemmer A, Johansen JS, Gineyts E, Christiansen C, Delmas PD. Effect of menopause and hormone replacement therapy on the urinary excretion of pyridinium cross-links. J Clin Endocrinol Metab 1991; 72:367-373.