The use of normal children as participants in research on therapy

IRB Ethics and Human Research

Volumn 18, Issue 3, 1996, Pages 5-8

  Gordon, Bruce ^a   Prentice, Ernest ^a   Reitemeier, Paul ^b  

^a Department of Pediatrics ^*

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOMEDICAL AND BEHAVIORAL RESEARCH; BLOOD DONOR; BLOOD SAMPLING; BLOOD TRANSFUSION; BONE MARROW; CHILD; DONOR; ETHICS; EXPERIMENTAL THERAPY; GOVERNMENT; GOVERNMENT REGULATION; HEALTH; HUMAN; HUMAN EXPERIMENT; LEUKEMIA; LEUKOCYTE TRANSFUSION; NUCLEAR FAMILY; PROFESSIONAL STANDARD; RESEARCH; RESEARCH SUBJECT; RISK; RISK ASSESSMENT; SIBLING; SOCIAL CONTROL; TRANSPLANTATION; UNIVERSITY OF NEBRASKA MEDICAL CENTER; VOLUNTARY WORKER;

BIOMEDICAL AND BEHAVIORAL RESEARCH; UNIVERSITY OF NEBRASKA MEDICAL CENTER;

BLOOD DONORS; BLOOD SPECIMEN COLLECTION; BLOOD TRANSFUSION; BONE MARROW; CHILD; ETHICAL REVIEW; ETHICS; ETHICS COMMITTEES; ETHICS COMMITTEES, RESEARCH; FEDERAL GOVERNMENT; GOVERNMENT; GOVERNMENT REGULATION; HEALTH; HUMAN EXPERIMENTATION; HUMANS; LEUKEMIA; LEUKOCYTE TRANSFUSION; NONTHERAPEUTIC HUMAN EXPERIMENTATION; NUCLEAR FAMILY; RESEARCH; RESEARCH SUBJECTS; RISK; RISK ASSESSMENT; SIBLINGS; SOCIAL CONTROL, FORMAL; THERAPEUTIC HUMAN EXPERIMENTATION; THERAPIES, INVESTIGATIONAL; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS; UNITED STATES DEPT. OF HEALTH AND HUMAN SERVICES; VOLUNTARY WORKERS;

EID: 0030134544     PISSN: 01937758     EISSN: None     Source Type: Journal    
DOI: 10.2307/3564039     Document Type: Article

References (10)

1. Drobyski, WR, Keever, CA, Roth, MS, et al.: Salvage immunotherapy using donor leukocyte infusion as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation: Efficacy and toxicity of a defined T-cell dose. Blood 1993; 82:2310-18.
2. Bar, BM, Schattenberg, A, Mensink, EJ, et al.: Donor leukocyte infusions for chronic myeloid leukemia relapsed after allogeneic bone marrow transplantation. Journal of Clinical Oncology 1993; 11:513-19.
3. Duhrsen, U, Villeval, JL, Boyd, J, et al.: Effects of recombinant granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients. Blood 1988; 72:2074-81.
4. Ellis, GB: Federal policy for protection of human subjects. In: Report on the Public Forum on Informed Consent in Clinical Research Conducted in Emergency Circumstances. Washington, D.C.: FDA/NIH, May 1995.
5. Fost, N: Children as renal donors. NEJM 1977; 296:363-67.
6. Hart v. Brown, 289 A 2d 386, Conn. 1972.
7. Strunk v. Strunk, 445 S.W. 2d 145 (Ky App., 1969).
8. The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research: Research Involving Children: Report and Recommendations. DHEW Publication No. (OS) 77-0004, Appendix, DHEW Publication No. (OS) 77-0005 (Washington, D.C.: DHEW, 1977).
9. Ackerman, TF: Moral duties of investigators toward sick children. IRB 1981; 3(6):1-5.
10. McCormick, RA: Proxy consent in the experimentation situation. Perspectives on Biology and Medicine 1974; 18:2-20.