Infective pathogenesis and outcomes in chronic bronchitis

Current Opinion in Pulmonary Medicine

Volumn 2, Issue 3, 1996, Pages 181-185

  Ball, Peter ^a  

^a VICTORIA HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; LACTAM; PLACEBO;

ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; BREATHING; BREATHING MECHANICS; BRONCHITIS; BRONCHUS; CHRONIC DISEASE; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; EPITHELIUM; FORECASTING; HAEMOPHILUS INFLUENZAE; HOSPITALIZATION; HUMAN; IMMUNOLOGY; INTENSIVE CARE; MICROBIOLOGY; PRACTICE GUIDELINE; REVIEW; RISK FACTOR; SURVIVAL RATE; TREATMENT FAILURE; TREATMENT OUTCOME;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BRONCHI; BRONCHITIS; CHRONIC DISEASE; CONTROLLED CLINICAL TRIALS; DRUG RESISTANCE, MICROBIAL; EPITHELIUM; FORECASTING; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HOSPITALIZATION; HUMANS; INTENSIVE CARE; LACTAMS; PLACEBOS; PRACTICE GUIDELINES; RESPIRATION; RESPIRATORY MECHANICS; RISK FACTORS; SURVIVAL RATE; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 0030132805     PISSN: 10705287     EISSN: None     Source Type: Journal    
DOI: 10.1097/00063198-199605000-00004     Document Type: Article

References (48)

1. Murphy TF, Sethi S: State of the art: bacterial infection in chronic obstructive pulmonary disease. Am Rev Respir Dis 1992, 146:1067-1083.
2. Kanner RE, Renzetti AD Jr, Klauber MR, Smith CB, Golden CA: Variables associated with spirometry in patients with obstructive lung disease. Am J Med 1979, 67:44-50.
3. Prescott E, Lange P, Vestbo J: Chronic mucus hypersecretion in COPD and death from pulmonary infection. Eur Respir J 1995, 8:1333-1338.
4. Siafakas NM, Vermiere P, Pride NB, Paoletti P, Gibson J, Howard P, Yernault JC, Decramer M, Higenbottam T, Postma DS, Rees J: Optimal assessment and management of chronic obstructive pulmonary disease (COPD). Eur Respir J 1995, 8:1398-1420. This consensus statement on chronic obstructive pulmonary disease by the European Respiratory Society provides standards for the assessment and management of this complex of diseases. It defines criteria for home and hospital management and provides algorithms for investigation and treatment.
5. Gonzales R, Sande MA: What will it take to stop physicians from prescribing antibiotics in acute bronchitis? Lancet 1995, 345:665-666.
6. MacFarlane JT, Colville A, Guion A, MacFarlane RM, Rose DH: Prospective study of aetiology and outcome of adult lower-respiratory-tract infections in the community. Lancet 1993, 341:511-514.
7. Ball P, Harris JM, Lowson D, Tillotson G, Wilson R: Acute infective exacerbations of chronic bronchitis. Q J Med 1991, 88:61-68. The authors describe an observational study of 471 domiciliary patients, concluding that the Winnipeg criteria ( Anthonisen et al. Ann Intern Med 1987, 106:196-204) only define an exacerbation. Clinical criteria did not predict severity, but a return to the practitioner with unresolved symptoms (clinical failure) was predicted by a history of frequent recent exacerbations and coexistent cardiopulmonary morbidity.
8. Ball P, Harris JM, Lowson D, Tillotson G, Wilson R: Acute infective exacerbations of chronic bronchitis. Q J Med 1991, 88:61-68. The authors describe an observational study of 471 domiciliary patients, concluding that the Winnipeg criteria ( Anthonisen et al. Ann Intern Med 1987, 106:196-204) only define an exacerbation. Clinical criteria did not predict severity, but a return to the practitioner with unresolved symptoms (clinical failure) was predicted by a history of frequent recent exacerbations and coexistent cardiopulmonary morbidity.
9. Cole P, Wilson R: Host-microbial relationships in respiratory infection. Chest 1989, 95:217S-221S.
10. van Alphen L, Jansen HM, Dankert J: Virulence factors in the colonization and persistence of bacteria in the airways. Am J Respir Crit Care Med 1995, 151:2094-2099. Mechanisms by which bacteria interact with mucus, exert ciliotoxic activity, adhere to epithelial cells, and invade epithelium are discussed, including the evasion of antibody-mediated defense mechanisms by antigenic variation and persistence of bacteria in the bronchial tree between exacerbations.
11. Wilson R: The pathogenesis and management of bronchial infections: the vicious circle of respiratory decline. Rev Contemp Pharmacother 1992, 3:103-112.
12. van Alphen L, Eijk P, Geelen van den Broek L, Dankert J: Immunochemical characterization of variable epitopes of outer membrane protein P2 of non-typable Haemophilus influenzae. Infect Immun 1991, 59:247-252.
13. Groeneveld KL, van Alphen L, Eijk PP, Visschers G, Jansen HM, Zanen HC: Endogenous and exogenous reinfections by Haemophilus influenzae in patients with chronic obstructive pulmonary disease: the effects of antibiotic treatment upon persistence. J Infect Dis 1990, 161:512-517.
14. Jansen HM, Sachs AP, van Alphen L: Predisposing conditions to bacterial infections in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1995, 151:2073-2080. This paper discusses the pathophysiology of chronic obstructive pulmonary disease in relation to injury, colonization, and invasion by bacteria; the subversion of host-inflammatory processes into production of damage; the effects of specific bacterial products; and the results of infiltration by host cells.
15. Widdicombe J: Relationships among the composition of mucus, epithelial lining fluid and adhesion of microorganisms. Am J Respir Crit Care Med 1995, 151:2088-2093.
16. Stockley RA, Lomas D, Burnett D: Inflammatory indices for chronic bronchitis and COPD: proteases and anti-proteases. Agents Actions Suppl 1990, 30:229-241.
17. Stockley RA: The role of proteinases in the pathogenesis of chronic bronchitis. Am J Respir Crit Care Med 1994, 150:S109-S113.
18. Hoidal JR: Pathogenesis of chronic bronchitis. Semin Respir Infect 1994, 9:8-12.
19. Ruse GC, Ahlsted S, Larsson S, Enander I, Jones I, Larsson P, Andresson B: Bronchial inflammation in chronic bronchitis assessed by measurement of cell products in bronchial lavage fluid. Thorax 1995, 50:360-365. Recruitment and activation of neutrophils associated with IL-8 are characteristic of chronic bronchitis. Pneumococcal infection produced the highest levels of IL-8, eosinophilic cationic protein, and myeloperoxidase in bronchial fluid, and can promote inflammation.
20. Levine SJ: Bronochial epithelial cell-cytokine interactions in airway inflammation. J Invest Med 1995, 43:241-249.
21. Davies BI: Critical review of microbiological data and methods in diagnosis of lower respiratory tract infections. Monaldi Arch Chest Dis 1994, 49:52-56.
22. Ball P, Wilson R: The epidemiology and management of chronic bronchitis, the Cinderella of chest diseases. In Epidemiology and Management of Chronic Bronchitis. Edited by Ball AP, Wilson R. Worthing, UK: Cambridge Medical Publications; 1994:III-IX.
23. Smith CB, Golden CA, Kanner RE, Renzetti AD: Haemophilus influenzae and Haemohilus parainfluenzae in chronic obstructive pulmonary disease. Lancet 1976, 1:1253-1256.
24. Fagon J-Y, Chastre J, Trouillet J-L, Domart Y, Dombret M-C, Bornet M, Gibert C: Characterization of distal bronchial microflora during acute exacerbation of chronic bronchitis. Am Rev Respir Dis 1990, 142:1004-1008.
25. Monso E, Ruiz J, Rosell A, Manterola J, Fiz J, Morera J, Ausina V: Bacterial infection in chronic obstructive airways disease: a study of stable and exacerbated outpatients using the protected specimen brush. Am J Respir Crit Care Med 1995, 152:1316-1320.
26. Sportel JM, Koeter GH, van Altena R, Lowenberg A, Boersma WG: Relation between beta-lactamase producing bacteria and patient characteristics in chronic obstructive pulmonary disease. Thorax 1995, 50:249-253.
27. Schaberg T, Grassi GG, Huchon G, Leophonte P, Manresa F, Woodhead M: An analysis of European general practitioners decisions to hospitalise patients with lower respiratory tract infections. Thorax 1996, in press. Differential patterns of admission and factors relating to admission throughout Europe are analyzed. Exacerbations of chronic bronchitis have a low priority compared with pneumonia; and multivariate analysis indicated that chest pain, cyanosis, hypotension, and dyspnea significantly affect the decision-making process.
28. Fuso L, Incalzi RA, Pistella R, Muzzolon R, Valente S, Pagliari G, Gliozzi F, Ciappi G: Predicting mortality of patients hospitalized for acutely exacerbated chronic obstructive pulmonary disease. Am J Med 1995, 98:272-277. Factors predictive of mortality in 590 hospitalized patients were studied. At the time of admission, cardiac problems including ventricular and atrial arrhythmias, age, and (alone among pulmonary data) the alveolar-arterial oxygen gradient predicted a fatal outcome.
29. Broochard L, Mancebo J, Wysocki M, Lofaso F, Conti G, Rauss A, Simonneau G, Benito S, Gasparetto A, Lemaire F, et al.: Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. N Engl J Med 1995, 333:870-871. In selected patients with AECB, noninvasive ventilation can reduce length of hospital stay, mortality, and the need for intubation.
30. Ball P: Epidemiology and treatment for chronic bronchitis and its exacerbations. Chest 1995, 108:43S-52S.
31. Saint S, Bent S, Vittinghof E, Grady D: Antibiotics in chronic obstructive pulmonary disease exacerbations. JAMA 1995, 273:957-960. The authors performed a meta-analysis of randomized trials of antibiotic therapy for bacterial AECB, concluding that the analyses suggested a small but statistically significant improvement due to antibiotic therapy.
32. Anthonisen NR, Manfreda J, Warren CPW, Hershfeild ES, Harding GKM, Nelson NA: Antibiotic therapy in acute exacerbations of chronic obstructive pulmonary disease. Ann Intern Med 1987, 106:196-204.
33. Allegra L, Grassi C, Grossi E, Possi E: Ruolo degli antibiotici nel trattamento delle riacutizza della bronchite cronica. Ital J Chest Dis 1991, 45:138-148.
34. Munro NC, Cooke JC, Currie DC, Strickland B, Cole PJ: Comparison of thin section computed tomography with bronchography for identifying bronchiectatic segments in patients with chronic sputum production. Thorax 1990, 45:135-139.
35. Wilson R, Tillotson G, Ball P: Future clinical studies in chronic bronchitis: a need for better definition and classification of severity. J Antimicrob Chemother 1996, in press.
36. Balter MS: Recommendations on the management of chronic bronchitis. Can Med Ass J 1994, 151(suppl):1-23.
37. Chodosh S: Treatment of acute exacerbations of chronic bronchitis: state of the art. Am J Med 1991, 91(suppl 6A):87S-92S.
38. Chodos S: Acute bacterial exacerbation of chronic bronchitis. Clin Drug Invest 1995, 1(suppl 1):25-29.
39. Ball P, Wilson R, Tillotson GS: Chemotherapy for chronic bronchitis: controversies. Presse Med 1995, 24:189-194.
40. Sachs APE, Koeter GH, Groenier KH, van der Waaij D, Schiphuis J, Meyboom-de Jong B: Changes in symptoms, peak expiratory flow, and sputum flora during treatment with antibiotics of exacerbations in patients with chronic obstructive airways disease in general practice. Thorax 1995, 50:758-763.
41. Korner RJ, Reeves DS, MacGowan AP: Dangers of oral fluoroquinolone treatment in community acquired respiratory tract infections [letter]. BMJ 1994, 308:191-192.
42. Barton SB, Walley T: Bayer promotional publications misleading about effect of ciprofloxacin on hospital admissions [letter]. Lancet 1995, 346:1102.
43. Ball AP, Tillotson GS: Lower respiratory tract Infection therapy: the role of ciprofloxacin. J Int Med Res 1995, 23:315-327.
44. Ball P: Ofloxacin in exacerbations of chronic bronchitis. Penetration: Annual Issue 1996, 17-21.
45. Henry D, Ruoff GE, Rhudy J, Puopolo A, Drehobl M, Schoenberger J, Giguere G, Collins JJ: Effectiveness of short course therapy (5 days) with cefuroxime axetil in treatment of secondary bacterial infections of acute bronchitis. Antimicrob Agents Chemother 1995, 39:2528-2534.
46. Beghi G, Berni F, Carratu L, Casalini A, Cponsigli G, D'Anto M, Gioia V, Molino A, Paizis G, Vaghi A: Efficacy and tolerability of azithromycin versus amoxicillin-clavulanic acid in acute purulent exacerbations of chronic bronchitis. J Chemother 1995, 7:146-152.
47. Cazzola M, Vinciguerra A, Beghi GF, Paixis G, Giura R, Madonini V, Fiorentini F, Consigli GF, Tonna M, Casalini A, Legnani D: Comparative evaluation of the clinical and microbiological efficacy of co-amoxiclav vs. cefixime or ciprofloxacin in bacterial exacerbation of chronic bronchitis. J Chemother 1995, 7:432-441.
48. Wilson R: Outcome predictors in bronchitis. Chest 1995, 108:53S-57S.